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Review

Parasitic infection as a potential therapeutic tool against rheumatoid arthritis (Review)

  • Authors:
    • Shadike Apaer
    • Tuerhongjiang Tuxun
    • Hai‑Zhang Ma
    • Heng Zhang
    • Amina Aierken
    • Abudusalamu Aini
    • Yu‑Peng Li
    • Ren‑Yong Lin
    • Hao Wen
  • View Affiliations / Copyright

    Affiliations: State Key Laboratory of Xinjiang Major Diseases Research and Xinjiang Key Laboratory of Echinococcosis, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, P.R. China, Department of Ultrasonography, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, P.R. China
  • Pages: 2359-2366
    |
    Published online on: September 5, 2016
       https://doi.org/10.3892/etm.2016.3660
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Abstract

Parasites, which are a recently discovered yet ancient dweller in human hosts, remain a great public health burden in underdeveloped countries, despite preventative efforts. Rheumatoid arthritis is a predominantly cosmopolitan health problem with drastic morbidity rates, although encouraging progress has been achieved regarding treatment. However, although various types of methods and agents have been applied clinically, their broad usage has been limited by their adverse effects and/or high costs. Sustained efforts have been exerted on the ‘hygiene hypothesis’ since the 1870s. The immunosuppressive nature of parasitic infections may offer potential insight into therapeutic strategies for rheumatoid arthritis, in which the immune system is overactivated. An increasing number of published papers are focusing on the preventive and/or curative effect of various parasitic infection on rheumatoid arthritis from experimental studies to large‑scale epidemiological studies and clinical trials. Therefore, the present review aimed to provide a general literature review on the possible beneficial role of parasitic infection on rheumatoid arthritis.
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Copy and paste a formatted citation
Spandidos Publications style
Apaer S, Tuxun T, Ma HZ, Zhang H, Aierken A, Aini A, Li YP, Lin RY and Wen H: Parasitic infection as a potential therapeutic tool against rheumatoid arthritis (Review). Exp Ther Med 12: 2359-2366, 2016.
APA
Apaer, S., Tuxun, T., Ma, H., Zhang, H., Aierken, A., Aini, A. ... Wen, H. (2016). Parasitic infection as a potential therapeutic tool against rheumatoid arthritis (Review). Experimental and Therapeutic Medicine, 12, 2359-2366. https://doi.org/10.3892/etm.2016.3660
MLA
Apaer, S., Tuxun, T., Ma, H., Zhang, H., Aierken, A., Aini, A., Li, Y., Lin, R., Wen, H."Parasitic infection as a potential therapeutic tool against rheumatoid arthritis (Review)". Experimental and Therapeutic Medicine 12.4 (2016): 2359-2366.
Chicago
Apaer, S., Tuxun, T., Ma, H., Zhang, H., Aierken, A., Aini, A., Li, Y., Lin, R., Wen, H."Parasitic infection as a potential therapeutic tool against rheumatoid arthritis (Review)". Experimental and Therapeutic Medicine 12, no. 4 (2016): 2359-2366. https://doi.org/10.3892/etm.2016.3660
Copy and paste a formatted citation
x
Spandidos Publications style
Apaer S, Tuxun T, Ma HZ, Zhang H, Aierken A, Aini A, Li YP, Lin RY and Wen H: Parasitic infection as a potential therapeutic tool against rheumatoid arthritis (Review). Exp Ther Med 12: 2359-2366, 2016.
APA
Apaer, S., Tuxun, T., Ma, H., Zhang, H., Aierken, A., Aini, A. ... Wen, H. (2016). Parasitic infection as a potential therapeutic tool against rheumatoid arthritis (Review). Experimental and Therapeutic Medicine, 12, 2359-2366. https://doi.org/10.3892/etm.2016.3660
MLA
Apaer, S., Tuxun, T., Ma, H., Zhang, H., Aierken, A., Aini, A., Li, Y., Lin, R., Wen, H."Parasitic infection as a potential therapeutic tool against rheumatoid arthritis (Review)". Experimental and Therapeutic Medicine 12.4 (2016): 2359-2366.
Chicago
Apaer, S., Tuxun, T., Ma, H., Zhang, H., Aierken, A., Aini, A., Li, Y., Lin, R., Wen, H."Parasitic infection as a potential therapeutic tool against rheumatoid arthritis (Review)". Experimental and Therapeutic Medicine 12, no. 4 (2016): 2359-2366. https://doi.org/10.3892/etm.2016.3660
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