Open Access

Long-term prognostic analysis of early interventional therapy for lower extremity deep venous thrombosis

  • Authors:
    • Qiang Li
    • Zongxue Yu
    • Jinjun Wang
    • Xiao Chen
    • Lin Li
  • View Affiliations

  • Published online on: October 18, 2016     https://doi.org/10.3892/etm.2016.3812
  • Pages: 3545-3548
  • Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The aim of the present study was to observe the long-term prognostic value of early interventional therapy for lower extremity deep venous thrombosis (LDVT). In total, 85 patients diagnosed with LDVT for the first time were consecutively selected (identified course of disease was <3 months), and were divided into the control group with 43 cases and the observation group with 42 cases according to different therapeutic methods. The control group received anticoagulation therapy and thrombolysis, or integrated surgical thrombectomy, a conventional open operation, while the observation group received comprehensive treatment, combining endovascular catheter-directed thrombolysis and thrombectomy. The therapeutic effects were compared. After treatment, the differences in circumference of the thigh and shank between the affected and unaffected extremities, and vein dysfunction score of the two groups were decreased compared with before treatment. In addition, the above indexes of the observation group were significantly lower than in the control group (P<0.05). The clinical effective rate and effective extent of the observation group were higher than those of the control group, and the differences were statistically significant (P<0.05). The occurrence rate of post-thrombotic syndrome in the observation group was lower than that of the control group, and there was no difference in comparison of grading. The recurrence rate and restenosis rate of the observation group were lower than in the control group, while the patency rate of the observation group was higher than that of the control group, and the differences were statistically significant (P<0.05). In conclusion, early catheter-directed invention of thrombolysis with thrombectomy for LDVT has good clinical effect in the short-term and long-term.
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December-2016
Volume 12 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Li Q, Yu Z, Wang J, Chen X and Li L: Long-term prognostic analysis of early interventional therapy for lower extremity deep venous thrombosis. Exp Ther Med 12: 3545-3548, 2016
APA
Li, Q., Yu, Z., Wang, J., Chen, X., & Li, L. (2016). Long-term prognostic analysis of early interventional therapy for lower extremity deep venous thrombosis. Experimental and Therapeutic Medicine, 12, 3545-3548. https://doi.org/10.3892/etm.2016.3812
MLA
Li, Q., Yu, Z., Wang, J., Chen, X., Li, L."Long-term prognostic analysis of early interventional therapy for lower extremity deep venous thrombosis". Experimental and Therapeutic Medicine 12.6 (2016): 3545-3548.
Chicago
Li, Q., Yu, Z., Wang, J., Chen, X., Li, L."Long-term prognostic analysis of early interventional therapy for lower extremity deep venous thrombosis". Experimental and Therapeutic Medicine 12, no. 6 (2016): 3545-3548. https://doi.org/10.3892/etm.2016.3812