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Article

Insect tea attenuates hydrochloric acid and ethanol‑induced mice acute gastric injury

  • Authors:
    • Xin Zhao
    • Qiang Cheng
    • Yu Qian
    • Ruokun Yi
    • Lianjie Gu
    • Shanshan Wang
    • Jia‑Le Song
  • View Affiliations / Copyright

    Affiliations: Chongqing Collaborative Innovation Center for Functional Food, Chongqing University of Education, Chongqing 400067, P.R. China, Department of Nutrition and Food Hygiene, School of Public Health, Guilin Medical University, Guilin, Guangxi 541004, P.R. China, Chongqing Engineering Laboratory for Research and Development of Functional Food, Chongqing University of Education, Chongqing 400067, P.R. China
  • Pages: 5135-5142
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    Published online on: September 22, 2017
       https://doi.org/10.3892/etm.2017.5181
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Abstract

The aim of the present study was to investigate the protective effect of insect tea on HCl/ethanol‑induced gastric ulcers in ICR mice. The serum levels of vasoactive intestinal peptide, substance P, somatostatin, motilin and endothelin‑1 in mice were assessed using commercial kits and gastric tissues of superoxide dismutase (SOD, nitric oxide (NO) and malondialdehyde (MDA) were determined using western blot analysis Insect tea significantly reduced HCl/ethanol‑induced gastric juice secretion and increased the pH of gastric juice (P<0.05). Insect tea treatment signfiicantly increased vasoactive intestinal peptide and somatostatin, and significantly decreased motilin, substance P and endothelin levels in the serum (P<0.05). Treatment with insect tea was demonstrated to significantly increase levels of gastric SOD and NO and to reduce levels of MDA in the gastric ulcer mouse model (P<0.05). The gastric expression of inhibitor of nuclear factor‑κB (NF‑κB), epidermal growth factor (EGF), EGF receptor, neuronal nitric oxide synthase (nNOS), endothelial NOS, Mn‑SOD, Cu/Zn‑SOD and catalase was significantly increased in mice treated with inset tea compared with untreated model mice (P<0.05). Levels of NF‑κB, and inducible NOS were demonstrated to be decreased in mice treated with insect tea compared with untreated model mice (P<0.05). The results of the present study suggest that insect tea has a protective effect against HCl/ethanol‑induced gastric ulcers in ICR mice. This effect may be achieved via modulating serum neuropeptide levels, reducing gastric juice secretion, and modulating the inflammation‑ and antioxidant‑associated protein expressions in gastric tissue.
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View References

1 

Malfertheiner P, Chan FK and McColl KE: Peptic ulcer disease. Lancet. 374:1449–1461. 2009. View Article : Google Scholar : PubMed/NCBI

2 

Hsu CC, Hsu YC, Chang KH, Lee CY, Chong LW, Lin CL, Shang CS, Sung FC and Kao CH: Depression and the risk of peptic ulcer disease: A nationwide population-based study. Medicine (Baltimore). 94:e23332015. View Article : Google Scholar : PubMed/NCBI

3 

Gyires K: Neuropeptides and gastric mucosal homeostasis. Curr Top Med Chem. 4:63–74. 2004. View Article : Google Scholar : PubMed/NCBI

4 

Chen CY and Tsai CY: Ghrelin and motilin in the gastrointestinal system. Curr Pharm Des. 18:4755–4765. 2012. View Article : Google Scholar : PubMed/NCBI

5 

Long DM, Leonard AS, Story J and French LA: Hypothalamus and gastric ulceration: II. production of gastrointestinal ulceration by chronic hypothalamic Stimulation. Arch Neurol. 7:167–183. 1962. View Article : Google Scholar

6 

Mejia A and Kraft WK: Acid peptic diseases: Pharmacological approach to treatment. Expert Rev Clin Pharmacol. 2:295–314. 2009. View Article : Google Scholar : PubMed/NCBI

7 

Thomson AB, Sauve MD, Kassam N and Kamitakahara H: Safety of the long-term use of proton pump inhibitors. World J Gastroenterol. 16:2323–2330. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Zhao X, Wang R, Qian Y, Li G, Zhou Y and Sun P: In vivo preventive effects of insect tea on buccal mucosa cancer in ICR mice. J Cancer Res Ther. 10:651–657. 2014.PubMed/NCBI

9 

Xu L, Pan H, Lei Q, Xiao W, Peng Y and Xiao P: Insect tea, a wonderful work in the Chinese tea culture. Food Res Int. 53:629–635. 2013. View Article : Google Scholar

10 

Qian Y, Li GJ, Wang R, Zhou YL, Sun P and Zhao X: In vitro anticancer effects of insect tea in TCA8113 cells. J Cancer Res Ther. 10:1045–1051. 2014. View Article : Google Scholar : PubMed/NCBI

11 

Ao C: Scavenging effects of sandy-tea ethanol extract on super oxide anion and hydroxyl radical. Meat Res. 4:60–64. 2010.

12 

Zhao X, Wang Q, Qian Y and Song JL: Ilex kudingcha C.J. Tseng (Kudingcha) prevents HCl/ethanol-induced gastric injury in Sprague-Dawley rats. Mol Med Rep. 7:1613–1616. 2013. View Article : Google Scholar : PubMed/NCBI

13 

Wen L, Guo H, Li J, Yin R and Duan Z: Analyse of thebiological safety and major chemical components of Sanye insect tea. J Hunan Agric Univ. 22:574–579. 1996.

14 

Guo S, Xu W, Wen L, Huang Y and Wang F: The nutrient analysis and evaluation of Sanye insect-fermented tea. Chin Bull Entomol. 45:128–132. 2008.

15 

Beauchamp RD, Townsend CM, Singh P, Glass EJ and Thompson JC: Proglumide, a gastrin receptor antagonist, inhibits growth of colon cancer and enhances survival in mice. Ann Surg. 202:303–309. 1985. View Article : Google Scholar : PubMed/NCBI

16 

Brzozowski T, Konturek SJ, Sliwowski Z, Drozdowicz D, Zaczek M and Kedra D: Role of arginine, a substrate for nitric oxide-synthase, in gastroprotection and ulcer healing. J Gastroenterol. 32:442–452. 1997. View Article : Google Scholar : PubMed/NCBI

17 

Yatabe J, Saito F, Ishida I, Sato A, Hoshi M, Suzuki K, Kameda T, Ueno S, Yatabe MS, Watanabe T and Sanada H: Lower plasma arginine in enteral tube-fed patients with pressure ulcer and improved pressure ulcer healing after arginine supplementation by arginaid water. J Nutr Health Aging. 15:282–286. 2011. View Article : Google Scholar : PubMed/NCBI

18 

Desneves KJ, Todorovic BE, Cassar A and Crowe TC: Treatment with supplementary arginine, vitamin C and zinc in patients with pressure ulcers: A randomized controlled trial. Clin Nutr. 24:979–987. 2005. View Article : Google Scholar : PubMed/NCBI

19 

Zhenyukh O, Civantos E, Ruiz-Ortega M, Sánchez MS, Vázquez C, Peiró C, Egido J and Mas S: High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation. Free Radic Biol Med. 104:165–177. 2017. View Article : Google Scholar : PubMed/NCBI

20 

Zhang XJ, Chinkes DL and Wolfe RR: Leucine supplementation has an anabolic effect on proteins in rabbit skin wound and muscle. J Nutr. 134:3313–3318. 2004.PubMed/NCBI

21 

Alphin RS, Vokac VA, Gregory RL, Bolton PM and Tawes JW III: Role of intragastric pressure, pH and pepsin in gastric ulceration in the rat. Gastroenterology. 73:495–500. 1977.PubMed/NCBI

22 

Venables CW: Mucus, pepsin, and peptic ulcer. Gut. 27:233–238. 1986. View Article : Google Scholar : PubMed/NCBI

23 

Yamamoto O, Okada Y and Okabe S: Effects of a proton pump inhibitor, omeprazole, on gastric secretion and gastric and duodenal ulcers or erosions in rats. Dig Dis Sci. 29:394–401. 1984. View Article : Google Scholar : PubMed/NCBI

24 

Delaney JP, Cheng JW, Butler BA and Ritchie WP Jr: Gastric ulcer and regurgitation gastritis. Gut. 11:715–719. 1970. View Article : Google Scholar : PubMed/NCBI

25 

Guth PH: Pathogenesis of gastric mucosal injury. Annu Rev Med. 33:183–196. 1982. View Article : Google Scholar : PubMed/NCBI

26 

Sandor A, Kidd M, Lawton GP, Miu K, Tang LH and Modlin IM: Neurohormonal modulation of rat enterochromaffin-like cell histamine secretion. Gastroenterology. 110:1084–1092. 1996. View Article : Google Scholar : PubMed/NCBI

27 

Xie XZ, Zhao ZG, Qi DS and Wang ZM: Assay of gastrin and somatostatin in gastric antrum tissues of children with chronic gastritis and duodenal ulcer. World J Gastroenterol. 12:2288–2290. 2006. View Article : Google Scholar : PubMed/NCBI

28 

Geoghegan JG and Pappas TN: Central peptidergic control of gastric acid secretion. Gut. 40:164–166. 1997. View Article : Google Scholar : PubMed/NCBI

29 

Taché Y, Garrick T and Raybould H: Central nervous system action of peptides to influence gastrointestinal motor function. Gastroenterology. 98:517–528. 1990. View Article : Google Scholar : PubMed/NCBI

30 

Holzer P: Neural emergency system in the stomach. Gastroenterology. 114:823–839. 1998. View Article : Google Scholar : PubMed/NCBI

31 

Erin N, Türker S, Elpek Ö and Yıldırım B: Differential changes in Substance P, VIP as well as neprilysin levels in patients with gastritis or ulcer. Peptides. 35:218–224. 2012. View Article : Google Scholar : PubMed/NCBI

32 

Brown JC and Parkes CO: Effect on fundic pouch motor activity of stimulatory and inhibitory fractions separated from pancreozymin. Gastroenterology. 53:731–736. 1967.PubMed/NCBI

33 

Ruppin H, Domschke S, Domschke W, Wünsch E, Jaeger E and Demling L: Effects of 13-nle-motilin in man-inhibition of gastric evacuation and stimulation of pepsin secretion. Scand J Gastroenterol. 10:199–202. 1975.PubMed/NCBI

34 

Itoh Z, Honda R, Hiwatashi K, Takeuchi S, Aizawa I, Takayanagi R and Couch EF: Motilin-induced mechanical activity in the canine alimentary tract. Scand J Gastroenterol Suppl. 39:93–110. 1976.PubMed/NCBI

35 

Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K and Masaki T: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 332:411–415. 1988. View Article : Google Scholar : PubMed/NCBI

36 

Lazaratos S, Kashimura H, Nakahara A, Fukutomi H, Osuga T, Urushidani T, Miyauchi T and Goto K: Gastric ulcer induced by submucosal injection of ET-1: Role of potent vasoconstriction and intraluminal acid. Am J Physiol. 265:G491–G498. 1993.PubMed/NCBI

37 

Michida T, Kawano S, Masuda E, Kobayashi I, Nishimura Y, Tsujii M, Takei Y, Tsuji S, Nagano K, Fusamoto H, et al: Endothelin-1 in the gastric mucosa in stress ulcers of critically ill patients. Am J Gastroenterol. 92:1177–1181. 1997.PubMed/NCBI

38 

Masuda E, Kawano S, Nagano K, Tsuji S, Takei Y, Hayashi N, Tsujii M, Oshita M, Michida T, Kobayashi I, et al: Role of endogenous endothelin in pathogenesis of ethanol-induced gastric mucosal injury in rats. Am J Physiol. 265:G474–G481. 1993.PubMed/NCBI

39 

Lloyd KC, Wang J, Aurang K, Grönhed P, Coy DH and Walsh JH: Activation of somatostatin receptor subtype 2 inhibits acid secretion in rats. Am J Physiol. 268:G102–G106. 1995.PubMed/NCBI

40 

Aurang K, Wang J and Lloyd K: Somatostatin inhibition of acid and histamine release by activation of somatostatin receptor subtype 2 receptors in rats. J Pharmacol Exp Ther. 281:245–252. 1997.PubMed/NCBI

41 

Martinez V, Curi AP, Torkian B, Schaeffer JM, Wilkinson HA, Walsh JH and Taché Y: High basal gastric acid secretion in somatostatin receptor subtype 2 knockout mice. Gastroenterology. 114:1125–1132. 1998. View Article : Google Scholar : PubMed/NCBI

42 

Saadé NE, Abdallah LE, Barada KA, Atweh SF and Nassar CF: Effects of intracerebral injections of VIP on jejunal alanine absorption and gastric acid secretion in rats. Regul Pept. 55:269–276. 1995. View Article : Google Scholar : PubMed/NCBI

43 

Nassar CF, Abdallah LE, Barada KA, Atweh SF and Saadé NE: Effects of intravenous vasoactive intestinal peptide injection on jejunal alanine absorption and gastric acid secretion in rats. Regul Pept. 55:261–267. 1995. View Article : Google Scholar : PubMed/NCBI

44 

Yoshikawa T, Ueda S, Naito Y, Takahashi S, Oyamada H, Morita Y, Yoneta T and Kondo M: Role of oxygen-derived free radicals in gastric mucosal injury induced by ischemia or ischemia-reperfusion in rats. Free Radic Res Commun. 7:285–291. 1989. View Article : Google Scholar : PubMed/NCBI

45 

Yoshikawa T, Naito Y, Ueda S, Oyamada H, Takemura T, Yoshida N, Sugino S and Kondo M: Role of oxygen-derived free radicals in the pathogenesis of gastric mucosal lesions in rats. J Clin Gastroenterol. 12 Suppl 1:S65–S71. 1990. View Article : Google Scholar : PubMed/NCBI

46 

Yoshikawa T, Naito Y, Kishi A, Tomii T, Kaneko T, Iinuma S, Ichikawa H, Yasuda M, Takahashi S and Kondo M: Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats. Gut. 34:732–737. 1993. View Article : Google Scholar : PubMed/NCBI

47 

Itoh M and Guth PH: Role of oxygen-derived free radicals in hemorrhagic shock-induced gastric lesions in the rat. Gastroenterology. 88:1162–1167. 1985. View Article : Google Scholar : PubMed/NCBI

48 

Jung HK, Lee KE, Chu SH and Yi SY: Reactive oxygen species activity, mucosal lipoperoxidation and glutathione in Helicobacter pylori-infected gastric mucosa. J Gastroenterol Hepatol. 16:1336–1340. 2001. View Article : Google Scholar : PubMed/NCBI

49 

Akiba Y, Nakamura M, Mori M, Suzuki H, Oda M, Kimura H, Miura S, Tsuchiya M and Ishii H: Inhibition of inducible nitric oxide synthase delays gastric ulcer healing in the rat. J Clin Gastroenterol. 27 Suppl 1:S64–S73. 1998. View Article : Google Scholar : PubMed/NCBI

50 

Rajnakova A, Goh PM, Chan ST, Ngoi SS, Alponat A and Moochhala S: Expression of differential nitric oxide synthase isoforms in human normal gastric mucosa and gastric cancer tissue. Carcinogenesis. 18:1841–1845. 1997. View Article : Google Scholar : PubMed/NCBI

51 

Barrachina M, Esplugues J, Martinezcuesta M, Calatayud S, Bello R and Wittle B: Nitric-oxide donors preferentially inhibit neuronally stimulated gastric-acid secretion. Gastroenterology. 47:1994.

52 

Takeuchi K, Ohuchi T and Okabe S: Nitric-oxide mediates inhibition of gastric-acid secretion in the damaged stomach-interaction with endogenous prostaglandins. Gastroenterology. 1921994.

53 

Ma L and Wallace JL: Endothelial nitric oxide synthase modulates gastric ulcer healing in rats. Am J Physiol Gastrointest Liver Physiol. 279:G341–G346. 2000.PubMed/NCBI

54 

Guo JS, Cho CH, Wang WP, Shen XZ, Cheng CL and Koo MW: Expression and activities of three inducible enzymes in the healing of gastric ulcers in rats. World J Gastroenterol. 9:1767–1771. 2003. View Article : Google Scholar : PubMed/NCBI

55 

Gambhir S, Vyas D, Hollis M, Aekka A and Vyas A: Nuclear factor kappa B role in inflammation-associated gastrointestinal malignancies. World J Gastroenterol. 21:3174–3183. 2015. View Article : Google Scholar : PubMed/NCBI

56 

Yanai A, Maeda S, Shibata W, Hikiba Y, Sakamoto K, Nakagawa H, Ohmae T, Hirata Y, Ogura K, Muto S, et al: Activation of IKappaB kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils. Infect Immun. 76:781–787. 2008. View Article : Google Scholar : PubMed/NCBI

57 

Brzozowski T, Konturek SJ, Majka J, Dembinski A and Drozdowicz D: Epidermal growth factor, polyamines, and prostaglandins in healing of stress-induced gastric lesions in rats. Dig Dis Sci. 38:276–283. 1993. View Article : Google Scholar : PubMed/NCBI

58 

Konturek JW, Bielanski W, Konturek SJ, Bogdal J and Oleksy J: Distribution and release of epidermal growth factor in man. Gut. 30:1194–1200. 1989. View Article : Google Scholar : PubMed/NCBI

59 

Reeves J, Richards R and Cooke T: The effects of intracolonic EGF on mucosal growth and experimental carcinogenesis. Br J Cancer. 63:223–226. 1991. View Article : Google Scholar : PubMed/NCBI

60 

Challacombe DN and Wheeler EE: Trophic action of epidermal growth factor on human duodenal mucosa cultured in vitro. Gut. 32:991–993. 1991. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhao X, Cheng Q, Qian Y, Yi R, Gu L, Wang S and Song JL: Insect tea attenuates hydrochloric acid and ethanol‑induced mice acute gastric injury. Exp Ther Med 14: 5135-5142, 2017.
APA
Zhao, X., Cheng, Q., Qian, Y., Yi, R., Gu, L., Wang, S., & Song, J. (2017). Insect tea attenuates hydrochloric acid and ethanol‑induced mice acute gastric injury. Experimental and Therapeutic Medicine, 14, 5135-5142. https://doi.org/10.3892/etm.2017.5181
MLA
Zhao, X., Cheng, Q., Qian, Y., Yi, R., Gu, L., Wang, S., Song, J."Insect tea attenuates hydrochloric acid and ethanol‑induced mice acute gastric injury". Experimental and Therapeutic Medicine 14.5 (2017): 5135-5142.
Chicago
Zhao, X., Cheng, Q., Qian, Y., Yi, R., Gu, L., Wang, S., Song, J."Insect tea attenuates hydrochloric acid and ethanol‑induced mice acute gastric injury". Experimental and Therapeutic Medicine 14, no. 5 (2017): 5135-5142. https://doi.org/10.3892/etm.2017.5181
Copy and paste a formatted citation
x
Spandidos Publications style
Zhao X, Cheng Q, Qian Y, Yi R, Gu L, Wang S and Song JL: Insect tea attenuates hydrochloric acid and ethanol‑induced mice acute gastric injury. Exp Ther Med 14: 5135-5142, 2017.
APA
Zhao, X., Cheng, Q., Qian, Y., Yi, R., Gu, L., Wang, S., & Song, J. (2017). Insect tea attenuates hydrochloric acid and ethanol‑induced mice acute gastric injury. Experimental and Therapeutic Medicine, 14, 5135-5142. https://doi.org/10.3892/etm.2017.5181
MLA
Zhao, X., Cheng, Q., Qian, Y., Yi, R., Gu, L., Wang, S., Song, J."Insect tea attenuates hydrochloric acid and ethanol‑induced mice acute gastric injury". Experimental and Therapeutic Medicine 14.5 (2017): 5135-5142.
Chicago
Zhao, X., Cheng, Q., Qian, Y., Yi, R., Gu, L., Wang, S., Song, J."Insect tea attenuates hydrochloric acid and ethanol‑induced mice acute gastric injury". Experimental and Therapeutic Medicine 14, no. 5 (2017): 5135-5142. https://doi.org/10.3892/etm.2017.5181
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