Kidney dysfunction following adrenalectomy in autosomal dominant polycystic kidney disease complicated with primary aldosteronism: A case report

  • Authors:
    • Hiroyuki Hirai
    • Makoto Kanno
    • Tsuyoshi Watanabe
    • Hiroaki Satoh
  • View Affiliations

  • Published online on: June 13, 2017     https://doi.org/10.3892/etm.2017.4588
  • Pages: 1235-1240
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Abstract

The present study reported a case of autosomal dominant polycystic kidney disease complicated with primary aldosteronism in a 49‑year‑old woman. The patient was referred for refractory hypertension. Laboratory examinations revealed low potassium and renin levels. Computed tomography indicated a right adrenal tumor and multiple renal cysts. Adrenal vein sampling revealed a high aldosterone level on the side of the tumor. The patient was diagnosed with autosomal dominant polycystic kidney disease complicated by primary aldosteronism and adrenalectomy was performed. Over the following 7 months, the estimated glomerular filtration rate decreased from 76 to 48 ml/min/1.73 m2, which was attributed to glomerular hyperfiltration correction induced by hyperaldosteronism remission, indicating kidney dysfunction. Clinicians must therefore monitor for the unmasking of kidney dysfunction following adrenalectomy in such cases.
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August 2017
Volume 14 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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APA
Hirai, H., Kanno, M., Watanabe, T., & Satoh, H. (2017). Kidney dysfunction following adrenalectomy in autosomal dominant polycystic kidney disease complicated with primary aldosteronism: A case report. Experimental and Therapeutic Medicine, 14, 1235-1240. https://doi.org/10.3892/etm.2017.4588
MLA
Hirai, H., Kanno, M., Watanabe, T., Satoh, H."Kidney dysfunction following adrenalectomy in autosomal dominant polycystic kidney disease complicated with primary aldosteronism: A case report". Experimental and Therapeutic Medicine 14.2 (2017): 1235-1240.
Chicago
Hirai, H., Kanno, M., Watanabe, T., Satoh, H."Kidney dysfunction following adrenalectomy in autosomal dominant polycystic kidney disease complicated with primary aldosteronism: A case report". Experimental and Therapeutic Medicine 14, no. 2 (2017): 1235-1240. https://doi.org/10.3892/etm.2017.4588