Benefits of urethroplasty for managing urethral amyloidosis: A case report
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- Published online on: August 21, 2017 https://doi.org/10.3892/etm.2017.4983
- Pages: 3519-3522
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Copyright: © Yao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
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Abstract
Urethral amyloidosis is a rare condition in which eosinophilic amyloid proteins are deposited in the urethra. Only a small number of reports on urethral amyloidosis have been published. Increased interest has been associated with this disease due to its clinical similarities with urothelial carcinoma. A biopsy of the lesion and a histological examination are essential for the correct diagnosis. Conservative management has been suggested by various urologists as the optimal treatment approach for urethral amyloidosis; however, recurrence and urethral stricture are common, and typically further treatment is required. Urethroplasty has been used in a limited number of urethral amyloidosis cases, with beneficial short‑term outcomes; however, long‑term follow‑up data are lacking. The present case report describes the cases of 2 patients with urethral amyloidosis who underwent urethroplasty without recurrence or progression for >2 years. These findings indicate that urethroplasty is beneficial for the long‑term management of urethral amyloidosis.