Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
November-2017 Volume 14 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
November-2017 Volume 14 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report

  • Authors:
    • Kosuke Uemura
    • Momoko Isono
    • Katsunori Kagohashi
    • Ryuichi Hasegawa
    • Hiroaki Satoh
  • View Affiliations / Copyright

    Affiliations: Division of General Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310‑0015, Japan, Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310‑0015, Japan, Division of Intensive Care Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310‑0015, Japan
  • Pages: 5126-5128
    |
    Published online on: September 21, 2017
       https://doi.org/10.3892/etm.2017.5161
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Chlorine is a toxic inhalant and sources of exposure for individuals include accidental releases of chlorine vapor due to industrial or chemical transportation accidents. Inhalation of a large quantity of gas may cause circulatory and respiratory disorders or even mortality; however, the effects of a small amount of chlorine gas may be asymptomatic. The present case study presents a successfully treated 55‑year‑old male patient exposed to chlorine gas, resulting in bronchial damage and diffuse alveolar hemorrhage. Endobronchial and alveolar injuries were evaluated by direct observation using fiberoptic bronchoscopy (FB) and analyzing bronchoalveolar lavage fluid obtained by FB. Taking a precise medical history from the patient is crucial to correctly diagnose toxic gas inhalation. In addition, a timely and proper evaluation with chest imaging as well as FB may provide useful clinical information. Therefore, clinicians should consider performing FB if the circumstances permit.
View Figures

Figure 1

Figure 2

View References

1 

Becker M and Forrester M: Pattern of chlorine gas exposures reported to Texas poison control centers, 2000 through 2005. Tex Med. 104:51–57. 2008.

2 

Sexton JD and Pronchik DJ: Chlorine inhalation: The big picture. J Toxicol Clin Toxicol. 36:87–93. 1998. View Article : Google Scholar : PubMed/NCBI

3 

Winder C: The toxicology of chlorine. Environ Res. 85:105–114. 2001. View Article : Google Scholar : PubMed/NCBI

4 

White CW and Martin JG: Chlorine gas inhalation: Human clinical evidence of toxicity and experience in animal models. Proc Am Thorac Soc. 7:pp. 257–263. 2010; View Article : Google Scholar : PubMed/NCBI

5 

Kose A, Kose B, Açikalin A, Gunay N and Yildirim C: Myocardial infarction, acute ischemic stroke and hyperglycemia triggered by acute chlorine gas inhalation. Am J Emerg Med. 27:1022.e1–4. 2009. View Article : Google Scholar

6 

Li B, Jia L, Shao D, Liu H, Nie S, Tang W, Xu B, Hu Z and Sun H: Pneumomediastinum from acute inhalation of chlorine gas in 2 young patients. Am J Emerg Med. 29:357.e1–4. 2011. View Article : Google Scholar

7 

National Research Council, . Emergency and continuous exposure limits for selected airborne contaminants. 2. Washington, DC: National Academy Press. Committee on Toxicology, Board on Toxicology and Environmental Health Hazards, Commission on Life Sciences, National Research Council; pp. 5–110. 1984

8 

Kanne JP, Thoongsuwan N, Parimon T and Stern EJ: Trauma cases from Harborview Medical Center. Airway injury after acute chlorine exposure. AJR Am J Roentgenol. 186:232–233. 2006. View Article : Google Scholar : PubMed/NCBI

9 

Yarkın T, Adıgüzel N, Karakurt Z, Güngör G, Aksoy F and Baran R: Chlorine-induced extensive tracheobronchial necrosis concomitantly benzene-induced pancytopenia presented with severe pneumonia. Tuberk Toraks. 58:439–443. 2010.PubMed/NCBI

10 

Parimon T, Kanne JP and Pierson DJ: Acute inhalation injury with evidence of diffuse bronchiolitis following chlorine gas exposure at a swimming pool. Respir Care. 49:291–294. 2004.PubMed/NCBI

11 

Kilburn KH: Chlorine-induced damage documented by neurophysiological, neuropsychological, and pulmonary testing. Arch Environ Health. 55:31–37. 2000. View Article : Google Scholar : PubMed/NCBI

12 

Gautrin D, Leroyer C, Infante-Rivard C, Ghezzo H, Dufour JG, Girard D and Malo JL: Longitudinal assessment of airway caliber and responsiveness in workers exposed to chlorine. Am J Respir Crit Care Med. 160:1232–1237. 1999. View Article : Google Scholar : PubMed/NCBI

13 

Schwartz DA, Smith DD and Lakshminarayan S: The pulmonary sequelae associated with accidental inhalation of chlorine gas. Chest. 97:820–825. 1990. View Article : Google Scholar : PubMed/NCBI

14 

Donnelly SC and FitzGerald MX: Reactive airways dysfunction syndrome (RADS) due to chlorine gas exposure. Ir J Med Sci. 159:275–277. 1990. View Article : Google Scholar : PubMed/NCBI

15 

Akhavan A, Ajalloueyan M, Ghanei M and Moharamzad Y: Late laryngeal findings in sulfur mustard poisoning. Clin Toxicol (Phila). 47:142–144. 2009. View Article : Google Scholar : PubMed/NCBI

16 

Cohen MA and Guzzardi LJ: Inhalation of products of combustion. Ann Emerg Med. 12:6281983. View Article : Google Scholar : PubMed/NCBI

17 

Yamamoto R, Fujishima S and Ueno K: Two cases of delayed-onsetacute lung injury after chlorine gas exposure. JJAAM. 20:390–396. 2009.(In Japanese).

18 

Tian X, Tao H, Brisolara J, Chen J, Rando RJ and Hoyle GW: Acute lung injury induced by chlorine inhalation in C57BL/6 and FVB/N mice. Inhal Toxicol. 20:783–793. 2008. View Article : Google Scholar : PubMed/NCBI

19 

Babu RV, Cardenas V and Sharma G: Acute respiratory distress syndrome from chlorine inhalation during a swimming pool accident: A case report and review of the literature. J Intensive Care Med. 23:275–280. 2008. View Article : Google Scholar : PubMed/NCBI

20 

Batchinsky AI, Martini DK, Jordan BS, Dick EJ, Fudge J, Baird CA, Hardin DE and Cancio LC: Acute respiratory distress syndrome secondary to inhalation of chlorine gas in sheep. J Trauma. 60:944–957. 2006. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Uemura K, Isono M, Kagohashi K, Hasegawa R and Satoh H: Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report. Exp Ther Med 14: 5126-5128, 2017.
APA
Uemura, K., Isono, M., Kagohashi, K., Hasegawa, R., & Satoh, H. (2017). Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report. Experimental and Therapeutic Medicine, 14, 5126-5128. https://doi.org/10.3892/etm.2017.5161
MLA
Uemura, K., Isono, M., Kagohashi, K., Hasegawa, R., Satoh, H."Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report". Experimental and Therapeutic Medicine 14.5 (2017): 5126-5128.
Chicago
Uemura, K., Isono, M., Kagohashi, K., Hasegawa, R., Satoh, H."Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report". Experimental and Therapeutic Medicine 14, no. 5 (2017): 5126-5128. https://doi.org/10.3892/etm.2017.5161
Copy and paste a formatted citation
x
Spandidos Publications style
Uemura K, Isono M, Kagohashi K, Hasegawa R and Satoh H: Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report. Exp Ther Med 14: 5126-5128, 2017.
APA
Uemura, K., Isono, M., Kagohashi, K., Hasegawa, R., & Satoh, H. (2017). Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report. Experimental and Therapeutic Medicine, 14, 5126-5128. https://doi.org/10.3892/etm.2017.5161
MLA
Uemura, K., Isono, M., Kagohashi, K., Hasegawa, R., Satoh, H."Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report". Experimental and Therapeutic Medicine 14.5 (2017): 5126-5128.
Chicago
Uemura, K., Isono, M., Kagohashi, K., Hasegawa, R., Satoh, H."Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report". Experimental and Therapeutic Medicine 14, no. 5 (2017): 5126-5128. https://doi.org/10.3892/etm.2017.5161
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team