Tissue injuries after single-port and multiport laparoscopic gynecologic surgeries: A prospective multicenter study

So,Kyeong  A; Lee,Jae  Kwan; Song,Jae  Yun; Kim,Jae  Won; Lee,Nak  Woo; Ki,Kyung‑Do; Lee,Jong‑Min; Song,Yong  Jung; Na,Yong  Jin; Ku,Chun  Hoe; Shin,Jin  Woo; Kim,Chul  Jung; Jung,Un  Suk

doi:10.3892/etm.2016.3600

Tissue injuries after single-port and multiport laparoscopic gynecologic surgeries: A prospective multicenter study

Authors:
- Kyeong A So
- Jae Kwan Lee
- Jae Yun Song
- Jae Won Kim
- Nak Woo Lee
- Kyung‑Do Ki
- Jong‑Min Lee
- Yong Jung Song
- Yong Jin Na
- Chun Hoe Ku
- Jin Woo Shin
- Chul Jung Kim
- Un Suk Jung
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Affiliations: Department of Obstetrics and Gynecology, Cheil General Hospital & Women's Healthcare Center, Dankook University College of Medicine, Seoul, Gyeonggi‑do 04619, Republic of Korea, Department of Obstetrics and Gynecology, Korea University Guro Hospital, Seoul, Gyeonggi‑do 08308, Republic of Korea, Department of Obstetrics and Gynecology, Korea University Anam Hospital, Seoul 02841, Republic of Korea, Department of Obstetrics and Gynecology, Korea University Ansan Hospital, Gyeonggi‑do 15355, Republic of Korea, Department of Obstetrics and Gynecology, Kyung Hee University, School of Medicine, Seoul, Gyeonggi‑do 05278, Republic of Korea, Department of Obstetrics and Gynecology, Pusan National University Yangsan Hospital, Yangsan, Gyeongsangnam‑do 50612, Republic of Korea, Department of Obstetrics and Gynecology, Gil Medical Center, Gachon University, Namdong-gu, Incheon 21565, Republic of Korea, Department of Obstetrics and Gynecology, Konyang University Hospital, Konyang University College of Medicine, Daejeon 35365, Republic of Korea, Department of Obstetrics and Gynecology, Hanyang University Guri Hospital, Guri‑si, Gyeonggi‑do 11923, Republic of Korea
Published online on: August 22, 2016 https://doi.org/10.3892/etm.2016.3600
Pages: 2230-2236

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Abstract

The present study focused on the degree of tissue injury following single‑port laparoscopic surgery (SPLS) and multiport laparoscopic surgery (MPLS) for the treatment of various benign gynecologic diseases. A total of 228 patients were prospectively enrolled at seven academic centers in South Korea between April 2011 and September 2012. Of these, 122 patients underwent SPLS and 106 patients underwent MPLS. The serum levels of C‑reactive protein, creatine phosphokinase, lactic dehydrogenase and cancer antigen 125 were measured preoperatively and on postoperative day 4 by immunonephelometry. Cosmetic satisfaction and postoperative pain scores (visual analogue scale) were analyzed. Postoperative changes in the levels of the serum markers were found to be similar between the SPLS and MPLS groups. However, the postoperative pain scores at 48 h were significantly lower in the SPLS group when compared with those in the MPLS (P=0.001). In addition, patient‑controlled analgesia was used more frequently by patients in the MPLS group (P=0.003). The present study is the first prospective investigation of tissue injury resulting from SPLS and MPLS in gynecology. In conclusion, the current study demonstrated that serum marker levels during SPLS were similar to those during MPLS in the treatment of benign gynecologic diseases. However, SPLS is a reasonable alternative to MPLS and is associated with comparable tissue injury, improved cosmesis and reduced postoperative pain.

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