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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November-2017 Volume 14 Issue 5

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Article Open Access

Effect of tendon hydrogel on healing of tendon injury Retraction in /10.3892/etm.2018.6022

Zheng Chen, Yongjun Rui, Yajun Xu, Quanrong Zhang, Zhenzhong Sun, Jiandong Zhou, Xueming Chen
Pages: 3955-3960
Published online on: 24 August 2017

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Case Report Open Access

Stent retriever thrombectomy combined with local thrombolytic therapy for cerebral venous sinus thrombosis: A case report Corrigendum in /10.3892/etm.2017.5676

Chengwei Chen, Qiujing Wang, Xifeng Li, Ziming Lu, Jian He, Qinrui Fang, Xunchang Ke, Chuanzhi Duan, Tielin Li
Pages: 3961-3970
Published online on: 28 August 2017

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Article Open Access

Intranasal application of glucocorticoid alleviates olfactory dysfunction in mice with allergic rhinitis

Xiaowei Wang, Yingying Zhu, Daofeng Ni, Wei Lv, Zhiqiang Gao, Fang Qi
Pages: 3971-3978
Published online on: 28 August 2017

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Case Report Open Access

Dasatinib and chemotherapy in a patient with early T‑cell precursor acute lymphoblastic leukemia and NUP214‑ABL1 fusion: A case report

Yan Chen, Li Zhang, Jiankun Huang, Xiuli Hong, Jiangning Zhao, Zhao Wang, Kejie Zhang
Pages: 3979-3984
Published online on: 28 August 2017

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Article Open Access

Expression of and correlation between BCL6 and ZEB family members in patients with breast cancer

Lin Ang, Li Zheng, Jin Wang, Jin Huang, Hong‑Guang Hu, Qiang Zou, Yang Zhao, Qiang‑Ming Liu, Min Zhao, Zheng‑Sheng Wu
Pages: 3985-3992
Published online on: 05 September 2017

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Article Open Access

Abnormal expression of microRNA‑575 leads to missed abortion through regulating apoptosis and angiogenesis

Shuqin Xia, Yihui Zhen, Hongsheng Ma, Aiming Wang
Pages: 3993-4000
Published online on: 31 August 2017

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Article Open Access

Bio‑Oss® modified by calcitonin gene‑related peptide promotes osteogenesis in vitro

Yuanjing Li, Lan Yang, Zhichao Zheng, Zhengmao Li, Tian Deng, Wen Ren, Caijuan Wu, Lvhua Guo
Pages: 4001-4008
Published online on: 28 August 2017

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Article Open Access

Adrenomedullin inhibits osteoclast differentiation through the suppression of receptor activator of nuclear factor‑κB ligand‑induced nuclear factor‑κB activation in glucocorticoid‑induced osteoporosis

Yuanxin Liu, Guilai Zuo, Xin Meng, Xingxiao Gao, Lihai Zhang, Peifu Tang
Pages: 4009-4016
Published online on: 24 August 2017

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Article Open Access

Comparison of effectiveness and adverse effects of gefitinib, erlotinib and icotinib among patients with non‑small cell lung cancer: A network meta‑analysis

Yuanyuan Liu, Yu Zhang, Gangling Feng, Qiang Niu, Shangzhi Xu, Yizhong Yan, Shugang Li, Mingxia Jing
Pages: 4017-4032
Published online on: 01 September 2017

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Article Open Access

Influence of reactive oxygen species on secretory component in the intestinal epithelium during hyperoxia

Min Zhao, Shimiao Tang, Junchi Xin, Dongyan Liu
Pages: 4033-4040
Published online on: 24 August 2017

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Article Open Access

Highly pathogenic avian influenza A virus H5N1 non‑structural protein 1 is associated with apoptotic activation of the intrinsic mitochondrial pathway

Qian Bian, Jing Lu, Li Zhang, Ying Chi, Yan Li, Hongxiong Guo
Pages: 4041-4046
Published online on: 28 August 2017

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Article Open Access

Curcumin inhibits endoplasmic reticulum stress induced by cerebral ischemia‑reperfusion injury in rats

Haiying Zhu, Yanxia Fan, Hongyu Sun, Liyan Chen, Xiao Man
Pages: 4047-4052
Published online on: 25 August 2017

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Article Open Access

MicroRNA‑155 regulates the proliferation, cell cycle, apoptosis and migration of colon cancer cells and targets CBL

Hua Yu, Weiling Xu, Fangchao Gong, Baorong Chi, Junyi Chen, Ling Zhou
Pages: 4053-4060
Published online on: 31 August 2017

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Article Open Access

Smart watch‑based coaching with tiotropium and olodaterol ameliorates physical activity in patients with chronic obstructive pulmonary disease

Osamu Hataji, Yoichi Nishii, Kentaro Ito, Tadashi Sakaguchi, Haruko Saiki, Yuta Suzuki, Corina D'Alessandro‑Gabazza, Hajime Fujimoto, Tetsu Kobayashi, Esteban C. Gabazza, Osamu Taguchi
Pages: 4061-4064
Published online on: 01 September 2017

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Article Open Access

High expression of long chain acyl‑coenzyme A synthetase 1 in peripheral blood may be a molecular marker for assessing the risk of acute myocardial infarction

Liping Yang, Yushuang Yang, Daoyuan Si, Kaiyao Shi, Dongna Liu, Heyu Meng, Fanbo Meng
Pages: 4065-4072
Published online on: 01 September 2017

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Case Report Open Access

Treatment of gout combined with Kienböck's disease: A case report

Hui Lu, Qiang Chen, Hang Yu, Zhenfeng Liu
Pages: 4073-4076
Published online on: 25 August 2017

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Article Open Access

The protective effects of ischemic preconditioning on rats with renal ischemia-reperfusion injury and the effects on the expression of Bcl-2 and Bax

Sheng Shen, Jiexue Zhou, Shandong Meng, Jiaqing Wu, Juan Ma, Chunli Zhu, Gengguo Deng, Dong Liu
Pages: 4077-4082
Published online on: 28 August 2017

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Article Open Access

Artemether suppresses cell proliferation and induces apoptosis in diffuse large B cell lymphoma cells

Xinying Zhao, Xudong Guo, Wenqin Yue, Jianmin Wang, Jianmin Yang, Jie Chen
Pages: 4083-4090
Published online on: 29 August 2017

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Article Open Access

Comparison of the effects of minimally invasive percutaneous pedicle screws osteosynthesis and open surgery on repairing the pain, inflammation and recovery of thoracolumbar vertebra fracture

Yahui Gong, Guangmin Fu, Bo Li, Yinan Li, Xiaoning Yang
Pages: 4091-4096
Published online on: 25 August 2017

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Article Open Access

Upregulation of microRNA‑206 induces apoptosis of vascular smooth muscle cells and decreases risk of atherosclerosis through modulating FOXP1

Tao Xing, Lixin Du, Xianbo Zhuang, Liyong Zhang, Jiheng Hao, Jiyue Wang
Pages: 4097-4103
Published online on: 30 August 2017

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Article Open Access

Renal sympathetic denervation improves myocardial apoptosis in rats with isoproterenol‑induced heart failure by downregulation of tumor necrosis factor‑α and nuclear factor‑κB

Wei Yao, Neng Wang, Jin Qian, Lu Bai, Xiaoxin Zheng, Guo Hou, Xuan Qiu, Bo Yang
Pages: 4104-4110
Published online on: 30 August 2017

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Article Open Access

Growth/differentiation factor‑5 promotes in vitro/vivo periodontal specific differentiation of induced pluripotent stem cell‑derived mesenchymal stem cells

Xiaohui Yin, Peng Li, Yang Li, Yu Cai, Jinhua Wen, Qingxian Luan
Pages: 4111-4117
Published online on: 25 August 2017

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Article Open Access

Magnetic resonance spectroscopy for assessment of brain injury in the rat model of sepsis

Miaoyun Wen, Zhesi Lian, Linqiang Huang, Senzhi Zhu, Bei Hu, Yongli Han, Yiyu Deng, Hongke Zeng
Pages: 4118-4124
Published online on: 25 August 2017

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Article Open Access

Association between B7‑H1 and cervical cancer: B7‑H1 impairs the immune response in human cervical cancer cells

Jianying Tao, Jianrong Dai, Shunyu Hou
Pages: 4125-4133
Published online on: 05 September 2017

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Article Open Access

Berberine ameliorates non‑alcoholic steatohepatitis in ApoE-/- mice

Jin Yang, Xiao‑Jie Ma, Ling Li, Lei Wang, Ying‑Gi Chen, Jing Liu, Yan Luo, Zhen‑Jie Zhuang, Wen‑Jun Yang, Shu‑Fei Zang, Jun‑Ping Shi
Pages: 4134-4140
Published online on: 28 August 2017

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Article Open Access

Electrospun collagen/poly(L-lactic acid‑co‑ε‑caprolactone) scaffolds for conjunctival tissue engineering

Qinke Yao, Weijie Zhang, Yang Hu, Junzhao Chen, Chunyi Shao, Xianqun Fan, Yao Fu
Pages: 4141-4147
Published online on: 30 August 2017

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Article Open Access

Ocular pulse amplitude in different types of glaucoma using dynamic contour tonometry: Diagnosis and follow‑up of glaucoma

Lingyan Cheng, Yuzhi Ding, Xuanchu Duan, Zhifeng Wu
Pages: 4148-4152
Published online on: 30 August 2017

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Article Open Access

Fucoidan elevates surface organic cation transporter 2 expression via upregulation of protein kinase A in uric acid nephropathy

Xinlin Wu, Miansheng Yan, Taoli Liu, Jiantang Liao, Jianqing Zhang, Shuqing Chen, Wei Deng, Shijun Zhang, Baoguo Sun, Houming Zhou, Bin Ke
Pages: 4153-4159
Published online on: 30 August 2017

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Article Open Access

Isolation and characterization of human umbilical cord‑derived endothelial colony‑forming cells

Hao Zhang, Yanling Tao, Saisai Ren, Haihui Liu, Hui Zhou, Jiangwei Hu, Yongyong Tang, Bin Zhang, Hu Chen
Pages: 4160-4166
Published online on: 25 August 2017

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Article Open Access

Molecular epidemiology study of measles viruses in Kunming area of China

Xiaoli Shang, Juan Wang, Xiaojuan Xu, Maoqing Ye, Xiaoling Xia
Pages: 4167-4173
Published online on: 25 August 2017

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Article Open Access

Echinocystic acid ameliorates hyperhomocysteinemia‑induced vascular endothelial cell injury through regulating NF‑κB and CYP1A1

Chuan‑Feng Huang, Wei‑Na Wang, Cheng‑Cao Sun, Yu‑Qing Wang, Ling Li, Yin Li, De‑Jia Li
Pages: 4174-4180
Published online on: 01 September 2017

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Article Open Access

Endogenous Nampt upregulation is associated with diabetic nephropathy inflammatory‑fibrosis through the NF‑κB p65 and Sirt1 pathway; NMN alleviates diabetic nephropathy inflammatory‑fibrosis by inhibiting endogenous Nampt

Ye Chen, Yuzhen Liang, Tingting Hu, Riming Wei, Congjie Cai, Ping Wang, Lingyu Wang, Wei Qiao, Leping Feng
Pages: 4181-4193
Published online on: 01 September 2017

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Article Open Access

Upregulation of T‑cadherin suppresses cell proliferation, migration and invasion of gastric cancer in vitro

Jianqing Lin, Zhiyao Chen, Zhijun Huang, Feng Chen, Zeyi Ye, Shaoze Lin, Weidong Wang
Pages: 4194-4200
Published online on: 01 September 2017

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Article Open Access

Mechanism of myocardial ischemia/reperfusion‑induced acute kidney injury through DJ‑1/Nrf2 pathway in diabetic rats

Qian Sun, Zi‑Ying Shen, Wei‑Na Duan, Qing‑Tao Meng, Zhong‑Yuan Xia
Pages: 4201-4207
Published online on: 01 September 2017

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Article Open Access

Evaluation of the diagnostic performance of panfungal polymerase chain reaction assay in invasive fungal diseases

Guo‑Jun Cao, Zhi‑Fang Xing, Li Hua, Yu‑Hua Ji, Jia‑Bin Sun, Zhen Zhao
Pages: 4208-4214
Published online on: 31 August 2017

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Article Open Access

Role of blocking Adam10 hydrolysis site on n‑cadherin by single‑chain antibody in ventricular remodeling

Xiaoou Li, Wei Huang, Bing He, Lirong Zhou, Xiaogang Huang, Baozhen Yao
Pages: 4215-4223
Published online on: 28 August 2017

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Article Open Access

Caffeoylxanthiazonoside exerts cardioprotective effects during chronic heart failure via inhibition of inflammatory responses in cardiac cells

Bin Yang, Fei Wang, Huili Cao, Guifang Liu, Yuean Zhang, Ping Yan, Bao Li
Pages: 4224-4230
Published online on: 31 August 2017

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Article Open Access

Snail1 is positively correlated with atrial fibrosis in patients with atrial fibrillation and rheumatic heart disease

Furong Guo, Xin Yi, Mingjiang Li, Jinrong Fu, Sha Li
Pages: 4231-4237
Published online on: 31 August 2017

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Article Open Access

Conventional vs. pulsed‑light accelerated corneal collagen cross‑linking for the treatment of progressive keratoconus: 12‑month results from a prospective study

Liang‑Zhu Jiang, Wei Jiang, Shi‑Yan Qiu
Pages: 4238-4244
Published online on: 25 August 2017

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Article Open Access

Effects of FHL1 and P21 on hypoxia‑induced pulmonary vascular remodeling in neonatal rats

Yanna Du, Jianhua Fu, Li Yao, Dan Zhang, Na Liu, Xindong Xue
Pages: 4245-4253
Published online on: 28 August 2017

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Article Open Access

TIAM1 inhibits lung fibroblast differentiation in pulmonary fibrosis

Zhicheng Huang, Shuangyan Sun, Changliang Yang, Jun Zheng, Yingji Nan, Ruikun Zhao, Zhiguo Lang, Hang Li, Lixia Ma
Pages: 4254-4262
Published online on: 24 August 2017

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Article Open Access

Vascular endothelial growth receptor 1 acts as a stress‑associated protein in the therapeutic response to thalidomide

Qin Liu, Tao Yin, Guoping Wang, Fuchun Guo, Yuhong Ou, Yi Li, Yongsheng Wang
Pages: 4263-4271
Published online on: 24 August 2017

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Article Open Access

Penehyclidine hydrochloride post‑conditioning reduces ischemia/reperfusion‑induced cardiomyocyte apoptosis in rats

Hongbao Tan, Li Chen, Jun Ma
Pages: 4272-4278
Published online on: 01 September 2017

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Article Open Access

Targeting Sirt1 in a rat model of high‑fat diet‑induced non‑alcoholic fatty liver disease: Comparison of Gegen Qinlian decoction and resveratrol

Yi Guo, Jun‑Xiang Li, Tang‑You Mao, Wei‑Han Zhao, Li‑Juan Liu, Yun‑Liang Wang
Pages: 4279-4287
Published online on: 30 August 2017

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Article Open Access

Inhibitory effects of PGA1 and TRI on the apoptosis of cardiac microvascular endothelial cells of rats

Wen-Hua Peng, Jia-Li Wang, Yan Ren, Yan-Xiang Gao, Geng Li, Yong Wang
Pages: 4288-4292
Published online on: 30 August 2017

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Article Open Access

Growth inhibitory effect of the Src inhibitor dasatinib in combination with anticancer agents on uterine cervical adenocarcinoma cells

Eri Takiguchi, Masato Nishimura, Ayuka Mineda, Takako Kawakita, Akiko Abe, Minoru Irahara
Pages: 4293-4299
Published online on: 28 August 2017

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Article Open Access

Evaluation of in vitro and in vivo therapeutic antitumor efficacy of transduction of polo‑like kinase 1 and heat shock transcription factor 1 small interfering RNA

Yoshiyuki Hattori, Takuto Kikuchi, Kei‑Ichi Ozaki, Hiraku Onishi
Pages: 4300-4306
Published online on: 28 August 2017

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Article Open Access

Protective effect of sevoflurane on myocardial ischemia-reperfusion injury in rat hearts and its impact on HIF-1α and caspase-3 expression

Tao Zhou, Shanliang Guo, Shaolin Wang, Qiong Li, Mingsheng Zhang
Pages: 4307-4311
Published online on: 30 August 2017

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Article Open Access

Bone marrow mesenchymal stem cells repair the hippocampal neurons and increase the expression of IGF‑1 after cardiac arrest in rats

Xiahong Tang, Feng Chen, Qinming Lin, Yan You, Jun Ke, Shen Zhao
Pages: 4312-4320
Published online on: 28 August 2017

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Article Open Access

Contrast‑enhanced ultrasonography features of papillary thyroid carcinoma for predicting cervical lymph node metastasis

Ying Liu, Hong Zhou, Peng Yang, Yang Zhou, Jian Wu, Changyu Chen, Ming Ye, Jing Luo
Pages: 4321-4327
Published online on: 01 September 2017

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Article Open Access

Combined effect of linolenic acid and tobramycin on Pseudomonas aeruginosa biofilm formation and quorum sensing

Warren Chanda, Thomson Patrick Joseph, Arshad Ahmed Padhiar, Xuefang Guo, Liu Min, Wendong Wang, Sainyugu Lolokote, Anhong Ning, Jing Cao, Min Huang, Mintao Zhong
Pages: 4328-4338
Published online on: 05 September 2017

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Article

Reduced Gja5 expression in arterial endothelial cells impairs arteriogenesis during acute ischemic cardiovascular disease

Xiang‑Jun Lu, Hai‑Tao Wang
Pages: 4339-4343
Published online on: 30 August 2017

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Article

Photodynamic therapy for biliary tract organ via a novel ultra‑small composite optical fiberscope

Kazuhiko Kasuya, Kiyoshi Oka, Ryoko Soya, Takaaki Tsuchiya, Takao Itoi, Akihiko Tsuchida
Pages: 4344-4348
Published online on: 28 August 2017

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Article

Anti‑inflammatory effects of water extract from bell pepper (Capsicum annuum L. var. grossum) leaves in vitro

Mai Hazekawa, Yuko Hideshima, Kazuhiko Ono, Takuya Nishinakagawa, Tomoyo Kawakubo‑Yasukochi, Tomoka Takatani‑Nakase, Manabu Nakashima
Pages: 4349-4355
Published online on: 05 September 2017

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Article

Expression and significance of caveolin‑1 in hepatitis B virus‑associated hepatocellular carcinoma

Hao Cheng, Yiming Pan, Yongzhong Yao, Zhanghua Zhu, Jun Chen, Xitai Sun, Yudong Qiu, Yitao Ding
Pages: 4356-4362
Published online on: 25 August 2017

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Article

Advanced glycation end products and lipopolysaccharides stimulate interleukin‑6 secretion via the RAGE/TLR4‑NF‑κB‑ROS pathways and resveratrol attenuates these inflammatory responses in mouse macrophages

Ayaka Ohtsu, Yui Shibutani, Kotomi Seno, Hisataka Iwata, Takehito Kuwayama, Koumei Shirasuna
Pages: 4363-4370
Published online on: 28 August 2017

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Article

Identification of key signaling pathways in cerebral small vessel disease using differential pathway network analysis

Gang Zheng, Qianlei Zheng, Qianwei Xu
Pages: 4371-4376
Published online on: 05 September 2017

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Article

Effect of isoflurane + N2O inhalation and propofol + fentanyl anesthesia on myocardial function as assessed by cardiac troponin, caspase‑3, cyclooxygenase‑2 and inducible nitric oxide synthase expression

Zhuanghui Zhu, Shuanglian Yi, Zhonggui Shan, Hongwei Guo, Shaofan Ke
Pages: 4377-4382
Published online on: 25 August 2017

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Article

Spontaneously hypertensive rats are sensitive to thoracic aorta damage induced by a hot and humid environment

Tao Xu, Fadong Liu, Yan Luo, Lingqin Zhu, Jianguo Niu, Guanghua Li
Pages: 4383-4390
Published online on: 28 August 2017

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Article

Small interfering RNA directed against microRNA‑155 delivered by a lentiviral vector attenuates asthmatic features in a mouse model of allergic asthma

Huilong Chen, Xiangqin Xu, Sheng Cheng, Yuzhu Xu, Qi Xuefei, Yong Cao, Jungang Xie, Cong‑Yi Wang, Yongjian Xu, Weining Xiong
Pages: 4391-4396
Published online on: 01 September 2017

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Article

Predictive factors of pancreatic necrosectomy following percutaneous catheter drainage as a primary treatment of patients with infected necrotizing pancreatitis

Xi Cao, Feng Cao, Ang Li, Xiang Gao, Xiao‑Hui Wang, Dian‑Gang Liu, Yu Fang, Dong‑Hai Guo, Fei Li
Pages: 4397-4404
Published online on: 05 September 2017

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Preliminary screening of type IV secretion system in divergent geographic sources of Clostridium difficile

Na Li, Hongbing Jia, Hui Yang, Bing Ji, Yongyun Liu, Xinguo Peng, Ying Cheng, Wen Zhang
Pages: 4405-4410
Published online on: 29 August 2017

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Article

Effect of docosahexaenoic acid on traumatic brain injury in rats

Wei Zhu, Nan Chi, Peng Zou, Hongguang Chen, Guotai Tang, Wei Zhao
Pages: 4411-4416
Published online on: 28 August 2017

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Article

Plain and contrast‑enhanced chest computed tomography scan findings of pulmonary cryptococcosis in immunocompetent patients

Rongshui Yang, Yan Yan, Yuhuan Wang, Xiaohuan Liu, Xinhui Su
Pages: 4417-4424
Published online on: 01 September 2017

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Article

Naringenin inhibits transforming growth factor‑β1‑induced cardiac fibroblast proliferation and collagen synthesis via G0/G1 arrest

Mingxin Liu, Xiping Xu, Jianhua Zhao, Yanhong Tang
Pages: 4425-4430
Published online on: 05 September 2017

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Article

Tectorigenin attenuates the MPP+‑induced SH‑SY5Y cell damage, indicating a potential beneficial role in Parkinson's disease by oxidative stress inhibition

Ping Gong, Fang Deng, Wei Zhang, Jin Ji, Jia Liu, Yinan Sun, Jiayu Hu
Pages: 4431-4437
Published online on: 28 August 2017

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Article

Mast cell chymase promotes hypertrophic scar fibroblast proliferation and collagen synthesis by activating TGF‑β1/Smads signaling pathway

Hongming Chen, Yanwen Xu, Guanbin Yang, Qianqian Zhang, Xun Huang, Liming Yu, Xianglin Dong
Pages: 4438-4442
Published online on: 31 August 2017

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Article

MUC1 downregulation inhibits non‑small cell lung cancer progression in human cell lines

Tao Xu, Daowei Li, Hongmei Wang, Taohua Zheng, Guangqiang Wang, Ying Xin
Pages: 4443-4447
Published online on: 29 August 2017

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Article

MiR‑148a modulates HLA‑G expression and influences tumor apoptosis in esophageal squamous cell carcinoma

Quan Chen, Guanghua Luo, Xiaoying Zhang
Pages: 4448-4452
Published online on: 28 August 2017

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Article

Therapeutic effects of stemonine on particulate matter 2.5‑induced chronic obstructive pulmonary disease in mice

Jinbo Zhang, Shiqing Li, Li Sun, Yanxia Chen, Lei Zhang, Zhenghui Zhang
Pages: 4453-4459
Published online on: 01 September 2017

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Article

Simvastatin attenuates renal ischemia/reperfusion injury from oxidative stress via targeting Nrf2/HO‑1 pathway

Yu Zhang, Shu Rong, Yi Feng, Liqun Zhao, Jiang Hong, Ruilan Wang, Weijie Yuan
Pages: 4460-4466
Published online on: 24 August 2017

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Article

Effect of testosterone and hypoxia on the expansion of umbilical cord blood CD34+ cells in vitro

Liping Zhou, Xiaowei Zhang, Panpan Zhou, Xue Li, Xuejing Xu, Qing Shi, Dong Li, Xiuli Ju
Pages: 4467-4475
Published online on: 24 August 2017

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Article

Analgesic activity of cynaropicrinon on post‑inflammatory irritable bowel syndrome visceral hypersensitivity in a rat model

Hailong Shi, Xianwei Zhu, Yaya Cui, Yifei Qin, Lin Yang, Xu Deng
Pages: 4476-4482
Published online on: 25 August 2017

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Article

Alcoholization of pyogenichepatic abscess with absolute alcohol in Bama minipigs

Ru‑Gang Zhang, Xiu‑Li Zhang, Yun‑Sheng Yang
Pages: 4483-4488
Published online on: 24 August 2017

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Article

MicroRNA‑21 regulates the viability and apoptosis of diffuse large B‑cell lymphoma cells by upregulating B cell lymphoma‑2

Ke Liu, Jingxia Du, Linhai Ruan
Pages: 4489-4496
Published online on: 24 August 2017

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Article

Low copy number of FCGR3B is associated with lupus nephritis in a Chinese population

Zhaohui Zheng, Ruohan Yu, Congcong Gao, Xianan Jian, Songxia Quan, Guolan Xing, Shengyun Liu, Zhangsuo Liu
Pages: 4497-4502
Published online on: 30 August 2017

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Article

Long non‑coding RNA HOX transcript antisense RNA promotes expression of 14‑3‑3σ in non‑small cell lung cancer

Ranran Wang, Bin Yan, Zheng Li, Yiqun Jiang, Chao Mao, Xiang Wang, Xinmin Zhou
Pages: 4503-4508
Published online on: 28 August 2017

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Article

Bacterial keratitis: Photodynamic inactivation reduced experimental inflammation

Mona Deichelbohrer, Ming‑Feng Wu, Berthold Seitz, Dirk Hüttenberger, Matthias W. Laschke, Hans‑Jochen Foth, Bodo Wonnenberg, Stefan Wagenpfeil, Carola Meier, Markus Bischoff, Thomas Tschernig
Pages: 4509-4514
Published online on: 05 September 2017

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Article

Estimation of effective doses in pediatric X‑ray computed tomography examination

Hideki Obara, Midori Takahashi, Kazuya Kudou, Yasushi Mariya, Yoshihiro Takai, Ikuo Kashiwakura
Pages: 4515-4520
Published online on: 05 September 2017

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Article

Target‑controlled infusion of propofol and remifentanil combined with dexmedetomidine reduces functional endoscopic sinus surgery bleeding

Deng‑Feng Ding, Li‑Fang Wu, Ping Wang, Yuan‑Xu Jiang, Yao‑Wen Luo, Zhong‑Liang Dai, Xue‑Ping Zhang, Ya‑Li Li
Pages: 4521-4526
Published online on: 30 August 2017

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Article

The molecular mechanism of treating osteoarthritis with dipsacus saponins by inhibiting chondrocyte apoptosis

Xian‑Rang Li, Jian Li, Qiang Ren, Shui Sun
Pages: 4527-4532
Published online on: 30 August 2017

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Article

Role of IL‑15 in the modulation of TGF‑β1‑mediated inflammation in asthma

Mateusz Jonakowski, Jan Zioło, Marcelina Koćwin, Marcelina Przemęcka, Łukasz Mokros, Michał Panek, Janusz Szemraj, Piotr Kuna
Pages: 4533-4540
Published online on: 05 September 2017

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Article

Early surgery increases mitochondrial DNA release and lung injury in a model of elderly hip fracture and chronic obstructive pulmonary disease

Jianzheng Zhang, Juan Wang, Xiaowei Wang, Zhi Liu, Jixin Ren, Tiansheng Sun
Pages: 4541-4546
Published online on: 28 August 2017

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Article

Effects of wogonin on the mechanism of melanin synthesis in A375 cells

Xi Chen, Ting Gu, Jing‑Hua Wang, Hui Xiong, Ye‑Qiu Wang, Guo‑Liang Liu, Yan Qu, Ning Zhang
Pages: 4547-4553
Published online on: 30 August 2017

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Article

Expression and role of microRNA 18b and hypoxia inducible factor‑1α in placental tissues of preeclampsia patients

Shenglan Wang, Xuemei Wang, Zhanping Weng, Shuping Zhang, Hui Ning, Baolai Li
Pages: 4554-4560
Published online on: 30 August 2017

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Article

Evaluation of the efficacy of Ajuga decumbens extract supplement in individuals with knee discomfort associated with physical activity: A randomized, double‑blind, placebo‑controlled study

Yoko Sawada, Atsushi Sugimoto, Takehito Hananouchi, Norimasa Sato, Isao Nagaoka
Pages: 4561-4571
Published online on: 29 August 2017

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Article

Inhibition of miR‑27a suppresses the inflammatory response via the p38/MAPK pathway in intervertebral disc cells

Zhenguo Cao, Liang Chen
Pages: 4572-4578
Published online on: 28 August 2017

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Article

Synergistic enhancement of matrix metalloproteinase‑9 expression and pro‑inflammatory cytokines by influenza virus infection and oxidized‑LDL treatment in human endothelial cells

Yun Wu, He Huang
Pages: 4579-4585
Published online on: 01 September 2017

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Article

Lactobacillus raises in vitro anticancer effect of geniposide in HSC‑3 human oral squamous cell carcinoma cells

Zhou Cheng, Hui Xu, Xiaoping Wang, Zuoye Liu
Pages: 4586-4594
Published online on: 05 September 2017

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Article

Promotion of anoxia‑reoxygenation‑induced inflammation and permeability enhancement by nicotinamide phosphoribosyltransferase‑activated MAPK signaling in human umbilical vein endothelial cells

Nao Yan, Wei Yang, Xiao Dong, Qiao Fang, Yi Gong, Jian‑Liang Zhou, Jian‑Jun Xu
Pages: 4595-4601
Published online on: 31 August 2017

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Article

I‑BET151 inhibits expression of RANKL, OPG, MMP3 and MMP9 in ankylosing spondylitis in vivo and in vitro

Jianping Fan, Jian Zhao, Jie Shao, Xianzhao Wei, Xiaodong Zhu, Ming Li
Pages: 4602-4606
Published online on: 25 August 2017

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Review Open Access

Cardiovascular risks in chronic kidney disease pediatric patients (Review)

Jing Tian, Ling Niu, Xinjiang An
Pages: 4615-4619
Published online on: 15 September 2017

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Article Open Access

EGFR and Cortactin: Markers for potential double target therapy in oral squamous cell carcinoma

Oliver Bissinger, Andreas Kolk, Enken Drecoll, Melanie Straub, Christina Lutz, Klaus‑Dietrich Wolff, Carolin Götz
Pages: 4620-4626
Published online on: 18 September 2017

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Antitumor and immunomodulating activities of six Phellinus igniarius polysaccharides of different origins

Wenwen Gao, Wangdi Wang, Wenjian Sun, Mingfang Wang, Na Zhang, Shuwen Yu
Pages: 4627-4632
Published online on: 22 September 2017

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Identification of key genes influenced by fixation stability in early fracture hematoma and elucidation of their roles in fracture healing

Chengxue Wang, Baochang Qi, Congfeng Zhang, Jieping Cheng
Pages: 4633-4638
Published online on: 22 September 2017

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Effect of tanshinone IIA on oxidative stress and apoptosis in a rat model of fatty liver

Guan‑Lin Yang, Lian‑Qun Jia, Jin Wu, Yi‑Xin Ma, Hui‑Min Cao, Nan Song, Ni Zhang
Pages: 4639-4646
Published online on: 21 September 2017

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Protein‑protein interaction analysis to identify biomarker networks for endometriosis

Hong Xiao, Lihua Yang, Jianjun Liu, Yang Jiao, Lin Lu, Hongbo Zhao
Pages: 4647-4654
Published online on: 22 September 2017

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Electroacupuncture improves acute bowel injury recovery in rat models

Jiannong Wu, Bin Lyu, Tie'er Gan, Lingcong Wang, Meifei Zhu
Pages: 4655-4662
Published online on: 21 September 2017

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MgCl2 and ZnCl2 promote human umbilical vein endothelial cell migration and invasion and stimulate epithelial‑mesenchymal transition via the Wnt/β‑catenin pathway

Shuang Pan, Liwen An, Xin Meng, Liming Li, Fu Ren, Yifu Guan
Pages: 4663-4670
Published online on: 20 September 2017

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Small interfering RNA against ERK1/2 attenuates cigarette smoke‑induced pulmonary vascular remodeling

Muqing Yu, Xiansheng Liu, Hongxu Wu, Wang Ni, Shixin Chen, Yongjian Xu
Pages: 4671-4680
Published online on: 21 September 2017

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CHAF1A, the largest subunit of the chromatin assembly factor 1 complex, regulates the growth of H1299 human non‑small cell lung cancer cells by inducing G0/G1 cell cycle arrest

Tanzhen Liu, Jingjing Wei, Chao Jiang, Chen Wang, Xiaoqin Zhang, Yan Du, Jianqiang Li, Hui Zhao
Pages: 4681-4686
Published online on: 25 September 2017

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Long non‑coding RNA linc‑ITGB1 promotes cell proliferation and migration in human hepatocellular carcinoma cells

Meiling Shang, Xinhua Xu, Min Zhang, Hongyuan Yang
Pages: 4687-4692
Published online on: 20 September 2017

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p63 inhibits CD44+/CD24‑ cell proliferation and chemoresistance in papillary thyroid carcinoma cells

Jing‑Jing Guo, Hong‑Shun Xu, Gang Wu, Zhen‑Yu Ma
Pages: 4693-4696
Published online on: 19 September 2017

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A network pharmacology approach to investigate the pharmacological effects of Guizhi Fuling Wan on uterine fibroids

Liuting Zeng, Kailin Yang, Huiping Liu, Guomin Zhang
Pages: 4697-4710
Published online on: 21 September 2017

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An integrated bioinformatical analysis of miR‑19a target genes in multiple myeloma

Hongyan Lv, Xianda Wu, Guiru Ma, Lixia Sun, Jianbo Meng, Xiaoning Song, Jinqiao Zhang
Pages: 4711-4720
Published online on: 21 September 2017

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Construction of a novel vector expressing Survivin‑shRNA and fusion suicide gene yCDglyTK and its application in inhibiting proliferation and migration of colon cancer cells

Ling Ye, Yuan Yang, Xin‑Yu Ma, Dan Li, Mei‑Li Xu, Pan Tan, Li‑Min Long, Hai‑Qin Wang, Ting Liu, Yong‑Hong Guo
Pages: 4721-4728
Published online on: 20 September 2017

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Serological evaluation of antigen Tp0693 for diagnosis of syphilis

Li Zhang, Meixia Deng, Xiaohong Zhang, Weiguo Yin, Wen Liu, Xi Luo, Jie Yang, Fei Chen, Feijun Zhao
Pages: 4729-4736
Published online on: 21 September 2017

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Effects of activated carbon N‑acetylcysteine sustained‑release microcapsule on dipeptidyl peptidase IV expression in young rats with non‑alcoholic fatty liver disease

Hongping Zhou, Tingting Shi, Jun Yan, Xiaojin Chen, Li Liao, Shiyong Zhao, Hongying Fang, Rangxiao Zhuang
Pages: 4737-4744
Published online on: 19 September 2017

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Anti‑inflammatory effects of Fagopyrum cymosum administered as a potential drug for ulcerative colitis

Fei Ge, Shilin Zhu, Lina Liu, Jing Yan, Yu Ji, Zhiguang Sun
Pages: 4745-4754
Published online on: 20 September 2017

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In vivo and in vitro studies on the roles of p38 mitogen‑activated protein kinase and NADPH‑cytochrome P450 reductase in Alzheimer's disease

Yunyi Yao, Jin‑Zhong Huang, Liang Chen, Yingqi Chen, Xianhong Li
Pages: 4755-4760
Published online on: 22 September 2017

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Diagnostic value of 64‑slice spiral computed tomography imaging of the urinary tract during the excretory phase for urinary tract obstruction

De‑Li Zhao, Guang‑Sheng Jia, Peng Chen, Xin‑Ding Liu, Sheng‑Jie Shu, Zai‑Sheng Ling, Ting‑Ting Fan, Xiu‑Fen Shen, Jin‑Ling Zhang
Pages: 4761-4766
Published online on: 21 September 2017

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Analgesic therapy improves arterial endothelial function following non‑cardiovascular surgery: A randomized, placebo‑controlled trial

Meng‑Jun Wu, Meng‑Chang Yang, Long‑Qing Ran, Su‑Mei Wei, Wen‑Lai Zhou, Yong‑Sheng Gou, Hai Yu
Pages: 4767-4772
Published online on: 19 September 2017

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Gemcitabine treatment causes resistance and malignancy of pancreatic cancer stem‑like cells via induction of lncRNA HOTAIR

Li Wang, Ping Dong, Weiguo Wang, Mingquan Huang, Bole Tian
Pages: 4773-4780
Published online on: 20 September 2017

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Rapid visual detection of binary toxin producing Clostridium difficile by loop‑mediated isothermal amplification

Lan Yu, Huan Li, Xiangna Zhao, Xuesong Wang, Xiao Wei, Weishi Lin, Puyuan Li, Lihong Cui, Jing Yuan
Pages: 4781-4788
Published online on: 21 September 2017

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Long‑term exposure to ethanol downregulates tight junction proteins through the protein kinase Cα signaling pathway in human cerebral microvascular endothelial cells

Hao Yu, Changliang Wang, Xiaolong Wang, Hongbo Wang, Chunan Zhang, Jiabin You, Pengfei Wang, Chunmei Feng, Guohui Xu, Rui Zhao, Xu Wu, Guohua Zhang
Pages: 4789-4796
Published online on: 21 September 2017

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Uterine artery blood flow and microvessel density by vaginal color Doppler ultrasonography in embryo implantation failure

Zhen Li, Xingling Wang, Yichun Guan, Xiaona Yu, Jing Liu, Zhan Zhang
Pages: 4797-4800
Published online on: 08 September 2017

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The efficacy of gastrodin in combination with folate and vitamin B12 on patients with epilepsy after stroke and its effect on HMGB-1, IL-2 and IL-6 serum levels

Hao Zhou, Nuan Wang, Lei Xu, Hongli Huang, Chunyu Yu
Pages: 4801-4806
Published online on: 14 September 2017

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Role of miR-124a in T cell activation and immunity in AIDS patients

Wenge Zhao, Chuansheng Liu, Changhe Shi, Tianli Fan, Kaiqiu Chu, Yanli Ma
Pages: 4807-4812
Published online on: 15 September 2017

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The expression and significance of tyrosine hydroxylase in the brain tissue of Parkinson's disease rats

Yuan Chen, Yajun Lian, Yunqing Ma, Chuanjie Wu, Yake Zheng, Nanchang Xie
Pages: 4813-4816
Published online on: 18 September 2017

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Relationship of SOCS3 and TGF-β with IDO expression in early pregnancy chorionic villi and decidua

Wei Liu, Yongli Huang, Guanyou Huang, Congrong Zhou, Xiaoling Zeng, Shuyun Zhao, Lingfei Wu, Hua Zhou, Qingqing Wu, Lujun Dai
Pages: 4817-4824
Published online on: 19 September 2017

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Topically administered rhGM-CSF affects PPARβ expression in the stasis zone

Gen-Feng Fu, She-Min Tian, Xin-Jian Cha, Hong-Jun Huang, Ji-He Lou, Ying Wei, Cheng-De Xia, Yong-Lin Li, Xi-Hua Niu
Pages: 4825-4830
Published online on: 20 September 2017

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Shuyu capsules relieve liver‑qi depression by regulating ERK‑CREB‑BDNF signal pathway in central nervous system of rat

Hongyan Wang, Yingquan Zhang, Helou Li, Wei Zeng, Mingqi Qiao
Pages: 4831-4838
Published online on: 18 September 2017

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Simvastatin augments activation of liver regeneration through attenuating transforming growth factor‑β1 induced‑apoptosis in obstructive jaundice rats

Dazheng Fang, Ying He, Zhou Luan
Pages: 4839-4845
Published online on: 21 September 2017

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miR‑30c may serve a role in endometriosis by targeting plasminogen activator inhibitor‑1

Xiaoli Chen, Yan Jiang, Dianling Pan
Pages: 4846-4852
Published online on: 20 September 2017

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Pigment epithelium‑derived factor short peptides facilitate full‑thickness cutaneous wound healing by promoting epithelial basal cell and hair follicle stem cell proliferation

Shawn H. Tsai, Li‑Pen Tsao, Shih‑Hsin Chang, Tsung‑Chuan Ho, Kwang‑Yi Tung, Ai‑Ching Wu, Yeou‑Ping Tsao
Pages: 4853-4861
Published online on: 19 September 2017

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Overexpression of epithelial cell transforming 2 protein in colorectal carcinoma predicts a poor prognosis

Yiming Li, Xiangjun Cai, Bo Chen, Hanbo Gu, Caigang Liu
Pages: 4862-4868
Published online on: 19 September 2017

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Extended magnetic resonance imaging studies on the effect of classically activated microglia transplantation on white matter regeneration following spinal cord focal injury in adult rats

Wiesław Marcol, Wojciech Ślusarczyk, Magdalena Larysz‑Brysz, Krzysztof Łabuzek, Bartosz Kapustka, Rafał Staszkiewicz, Paulina Rosicka, Katarzyna Kalita, Władysław Węglarz, Joanna Lewin‑Kowalik
Pages: 4869-4877
Published online on: 19 September 2017

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Daidzein ameliorates spinal cord ischemia/reperfusion injury‑induced neurological function deficits in Sprague-Dawley rats through PI3K/Akt signaling pathway

Fan Zhang, Neng Ru, Zheng‑Hui Shang, Jian‑Feng Chen, Chao Yan, Yun Li, Jie Liang
Pages: 4878-4886
Published online on: 21 September 2017

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Effect of different treatments and alcohol addiction on gut microbiota in minimal hepatic encephalopathy patients

Zan Zuo, Hong Fan, Xiao‑Dan Tang, Yan‑Min Chen, Lin‑Ting Xun, Yan Li, Zheng‑Ji Song, Hui‑Qiong Zhai
Pages: 4887-4895
Published online on: 19 September 2017

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Genome-wide association study for SNPs associated with PCOS in human patients

Li Chen, Ling-Min Hu, Yu-Feng Wang, Hai-Yan Yang, Xiao-Yang Huang, Wei Zhou, Hai-Xiang Sun
Pages: 4896-4900
Published online on: 07 September 2017

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Protective effect of zoledronic acid on articular cartilage and subchondral bone of rabbits with experimental knee osteoarthritis

Guorong She, Ziqi Zhou, Zhengang Zha, Fei Wang, Xiaoting Pan
Pages: 4901-4909
Published online on: 19 September 2017

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Anti‑nociceptive effect of dexmedetomidine in a rat model of monoarthritis via suppression of the TLR4/NF‑κB p65 pathway

Dong Ji, Yalan Zhou, Shuangshuang Li, Dai Li, Hui Chen, Yuanchang Xiong, Yuqiu Zhang, Hua Xu
Pages: 4910-4918
Published online on: 22 September 2017

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Lycium barbarum polysaccharide protects against neurotoxicity via the Nrf2‑HO‑1 pathway

Shumei Cao, Jianlong Du, Qiaohong Hei
Pages: 4919-4927
Published online on: 19 September 2017

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Expression of Foxp3 in renal tissue of patients with HBV-associated glomerulonephritis and their clinical and pathological characteristics

Wenge Zhao, Yanli Ma, Mingmin Wang, Changhe Shi, Jianping Sun, Kaiqiu Chu, Chuansheng Liu
Pages: 4928-4934
Published online on: 05 September 2017

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Calcitonin gene‑related peptide has protective effect on brain injury induced by heat stroke in rats

Cheng‑Xiang Lu, Ting Qiu, Zhi‑Feng Liu, Lei Su, Biao Cheng
Pages: 4935-4941
Published online on: 18 September 2017

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Comparison of the effect of rosuvastatin versus rosuvastatin/ezetimibe on markers of inflammation in patients with acute myocardial infarction

Yizhi Ren, Hao Zhu, Zhongguo Fan, Yali Gao, Nailiang Tian
Pages: 4942-4950
Published online on: 21 September 2017

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LYTAK1 attenuates proliferation of retinal pigment epithelial cells through TGF‑β‑mediated epithelial‑mesenchymal transition via the ERK/AKT signaling pathway

Zhen Chen, Ninghua Ni, Yan Mei, Zhengrong Yang
Pages: 4951-4957
Published online on: 22 September 2017

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Effect of a stilbene glycoside‑rich extract from Polygoni Multiflori Radix on experimental non‑alcoholic fatty liver disease based on principal component and orthogonal partial least squares discriminant analysis

Zhaohuan Lou, Bohou Xia, Jie Su, Jingjing Yu, Meiqiu Yan, Yuefang Huang, Guiyuan Lv
Pages: 4958-4966
Published online on: 22 September 2017

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Spatial and temporal expression of Smad signaling members during the development of mandibular condylar cartilage

Di Xiao, Ru Wang, Jing Hu, Huixin Quan
Pages: 4967-4971
Published online on: 22 September 2017

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Influence of serum HMW adiponectin level in patients with pregnancy-induced hypertension syndrome on the occurrence of eclampsia in secondary pregnancy

Qian Xu, Dongmei Fan, Fahong Li, Zhanhong Zhang
Pages: 4972-4976
Published online on: 07 September 2017

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Ginsenoside Rg3 induces ginsenoside Rb1-comparable cardioprotective effects independent of reducing blood pressure in spontaneously hypertensive rats

Yichuan Jiang, Min Li, Zeyuan Lu, Yuchen Wang, Xiaofeng Yu, Dayun Sui, Li Fu
Pages: 4977-4985
Published online on: 22 September 2017

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Butanol extracts of Asparagus cochinchinensis fermented with Weissella cibaria inhibit iNOS‑mediated COX‑2 induction pathway and inflammatory cytokines in LPS‑stimulated RAW264.7 macrophage cells

Hyun Ah Lee, Bo Ram Song, Hye Ryeong Kim, Ji Eun Kim, Woo Bin Yun, Jin Ju Park, Mi Lim Lee, Jun Young Choi, Hee Seob Lee, Dae Youn Hwang
Pages: 4986-4994
Published online on: 25 September 2017

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A rabbit model of implant‑related osteomyelitis inoculated with biofilm after open femoral fracture

Xiang Zhang, Yun‑Fei Ma, Lei Wang, Nan Jiang, Cheng‑He Qin, Yan‑Jun Hu, Bin Yu
Pages: 4995-5001
Published online on: 19 September 2017

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Analysis of the correlation between adiponectin gene polymorphism and metabolic syndrome incidence and its relationship with the degree of atherosclerosis in patients

Guangya Wang, Guangyao Song, Linxia Wang, Fang Gao, Ningning Guo, Yunna Zhang, Nairui Zhao, Xiuping Yin
Pages: 5002-5006
Published online on: 20 September 2017

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Bone engineering by cell sheet technology to repair mandibular defects

Xiuli Shan, Deshan Hu
Pages: 5007-5011
Published online on: 15 September 2017

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Combined treatment of diabetic nephropathy with alprostadil and calcium dobesilate

Lili Qin, Wenjun Qin, Jianfei Wang, Lin Lin
Pages: 5012-5016
Published online on: 12 September 2017

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Clinical significance of novel biomarker NGAL in early diagnosis of acute renal injury

Jinghua Zhang, Jianle Han, Jinrui Liu, Bing Liang, Xiaobo Wang, Changan Wang
Pages: 5017-5021
Published online on: 20 September 2017

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The content of hydrogen sulfide in plasma of cirrhosis rats combined with portal hypertension and the correlation with indexes of liver function and liver fibrosis

Weiwei Wei, Chao Wang, Dongjian Li
Pages: 5022-5026
Published online on: 19 September 2017

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Correlation of the expression of miR-146a in peripheral blood mononuclear cells of patients with ankylosing spondylitis and inflammatory factors

Chengjun Wei, Hongxia Zhang, Chenghong Wei, Youyan Mao
Pages: 5027-5031
Published online on: 21 September 2017

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Article

Protective effects of resveratrol on osteoporosis via activation of the SIRT1‑NF‑κB signaling pathway in rats

Xiaowei Wang, Liaobin Chen, Wei Peng
Pages: 5032-5038
Published online on: 20 September 2017

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Article

Effects of freshwater clam extract on fracture induced inflammation at early stage

Kuang‑Ting Yeh, Wen‑Tien Wu, Yi‑Maun Subeq, Chi‑Chien Niu, Kuang‑Wen Liao, Ing‑Ho Chen, Ru‑Ping Lee
Pages: 5039-5044
Published online on: 22 September 2017

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Anti‑aging effect of fullerenol on skin aging through derived stem cells in a mouse model

Wei Li, Ning Li, Bing Sui, Daping Yang
Pages: 5045-5050
Published online on: 21 September 2017

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Protective role of tenuigenin on sepsis‑induced acute kidney injury in mice

Yan Xu, Yan Jiang, Wentao Gai, Botao Yu
Pages: 5051-5056
Published online on: 21 September 2017

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Article

Sirt1 regulates apoptosis and extracellular matrix degradation in resveratrol‑treated osteoarthritis chondrocytes via the Wnt/β‑catenin signaling pathways

Shuan Liu, Hongping Yang, Bing Hu, Mingyong Zhang
Pages: 5057-5062
Published online on: 21 September 2017

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Article

Contrast‑enhanced computerized tomography combined with a targeted nanoparticle contrast agent for screening for early‑phase non‑small cell lung cancer

Ninglu Yuan, Xiaohe Zhang, Yonghui Cao, Xiaojie Jiang, Si Zhao, Yingying Feng, Yimeng Fan, Zhitao Lu, Hongmei Gao
Pages: 5063-5068
Published online on: 19 September 2017

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Article

Role of microRNA‑26a in the diagnosis of lower extremity deep vein thrombosis in patients with bone trauma

Zi Li, Jiangdong Ni
Pages: 5069-5074
Published online on: 22 September 2017

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Article

Curcumin inhibits the development of non‑small cell lung cancer by inhibiting autophagy and apoptosis

Aili Wang, Jinxiang Wang, Shuming Zhang, Hongxia Zhang, Zhenyang Xu, Xiaohui Li
Pages: 5075-5080
Published online on: 21 September 2017

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Article

SVP‑B5 peptide from Buthus martensii Karsch scorpion venom exerts hyperproliferative effects on irradiated hematopoietic cells

Yan Wang, Baiqian Xing, Ting Li, Caixia Wang, Meixun Zhou, Yamin Liu, Lingjie Fan, Lili Hu, Xiang Peng, Yongxin Xiang, Han Wang, Tianhan Kong, Weihua Dong, Qifeng Guo
Pages: 5081-5086
Published online on: 20 September 2017

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Blockade of 146b‑5p promotes inflammation in atherosclerosis‑associated foam cell formation by targeting TRAF6

Nan Lin, Yi An
Pages: 5087-5092
Published online on: 18 September 2017

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Article

Rigid laryngoscope manifestations of 61 cases of modern laryngeal tuberculosis

Ningjun Zhao, Yi Zhang, Keyong Li
Pages: 5093-5096
Published online on: 21 September 2017

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Article

Leptin upregulates COX‑2 and its downstream products in aortic endothelial cells

Yuelin Chen, Yuechun Shen, Ya Nie, Zhongxin Chen, Huang Wang, Huang Liao, Jun Li
Pages: 5097-5102
Published online on: 21 September 2017

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Article

Contrast‑enhanced ultrasound is better than magnetic resonance imaging in evaluating the short‑term results of microwave ablation treatment of uterine fibroids

Yan Zhang, Meiwu Zhang, Xiaoxiang Fan, Dafeng Mao
Pages: 5103-5108
Published online on: 21 September 2017

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Article

Application of positron emission tomography‑computed tomography in the diagnosis of pulmonary ground‑glass nodules

Lili Hu, Yuanwei Pan, Zhigang Zhou, Jianbo Gao
Pages: 5109-5113
Published online on: 22 September 2017

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Article

Expression of NF‑E2‑related factor 2 in a rat dural arteriovenous fistula model

Limin Dou, Wenhua Yu
Pages: 5114-5120
Published online on: 21 September 2017

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Article

Long non‑coding RNA ANRIL promotes the proliferation, migration and invasion of human osteosarcoma cells

Shuo Cheng, Tao Huang, Pengcheng Li, Wei Zhang, Zhihang Wang, Yao Chen
Pages: 5121-5125
Published online on: 18 September 2017

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Case Report

Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report

Kosuke Uemura, Momoko Isono, Katsunori Kagohashi, Ryuichi Hasegawa, Hiroaki Satoh
Pages: 5126-5128
Published online on: 21 September 2017

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Article

Oridonin enhances in vitro anticancer effects of lentinan in SMMC‑7721 human hepatoma cells through apoptotic genes

Tao Xu, Fa Jin, Keren Wu, Zhipeng Ye, Ning Li
Pages: 5129-5134
Published online on: 21 September 2017

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Article

Insect tea attenuates hydrochloric acid and ethanol‑induced mice acute gastric injury

Xin Zhao, Qiang Cheng, Yu Qian, Ruokun Yi, Lianjie Gu, Shanshan Wang, Jia‑Le Song
Pages: 5135-5142
Published online on: 22 September 2017

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Article

Antimicrobial resistance and prevalence of CvfB, SEK and SEQ genes among Staphylococcus aureus isolates from paediatric patients with bloodstream infections

Bing‑Shao Liang, Yan‑Mei Huang, Yin‑Shuang Chen, Hui Dong, Jia‑Liang Mai, Yong‑Qiang Xie, Hua‑Min Zhong, Qiu‑Lian Deng, Yan Long, Yi‑Yu Yang, Si‑Tang Gong, Zhen‑Wen Zhou
Pages: 5143-5148
Published online on: 22 September 2017

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Article

Inhibition of penile tunica albuginea myofibroblasts activity by adipose‑derived stem cells

Hesong Jiang, Qingqiang Gao, Xiaoyan Che, Leilei Zhu, Zheng Zhang, Yun Chen, Yutian Dai
Pages: 5149-5156
Published online on: 21 September 2017

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Article

Genetic variation of rs3811463 is associated with gestational diabetes mellitus susceptibility

Yun Liu, Zhi‑Ping Ge, Li‑Zhou Sun, Pei Tong, Hong‑Mei Lu
Pages: 5157-5162
Published online on: 22 September 2017

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Article

Renoprotective effects of emodin against diabetic nephropathy in rat models are mediated via PI3K/Akt/GSK‑3β and Bax/caspase‑3 signaling pathways

Danqing Jing, Hua Bai, Shinan Yin
Pages: 5163-5169
Published online on: 19 September 2017

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Article

Association between connexin 40 and potassium voltage‑gated channel subfamily A member 5 expression in the atrial myocytes of patients with atrial fibrillation

Fei Zhang, Yuhao Bian, Lei Huang, Wenbin Fan
Pages: 5170-5176
Published online on: 19 September 2017

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Article

Efficacy, safety and influencing factors of intra‑calf muscular injection of bone marrow mononuclear cells in the treatment of type 2 diabetes mellitus‑induced lower extremity vascular disease

Hui‑Min Zhou, Fan Liu, Ai‑Ge Yang, Yu‑Qing Guo, Ya‑Ru Zhou, Yong‑Quan Gu, Bao‑Yong Yan, Quan‑Hai Li
Pages: 5177-5185
Published online on: 22 September 2017

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Article Open Access

A novel effective chemical hemin for the treatment of acute carbon monoxide poisoning in mice

Hui‑Min Li, Ying‑Lu Shi, Di Wen, Huan‑Min Luo, Xi Lin, Fei Xiao
Pages: 5186-5192
Published online on: 21 September 2017

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Article

The role of aplysia ras homolog I in colon cancer cell invasion and adhesion

Jun Ouyang, Xiaohui Pan, Zecheng Hu
Pages: 5193-5199
Published online on: 18 September 2017

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Article

MicroRNA‑338‑3p targets SOX4 and inhibits cell proliferation and invasion of renal cell carcinoma

Zhigang Tong, Xianfeng Meng, Jinsong Wang, Lixin Wang
Pages: 5200-5206
Published online on: 21 September 2017

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Article

Susceptibility vessel sign predicts poor clinical outcome for acute stroke patients untreated by thrombolysis

Huiqin Liu, Wenli Mei, Yue Huang, Yongli Li, Zuzhi Chen, Dongdong Li, Hong Ye, Jiewen Zhang
Pages: 5207-5213
Published online on: 22 September 2017

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Article

ANXA1 affects cell proliferation, invasion and epithelial‑mesenchymal transition of oral squamous cell carcinoma

Ying‑Ming Wan, Jing Tian, Ling Qi, Li‑Mei Liu, Ning Xu
Pages: 5214-5218
Published online on: 20 September 2017

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Article

Glucagon‑like peptide‑1 potentiates glucose‑stimulated insulin secretion via the transient receptor potential melastatin 2 channel

Bo Pang, Sungjoon Kim, Daiqing Li, Zejun Ma, Bei Sun, Xiaona Zhang, Zhongming Wu, Liming Chen
Pages: 5219-5227
Published online on: 19 September 2017

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Article

Clinical value of urinary retinol‑binding protein in ascites due to cirrhosis

Yujing Xia, Jingjing Li, Sainan Li, Tong Liu, Yuqing Zhou, Qin Yin, Jianrong Wang, Wenxia Lu, Rong Zhang, Yuanyuan Zheng, Fan Wang, Jie Lu, Kan Chen, Weiqi Dai, Yingqun Zhou, Chuanyong Guo
Pages: 5228-5234
Published online on: 22 September 2017

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Journal Cover
January-2026 Volume 31 Issue 1

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Article Open Access

Adiposity indices and bone health amongst Malaysian adults: Evidence from a cross‑sectional study

Wenjian Zhao, Weizheng Zhang, Kok-Yong Chin, Xiaodong Ma, Hashwin Singh Tejpal Singh, Sophia Ogechi Ekeuku, Yuanzhong Wang, Xia Ji, Yang Guo, Sok Kuan Wong, Norliza Muhammad, Teh Rohaila Jamil, Saharuddin Ahmad
Article Number: 28
Published online on: 21 November 2025

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Ginsenoside Re attenuates homocysteine‑induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling

Shaolin Li, Chenge Zhao, Shengqin Yu, Kaijing Yang, Shuying Zhang, Sixu Liu
Article Number: 27
Published online on: 21 November 2025

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Case Report Open Access

Intussusception of the initial jejunum secondary to adenoma in the third and fourth portions of the duodenum: A case report

Lingbo Huo, Lixing Ma
Article Number: 26
Published online on: 21 November 2025

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Correction Open Access

[Corrigendum] Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β‑catenin signaling pathway

Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
Article Number: 25
Published online on: 19 November 2025

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Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

Shengbin Han, Jingzhe Xu, Chenchen Yu, Hongxi Guan, Shun Ding
Article Number: 24
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 23
Published online on: 17 November 2025

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Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

Jinqi Yan, Xiaohu Wang, Chen Liang
Article Number: 22
Published online on: 14 November 2025

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Review Open Access

Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

Mingxin He, Feng Chen, Xiaomin Xian, Zhi Guo
Article Number: 21
Published online on: 14 November 2025

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Article Open Access

Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

Yunching Lai, Xiaolei Chen, Hebing Zhou
Article Number: 20
Published online on: 10 November 2025

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Case Report Open Access

Diagnostic challenge of aneurysmal dermatofibroma mimicking cutaneous metastasis in a patient with lung cancer: A case report

Jong Yun Choi, Heeyang Park, Jangyoun Choi
Article Number: 19
Published online on: 10 November 2025

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Retraction Open Access

[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Article Number: 18
Published online on: 10 November 2025

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Article

Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study

Jeng-Yuan Yao, De-Tian-Yu Tzeng, Cai-Hong Feng, Gong-Man Xiao, Tian-Ni You, Ru-Yu Zheng
Article Number: 17
Published online on: 06 November 2025

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Case Report Open Access

Chronic maxillary sinusitis masquerading as a maxillary sinus neoplasm: A case report

Ji-Hyeon Oh, Seong-Gon Kim, Su-Young Kim
Article Number: 16
Published online on: 04 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
Article Number: 15
Published online on: 04 November 2025

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Article Open Access

A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

Jingqiao Li, Yipeng Yang, Xu Zhang, Dandan Zhang, Yadong Yu, Rong Chen, Wei Du
Article Number: 14
Published online on: 30 October 2025

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Case Report Open Access

Primary epithelioid angiomatous nodule of the vocal cord: A case report and literature review

Keda Li, Bin Huang, Lubing Cai, Mingqi Huang, Jianping Shi, Mingdi Jin, Ning Qian, Yongkang Guo
Article Number: 13
Published online on: 29 October 2025

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Case Report Open Access

Hepatic perivascular epithelioid cell tumor: A rare mesenchymal tumor with epithelioid features: A case report

Mahmoud Abbas, Benjamin Strücker, Mehmet Haluk Morgül, Andreas Pascher, Wolfgang Hartmann, Eva Wardelmann
Article Number: 12
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet

Lei Huang, Chao Ding, Xinmin Si
Article Number: 11
Published online on: 29 October 2025

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Article

Evaluation of total oxidant status/total antioxidant capacity and DNA damage in neonates with high lactate levels in umbilical cord blood gases

Burcu Cebeci, Aydemir Yalvaç, Derya Büyükkayhan, Dilek Kurnaz, Hakan Çakir, Murat Elevli
Article Number: 10
Published online on: 29 October 2025

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Case Report

Treatment of a mandibular molar with primary failure of eruption: A case report

Ming Guo, Weisheng Zhang
Article Number: 9
Published online on: 29 October 2025

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Effect of the water‑soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells

Xinghuanyu Xu, Lin Liu, Wenbai Zhang, Pu Xu
Article Number: 8
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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Retraction Open Access

[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

Xiao Ma, Jingjing Ma, Han Zhang, Xiaodong Jia, Tianrui Wang, Shanshan Ma, Yingze Zhang
Article Number: 4
Published online on: 21 October 2025

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Article Open Access

Epimedin C: A promising neuroprotective agent that can participate in mediating the JNK/Nrf2/HO‑1 signaling pathway to prevent neurodegenerative diseases

Chao Cong, Xuan-Ling Li, Guang-Yao Lin, Lian-Wei Xu
Article Number: 3
Published online on: 21 October 2025

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Article Open Access

Application of pleural effusion cell blocks for immunohistochemistry and EGFR gene mutation testing for advanced lung cancer

Shouxiang Zhao, Yuhong Liu, Tao Wang, Ying Li, Ze Chen, Xiaoshan Cai
Article Number: 2
Published online on: 21 October 2025

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Correction Open Access

[Corrigendum] Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility in vitro

Huan Wang, Tingtao Chen, Yidan Chen, Tao Luo, Buzhen Tan, Houyang Chen, Hongbo Xin
Article Number: 1
Published online on: 16 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Impact Factor: 2.3

Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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Case Report

A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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