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Case Report

Severe pneumonia due to infection with Candida krusei in a case of suspected Middle East respiratory syndrome: A case report and literature review

  • Authors:
    • Mingming Tan
    • Junwei Wang
    • Peiyang Hu
    • Bin Wang
    • Wanghua Xu
    • Jiao Chen
  • View Affiliations / Copyright

    Affiliations: Emergency Department, Tiantai County People's Hospital, Taizhou, Zhejiang 317200, P.R. China
  • Pages: 4085-4088
    |
    Published online on: November 11, 2016
       https://doi.org/10.3892/etm.2016.3892
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Abstract

Candida krusei (C. krusei) pneumonia is a rare infection that is frequently associated with a poor outcome. The present study reports an unusual case of C. krusei pneumonia that was initially suspected to be a Middle East respiratory syndrome (MERS) case. A 64‑year‑old Saudi Arabian male patient was admitted to our hospital with complaints of cough and dyspnea that persisted for 6 days. The patient presented fever (oral temperature, 38.5˚C) and slight tachypnea (25 respirations/min). A chest computerized tomography demonstrated unclear lung fields, diffuse pathological changes in the two lungs and multiple lymphadenectasis in the retrocaval and para‑aortic arch area. The patient received 95‑98% oxygen (6 l/min) for 24 h, as well as sulbactam sodium/cefoperazone sodium (1:1) injection (3.0 g) every 12 h, oral oseltamivir capsules (75 mg/time) twice a day, medaron injection (80 mg/time) and 750 ml fluid infusion; however, he succumbed to the disease on day 2 after admission. The infection was diagnosed by sputum smear and culture subsequent to patient mortality. A sputum smear showed a large fungal infection and sputum culture revealed the presence of C. krusei infection. Serum procalcitonin concentrations were 4.73 µg/l and 7.23 µg/l on days 2 and 3 after admission, respectively. In conclusion, the diagnosis of Candida pneumonia should be strongly considered in the presence of growth of Candida from a sputum culture and based on a suggestive computed tomography image. Tumescent diaphragmatic lymph nodes may also be an important symptom of Candida pneumonia. Treatment should be initiated immediately to improve tissue oxygenation, restore cardiovascular function and improve other organ functions.
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Copy and paste a formatted citation
Spandidos Publications style
Tan M, Wang J, Hu P, Wang B, Xu W and Chen J: Severe pneumonia due to infection with Candida krusei in a case of suspected Middle East respiratory syndrome: A case report and literature review. Exp Ther Med 12: 4085-4088, 2016.
APA
Tan, M., Wang, J., Hu, P., Wang, B., Xu, W., & Chen, J. (2016). Severe pneumonia due to infection with Candida krusei in a case of suspected Middle East respiratory syndrome: A case report and literature review. Experimental and Therapeutic Medicine, 12, 4085-4088. https://doi.org/10.3892/etm.2016.3892
MLA
Tan, M., Wang, J., Hu, P., Wang, B., Xu, W., Chen, J."Severe pneumonia due to infection with Candida krusei in a case of suspected Middle East respiratory syndrome: A case report and literature review". Experimental and Therapeutic Medicine 12.6 (2016): 4085-4088.
Chicago
Tan, M., Wang, J., Hu, P., Wang, B., Xu, W., Chen, J."Severe pneumonia due to infection with Candida krusei in a case of suspected Middle East respiratory syndrome: A case report and literature review". Experimental and Therapeutic Medicine 12, no. 6 (2016): 4085-4088. https://doi.org/10.3892/etm.2016.3892
Copy and paste a formatted citation
x
Spandidos Publications style
Tan M, Wang J, Hu P, Wang B, Xu W and Chen J: Severe pneumonia due to infection with Candida krusei in a case of suspected Middle East respiratory syndrome: A case report and literature review. Exp Ther Med 12: 4085-4088, 2016.
APA
Tan, M., Wang, J., Hu, P., Wang, B., Xu, W., & Chen, J. (2016). Severe pneumonia due to infection with Candida krusei in a case of suspected Middle East respiratory syndrome: A case report and literature review. Experimental and Therapeutic Medicine, 12, 4085-4088. https://doi.org/10.3892/etm.2016.3892
MLA
Tan, M., Wang, J., Hu, P., Wang, B., Xu, W., Chen, J."Severe pneumonia due to infection with Candida krusei in a case of suspected Middle East respiratory syndrome: A case report and literature review". Experimental and Therapeutic Medicine 12.6 (2016): 4085-4088.
Chicago
Tan, M., Wang, J., Hu, P., Wang, B., Xu, W., Chen, J."Severe pneumonia due to infection with Candida krusei in a case of suspected Middle East respiratory syndrome: A case report and literature review". Experimental and Therapeutic Medicine 12, no. 6 (2016): 4085-4088. https://doi.org/10.3892/etm.2016.3892
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