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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2017 Volume 13 Issue 3

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Impact Factor: 2.2

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Role of neural barriers in the pathogenesis and outcome of Streptococcus pneumoniae meningitis (Review)

Ofer Prager, Alon Friedman, Yaffa Mizrachi Nebenzahl
Pages: 799-809
Published online on: 24 January 2017

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Review Open Access

PCSK9 as a therapeutic target for cardiovascular disease (Review)

Pei-Ying Zhang
Pages: 810-814
Published online on: 17 January 2017

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Review Open Access

CaMKII: The molecular villain that aggravates cardiovascular disease (Review)

Peiying Zhang
Pages: 815-820
Published online on: 11 January 2017

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Article Open Access

Protective effects of silymarin against bisphenol A-induced hepatotoxicity in mouse liver

Mihaela Zaulet, Steliana Elvira Maria Kevorkian, Sorina Dinescu, Coralia Cotoraci, Maria Suciu, Hildegard Herman, Laura Buburuzan, Liliana Badulescu, Aurel Ardelean, Anca Hermenean
Pages: 821-828
Published online on: 20 January 2017

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Article Open Access

Vascular response profiles following a nano polymer‑free sirolimus‑eluting stent implantation assessed by optical coherence tomography in a porcine model

Li Ma, Qiang Fu, Hongyu Hu, Wei Chen, Li Li, Zhixu Tan, Buxing Chen
Pages: 829-834
Published online on: 19 January 2017

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Article Open Access

Atorvastatin attenuates plaque vulnerability by downregulation of EMMPRIN expression via COX‑2/PGE2 pathway

Xing Liang, Li‑Xia Yang, Ruiwei Guo, Yankun Shi, Xianhua Hou, Zhihua Yang, Xiaobin Zhou, Hong Liu
Pages: 835-844
Published online on: 19 January 2017

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Article Open Access

Tailored treatment for the management of scleral necrosis following pterygium excision

Linna Lu, Shiqiong Xu, Shengfang Ge, Chunyi Shao, Zi Wang, Xuyang Weng, Wenjuan Lu, Xinhua Wu, Yao Fu, Xianqun Fan
Pages: 845-850
Published online on: 12 January 2017

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Article Open Access

Impact of gabapentin on neuronal high voltage‑activated Ca2+ channel properties of injured‑side axotomized and adjacent uninjured dorsal root ganglions in a rat model of spinal nerve ligation

Minmin Zhu, Xiaodi Sun, Xiaodong Chen, Hang Xiao, Manlin Duan, Jianguo Xu
Pages: 851-860
Published online on: 20 January 2017

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Article Open Access

Effect of hypoxia‑inducible factor‑1/vascular endothelial growth factor signaling pathway on spinal cord injury in rats

Hailong Chen, Junjie Li, Shuhan Liang, Bin Lin, Qi Peng, Peng Zhao, Jiawei Cui, Yaojian Rao
Pages: 861-866
Published online on: 16 January 2017

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Article Open Access

Propofol inhibits expression of angiotensin II receptor type 2 in dorsal root ganglion neurons

Bingbing Pan, Zhigang Cheng, Gaoyin Kong, Zongbin Song, Yunjiao Wang, Lai Wei, Dan Xiao, Yuan Zhao, Qulian Guo
Pages: 867-872
Published online on: 12 January 2017

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Article Open Access

Effects of the modified electric convulsive treatment (MECT) on cell factors of schizophrenia

Yong‑Fang Guo, Hua‑Bin Fu, Zhi‑Yuan Liu, Wei Lu, Ke‑Yong Luo, Hong‑Ri Zhu, Wei‑Dong Ning, Feng Chen, Li-Yu Yang, Xiao-Dong Zhou
Pages: 873-876
Published online on: 20 January 2017

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Article Open Access

Orally administered simvastatin partially preserves lumbar vertebral bone mass but not integrity of intervertebral discs in ovariectomized rats

Fa‑Ming Tian, Shu‑Yang Li, Kai Yang, Yang Luo, Mu‑Wei Dai, Guang‑Yuan Liu, Hui‑Ping Song, Liu Zhang
Pages: 877-884
Published online on: 13 January 2017

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Article Open Access

Syringe needle skull penetration reduces brain injuries and secondary inflammation following intracerebral neural stem cell transplantation

Mou Gao, Qin Dong, Hongtian Zhang, Yang Yang, Jianwei Zhu, Zhijun Yang, Minhui Xu, Ruxiang Xu
Pages: 885-890
Published online on: 17 January 2017

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Article Open Access

Emulsified isoflurane combined with therapeutic hypothermia improves survival and neurological outcomes in a rat model of cardiac arrest

Meng‑Jun Wu, Ya‑Jie Zhang, Hai Yu, Bin Liu
Pages: 891-898
Published online on: 13 January 2017

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Article Open Access

Exercise training on chronotropic response and exercise capacity in patients with type 2 diabetes mellitus

Li Jin, Gao Min, Chen Wei, He Min, Zhou Jie
Pages: 899-904
Published online on: 24 January 2017

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Article Open Access

Diagnostic value of high-frequency color Doppler ultrasonography examination in combination with anti-cyclic citrullinated peptide antibody testing in rheumatoid arthritis patients

Ming‑Yu Wang, Xian‑Bin Wang, Xue‑Hui Sun, Feng‑Li Liu, Sheng‑Chuan Huang
Pages: 905-908
Published online on: 17 January 2017

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Article Open Access

Association between the extent of white matter damage and early cognitive impairment following acute ischemic stroke

Jian Li, Yong Zhao, Jinying Mao
Pages: 909-912
Published online on: 11 January 2017

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Article Open Access

Areas of breast tissue covered in cone beam breast CT imaging

Min Xu, Xue Cheng, Xingyao Cheng, Xilin Lan, Shuzheng Chen, Jiansong Ji
Pages: 913-916
Published online on: 27 January 2017

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Article Open Access

Detection and analysis of hepatitis C virus in HIV-infected patients in the Guangxi province of China

Shu‑Zhi Wu, Jin‑Lu Wei, Bin Xu, Peng‑Hai Wei, Yan Yang, Bin Qin, Zhi‑Chun Xie
Pages: 917-923
Published online on: 20 January 2017

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Article Open Access

Research on the effect of ginseng polysaccharide on apoptosis and cell cycle of human leukemia cell line K562 and its molecular mechanisms

Wei Xiong, Jing Li, Rong Jiang, Danyang Li, Zehong Liu, Dilong Chen
Pages: 924-934
Published online on: 24 January 2017

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Article Open Access

MicroRNA‑17‑5p mediates hypoxia‑induced autophagy and inhibits apoptosis by targeting signal transducer and activator of transcription 3 in vascular smooth muscle cells

Ming‑Xiu Hao, Xing Wang, Kun‑Li Jiao
Pages: 935-941
Published online on: 16 January 2017

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Article Open Access

Expression and roles of TIPE2 in autoimmune hepatitis

Jinhua Qian, Zongde Meng, Jiachang Guan, Zhiwei Zhang, Yangang Wang
Pages: 942-946
Published online on: 16 January 2017

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Article Open Access

Significance of combined detection of JAK2V617F, MPL and CALR gene mutations in patients with essential thrombocythemia

Liying Ji, Mengyao Qian, Nana Wu, Jianmin Wu
Pages: 947-951
Published online on: 23 January 2017

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Article Open Access

Therapeutic effect of apocynin through antioxidant activity and suppression of apoptosis and inflammation after spinal cord injury

Yijun Sun, Futai Gong, Jichao Yin, Xiaoyan Wang, Xiangyang Wang, Qing Sun, Zhiqiang Zhu, Xiaoqiang Su, Jie Zheng, Li Liu, Yang Li, Xinglv Hu, Jia Li
Pages: 952-960
Published online on: 25 January 2017

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Article Open Access

Effects of weight training time on bone mineral density of patients with secondary osteoporosis after hemiplegia

Liang Han, Shu-Gang Li, Hong-Wei Zhai, Peng-Fei Guo, Wei Chen
Pages: 961-965
Published online on: 23 January 2017

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Article Open Access

Application of 3D-HyCoSy in the diagnosis of oviduct obstruction

Jinglei Wang, Jingbo Li, Ling Yu, Suhua Han, Xiaofang Shen, Xiao Jia
Pages: 966-970
Published online on: 24 January 2017

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Article Open Access

Effect of etomidate on the oxidative stress response and levels of inflammatory factors from ischemia-reperfusion injury after tibial fracture surgery

Renke Li, Lei Fan, Fenglei Ma, Yongyan Cao, Junwei Gao, Huawen Liu, Yan Li
Pages: 971-975
Published online on: 12 January 2017

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Article

Effect of intranasal stem cell administration on the nigrostriatal system in a mouse model of Parkinson's disease

Mohamed Salama, Mahmoud Sobh, Mahmoud Emam, Ahmed Abdalla, Dina Sabry, Mohamed El‑Gamal, Ahmed Lotfy, Mahmoud El‑Husseiny, Mohamed Sobh, Ali Shalash, Wael My Mohamed
Pages: 976-982
Published online on: 20 January 2017

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Article

Epidemiological analysis of 9,596 patients with acute lung injury at Chinese Military Hospitals

Daijun Zhou, Jun Qiu, Yi Liang, Wei Dai, Danfeng Yuan, Jihong Zhou
Pages: 983-988
Published online on: 20 January 2017

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Article

Cell penetrating peptide of sodium‑iodide symporter effect on the I‑131 radiotherapy on thyroid cancer

Yi‑Xiang Fan, Zhi‑Xin Liang, Qing‑Zhu Liu, Han Xiao, Ke‑Bin Li, Ji‑Zhen Wu
Pages: 989-994
Published online on: 23 January 2017

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Article

Echocardiographic characterization of hypertrophic cardiomyopathy in Chinese patients with myosin-binding protein C3 mutations

Bei Zhao, Shouli Wang, Jinsong Chen, Yali Ji, Jing Wang, Xiaoli Tian, Guang Zhi
Pages: 995-1002
Published online on: 25 January 2017

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Article

Retrospective analysis of fosfomycin combinational therapy for sepsis caused by carbapenem-resistant Klebsiella pneumoniae

Yun Liao, Guang‑Hui Hu, Yun‑Fei Xu, Jian‑Ping Che, Ming Luo, Hai‑Min Zhang, Bo Peng, Xu‑Dong Yao, Jun‑Hua Zheng, Min Liu
Pages: 1003-1010
Published online on: 16 January 2017

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Article

Microscopic surgery for pituitary adenomas to preserve the pituitary gland and stalk

Hao‑Yu Li, Cheng‑Yuan Feng, Chi Zhang, Jun Su, Jian Yuan, Yuanyang Xie, Yiwei Liao, Xianrui Yuan, Qing Liu
Pages: 1011-1016
Published online on: 19 January 2017

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Article

MicroRNA-138 inhibits hypoxia-induced proliferation of endothelial progenitor cells via inhibition of HIF-1α-mediated MAPK and AKT signaling Retraction in /10.3892/etm.2021.10428

Wei Zhou, Weimin Zhou, Qingzhong Zeng, Jixin Xiong
Pages: 1017-1024
Published online on: 27 January 2017

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Article

The traditional Korean herbal medicine Ga-Gam-Nai-Go-Hyan suppresses testosterone-induced benign prostatic hyperplasia by regulating inflammatory responses and apoptosis

Su‑Jin Shin, Kwang‑Ho Lee, Kyung‑Sook Chung, Se‑Yun Cheon, Hyo‑Jin An
Pages: 1025-1031
Published online on: 25 January 2017

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Article

Whole extracts of Radix Achyranthis Bidentatae and Radix Cyathulae promote angiogenesis in human umbilical vein endothelial cells in vitro and in zebrafish in vivo

Xuelin Zhou, Wing‑Sum Siu, Cheng Zhang, Cheuk‑Lun Liu, Ling Cheng, Hin‑Fai Kwok, Chak‑Hei Fung, Jacqueline Chor‑Wing Tam, Ching‑Po Lau, Clara Bik‑San Lau, Ping‑Chung Leung, Leung‑Kim Hung, Chun‑Hay Ko
Pages: 1032-1038
Published online on: 17 January 2017

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Article

Isolation, culture and identification of human adipose-derived stem cells

Jian‑Mei Wang, Yan Gu, Cai‑Jun Pan, Li‑Rong Yin
Pages: 1039-1043
Published online on: 20 January 2017

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Article

Genome‑scale transcriptional analysis reveals key genes associated with the development of type II diabetes in mice

Yuchi Zhang, Dongwei Han, Pengyang Yu, Qijing Huang, Pengling Ge
Pages: 1044-1150
Published online on: 13 January 2017

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Case Report

Langerhans' cell histiocytosis of the temporal bone: A case report

Maomei Ni, Xiuhai Yang
Pages: 1051-1053
Published online on: 20 January 2017

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Case Report

Rapidly progressive rhino-orbito-cerebral mucormycosis in a patient with type 2 diabetes: A case report

Yan‑Xia Chen, Yin‑Xi He, Hong Zhou, Mian Wang, Sheng‑Ou Su
Pages: 1054-1056
Published online on: 20 January 2017

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Article

Immunohistochemical analysis of microsomal glutathione S‑transferase 1 and clusterin expression in lens epithelial cells of patients with pseudoexfoliation syndrome

Joanna Stafiej, Marta Hałas‑Wiśniewska, Magdalena Izdebska, Maciej Gagat, Dariusz Grzanka, Alina Grzanka, Grażyna Malukiewicz
Pages: 1057-1063
Published online on: 24 January 2017

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Article

Clinicopathological significance of ROCK1 and PIK3CA expression in nasopharyngeal carcinoma

Xuanyi Wang, Yuxiang Huang, Renhua Guo, Yongbiao Liu, Yayun Qian, Dan Liu, Xiaojun Dai, Zheng Wei, Feng Jin, Yanqing Liu
Pages: 1064-1068
Published online on: 23 January 2017

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Article

Evaluation of optimized magnetic resonance perfusion imaging scanning time window after contrast agent injection for differentiating benign and malignant breast lesions

Jie Dong, Dawei Wang, Zhenshen Ma, Guodong Deng, Lanhua Wang, Jiandong Zhang
Pages: 1069-1073
Published online on: 18 January 2017

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Article

Bupivacaine effectively relieves inflammation‑induced pain by suppressing activation of the NF‑κB signalling pathway and inhibiting the activation of spinal microglia and astrocytes

Jingliang Zhang, Xinlian Deng
Pages: 1074-1080
Published online on: 18 January 2017

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Article

Effect of vacuum sealing drainage on the expression of VEGF and miRNA‑17‑5p in seawater‑immersed blast‑injury wounds

Fen Yang, Bing Shi, Ling Cao
Pages: 1081-1086
Published online on: 18 January 2017

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Article

The inflammatory cytokine IL‑22 promotes murine gliomas via proliferation

Xiguo Liu, Junjing Yang, Wankai Deng
Pages: 1087-1092
Published online on: 18 January 2017

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Article

Preventative effects of fermented Chimonobambusa quadrangularis shoot on activated carbon‑induced constipation

Guijie Li, Xiaochuan Zou, Gang Kuang, Yanrong Ren, Chaofang Deng, Qiang Lin, Xin Zhao, Song Xu, Jia‑Le Song
Pages: 1093-1100
Published online on: 11 January 2017

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Article

Genetic variation in the 3'‑untranslated region of PAK1 influences schizophrenia susceptibility

Juan Jiang, Jianxiong Long, Weijun Ling, Guifeng Huang, Li Su
Pages: 1101-1108
Published online on: 12 January 2017

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Article

Efficacy and tolerability of once‑daily 160 mg valsartan in Chinese patients with mild to moderate hypertension

Ningling Sun, Yingqing Feng, Pingjin Gao, Xiaoping Chen, Litong Qi, Shuyang Zhang, Yugang Dong, Xinchun Yang, Xinli Li, Yundai Chen, Lingli Liu
Pages: 1109-1116
Published online on: 17 January 2017

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Article

Characteristics of carbapenemase-producing Klebsiella pneumoniae as a cause of neonatal infection in Shandong, China

Yan Jin, Xiaofei Song, Yigang Liu, Yong Wang, Bingchang Zhang, Hui Fan, Chunhong Shao
Pages: 1117-1126
Published online on: 20 January 2017

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Article

MicroRNA‑185 regulates spinal cord injuries induced by thoracolumbar spine compression fractures by targeting transforming growth factor‑β1

Pengfei Zhao, Shaochun Wang, Yingjie Zhou, Huailiang Zheng, Gang Zhao
Pages: 1127-1132
Published online on: 17 January 2017

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Article

Association of nNOS and Rho‑kinase with age‑associated erectile dysfunction in Sprague‑Dawley rats

Zhibo Ding, Xingjie Shen, Yunfei Li
Pages: 1133-1136
Published online on: 19 January 2017

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Article

Downregulation of a novel long non‑coding RNA, LOC389332, is associated with poor prognosis and tumor progression in clear cell renal cell carcinoma

Ping Jin, Juan Wang, Yu Liu
Pages: 1137-1142
Published online on: 24 January 2017

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Article

α- and β-Naphthoflavone synergistically attenuate H2O2-induced neuron SH-SY5Y cell damage

Yong Zhu, Fangfang Bi, Yanchun Li, Huiming Yin, Na Deng, Haiquan Pan, Dongfang Li, Bo Xiao
Pages: 1143-1150
Published online on: 13 January 2017

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Case Report

VanWyk‑Grumbach syndrome in a male pediatric patient: A rare case report and literature review

Shanshan Zhang, Jingyan Yang, Rongxiu Zheng, Lihong Jiang, Ying Wei, Geli Liu
Pages: 1151-1154
Published online on: 24 January 2017

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Article

Iodine‑131 therapy alters the immune/inflammatory responses in the thyroids of patients with Graves' disease

Wenhua Du, Qingyu Dong, Xiaoting Lu, Xiaomeng Liu, Yueli Wang, Wenxia Li, Zhenyu Pan, Qian Gong, Cuige Liang, Guanqi Gao
Pages: 1155-1159
Published online on: 16 January 2017

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Article

Upregulation of OLR1 and IL17A genes and their association with blood glucose and lipid levels in femoropopliteal artery disease

Caner Arslan, Burcu Bayoglu, Cigdem Tel, Mujgan Cengiz, Ahmet Dirican, Kazim Besirli
Pages: 1160-1168
Published online on: 24 January 2017

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Article

Changes in liver stiffness and its associated factors during oral antiviral therapy in Chinese patients with chronic hepatitis B

Xu Li, Qinglong Jin, Hong Zhang, Xue Jing, Zhongyang Ding, Hongjie Zhou, Zetian Zhang, Dongqing Yan, Dongmei Li, Pujun Gao, Junqi Niu
Pages: 1169-1175
Published online on: 19 January 2017

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Article

Feasibility of improving platelet‑rich plasma therapy by using chitosan with high platelet activation ability

Hidemi Hattori, Masayuki Ishihara
Pages: 1176-1180
Published online on: 13 January 2017

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Journal Cover
October-2026 Volume 32 Issue 4

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Impact Factor: 2.2

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Promoting expertise knowledge sharing in paediatric virology: An update (Review)

Ioannis N. Mammas, Anna Kramvis, Anastasia Stouraiti, Tina Dalianis, Patra Koletsi, Georgia Papaioannou, Alexia Papatheodoropoulou, Chryssie Koutsaftiki, Paraskevi Korovessi, Simon B. Drysdale, Maria Theodoridou, Demetrios A. Spandidos
Article Number: 293
Published online on: 07 September 2026

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ACT001 suppresses ox‑LDL‑mediated macrophage ferroptosis via activating the NRF2 pathway: An in vitro mechanistic study relevant to atherosclerosis

Yangyang Tao, Yuwu Chen, Yonghou Zhao, Jianbo Cai
Article Number: 292
Published online on: 07 September 2026

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From mitochondria to innate immunity: The mtDNA‑driven cGAS/STING‑NLRP3 cascade and its therapeutic implications in neurodegenerative diseases (Review)

Hui Liu, Yao Zhang, Ziliang Zhuo, Wei Zhong, Manyun Yan, Zhongbo Zhao
Article Number: 291
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Active abdominal compression‑decompression cardiopulmonary resuscitation attenuates neuroinflammation associated with TLR4/NF‑κB signaling in a rat model of cardiac arrest

Xiaopeng Liu, Xiaoqing Yang, Yifan Huang, Xinyuan Kong, Jiankai Gao, Hongyu Wang, Sisen Zhang
Article Number: 290
Published online on: 04 September 2026

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Review Open Access

ASF1A: A versatile histone chaperone bridging chromatin dynamics, disease mechanisms and clinical potential (Review)

Jun Yin, Xiaojian Zhuo, Lihui Wen, Xianmin Wang, Tongyong Luo, Qingsong Wang
Article Number: 289
Published online on: 02 September 2026

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Preventive administration of verapamil attenuates dextran sulfate sodium‑induced colitis in mice

Natsuki Ota, Keisuke Sato, Ryosuke Tatsunami
Article Number: 288
Published online on: 02 September 2026

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Gut microbiome dynamics in acute infectious diarrhea: A conceptual framework from acute dysbiosis toward precision restoration (Review)

Cong Yuan, Jiale Tong, Weiwei Qian, Qian He
Article Number: 287
Published online on: 02 September 2026

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Mapping and anatomo‑surgical techniques for language preservation in brain tumours (Review)

Xiaoyuan Liu, Jia Ouyang, Jiangfei Wang
Article Number: 286
Published online on: 02 September 2026

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Correction Open Access

[Corrigendum] Circular RNA expression profiles significantly altered in UVA‑irradiated human dermal fibroblasts

Mengbi Lin, Yue Zheng, Qian Li, Yufang Liu, Qingfang Xu, Yuying Li, Wei Lai
Article Number: 285
Published online on: 01 September 2026

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Generation and evaluation of multimers of anti C‑reactive protein Nb and alkaline phosphatase based on three self‑assembly peptides

Honghe Li, Chenchen Zhou, Xiaomei Zhang, Ning Ding, Qiong Wu, Junming Li, Yang Zheng, Xuejun Hu
Article Number: 284
Published online on: 28 August 2026

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New insights into diagnostic values and mechanisms of ferroptosis associated with immune infiltration in diabetic kidney disease

Ying Tan, Zihui Liu, Siyuan Song, Lingling Zhu, Yun She, Xiqiao Zhou, Jiangyi Yu, Qianhua Yan
Article Number: 283
Published online on: 28 August 2026

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Review Open Access

Biological mechanisms underlying the effects of low‑magnitude mechanical stress in osteoporosis (Review)

Zhi Liu, Dan Han, Yanfei Wang, Hongfan Li, Xuedong Pei, Zhijing Song
Article Number: 282
Published online on: 28 August 2026

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Expression of Concern Open Access

[Expression of Concern] Transformation of nomifensine using ionizing radiation and exploration of its anticancer effects in MCF‑7 cells

Seong Hee Kang, Dong-Ho Bak, Byung Yeoup Chung, Hyoung-Woo Bai
Article Number: 281
Published online on: 21 August 2026

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Retrospective study of infusion‑related reactions in subcutaneous daratumumab administration in Japan

Yoko Ino, Kazuhide Tanaka, Fuka Ito, Nao Yamagishi, Futa Takemura, Masahiro Yasuda, Senji Kasahara
Article Number: 280
Published online on: 20 August 2026

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Retraction Open Access

[Retracted] Combined effects of Lenvatinib and iodine‑131 on cell apoptosis in nasopharyngeal carcinoma through inducing endoplasmic reticulum stress

Guoyu Wang, Juhua Zhuang, Jing Ni, Ying Ye, Saifei He, Wei Xiai
Article Number: 279
Published online on: 17 August 2026

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PDK1/AKT signaling is involved in the anti‑tumor effect of gramine and cisplatin chemoresistance in ovarian cancer cells

Haiyan Wang, Ruiming Zheng, Bujun Wang, Sumiao Hong, Hongxia Chen
Article Number: 278
Published online on: 14 August 2026

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Integrating clinical outcomes with molecular simulations to guide the selection of non‑classical EGFR‑TKIs: A comprehensive analysis and development of treatment strategies

Fang Wei, Niu Niu, Chang Li, Ge Gao, Nan Li, Yan Wang
Article Number: 277
Published online on: 14 August 2026

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Case Report Open Access

Clinicopathological analysis of neuroendocrine carcinoma discovered incidentally in hemorrhoids: A case report and literature review

Bin Huang, Haiyan Zhou, Jianping Shi, Hongsheng Liu
Article Number: 276
Published online on: 12 August 2026

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Mechanism of microRNA‑30b‑5p enhancing the response of MDA‑MB‑231 cells to cisplatin by regulating RAP1B expression

Kewei Tang, Site Bai, Yajun Tong, Songjiang Liu, Leilan Yin, Ludi Ou, Qinghua Yin, Qiang Zhou
Article Number: 275
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Platelet‑rich plasma shows beneficial effects for patients with knee osteoarthritis by suppressing inflammatory factors

Guilin Huang, Sha Hua, Tuanmin Yang, Jianbing Ma, Wenxing Yu, Xiujin Chen
Article Number: 274
Published online on: 12 August 2026

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Establishment of a novel asymmetric force degenerative lumbar scoliosis aging bipedal rat model

Jing Peng, Daigui Cao, Xu Zhou, Zhiwei Liu, Xinxing Wang, Anwei Zhang, Kai Shen
Article Number: 273
Published online on: 11 August 2026

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Case Report Open Access

Rapid diagnosis of Chlamydia psittaci pneumonia with pleural effusion using multiplex PCR‑based targeted next‑generation sequencing: A case report

Yang Jin, Liqun He, Jiankun Wang, Tao Ren, Hansheng Wang, Yue Wang
Article Number: 272
Published online on: 11 August 2026

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Sanguinarine chloride inducing ferroptosis and downregulating GPX4 expression in liver cancer: An integrated in silico, in vitro and in vivo study

Wen Ouyang, Jianxin Gao, Jing Liu, Lulu Qin, Bang Liu, Ying He, Dai Zhou
Article Number: 271
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Activated protein C overexpression suppresses the pyroptosis of subarachnoid hemorrhage model cells by regulating the NLRP3 inflammasome pathway

Ai Yan, Xuyan Pan, Xianqiang Wen, Xiaohu Nie, Yuntao Li
Article Number: 270
Published online on: 10 August 2026

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RPLP0 drives diffuse large B‑cell lymphoma cell proliferation through reactive oxygen species‑dependent AKT/mTOR activation and inhibition of stress‑induced autophagy

Shanshan Wang, Xutao Yang, Rochelle Mcgowan, Belinda Hodge, Daniel Shan, Nicolas Miller, Jiahong Tang
Article Number: 269
Published online on: 07 August 2026

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Baseline neutrophil‑to‑lymphocyte ratio is not associated with chemotherapy‑induced nausea and vomiting in patients with breast cancer: A single‑center retrospective cohort study

Ruhper Cekin, Akif Dogan
Article Number: 268
Published online on: 07 August 2026

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Case Report Open Access

First case of neonatal bloodstream infection caused by Malassezia furfur in mainland China diagnosed via metagenomic next‑generation sequencing: A case report

Shanshan Gao, Lanlan Song, Qiujuan Feng, Yazhen Li, Huiqiang Liang, Ke Lei, Zheng Li, Peter Kisembo
Article Number: 267
Published online on: 06 August 2026

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Article

Comparative analysis of early and late recurrence rates in perianal fistula surgery

Ahmed Taha, Hi̇kmet Haşemi̇, Mutali̇p Ertuş, Bülent Özçeti̇n
Article Number: 266
Published online on: 06 August 2026

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Case Report

Cystic lymphangioma presenting as an ovarian mass in an adolescent: A case report and literature review

Rui Sun, Chun-Run Yang
Article Number: 265
Published online on: 05 August 2026

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Case Report

Postmenopausal osseous metaplasia of the endometrium: An uncommon histopathological entity: A case report

Emmanouela Aliki Almperi, Chrysoula Margioula Siarkou, Aristarchos Almperis, Nikoleta Dimitra Savvidou, Stamatios Petousis
Article Number: 264
Published online on: 05 August 2026

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Experimental evaluation of Curcuma Longa in docetaxel‑induced systemic toxicity: Functional hepatorenal and target organ analysis

Isabella Morais Tavares Huber, Emerson Luiz Botelho Lourenço, Salviano Tramontin Bellettini, Guilherme Donadel, João Francisco Velasquez Matumoto, Sandra Marisa Pelloso, Maria Dalva De Barros Carvalho, Stéfane Lele Rossoni, Mariana Morais Tavares Colferai, Diego Ricardo Colferai, Roberto Kenji Nakamura Cuman, Leonardo Garcia Velasquez
Article Number: 263
Published online on: 04 August 2026

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Case Report Open Access

Nasopharyngeal carcinoma with inguinal lymph node metastasis: A case report

Zhibin Lin, Shiliang Li, Donghong Yang, Tongyuan Deng, Haiwen Li, Yongcun Wang
Article Number: 262
Published online on: 04 August 2026

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Case Report

Adult‑onset focal nodular non‑exophytic nesidioblastosis mimicking insulinoma detected by endoscopic ultrasonography: A case report

Mesut Pekmez, Ümit Özçelik, Kemal Yandakçi, Alper Bilal Özkardeş
Article Number: 261
Published online on: 04 August 2026

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Expression of Concern Open Access

[Expression of Concern] MicroRNA‑221 regulates cell activity and apoptosis in acute lymphoblastic leukemia via regulating PTEN

Lingyan Zhang, Zibin Bu, Juan Shen, Liping Shang, Yuanyuan Chen, Ping Zhang, Yan Wang
Article Number: 260
Published online on: 29 July 2026

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Predicting lower extremity deep vein thrombosis in elderly patients with hip fracture: A machine learning model with emphasis on diabetes as a key risk factor

Qian Song, Ping'an Shi, Peng Tian, Aijun Chao, Yinguang Zhang, Qiang Dong
Article Number: 259
Published online on: 29 July 2026

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Spatial specificity of Epstein‑Barr virus infection in gastric cancer: A 44‑case clinicopathological analysis

Xuming Wang, Longkuan Xu, Xiaozhen Yang, Xiaolu Yuan, Houliang Lu, Qiong Liu, Lijiang Liu
Article Number: 258
Published online on: 29 July 2026

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Article Open Access

Crocin I delays cellular senescence potentially via modulating SIRT1/PKM2 expression to improve lactate homeostasis in vitro

Yicheng Fu, Zhiwei Ding, Yunchuang Chang, Chunxia Wu, Sanying Wang, Genxiang Mao, Huili Su
Article Number: 257
Published online on: 29 July 2026

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Case Report

Immune‑mediated liver injury caused by checkpoint inhibitors: A case series and review of the literature

Maria Kyrkasiadou, Anastasios Kyriazoglou, Ioannis Kotsantis, Panagiota Economopoulou, George Kavourakis, Roubini Zakopoulou, Maria Anastasiou, Anastasios Pantazopoulos, Anna Boulouta, Myrto Moutafi, Niki Gavrielatou, Periklis Foukas, Menelaos Samaras, Konstantinos Palialexis, Amanda Psyrri
Article Number: 256
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Reduced expression levels of the death‑associated protein kinase and E‑cadherin are correlated with the development of esophageal squamous cell carcinoma

Jianwen Zhai, Xiaogang Yang, Yanli Zhang, Qingbin Qi, Jigang Hu, Qiaomei Wang
Article Number: 255
Published online on: 27 July 2026

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Hematopoietic cell‑specific knockout Hspa9 impairs natural killer cell function and alters the Akt/mTOR axis in mice

Xiaokang Zeng, Jieyu Zhang, Caiying Liang, Jie Yao, Zuqiang Wu
Article Number: 254
Published online on: 24 July 2026

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Comparative study on mouse models of acute exacerbation of pulmonary fibrosis

Xu Ye, Mingrui Zhang, Mengying Liu, Huihui Zhu, Xiaoling Ye, Cheng Jiang, Qi Li, Xinmei Huang, Mengshu Cao
Article Number: 253
Published online on: 24 July 2026

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Correction Open Access

[Corrigendum] TBL1XR1 as a potential therapeutic target that promotes epithelial‑mesenchymal transition in lung squamous cell carcinoma

Yuehua Zhao, Hao Lin, Jingwei Jiang, Mengxi Ge, Xiaohua Liang
Article Number: 252
Published online on: 23 July 2026

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November-2026 Volume 32 Issue 5

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Review Open Access

Advances in drug prevention and treatment of radiation‑induced lung injury (Review)

Shuo Liu, Minting Ma, Chanjun Zhen, Yang Zhao, Yuzhi Song, Qiuying An, Zhiguo Zhou, Wenwen Bai
Article Number: 323
Published online on: 29 September 2026

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Effects of PD‑1/PD‑L1 on the malignant behavior of thyroid cancer cells through the TGF‑β/Smad signaling pathway

Xueji Wang, Jing Wang, Wei Cui, Jingxia Wang, Xueyan Zhang, Bingliang Zhang
Article Number: 322
Published online on: 29 September 2026

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Assessment of muscularis propria invasion in urothelial bladder carcinoma using continuous‑time random walk and stretched‑exponential models: Comparison with VI‑RADS and apparent diffusion coefficient

Yangying Wu, Xiaofang Zhu, Xiaolong Zhou, Canli Liu, Li Guo, Jingang Hao, Yunyun Shang
Article Number: 321
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin suppresses TNF‑α‑induced inflammatory injury and senescence of nucleus pulposus cells via the Sirt6/NF‑κB pathway

Tian Xie, Jun Yuan, Ling Mei, Ping Li, Ruijie Pan
Article Number: 320
Published online on: 29 September 2026

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Tislelizumab‑induced psoriasis in a patient with hepatocellular carcinoma: A case report

Zhaochen Sun, Yuqi Zhou, Yeliang Mei, Yitian Chen
Article Number: 319
Published online on: 23 September 2026

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Functional heterogeneity of exosomes in hepatocellular carcinoma (Review)

Shiyan He, Xia Wu, Zhihao Wang, Xiong Zeng, Jing Lin, Jie Wang
Article Number: 318
Published online on: 23 September 2026

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Transforming growth factor β‑activated kinase 1 as a central integrator of immune‑microbiota crosstalk in colitis (Review)

Haoyu Dong, Sirui Wang, Ridong Lai, Guofeng Li
Article Number: 317
Published online on: 23 September 2026

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Integrated bioinformatics and clinical validation of oxidative stress‑associated genes in atrial fibrillation and chronic kidney disease

Jiyi Liu, Zezhou Xie, Huimin Yu, Fengzhi Sun, Ruifeng Wang, Yunbo Ba, Hao Huang, Xiaomeng Yin, Yu Wang
Article Number: 316
Published online on: 23 September 2026

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Case Report Open Access

Pulmonary tuberculosis occurring during the diagnosis and treatment of sarcoidosis complicated by chylothorax: A case report 

Huai-Jie Wang, Xue Li, Wen-Ge Han, Yuan-Yuan Tang, Yan-Yan Zhang, Yu-Bing Wang, Yong Zhang, Xiao-Qi Zhang, Mei-Hua Qu
Article Number: 315
Published online on: 23 September 2026

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[Retracted] Knockdown of lncRNA CCEPR suppresses colorectal cancer progression

Yuxia Duan, Zhixue Fang, Zeya Shi, Ling Zhang
Article Number: 314
Published online on: 22 September 2026

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Prognostic significance of the blood urea nitrogen‑to‑serum albumin ratio in patients with septic shock

Jianhua Liu, Zhengxiang Wei, Sheng Ye, Min Shao
Article Number: 313
Published online on: 21 September 2026

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Endometrial thickness and cancer risk in asymptomatic postmenopausal women: Defining evidence‑based cut‑offs by systematic review and diagnostic meta‑analysis

Yan Song, Hongying Wu, Ting Qin, Nana Li, Meng Wang
Article Number: 312
Published online on: 21 September 2026

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Case Report Open Access

Neurosyphilis presenting as status epilepticus and hemiplegia diagnosed by metagenomic next-generation sequencing: A case report

Hongshan Chu, Shibo Dong, Yuan Zhang, Ruisheng Duan, Ling Li
Article Number: 311
Published online on: 21 September 2026

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Case Report

BBS10‑related Bardet‑Biedl syndrome with an atypical presentation of diabetes mellitus: A case report

Lei Zhang, Guoliang Li, Hong Chang, Yanhui Dong, Nana Sun, Rina Wu, Likun Han
Article Number: 310
Published online on: 16 September 2026

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Development of a recombinase‑aided amplification assay for rapid and sensitive detection of Pneumocystis jirovecii infection: A single‑center molecular study

Hanhan Zhu, Ben Yang, Ke Chen, Fang Xu, Meihua Qu, Yuanyuan Tang
Article Number: 309
Published online on: 16 September 2026

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Case Report

Severe steroid‑refractory immune checkpoint inhibitor‑associated pneumonitis and exploration of potential biomarkers: A case report

Yan-Jun Xue, Ai-Zhen Xu, Xin-Da Yin, Lei Wei
Article Number: 308
Published online on: 16 September 2026

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Article

Effects of ketamine and dexmedetomidine on ischemia‑ reperfusion injury in an experimental renal ischemia model

Muhammet Hanifi Erdoğan, Hakan Kardaş, Tülay Zenginkinet, Tuğba Bingöl Tanriverdi, Melek Güra Çelik
Article Number: 307
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Ginsenoside Rg1 ameliorates apoptosis, senescence and oxidative stress in ox‑LDL‑induced vascular endothelial cells via the AMPK/SIRT3/p53 signaling pathway 

Tian-Jiao Lyu, Zi-Xiu Zhang, Jun Chen, Zong-Jun Liu
Article Number: 306
Published online on: 16 September 2026

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Review Open Access

Carrageenan‑induced immunothrombotic models in rodents (Review)

Xiaomu Ma, Daihan Wu, Simin Lv
Article Number: 305
Published online on: 16 September 2026

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Retraction Open Access

[Retracted] Role of peptidylarginine deiminase type 4 in gastric cancer 

Jiang Xin, Xiuqi Song
Article Number: 304
Published online on: 15 September 2026

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Article Open Access

Immune checkpoint inhibitor‑induced myocarditis with myositis and/or myasthenia gravis overlap syndrome: A case series

Qing Sun, Qing Liu, Jiabin Zheng, Yanni Lou, Huijuan Cui, Junyu Ma, Yu Wang, Dantao Peng, Weihe Zhang, Renbin Wang
Article Number: 303
Published online on: 14 September 2026

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Cardiovascular health metrics and the risk of metabolic dysfunction‑associated steatosis liver disease: A meta‑analysis

Gang Fan, Hong Zuo, Bo Liu
Article Number: 302
Published online on: 14 September 2026

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Multiple relapses of cryptogenic organizing pneumonia: A case report

Sheng Xu, Beibei Li, Yanmin Li, Jian Sun, Qiang Wang
Article Number: 301
Published online on: 11 September 2026

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Article Open Access

A diagnostic and classification model integrating cTnI, CK‑MB, MYO and NT‑proBNP for cardiovascular diseases

Huaxin Zhang, Jianan Wang, Qi Li, Tong Zhi, Xiandong Chang
Article Number: 300
Published online on: 11 September 2026

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Case Report Open Access

A rare suprasellar lesion with multifocal central nervous system involvement in clinically diagnosed von Hippel‑Lindau disease: A case report

Zekai Wu, Lei Zhang, Meng Tan, Laian Zhang
Article Number: 299
Published online on: 11 September 2026

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Case Report Open Access

Reversible osimertinib‑associated heart failure mimicking cancer recurrence in EGFR‑mutated non‑small cell lung cancer after pneumonectomy: A case report

Hirona Yokoyama, Nobuhito Hara, Rika Sasaki, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Takeshi Kawaguchi, Masatsugu Hamaji, Yuji Nitta, Maiko Takeda, Masayuki Takeda
Article Number: 298
Published online on: 11 September 2026

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Regenerative endodontic treatment for premolars with apical root segment separation and extensive periapical lesions secondary to severe inflammatory root resorption: A report of two cases

Qian Wu, Daniel J. Yen
Article Number: 297
Published online on: 11 September 2026

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Retraction Open Access

[Retracted] Hsp70 inducer, 17‑allylamino‑demethoxygeldanamycin, provides neuroprotection via anti‑inflammatory effects in a rat model of traumatic brain injury

Youquan Gu, Jun Chen, Tianhong Wang, Chaoning Zhou, Zhaodong Liu, Lanhua Ma
Article Number: 296
Published online on: 10 September 2026

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Case Report

Relapsed/refractory multiple myeloma with extramedullary plasmacytomas successfully rechallenged with humanized B‑cell maturation antigen‑directed chimeric antigen receptor T‑cell immunotherapy in an advanced disease stage: A case report

Runfeng Zhang, Lili Cheng, Jinghua Liu, Lu Zhang, Junling Zhuang
Article Number: 295
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] JWA regulates human esophageal squamous cell carcinoma and human esophageal cells through different mitogen‑activated protein kinase signaling pathways

Jie Lin, Tieliang Ma, Xiaodong Jiang, Zhijun Ge, Weiliang Ding, Yuanyuan Wu, Guojun Jiang, Jiake Feng, Guoxing Cui, Yongfei Tan
Article Number: 294
Published online on: 07 September 2026

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