|
1
|
Miyamoto S, Yonenobu K and Ono K:
Experimental cervical spondylosis in the mouse. Spine (Phila Pa
1976). 16(10 Suppl): S495–S500. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Mern DS, Beierfuss A, Thome C and Hegewald
AN: Enhancing human nucleus pulposus cells for biological treatment
approaches of degenerative intervertebral disc diseases: A
systematic review. J Tissue Eng Regenerative Med. 8:925–936. 2014.
View Article : Google Scholar
|
|
3
|
Wuertz K and Haglund L: Inflammatory
mediators in intervertebral disk degeneration and discogenic pain.
Global Spine J. 3:175–184. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Shamji MF, Setton LA, Jarvis W, So S, Chen
J, Jing L, Bullock R, Isaacs RE, Brown C and Richardson WJ:
Proinflammatory cytokine expression profile in degenerated and
herniated human intervertebral disc tissues. Arthritis Rheum.
62:1974–1982. 2010.PubMed/NCBI
|
|
5
|
Akyol S, Eraslan BS, Etyemez H, Tanriverdi
T and Hanci M: Cataboliccytokine expressions in patients with
degenerative disc disease. Turk Neurosurg. 20:492–499.
2010.PubMed/NCBI
|
|
6
|
Le Maitre CL, Freemont AJ and Hoyland JA:
The role of interleukin-1 in the pathogenesis of human
intervertebral disc degeneration. Arthritis Res Ther. 7:R732–R745.
2005. View
Article : Google Scholar : PubMed/NCBI
|
|
7
|
Le Maitre CL, Hoyland JA and Freemont AJ:
Catabolic cytokine expression in degenerate and herniated human
intervertebral discs: IL-1beta and TNFalpha expression profile.
Arthritis Res Ther. 9:R772007. View
Article : Google Scholar : PubMed/NCBI
|
|
8
|
Risbud MV and Shapiro IM: Role of
cytokines in intervertebral disc degeneration: Pain and disc
content. Nat Rev Rheumatol. 10:44–56. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Sutovsky J, Benco M, Sutovska M, Kocmalova
M, Pappova L, Miklusica J, Frano A and Kurca E: Cytokine and
chemokine profile changes in patients with lower segment lumbar
degenerative spondylolisthesis. Int J Surg. 43:163–170. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Zhang Y, Zhao Y, Li J, Wang S, Liu Y, Nie
L and Cheng L: Interleukin-9 Promotes TNF-α and PGE2 release in
human degenerated intervertebral disc tissues. Spine (Phila Pa
1976). 41:1631–1640. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Schroeder GD, Markova DZ, Koerner JD, Rihn
JA, Hilibrand AS, Vaccaro AR, Anderson DG and Kepler CK: Are Modic
changes associated with intervertebral disc cytokine profiles?
Spine J. 17:129–134. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Kuelling FA, Foley KT, Liu JJ, Liebenberg
E, Sin AH, Matsukawa A and Lotz JC: The anabolic effect of
plasma-mediated ablation on the intervertebral disc: Stimulation of
proteoglycan and interleukin-8 production. Spine J. 14:2479–2487.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Wang YJ, Shi Q, Lu WW, Cheung KC, Darowish
M, Li TF, Dong YF, Zhou CJ, Zhou Q, Hu ZJ, et al: Cervical
intervertebral disc degeneration induced by unbalanced dynamic and
static forces: A novel in vivo rat model. Spine (Phila Pa 1976).
31:1532–1538. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Dinarello CA: Immunological and
inflammatory functions of the interleukin-1 family. Annu Rev
Immunol. 27:1–550. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Dinarello CA: Interleukin-1 in the
pathogenesis and treatment of inflammatory diseases. Blood.
117:3720–3732. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Rosenzweig JM, Lei J and Burd I:
Interleukin-1 receptor blockade in perinatal brain injury. Front
Pediatr. 2:1082014. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Yang W, Yu XH, Wang C, He WS, Zhang SJ,
Yan YG, Zhang J, Xiang YX and Wang WJ: Interleukin-1β in
intervertebral disk degeneration. Clinica Chimica Acta. 450:1–272.
2015. View Article : Google Scholar
|
|
18
|
Smith LJ, Chiaro JA, Nerurkar NL, Cortes
DH, Horava SD, Hebela NM, Mauck RL, Dodge GR and Elliott DM:
Nucleus pulposus cells synthesize a functional extracellular matrix
and respond to inflammatory cytokine challenge following long-term
agarose culture. Eur Cell Mater. 22:291–301. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Sainoh T, Orita S, Miyagi M, Inoue G,
Kamoda H, Ishikawa T, Yamauchi K, Suzuki M, Sakuma Y, Kubota G, et
al: Single intradiscal administration of the tumor necrosis
factor-alpha inhibitor, etanercept, for patients with discogenic
low back pain. Pain Med. 17:40–45. 2016.PubMed/NCBI
|
|
20
|
Séguin CA, Pilliar RM, Roughley PJ and
Kandel RA: Tumor necrosis factor-alpha modulates matrix production
and catabolism in nucleus pulposus tissue. Spine (Phila Pa 1976).
30:1940–1948. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Purmessur D, Freemont AJ and Hoyland JA:
Expression and regulation of neurotrophins in the nondegenerate and
degenerate human intervertebral disc. Arthritis Res Ther.
10:R992008. View
Article : Google Scholar : PubMed/NCBI
|
|
22
|
Lai A, Moon A, Purmessur D, Skovrlj B,
Laudier DM, Winkelstein BA, Cho SK, Hecht AC and Iatridis JC:
Annular puncture with tumor necrosis factor-alpha injection
enhances painful behavior with disc degeneration in vivo. Spine J.
16:420–431. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Lee S, Moon CS, Sul D, Lee J, Bae M, Hong
Y, Lee M, Choi S, Derby R, Kim BJ, et al: Comparison of growth
factor and cytokine expression in patients with degenerated disc
disease and herniated nucleus pulposus. Clin Biochem. 42:1504–1511.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Burke JG, Watson RW, McCormack D, Dowling
FE, Walsh MG and Fitzpatrick JM: Intervertebral discs which cause
low back pain secrete high levels of proinflammatory mediators. J
Bone Joint Surg Br. 84:196–201. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Starbeck-Miller GR, Xue HH and Harty JT:
IL-12 and type I interferon prolong the division of activated CD8 T
cells by maintaining high-affinity IL-2 signaling in vivo. J Exp
Med. 211:1–120. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Garcia K, Sun Z, Mattson E, Li L, Smyth K
and Xiao Z: IL-12 is required for mTOR regulation of memory CTLs
during viral infection. Genes Immun. 15:413–423. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Abdi K and Singh NJ: Singh Making many
from few: IL-12p40 as a model for the combinatorial assembly of
heterodimeric cytokines. Cytokine. 76:53–57. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Akyol S, Eraslan BS, Etyemez H, Tanriverdi
T and Hanci M: Catabolic cytokine expressions in patients with
degenerative disc disease. Turk Neurosurg. 20:492–499.
2010.PubMed/NCBI
|
|
29
|
Lin WP, Lin JH, Chen XW, Wu CY, Zhang LQ
and Lai JM: Interleukin-10 promoter polymorphisms associated with
susceptibility to lumbar disc degeneration in a Chinese cohort.
Genetics Mol Res. 10:1719–1727. 2011. View Article : Google Scholar
|
|
30
|
Holm S, Mackiewicz Z, Holm AK, Konttinen
YT, Kouri VP, Indahl A and Salo J: Pro-inflammatory, pleiotropic,
and anti-inflammatory TNF-alpha, IL-6, and IL-10 in experimental
porcine intervertebral disk degeneration. Vet Pathol. 46:1292–1300.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Li W, Liu T, Wu L, Chen C, Jia Z, Bai X
and Ruan D: Blocking the function of inflammatory cytokines and
mediators by using IL-10 and TGF-β: A potential biological
immunotherapy for intervertebral disc degeneration in a beagle
model. Int J Mol Sci. 15:17270–17283. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Maltman J, Pragnell IB and Graham GJ:
Specificity and reciprocity in the interactions between TGF-beta
and macrophage inflammatory protein-1 alpha. J Immunol.
156:1566–1571. 1996.PubMed/NCBI
|
|
33
|
Zhen G and Cao X: Targeting TGFβ signaling
in subchondral bone and articular cartilage homeostasis. Trends
Pharmacol Sci. 35:227–236. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Nishida K, Kang JD, Gilbertson LG, Moon
SH, Suh JK, Vogt MT, Robbins PD and Evans CH: Modulation of the
biologic activity of the rabbit intervertebral disc by gene
therapy: An in vivo study of adenovirus-mediated transfer of the
human transforming growth factor beta 1 encoding gene. Spine (Phila
Pa 1976). 24:2419–2425. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Illien-Jünger S, Lu Y, Purmessur D, Mayer
JE, Walter BA, Roughley PJ, Qureshi SA, Hecht AC and Iatridis JC:
Detrimental effects of discectomy on intervertebral disc biology
can be decelerated by growth factor treatment during surgery - a
large animal organ culture mode. Spine J. 14:2724–2732. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Cho H, Lee S, Park SH, Huang J, Hasty KA
and Kim SJ: Synergistic effect of combined growth factors in
porcine intervertebral disc degeneration. Connect Tissue Res.
54:181–186. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Abbott RD, Purmessur D, Monsey RD,
Brigstock DR, Laudier DM and Iatridis JC: Degenerative grade
affects the responses of human nucleus pulposus cells to link-N,
CTGF, and TGFβ3. J Spinal Disord Tech. 26:E86–E94. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Kishimoto T, Akira S, Narazaki M and Taga
T: Interleukin-6 family of cytokines and gp130. Blood.
86:1243–1254. 1995.PubMed/NCBI
|
|
39
|
Gruol DL: IL-6 regulation of synaptic
function in the CNS. Neuropharmacology. 96:42–54. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Gruol DL, Puro A, Hao C, Blakely P,
Janneke E and Vo K: Neuroadaptive changes in cerebellar neurons
induced by chronic exposure to IL-6. J Neuroimmunol. 239:28–36.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Sainoh T, Orita S, Miyagi M, Sakuma Y,
Yamauchi K, Suzuki M, Kubota G, Oikawa Y, Inage K, Sato J, et al:
Interleukin-6 and interleukin-6 receptor expression, localization
and involvement in pain-sensing neuron activation in a mouse
intervertebral disc injury mode. J Orthop Res. 33:1508–1514. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Miyagi M, Ishikawa T, Orita S, Eguchi Y,
Kamoda H, Arai G, Suzuki M, Inoue G, Aoki Y, Toyone T, et al: Disk
injury in rats produces persistent increases in pain-related
neuropeptides in dorsal root ganglia and spinal cord glia but only
transient increases in inflammatory mediators: Pathomechanism of
chronic diskogenic low back pain. Spine (PhilaPa 1976).
36:2260–2266. 2011. View Article : Google Scholar
|
|
43
|
Xiang YJ, Shen XH, Shen Z, et al: Local
inflammatory cytokine changes in degenerative vertebal discs in
patients with cervical spondylotic myelopathy. Acad J Sec Mil Univ.
24:788–790. 2003.
|
