Successful treatment of diffuse panbronchiolitis in a child from Western China: A case report

Zhao,Na‑Na; Cao,Hui; Zhang,Shi‑Si; Cao,Guo‑Qiang

doi:10.3892/etm.2017.4196

May-2017 Volume 13 Issue 5

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May-2017 Volume 13 Issue 5

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Case Report

Successful treatment of diffuse panbronchiolitis in a child from Western China: A case report

Authors:
- Na‑Na Zhao
- Hui Cao
- Shi‑Si Zhang
- Guo‑Qiang Cao
View Affiliations / Copyright

Affiliations: Department of Respiratory Medicine, Institute of Surgery Research, The Third Affiliated Hospital, The Third Military Medical University, Chongqing 400042, P.R. China, Department of Radiology, Institute of Surgery Research, The Third Affiliated Hospital, The Third Military Medical University, Chongqing 400042, P.R. China
Pages: 2094-2096
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Published online on: March 8, 2017

https://doi.org/10.3892/etm.2017.4196
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Abstract

The present report describes a case of diffuse panbronchiolitis (DPB) in a child from Western China and the favorable outcome associated with early diagnosis. DPB is an uncommon presentation in pediatric patients. A 13-year-old Chinese boy was admitted to the respiratory outpatient department due to recurrent cough and progressive exertional dyspnea that had persisted for 1 year. An initial diagnosis of bronchial asthma was made, and the patient was prescribed inhaled fluticasone combined with salmeterol (50/250 µg, twice daily), and montelukast (4 mg daily). However, 2 months later no clinical improvement was observed. The disease was re‑diagnosed as DPB following the identification of features such as centrilobular small nodular opacities, a ‘tree‑in‑bud appearance’ and thickening of the bronchial walls meeting the diagnostic criteria for DPB. Complete resolution of the disease and sustained alleviation of the patient's respiratory symptoms were achieved following the early institution of erythromycin therapy, and the exacerbation of chronic bronchitis was reduced. In conclusion, it is essential to consider that successful treatment for DPB lies in early diagnosis and early treatment. DPB may be treated well by use of erythromycin.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Successful treatment of diffuse panbronchiolitis in a child from Western China: A case report

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Abstract

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