Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
August-2017 Volume 14 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
August-2017 Volume 14 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Diffusion-weighted imaging of injuries to the visual centers of the brain in patients with type 2 diabetes and retinopathy

  • Authors:
    • Ming Liang
    • Xing Chen
    • Feng Xue
    • Lingna Meng
    • Yunfeng Cong
  • View Affiliations / Copyright

    Affiliations: Urgent Care Centre, Nangang Branch, Heilongjiang Provincial Hospital, Harbin, Heilongjiang 150001, P.R. China, Department of Internal Medical Oncology, Nangang Branch, Heilongjiang Provincial Hospital, Harbin, Heilongjiang 150001, P.R. China, Department of Stomatology, Nangang Branch, Heilongjiang Provincial Hospital, Harbin, Heilongjiang 150001, P.R. China
  • Pages: 1153-1156
    |
    Published online on: June 12, 2017
       https://doi.org/10.3892/etm.2017.4582
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The present study aimed to investigate the ability of diffusion-weighted imaging (DWI) to identify injury to the visual centers of the brain in patients with type 2 diabetes with retinopathy. The study included 84 cases (63 patients with type 2 diabetic retinopathy and 21 healthy individuals) that were assessed using DWI. Diabetic patients were equally divided into three groups: Proliferative diabetic retinopathy (PDR), non‑proliferative diabetic retinopathy (NPDR) and diabetic without retinopathy. The results demonstrated that individuals in the PDR group had significantly higher disease duration and glycated hemoglobin levels than the diabetic without retinopathy group (P<0.05). Apparent diffusion coefficient (ADC) values were significantly higher in functional brain areas of the PDR group compared with the NPDR group (P<0.001), whose values were significantly higher compared with the diabetic without retinopathy and control groups (P<0.001). In addition, glycated hemoglobin levels and disease duration were positively correlated with mean ADC values in the same functional areas of the brain. In conclusion, DWI‑measured ADC values may be an effective indicator of brain dysfunction in individuals with type 2 diabetic retinopathy. DWI is able to assess brain injury in individuals with early diabetic retinopathy, which may make the diagnostic technique a useful predictor of early ocular disease.
View Figures

Figure 1

Figure 2

View References

1 

Sivaprasad S, Gupta B, Crosby-Nwaobi R and Evans J: Prevalence of diabetic retinopathy in various ethnic groups: A worldwide perspective. Sur Ophthalmol. 57:347–370. 2012. View Article : Google Scholar

2 

Liu L, Wu X, Liu L, Geng J, Yuan Z, Shan Z and Chen L: Prevalence of diabetic retinopathy in mainland China: A meta-analysis. PLoS One. 7:e452642012. View Article : Google Scholar : PubMed/NCBI

3 

Xu J, Xu L, Wang YX, You QS, Jonas JB and Wei WB: Ten-year cumulative incidence of diabetic retinopathy. The Beijing Eye Study 2001/2011. PLoS One. 9:e1113202014. View Article : Google Scholar : PubMed/NCBI

4 

Liu L and Chen L: Awareness of diabetic retinopathy is the key step for early prevention, diagnosis and treatment of this disease in China. Patient Educ Couns. 94:284–285. 2014. View Article : Google Scholar : PubMed/NCBI

5 

Rangarajan K, Das CJ, Kumar A and Gupta AK: MRI in central nervous system infections: A simplified patterned approach. World J Radiol. 6:716–725. 2014. View Article : Google Scholar : PubMed/NCBI

6 

Mars RB, Jbabdi S, Sallet J, O'Reilly JX, Croxson PL, Olivier E, Noonan MP, Bergmann C, Mitchell AS, Baxter MG, et al: Diffusion-weighted imaging tractography-based parcellation of the human parietal cortex and comparison with human and macaque resting-state functional connectivity. J Neurosci. 31:4087–4100. 2011. View Article : Google Scholar : PubMed/NCBI

7 

Taouli B: Diffusion-weighted MR imaging for liver lesion characterization: A critical look. Radiology. 262:378–380. 2012. View Article : Google Scholar : PubMed/NCBI

8 

Vargas HA, Akin O, Franiel T, Mazaheri Y, Zheng J, Moskowitz C, Udo K, Eastham J and Hricak H: Diffusion-weighted endorectal MR imaging at 3 T for prostate cancer: Tumor detection and assessment of aggressiveness. Radiology. 259:775–784. 2011. View Article : Google Scholar : PubMed/NCBI

9 

Shakir A, Aksoy D, Mlynash M, Harris OA, Albers GW and Hirsch KG: Prognostic value of quantitative diffusion-weighted MRI in patients with traumatic brain injury. J Neuroimaging. 26:103–108. 2016. View Article : Google Scholar : PubMed/NCBI

10 

Dogan M, Ozsoy E, Doganay S, Burulday V, Firat PG, Ozer A and Alkan A: Brain diffusion-weighted imaging in diabetic patients with retinopathy. Eur Rev Med Pharmacol Sci. 16:126–131. 2012.PubMed/NCBI

11 

Buysschaert M, Medina JL, Buysschaert B and Bergman M: Definitions (and current controversies) of diabetes and prediabetes. Curr Diabetes Rev. 12:8–13. 2016. View Article : Google Scholar : PubMed/NCBI

12 

Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Kirkman MS, Lernmark A, Metzger BE and Nathan DM; National Academy of Clinical Biochemistry; Evidence-Based Laboratory Medicine Committee of the American Association for Clinical Chemistry, : Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Diabetes Care. 34:e61–e99. 2011. View Article : Google Scholar : PubMed/NCBI

13 

Hajar S, Al Hazmi A, Wasli M, Mousa A and Rabiu M: Prevalence and causes of blindness and diabetic retinopathy in Southern Saudi Arabia. Saudi Med J. 36:449–455. 2015. View Article : Google Scholar : PubMed/NCBI

14 

Glaser NS, Marcin JP, Wootton-Gorges SL, Buonocore MH, Rewers A, Strain J, DiCarlo J, Neely EK, Barnes P and Kuppermann N: Correlation of clinical and biochemical findings with diabetic ketoacidosis-related cerebral edema in children using magnetic resonance diffusion-weighted imaging. J Pediatr. 153:541–546. 2008. View Article : Google Scholar : PubMed/NCBI

15 

Rock JP, Scarpace L, Hearshen D, Gutierrez J, Fisher JL, Rosenblum M and Mikkelsen T: Associations among magnetic resonance spectroscopy, apparent diffusion coefficients, and image-guided histopathology with special attention to radiation necrosis. Neurosurgery. 54:1111–1119. 2004. View Article : Google Scholar : PubMed/NCBI

16 

Löwel S and Engelmann R: Neuroanatomical and neurophysiological consequences of strabismus: Changes in the structural and functional organization of the primary visual cortex in cats with alternating fixation and strabismic amblyopia. Strabismus. 10:95–105. 2002. View Article : Google Scholar : PubMed/NCBI

17 

Nakagami T, Takahashi K, Suto C, Oya J, Tanaka Y, Kurita M, Isago C, Hasegawa Y, Ito A and Uchigata Y: Diabetes diagnostic thresholds of the glycated hemoglobin A1c and fasting plasma glucose levels considering the 5-year incidence of retinopathy. Diabetes Res Clin Pract. 124:20–29. 2017. View Article : Google Scholar : PubMed/NCBI

18 

Ishii A, Takemoto M, Iida S and Kanatsuka A: Abdominal induration caused by repeated same site insulin injections is related to the HbAlc level and diurnal fasting blood glucose variation in type 2 diabetics. J Japan Diab Soc. 58:94–99. 2015.

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Liang M, Chen X, Xue F, Meng L and Cong Y: Diffusion-weighted imaging of injuries to the visual centers of the brain in patients with type 2 diabetes and retinopathy. Exp Ther Med 14: 1153-1156, 2017.
APA
Liang, M., Chen, X., Xue, F., Meng, L., & Cong, Y. (2017). Diffusion-weighted imaging of injuries to the visual centers of the brain in patients with type 2 diabetes and retinopathy. Experimental and Therapeutic Medicine, 14, 1153-1156. https://doi.org/10.3892/etm.2017.4582
MLA
Liang, M., Chen, X., Xue, F., Meng, L., Cong, Y."Diffusion-weighted imaging of injuries to the visual centers of the brain in patients with type 2 diabetes and retinopathy". Experimental and Therapeutic Medicine 14.2 (2017): 1153-1156.
Chicago
Liang, M., Chen, X., Xue, F., Meng, L., Cong, Y."Diffusion-weighted imaging of injuries to the visual centers of the brain in patients with type 2 diabetes and retinopathy". Experimental and Therapeutic Medicine 14, no. 2 (2017): 1153-1156. https://doi.org/10.3892/etm.2017.4582
Copy and paste a formatted citation
x
Spandidos Publications style
Liang M, Chen X, Xue F, Meng L and Cong Y: Diffusion-weighted imaging of injuries to the visual centers of the brain in patients with type 2 diabetes and retinopathy. Exp Ther Med 14: 1153-1156, 2017.
APA
Liang, M., Chen, X., Xue, F., Meng, L., & Cong, Y. (2017). Diffusion-weighted imaging of injuries to the visual centers of the brain in patients with type 2 diabetes and retinopathy. Experimental and Therapeutic Medicine, 14, 1153-1156. https://doi.org/10.3892/etm.2017.4582
MLA
Liang, M., Chen, X., Xue, F., Meng, L., Cong, Y."Diffusion-weighted imaging of injuries to the visual centers of the brain in patients with type 2 diabetes and retinopathy". Experimental and Therapeutic Medicine 14.2 (2017): 1153-1156.
Chicago
Liang, M., Chen, X., Xue, F., Meng, L., Cong, Y."Diffusion-weighted imaging of injuries to the visual centers of the brain in patients with type 2 diabetes and retinopathy". Experimental and Therapeutic Medicine 14, no. 2 (2017): 1153-1156. https://doi.org/10.3892/etm.2017.4582
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team