Recurrent primary hyperoxaluria type 2 leads to early post‑transplant renal function loss: A case report

Liu,Si; Gao,Baoshan; Wang,Gang; Wang,Weigang; Lian,Xin; Wu,Shan; Yu,Jinyu; Fu,Yaowen; Zhou,Honglan

doi:10.3892/etm.2018.5841

April-2018 Volume 15 Issue 4

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April-2018 Volume 15 Issue 4

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Case Report Open Access

Recurrent primary hyperoxaluria type 2 leads to early post‑transplant renal function loss: A case report

Authors:
- Si Liu
- Baoshan Gao
- Gang Wang
- Weigang Wang
- Xin Lian
- Shan Wu
- Jinyu Yu
- Yaowen Fu
- Honglan Zhou
View Affiliations / Copyright

Affiliations: Department of Urology, Transplant Center, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China

Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 3169-3172
|
Published online on: February 7, 2018

https://doi.org/10.3892/etm.2018.5841
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Abstract

Primary hyperoxaluria type 2 is a rare autosomal recessive disorder caused by glyoxylate reductase/hydroxypyruvate reductase deficiency and characterized by recurrent episodes of nephrolithiasis and nephrocalcinosis. Herein, we describe a case of primary hyperoxaluria type 2 in a 33‑year‑old man who failed to respond to conventional therapies; thus renal transplantation was performed. This case demonstrated that, although primary hyperoxaluria type 2 is rare, hyperoxaluria should be suspected and blood oxalate and stone component be examined in patients with recurrent episodes of nephrolithiasis, particularly in those who are unresponsive to conventional therapies. Combined liver‑kidney transplant may be required as kidney transplant alone is not likely to be successful.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Recurrent primary hyperoxaluria type 2 leads to early post‑transplant renal function loss: A case report

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