Promising effects of Chinese traditional treatment for child typhoid complicated by myocarditis

Tian,Jing; An,Xinjiang; Fu,Mingyu; Wang,Qingwen

doi:10.3892/etm.2016.3803

Promising effects of Chinese traditional treatment for child typhoid complicated by myocarditis

Authors:
- Jing Tian
- Xinjiang An
- Mingyu Fu
- Qingwen Wang
View Affiliations

Affiliations: Department of Cardiology, Xuzhou Children's Hospital, Xuzhou, Jiangsu 221002, P.R. China
Published online on: October 12, 2016 https://doi.org/10.3892/etm.2016.3803
Pages: 3557-3560
Copyright: © Tian et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

The clinical effects were compared and analyzed of traditional Chinese medicine (TCM) ‘Ling Gui Long Mu soup’ combined with the conventional Western medications in treating child typhoid complicated by myocarditis. From July, 2010 to May, 2014, 54 children suffering from typhoid complicated by myocarditis were enrolled in the present study. The patients were divided into the observation and control groups (n=27 cases per group) according to the random number table. Patients in the observation group were treated with basic Western medicine combined with TCM ‘Ling Gui Long Mu soup’ while patients in the control group were treated only with Western medicine. We analyzed the final curative effects in the two groups. The total effective rate in the observation group was significantly higher than that of the control group and the difference was statistically significant (P<0.05). The improvement rate of the syndrome in the TCM observation group was significantly higher than that in the control group and the difference was statistically significant (P<0.05). Although the C-reactive protein (CRP) and creatinine kinase-MB (CK-MB) levels in the two groups were decreased following the treatment, CRP and CK-MB levels in the observation group were further reduced, and the difference was statistically significant (P<0.05). In conclusion, for child typhoid complicated by myocarditis, TCM ‘Ling Gui Long Mu soup’ significantly improved the clinical efficiency of the treatment and improved the syndrome. Therefore, ‘Ling Gui Long Mu soup’ is useful in clinical practice.

View Figures

View References

1	Buckle GC, Walker CLF and Black RE: Typhoid fever and paratyphoid fever: Systematic review to estimate global morbidity and mortality for 2010. J Glob Health. 2:104012012. View Article : Google Scholar
2	Gilman RH, Terminel M, Levine MM, Hernandez-Mendoza P and Hornick RB: Relative efficacy of blood, urine, rectal swab, bone-marrow, and rose-spot cultures for recovery of Salmonella typhi in typhoid fever. Lancet. 1:1211–1213. 1975. View Article : Google Scholar : PubMed/NCBI
3	Allymehr M: Seroprevalence of Ornithobacterium rhinotracheale infection in broiler and broiler breeder chickens in West Azerbaijan Province, Iran. J Vet Med A Physiol Pathol Clin Med. 53:40–42. 2006. View Article : Google Scholar : PubMed/NCBI
4	Liu ZL, Liu ZJ, Liu JP, Yang M and Kwong J: Herbal medicines for viral myocarditis. Cochrane Database Syst Rev. 7:CD0037112010.
5	Banani M, Pourbakhsh SA and Deihim AH: Antibiotic sensitivity of Ornithobacterium rhinotracheale isolates associated with respiratory diseases. Arch Razi Ins. 58:111–117. 2004.
6	Yang HH, Wu CG, Xie GZ, Gu QW, Wang BR, Wang LY, Wang HF, Ding ZS, Yang Y, Tan WS, et al: Efficacy trial of Vi polysaccharide vaccine against typhoid fever in south-western China. Bull World Health Organ. 79:625–631. 2001.PubMed/NCBI
7	García M: Typhoid fever in nineteenth-century Colombia: between medical geography and bacteriology. Med Hist. 58:27–45. 2014. View Article : Google Scholar : PubMed/NCBI
8	Kaljee LM, Pach A, Thriemer K, Ley B, Ali SM, Jiddawi M, Puri M, von Seidlein L, Deen J, Ochiai L, et al: Utilization and accessibility of healthcare on Pemba Island, Tanzania: implications for health outcomes and disease surveillance for typhoid fever. Am J Trop Med Hyg. 88:144–152. 2013. View Article : Google Scholar : PubMed/NCBI
9	Mweu E and English M: Typhoid fever in children in Africa. Trop Med Int Health. 13:532–540. 2008. View Article : Google Scholar : PubMed/NCBI
10	Moore CE, Pan-Ngum W, Wijedoru LP, Sona S, Nga TV, Duy PT, Vinh PV, Chheng K, Kumar V, Emary K, et al: Evaluation of the diagnostic accuracy of a typhoid IgM flow assay for the diagnosis of typhoid fever in Cambodian children using a Bayesian latent class model assuming an imperfect gold standard. Am J Trop Med Hyg. 90:114–120. 2014. View Article : Google Scholar : PubMed/NCBI
11	Andualem G, Abebe T, Kebede N, Gebre-Selassie S, Mihret A and Alemayehu H: A comparative study of Widal test with blood culture in the diagnosis of typhoid fever in febrile patients. BMC Res Notes. 7:6532014. View Article : Google Scholar : PubMed/NCBI
12	Khoo SK, Petillo D, Parida M, Tan AC, Resau JH and Obaro SK: Host response transcriptional profiling reveals extracellular components and ABC (ATP-binding cassette) transporters gene enrichment in typhoid fever-infected Nigerian children. BMC Infect Dis. 11:2412011. View Article : Google Scholar : PubMed/NCBI
13	Ley B, Mtove G, Thriemer K, Amos B, von Seidlein L, Hendriksen I, Mwambuli A, Shoo A, Malahiyo R, Ame SM, et al: Evaluation of the Widal tube agglutination test for the diagnosis of typhoid fever among children admitted to a rural hdospital in Tanzania and a comparison with previous studies. BMC Infect Dis. 10:1802010. View Article : Google Scholar : PubMed/NCBI
14	Xie DY and Chen RX: The two-step location method of acupoint in Internal Canon of Medicine and its clinical application. Zhongguo Zhen Jiu. 34:979–982. 2014.(In Chinese). PubMed/NCBI
15	Wijedoru LPM, Kumar V, Chanpheaktra N, Chheng K, Smits HL, Pastoor R, Nga TV, Baker S, Wuthiekanun V, Peacock SJ, et al: Typhoid fever among hospitalized febrile children in Siem Reap, Cambodia. J Trop Pediatr. 58:68–70. 2012. View Article : Google Scholar : PubMed/NCBI
16	Khanam F, Sayeed MA, Choudhury FK, Sheikh A, Ahmed D, Goswami D, Hossain ML, Brooks A, Calderwood SB, Charles RC, et al: Typhoid fever in young children in Bangladesh: clinical findings, antibiotic susceptibility pattern and immune responses. PLoS Negl Trop Dis. 9:e00036192015. View Article : Google Scholar : PubMed/NCBI