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Raman spectrum: A potential biomarker for embryo assessment during in vitro fertilization

  • Authors:
    • Jiayi Ding
    • Tian Xu
    • Xiaofang Tan
    • Hua Jin
    • Jun Shao
    • Haibo Li
  • View Affiliations / Copyright

    Affiliations: Department of Clinical Laboratory Medicine, Nantong Maternity and Child Health Hospital, Nantong, Jiangsu 226018, P.R. China, Department of Physics, School of Science, Nantong University, Nantong, Jiangsu 226019, P.R. China
    Copyright: © Ding et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1789-1792
    |
    Published online on: February 23, 2017
       https://doi.org/10.3892/etm.2017.4160
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Abstract

The aim of the study was to investigate whether Raman spectrum is consistent with the morphological scoring of the embryo of day 3 during in vitro fertilization (IVF). The spent culture media of embryo of day 3 from 10 patients were collected and analyzed. The samples were analyzed using Raman spectroscopy and graded according to the standard embryo scoring system simultaneously. Data showed that the Raman spectra obtained from the droplet of media were useful, as they can act as the characteristic signature for protein and amino acids. The Raman biospectroscopy-based metabonomics profiling of spent media was consistent with the result of conventional morphological evaluation. In conclusion, this technology offers great potential for the development of tools allowing rapid non-invasive assessment of the quality of embryo of day 3 during IVF.
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Copy and paste a formatted citation
Spandidos Publications style
Ding J, Xu T, Tan X, Jin H, Shao J and Li H: Raman spectrum: A potential biomarker for embryo assessment during in vitro fertilization. Exp Ther Med 13: 1789-1792, 2017.
APA
Ding, J., Xu, T., Tan, X., Jin, H., Shao, J., & Li, H. (2017). Raman spectrum: A potential biomarker for embryo assessment during in vitro fertilization. Experimental and Therapeutic Medicine, 13, 1789-1792. https://doi.org/10.3892/etm.2017.4160
MLA
Ding, J., Xu, T., Tan, X., Jin, H., Shao, J., Li, H."Raman spectrum: A potential biomarker for embryo assessment during in vitro fertilization". Experimental and Therapeutic Medicine 13.5 (2017): 1789-1792.
Chicago
Ding, J., Xu, T., Tan, X., Jin, H., Shao, J., Li, H."Raman spectrum: A potential biomarker for embryo assessment during in vitro fertilization". Experimental and Therapeutic Medicine 13, no. 5 (2017): 1789-1792. https://doi.org/10.3892/etm.2017.4160
Copy and paste a formatted citation
x
Spandidos Publications style
Ding J, Xu T, Tan X, Jin H, Shao J and Li H: Raman spectrum: A potential biomarker for embryo assessment during in vitro fertilization. Exp Ther Med 13: 1789-1792, 2017.
APA
Ding, J., Xu, T., Tan, X., Jin, H., Shao, J., & Li, H. (2017). Raman spectrum: A potential biomarker for embryo assessment during in vitro fertilization. Experimental and Therapeutic Medicine, 13, 1789-1792. https://doi.org/10.3892/etm.2017.4160
MLA
Ding, J., Xu, T., Tan, X., Jin, H., Shao, J., Li, H."Raman spectrum: A potential biomarker for embryo assessment during in vitro fertilization". Experimental and Therapeutic Medicine 13.5 (2017): 1789-1792.
Chicago
Ding, J., Xu, T., Tan, X., Jin, H., Shao, J., Li, H."Raman spectrum: A potential biomarker for embryo assessment during in vitro fertilization". Experimental and Therapeutic Medicine 13, no. 5 (2017): 1789-1792. https://doi.org/10.3892/etm.2017.4160
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