Fulminant bilateral acute retinal necrosis syndrome associated with viral encephalitis: A case report

Zhou,Chunkui; Zhu,Lijun; Fang,Shaokuan

doi:10.3892/etm.2016.3594

October-2016 Volume 12 Issue 4

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October-2016 Volume 12 Issue 4

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Case Report

Fulminant bilateral acute retinal necrosis syndrome associated with viral encephalitis: A case report

Authors:
- Chunkui Zhou
- Lijun Zhu
- Shaokuan Fang
View Affiliations / Copyright

Affiliations: Department of Neurology, The First Teaching Hospital of Jilin University, Changchun, Jilin 130041, P.R. China
Pages: 2227-2229
|
Published online on: August 12, 2016

https://doi.org/10.3892/etm.2016.3594
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Abstract

Herpes simplex virus (HSV) is the most common cause of acute viral encephalitis. Acute retinal necrosis (ARN) is a rapidly progressing and potentially blinding eye disease that may be induced by HSV. The present case study reports the very rare case of a patient with herpes simplex encephalitis (HSE) combined with acute retinal necrosis (ARN). A 47‑year‑old woman was admitted to hospital with persistent high fever and somnolence for 5 days. Magnetic resonance imaging showed abnormal signals in the right medial temporal lobes, and HSV-1 was identified in the serum and cerebrospinal fluid. Five days later, despite treatment with intravenous acyclovir and partial improvement in consciousness, the patient suddenly developed blurred vision and bilateral visual pain. Fundus fluorescence angiography revealed bilateral vessel obstruction and flaky reduced fluorescence. ARN was diagnosed clinically. Dexamethasone was administered as an anti-inﬂammatory adjunct to intravenous acyclovir therapy. The visual acuity of the patient was reduced to mere light perception a further 4 days later. The present case indicates that HSE may be complicated with ARN, causing a reduction in visual acuity to mere light perception within a very short time.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Fulminant bilateral acute retinal necrosis syndrome associated with viral encephalitis: A case report

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