VanWyk‑Grumbach syndrome in a male pediatric patient: A rare case report and literature review

  • Authors:
    • Shanshan Zhang
    • Jingyan Yang
    • Rongxiu Zheng
    • Lihong Jiang
    • Ying Wei
    • Geli Liu
  • View Affiliations

  • Published online on: January 24, 2017     https://doi.org/10.3892/etm.2017.4086
  • Pages: 1151-1154
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Abstract

Primary hypothyroidism usually leads to retardation of linear growth and delay or even arrest of puberty in juvenile patients. In rare cases, pediatric patients with hypothyroidism may present with signs of VanWyk‑Grumbach's syndrome (VWGS), which includes juvenile hypothyroidism, delayed bone age and pseudoprecocious puberty. The present study reported on a rare case of VWGS and other complications, including obesity, short stature, hepatomegaly and pituitary hyperplasia. In addition, a comprehensive literature review was performed to illustrate the treatment and outcome of VWGS in pediatric patients. The present study contributed to the current knowledge regarding the diagnosis and treatment of VWGS in pediatric patients.
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March-2017
Volume 13 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Zhang S, Yang J, Zheng R, Jiang L, Wei Y and Liu G: VanWyk‑Grumbach syndrome in a male pediatric patient: A rare case report and literature review. Exp Ther Med 13: 1151-1154, 2017
APA
Zhang, S., Yang, J., Zheng, R., Jiang, L., Wei, Y., & Liu, G. (2017). VanWyk‑Grumbach syndrome in a male pediatric patient: A rare case report and literature review. Experimental and Therapeutic Medicine, 13, 1151-1154. https://doi.org/10.3892/etm.2017.4086
MLA
Zhang, S., Yang, J., Zheng, R., Jiang, L., Wei, Y., Liu, G."VanWyk‑Grumbach syndrome in a male pediatric patient: A rare case report and literature review". Experimental and Therapeutic Medicine 13.3 (2017): 1151-1154.
Chicago
Zhang, S., Yang, J., Zheng, R., Jiang, L., Wei, Y., Liu, G."VanWyk‑Grumbach syndrome in a male pediatric patient: A rare case report and literature review". Experimental and Therapeutic Medicine 13, no. 3 (2017): 1151-1154. https://doi.org/10.3892/etm.2017.4086