|
1
|
World Health Organization (WHO): Global
tuberculosis control: Surveillance, planning, financing: WHO report
2008. WHO; Geneva: 2008
|
|
2
|
Skeiky YA and Sadoff JC: Advances in
tuberculosis vaccine strategies. Nat Rev Microbiol. 4:469–476.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Murray PJ, Aldovini A and Young RA:
Manipulation and potentiation of antimycobacterial immunity using
recombinant bacille Calmette-Guérin strains that secrete cytokines.
Proc Natl Acad Sci USA. 93:934–939. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
O'Donnell MA, Aldovini A, Duda RB, Yang H,
Szilvasi A, Young RA and DeWolf WC: Recombinant Mycobacterium
bovis BCG secreting functional interleukin-2 enhances gamma
interferon production by splenocytes. Infect Immun. 62:2508–2514.
1994.PubMed/NCBI
|
|
5
|
Luo Y, Yamada H, Chen X, Ryan AA, Evanoff
DP, Triccas JA and O'Donnell MA: Recombinant Mycobacterium
bovis bacillus Calmette-Guérin (BCG) expressing mouse IL-18
augments Th1 immunity and macrophage cytotoxicity. Clin Exp
Immunol. 137:24–34. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Flynn JL and Chan J: Immunology of
tuberculosis. Annu Rev Immunol. 19:93–129. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Eddine Nasser A and Kaufmann SH: Improved
protection by recombinant BCG. Microbes Infect. 7:939–946. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Agger EM and Andersen P: Tuberculosis
subunit vaccine development: On the role of interferon-γ. Vaccine.
19:2298–2302. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
D'Souza S, Rosseels V, Romano M, Tanghe A,
Denis O, Jurion F, Castiglione N, Vanonckelen A, Palfliet K and
Huygen K: Mapping of murine Th1 helper T-Cell epitopes of mycolyl
transferases Ag85A, Ag85B, and Ag85C from Mycobacterium
tuberculosis. Infect Immun. 71:483–493. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Horwitz MA and Harth G: A new vaccine
against tuberculosis affords greater survival after challenge than
the current vaccine in the guinea pig model of pulmonary
tuberculosis. Infect Immun. 71:1672–1679. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Horwitz MA, Harth G, Dillon BJ and
Maslesa-Galic' S: Recombinant bacillus calmette-guerin (BCG)
vaccines expressing the Mycobacterium tuberculosis 30-kDa
major secretory protein induce greater protective immunity against
tuberculosis than conventional BCG vaccines in a highly susceptible
animal model. Proc Natl Acad Sci USA. 97:13853–13858. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Horwitz MA: Recombinant BCG expressing
Mycobacterium tuberculosis major extracellular proteins.
Microbes Infect. 7:947–954. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Hoft DF, Blazevic A, Abate G, Hanekom WA,
Kaplan G, Soler JH, Weichold F, Geiter L, Sadoff JC and Horwitz MA:
A new recombinant bacille Calmette-Guérin vaccine safely induces
significantly enhanced tuberculosis-specific immunity in human
volunteers. J Infect Dis. 198:1491–1501. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Xu Y, Liu W, Shen H, Yan J, Qu D and Wang
H: Recombinant Mycobacterium bovis BCG expressing the
chimeric protein of antigen 85B and ESAT-6 enhances the Th1
cell-mediated response. Clin Vaccine Immunol. 16:1121–1126. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Forbes EK, Sander C, Ronan EO, McShane H,
Hill AV, Beverley PC and Tchilian EZ: Multifunctional, high-level
cytokine-producing Th1 cells in the lung, but not spleen, correlate
with protection against Mycobacterium tuberculosis aerosol
challenge in mice. J Immunol. 181:4955–4964. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Xu Y, Zhu B, Wang Q, Chen J, Qie Y, Wang J
and Wang H, Wang B and Wang H: Recombinant BCG coexpressing Ag85B,
ESAT-6 and mouse-IFN-γ confers effective protection against
Mycobacterium tuberculosis in C57BL/6 mice. FEMS Immunol Med
Microbiol. 51:480–487. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Moreira AL, Tsenova L, Murray PJ, Freeman
S, Bergtold A, Chiriboga L and Kaplan G: Aerosol infection of mice
with recombinant BCG secreting murine IFN-γ partially reconstitutes
local protective immunity. Microb Pathog. 29:175–185. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Yi Z, Fu Y, Yang C, Li J, Luo X, Chen Q,
Zeng W, Jiang S, Jiang Y, He Y, et al: Recombinant M.
smegmatis vaccine targeted delivering IL-12/GLS into
macrophages can induce specific cellular immunity against M.
tuberculosis in BALB/c mice. Vaccine. 25:638–648. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Martin RM and Lew AM: Is IgG2a a good Th1
marker in mice? Immunol Today. 19:491998. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Luo Y, Chen X, Han R and O'Donnell MA:
Recombinant bacille Calmette-Guérin (BCG) expressing human
interferon-alpha 2B demonstrates enhanced immunogenicity. Clin Exp
Immunol. 123:264–270. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Wangoo A, Brown IN, Marshall BG, Cook HT,
Young DB and Shaw RJ: Bacille Calmette-Guérin (BCG)-associated
inflammation and fibrosis: Modulation by recombinant BCG expressing
interferon-γ (IFN-γ). Clin Exp Immunol. 119:92–98. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wong P and Pamer EG: CD8 T cell responses
to infectious pathogens. Annu Rev Immunol. 21:29–70. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Cooper AM, Adams LB, Dalton DK, Appelberg
R and Ehlers S: IFN-γ and NO in mycobacterial disease: New jobs for
old hands. Trends Microbiol. 10:221–226. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Rook GA, Seah G and Ustianowski A: M.
tuberculosis: Immunology and vaccination. Eur Respir J.
17:537–557. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Feng Y, Yang X, Liu Z, Liu Y, Su B, Ding
Y, Qin L, Yang H, Zheng R and Hu Z: Continuous treatment with
recombinant Mycobacterium tuberculosis CFP-10-ESAT-6 protein
activated human monocyte while deactivated LPS-stimulated
macrophage. Biochem Biophys Res Commun. 365:534–540. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Bhatt K, Uzelac A, Mathur S, McBride A,
Potian J and Salgame P: B7 costimulation is critical for host
control of chronic Mycobacterium tuberculosis infection. J
Immunol. 182:3793–3800. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Kan-Sutton C, Jagannath C and Hunter RL
Jr: Trehalose 6,6′-dimycolate on the surface of Mycobacterium
tuberculosis modulates surface marker expression for antigen
presentation and costimulation in murine macrophages. Microbes
Infect. 11:40–48. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Seder RA, Darrah PA and Roederer M: T-cell
quality in memory and protection: Implications for vaccine design.
Nat Rev Immunol. 8:247–258. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Lindenstrøm T, Agger EM, Korsholm KS,
Darrah PA, Aagaard C, Seder RA, Rosenkrands I and Andersen P:
Tuberculosis subunit vaccination provides long-term protective
immunity characterized by multifunctional CD4 memory T cells. J
Immunol. 182:8047–8055. 2009. View Article : Google Scholar : PubMed/NCBI
|
