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Article

Predictive factors of pancreatic necrosectomy following percutaneous catheter drainage as a primary treatment of patients with infected necrotizing pancreatitis

  • Authors:
    • Xi Cao
    • Feng Cao
    • Ang Li
    • Xiang Gao
    • Xiao‑Hui Wang
    • Dian‑Gang Liu
    • Yu Fang
    • Dong‑Hai Guo
    • Fei Li
  • View Affiliations / Copyright

    Affiliations: Department of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, P.R. China, Department of General Surgery, Ordos Central Hospital, Ordos, Inner Mongolia 017000, P.R. China
  • Pages: 4397-4404
    |
    Published online on: September 5, 2017
       https://doi.org/10.3892/etm.2017.5107
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Abstract

Pancreatic necrosectomy (PN) following percutaneous catheter drainage (PCD) is an effective method of treating patients with necrotizing pancreatitis, however, the predictive factors for PN after PCD have not yet been identified. A total of 74 patients with suspected infected necrotizing pancreatitis (INP) and peripancreatic fluid collection were enrolled in the current study between October 2010 and October 2015. These patients received ultrasound or computer topography guided PCD followed by PN. Patients were divided into two groups: i) A PCD‑alone group (n=32) and ii) a PCD+necrosectomy group (n=42). Multivariate analysis revealed that reduction of fluid collection after PCD (P=0.021), maximum extent of peripancreatic necrosis (P=0.019) and multiple organ failure (P=0.017) were predictors of PN following PCD. A prediction model was produced to evaluate the aforementioned factors and indicated that the area under the receiver operating characteristic curve was 0.827. The probability of successful PCD was determined using a prognostic nomogram. Thus, the results of the current study demonstrated that a reduction of fluid collection by <50% following PCD, a maximum extent of peripancreatic necrosis of >50% and multiple organ failure are effective predictors of necrosectomy in patients with INP following PCD failure.
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Copy and paste a formatted citation
Spandidos Publications style
Cao X, Cao F, Li A, Gao X, Wang XH, Liu DG, Fang Y, Guo DH and Li F: Predictive factors of pancreatic necrosectomy following percutaneous catheter drainage as a primary treatment of patients with infected necrotizing pancreatitis. Exp Ther Med 14: 4397-4404, 2017.
APA
Cao, X., Cao, F., Li, A., Gao, X., Wang, X., Liu, D. ... Li, F. (2017). Predictive factors of pancreatic necrosectomy following percutaneous catheter drainage as a primary treatment of patients with infected necrotizing pancreatitis. Experimental and Therapeutic Medicine, 14, 4397-4404. https://doi.org/10.3892/etm.2017.5107
MLA
Cao, X., Cao, F., Li, A., Gao, X., Wang, X., Liu, D., Fang, Y., Guo, D., Li, F."Predictive factors of pancreatic necrosectomy following percutaneous catheter drainage as a primary treatment of patients with infected necrotizing pancreatitis". Experimental and Therapeutic Medicine 14.5 (2017): 4397-4404.
Chicago
Cao, X., Cao, F., Li, A., Gao, X., Wang, X., Liu, D., Fang, Y., Guo, D., Li, F."Predictive factors of pancreatic necrosectomy following percutaneous catheter drainage as a primary treatment of patients with infected necrotizing pancreatitis". Experimental and Therapeutic Medicine 14, no. 5 (2017): 4397-4404. https://doi.org/10.3892/etm.2017.5107
Copy and paste a formatted citation
x
Spandidos Publications style
Cao X, Cao F, Li A, Gao X, Wang XH, Liu DG, Fang Y, Guo DH and Li F: Predictive factors of pancreatic necrosectomy following percutaneous catheter drainage as a primary treatment of patients with infected necrotizing pancreatitis. Exp Ther Med 14: 4397-4404, 2017.
APA
Cao, X., Cao, F., Li, A., Gao, X., Wang, X., Liu, D. ... Li, F. (2017). Predictive factors of pancreatic necrosectomy following percutaneous catheter drainage as a primary treatment of patients with infected necrotizing pancreatitis. Experimental and Therapeutic Medicine, 14, 4397-4404. https://doi.org/10.3892/etm.2017.5107
MLA
Cao, X., Cao, F., Li, A., Gao, X., Wang, X., Liu, D., Fang, Y., Guo, D., Li, F."Predictive factors of pancreatic necrosectomy following percutaneous catheter drainage as a primary treatment of patients with infected necrotizing pancreatitis". Experimental and Therapeutic Medicine 14.5 (2017): 4397-4404.
Chicago
Cao, X., Cao, F., Li, A., Gao, X., Wang, X., Liu, D., Fang, Y., Guo, D., Li, F."Predictive factors of pancreatic necrosectomy following percutaneous catheter drainage as a primary treatment of patients with infected necrotizing pancreatitis". Experimental and Therapeutic Medicine 14, no. 5 (2017): 4397-4404. https://doi.org/10.3892/etm.2017.5107
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