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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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April-2018 Volume 15 Issue 4

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Review Open Access

Current diagnostic imaging of pheochromocytomas and implications for therapeutic strategy (Review)

Filip Čtvrtlík, Pavel Koranda, Jan Schovánek, Jozef Škarda, Igor Hartmann, Zbyněk Tüdös
Pages: 3151-3160
Published online on: 14 February 2018

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Review

The importance of handling high-value biologicals: Physico-chemical instability and immunogenicity of monoclonal antibodies (Review)

Tomislav Laptoš, Jasna Omersel
Pages: 3161-3168
Published online on: 31 January 2018

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Case Report Open Access

Recurrent primary hyperoxaluria type 2 leads to early post‑transplant renal function loss: A case report

Si Liu, Baoshan Gao, Gang Wang, Weigang Wang, Xin Lian, Shan Wu, Jinyu Yu, Yaowen Fu, Honglan Zhou
Pages: 3169-3172
Published online on: 07 February 2018

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Article Open Access

DNA methylation is a common molecular alteration in colorectal cancer cells and culture method has no influence on DNA methylation

Shibao Wang, Yinghui Huang, Xupeng Mu, Tianyang Qi, Sha Qiao, Zhenxia Lu, Hongjun Li
Pages: 3173-3180
Published online on: 30 January 2018

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Article Open Access

MicroRNA-383 upregulation protects against propofol-induced hippocampal neuron apoptosis and cognitive impairment

Xinlei Wang, Guoyou Ding, Wei Lai, Shiwen Liu, Jun Shuai
Pages: 3181-3188
Published online on: 05 February 2018

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Article Open Access

Human fibroblast growth factor-21 serves as a predictor and prognostic factor in patients with hepatitis B cirrhosis combined with adrenal insufficiency

Jian Zhang, Junhong Li, Junwei Ma, Hongxin Wang, Yin Yi
Pages: 3189-3196
Published online on: 06 February 2018

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Article Open Access

Expression and phosphorylation of FOXO1 influences cell proliferation and apoptosis in the gastrointestinal stromal tumor cell line GIST-T1

Tao Wang, Hui Zhao, Hua Gao, Changming Zhu, Yao Xu, Liping Bai, Junbo Liu, Feng Yan
Pages: 3197-3202
Published online on: 08 February 2018

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Article Open Access

GEMALS: A promising therapy for amyotrophic lateral sclerosis

Michel Geffard, Arturo Mangas, Denis Bedat, Rafael Coveñas
Pages: 3203-3210
Published online on: 14 February 2018

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Article Open Access

Identification of dysregulated modules based on network entropy in type 1 diabetes

Yan Zheng, Liwei Liu, Jifeng Ye
Pages: 3211-3214
Published online on: 29 January 2018

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Article Open Access

A morphological and biochemical evaluation of the effects of quercetin on experimental sciatic nerve damage in rats

Sibel Türedi, Esin Yuluğ, Ahmet Alver, Akın Bodur, İmran İnce
Pages: 3215-3224
Published online on: 31 January 2018

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Article Open Access

Finite element analysis of compression fractures at the thoracolumbar junction using models constructed from medical images

Daisuke Nakashima, Tsukasa Kanchiku, Norihiro Nishida, Saki Ito, Junji Ohgi, Hidenori Suzuki, Yasuaki Imajo, Masahiro Funaba, Xian Chen, Toshihiko Taguchi
Pages: 3225-3230
Published online on: 07 February 2018

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Article Open Access

Thymosin α1 treatment reduces hepatic inflammation and inhibits hepatocyte apoptosis in rats with acute liver failure

Xueliang Yang, Yunru Chen, Jian Zhang, Tiantian Tang, Ying Kong, Feng Ye, Xi Zhang, Xiaojing Liu, Shumei Lin
Pages: 3231-3238
Published online on: 07 February 2018

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Article Open Access

MicroRNA-215 suppresses the proliferation, migration and invasion of non-small cell lung carcinoma cells through the downregulation of matrix metalloproteinase-16 expression

Yuanshan Yao, Haibo Shen, Yinjie Zhou, Zhenhua Yang, Tianjun Hu
Pages: 3239-3246
Published online on: 14 February 2018

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Article Open Access

Clinical significance of microRNA-449a in hepatocellular carcinoma with microarray data mining together with initial bioinformatics analysis

Xia Yang, Han‑Lin Wang, Hai‑Wei Liang, Liang Liang, Dong‑Yue Wen, Rui Zhang, Gang Chen, Dan‑Ming Wei
Pages: 3247-3258
Published online on: 05 February 2018

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Article Open Access

Application of 3D visualization and 3D printing technology on ERCP for patients with hilar cholangiocarcinoma

Yan Yang, Zhongyin Zhou, Rong Liu, Lu Chen, Hongyu Xiang, Na Chen
Pages: 3259-3264
Published online on: 02 February 2018

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Article Open Access

Efficient delivery of recombinant human bone morphogenetic protein (rhBMP‑2) with dextran sulfate‑chitosan microspheres

Yuan‑Jun Xia, Hong Xia, Ling Chen, Qing‑Shui Ying, Xiang Yu, Li‑Hua Li, Jian‑Hua Wang, Ying Zhang
Pages: 3265-3272
Published online on: 07 February 2018

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Article Open Access

Comprehensive analysis of differential expression profiles reveals potential biomarkers associated with the cell cycle and regulated by p53 in human small cell lung cancer

Zhong Ni, Xiting Wang, Tianchen Zhang, Linlin Li, Jianxue Li
Pages: 3273-3282
Published online on: 02 February 2018

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Article Open Access

Effective robotic assistive pattern of treadmill training for spinal cord injury in a rat model

Bo‑Lun Zhao, Wen‑Tao Li, Xiao‑Hua Zhou, Su‑Qian Wu, Hong‑Shi Cao, Zhu‑Ren Bao, Li‑Bin An
Pages: 3283-3294
Published online on: 31 January 2018

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Article Open Access

Expression of DNA‑dependent protein kinase catalytic subunit in laryngeal squamous cell carcinoma and its importance

Jian‑Song Sun, Xiu‑Hai Yang
Pages: 3295-3301
Published online on: 01 February 2018

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Article

Protective function of Bu Shen Huo Xue formula on the immunity of B6AF1 mice with experimental autoimmune premature ovarian failure

Peijuan Wang, Yan Lu, Si Chen, Yue Chen, Chunping Hu, Yawei Zuo
Pages: 3302-3310
Published online on: 29 January 2018

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Article Open Access

Non-invasive cell tracking of SPIO labeled cells in an intrinsic regenerative environment: The axolotl limb

Henrik Lauridsen, Casper Bindzus Foldager, Line Hansen, Michael Pedersen
Pages: 3311-3319
Published online on: 14 February 2018

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Article Open Access

The role of inhibition by phosphocitrate and its analogue in chondrocyte differentiation and subchondral bone advance in Hartley guinea pigs

Yubo Sun, Alex J. Kiraly, Michael Cox, David R. Mauerhan, Edward N. Hanley
Pages: 3320-3328
Published online on: 07 February 2018

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Article Open Access

Non-invasive predictive model for hepatic venous pressure gradient based on a 3-dimensional computed tomography volume rendering technology

Yujen Tseng, Lili Ma, Tiancheng Luo, Xiaoqing Zeng, Na Li, Yichao Wei, Ji Zhou, Feng Li, Shiyao Chen
Pages: 3329-3335
Published online on: 30 January 2018

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Article Open Access

Positive association between leptin serum levels and disease activity on endoscopy in inflammatory bowel disease: A case-control study

Fabiola Trejo‑Vazquez, Idalia Garza‑Veloz, Gabriela Alejandra Villela‑Ramirez, Yolanda Ortiz‑Castro, Panfilo Mauricio‑Saucedo, Edith Cardenas‑Vargas, Mariana Diaz‑Baez, Miguel A. Cid‑Baez, Rodrigo Castañeda‑Miranda, Jose Manuel Ortiz‑Rodriguez, Luis Octavio Solis‑Sanchez, Margarita L. Martinez‑Fierro
Pages: 3336-3344
Published online on: 05 February 2018

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Article Open Access

Nimotuzumab enhances the sensitivity of non-small cell lung cancer cells to tumor necrosis factor-α by inhibiting the nuclear factor-кB signaling pathway

Jing Zhu, Ying Xin, Xiaoliang Liu, Ying Wang, Ying Liu
Pages: 3345-3351
Published online on: 12 February 2018

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Article Open Access

Application effect of single balloon catheters in labor induction of pregnant women in late-term pregnancy and their influences on stress and inflammatory responses

Yun Chai, Miaomiao Qu, Meng Jin
Pages: 3352-3356
Published online on: 18 January 2018

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Article Open Access

Expression of serum AMPD1 in thyroid carcinoma and its clinical significance

Tianzhou Zha, Haorong Wu
Pages: 3357-3361
Published online on: 12 February 2018

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Article Open Access

Molecular differences between mature and immature dental pulp cells: Bioinformatics and preliminary results

Long Chen, Yifeng Jiang, Zhen Du
Pages: 3362-3368
Published online on: 07 February 2018

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Article Open Access

Expression of microRNAs in the serum exosomes of methamphetamine-dependent rats vs. ketamine-dependent rats

Hancheng Li, Chan Li, Yuting Zhou, Chaohua Luo, Jingying Ou, Jing Li, Zhixian Mo
Pages: 3369-3375
Published online on: 30 January 2018

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Article Open Access

Effect of TLR4/MyD88 signaling pathway on sepsis-associated acute respiratory distress syndrome in rats, via regulation of macrophage activation and inflammatory response

Shujun Zhou, Gui Wang, Wenbin Zhang
Pages: 3376-3384
Published online on: 30 January 2018

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Article Open Access

Therapeutic effects of Hedyotis diffusa Willd in a COPD mouse model challenged with LPS and smoke

Renping Liu, Peihong Wang, Caiqing Wu, Juan Chen, Chengxin Li, Yongtao Xie, Qi Wang, Jianming Liu, Huan He, Jing Zhu
Pages: 3385-3391
Published online on: 08 February 2018

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Article Open Access

ASAP1 gene polymorphisms are associated with susceptibility to tuberculosis in a Chinese Xinjiang Muslim population

Xianhua Wang, Aiguo Ma, Xiuxia Han, Aishan Litifu, Feng Xue
Pages: 3392-3398
Published online on: 25 January 2018

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Article Open Access

Association between HLA gene polymorphism and cutaneous adverse reactions caused by antiepileptic drugs

Jingang Zhang, Xinrui Li, Yuanyuan Su, Min Sun, Junbang Wang, Yunhua Hao
Pages: 3399-3403
Published online on: 25 January 2018

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Article Open Access

Protective effects of amifostine, curcumin and caffeic acid phenethyl ester against cisplatin-induced testis tissue damage in rats

Tolga Mercantepe, Deniz Unal, Levent Tümkaya, Zihni Acar Yazici
Pages: 3404-3412
Published online on: 31 January 2018

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Article

Triptolide induces autophagy and apoptosis through ERK activation in human breast cancer MCF‑7 cells

Huan Gao, Yue Zhang, Lei Dong, Xiao‑Yu Qu, Li‑Na Tao, Yue‑Ming Zhang, Jing‑Hui Zhai, Yan‑Qing Song
Pages: 3413-3419
Published online on: 01 February 2018

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Article Open Access

Assessment of telomerase activity in leukocytes of type 2 diabetes mellitus patients having or not foot ulcer: Possible correlation with other clinical parameters

Dimitrios Baltzis, Evangelia Meimeti, Maria G. Grammatikopoulou, Matthieu Roustit, Eleni Mavrogonatou, Dimitris Kletsas, Smaragda Efraimidou, Christos Manes, Taxiarchis K. Nikolouzakis, John Tsiaoussis, Aristides M. Tsatsakis, Demetrios A. Spandidos, Christina-Maria Trakatelli, Nikolaos Drakoulis
Pages: 3420-3424
Published online on: 25 January 2018

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Article Open Access

Glibenclamide exacerbates adriamycin-induced cardiotoxicity by activating oxidative stress-induced endoplasmic reticulum stress in rats

Meng‑Lin Liu, Meng‑Long Wang, Jing‑Jun Lv, Jie Wei, Jun Wan
Pages: 3425-3431
Published online on: 13 February 2018

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Article Open Access

Protective effect and molecular mechanism of liquiritin on oxybuprocaine-induced apoptosis of human corneal endothelial cells

Dan Li, Peng Zhang
Pages: 3432-3438
Published online on: 12 February 2018

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Article

GSK126 (EZH2 inhibitor) interferes with ultraviolet A radiation‑induced photoaging of human skin fibroblast cells

Haiyan Qin, Guang Zhang, Lianbo Zhang
Pages: 3439-3448
Published online on: 13 February 2018

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Article

TIPE2 is negatively correlated with tissue factor and thrombospondin-1 expression in patients with bronchial asthma

Guang Shi, Jun‑Wei Zhao, Xiao‑Xu Sun, Jun‑Fen Ma, Pan Wang, Fu‑Cheng He, Liang Ming
Pages: 3449-3454
Published online on: 14 February 2018

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Case Report

Diagnosis and management of spinal tuberculosis combined with brucellosis: A case report and literature review

Dexin Zou, Junlin Zhou, Xiaobing Jiang
Pages: 3455-3458
Published online on: 30 January 2018

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Article

The effects of phototherapy and melanocytes on keratinocytes

Luyan Tang, Wenyu Wu, Wenwen Fu, Yao Hu
Pages: 3459-3466
Published online on: 30 January 2018

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Article

Diagnostic value of OMOM capsule endoscopy for small bowel diseases in adults

Lili Zhang, Junsong Shen, Linchun Guo, Fenggan Cheng, Qi Fan, Keqian Ni, Shujing Xia, Detong Zhou
Pages: 3467-3470
Published online on: 13 February 2018

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Case Report

Kissing aneurysms of the distal anterior cerebral artery: A case report and literature review

Chuan‑Yi Fu, Jian‑Long Chen, Zhao‑Hui Liu, Peng‑Cheng Wang, Chuan‑Zhi Duan, Jian‑Nong Zhao
Pages: 3471-3476
Published online on: 09 February 2018

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Article

Slug inhibition increases radiosensitivity of nasopharyngeal carcinoma cell line C666‑1

Hongxia Yang, Gang Zhang, Xiaolin Che, Shudong Yu
Pages: 3477-3482
Published online on: 07 February 2018

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Article

High calcium diet alleviates 5/6 nephrectomy-induced bone deteriorations of lumbar vertebrae in mice

Hai‑Tao Hou, Ya‑Nan Wang, Shi‑Ze Shao, Song Fu, Xiang‑Peng Huang, Xiao‑Hui Wang
Pages: 3483-3488
Published online on: 14 February 2018

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Article

Semaphorin 3A promotes osteogenic differentiation in human alveolar bone marrow mesenchymal stem cells

Li Liu, Jue Wang, Xiaomeng Song, Qingping Zhu, Shuping Shen, Wei Zhang
Pages: 3489-3494
Published online on: 30 January 2018

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Article

GDF11/BMP11 as a novel tumor marker for liver cancer

Yong‑Hui Zhang, Lian‑Hong Pan, Yi Pang, Jin‑Xin Yang, Meng‑Jia Lv, Feng Liu, Xue‑Feng Qu, Xin‑Xin Chen, Hua‑Jun Gong, Dan Liu, Yong Wei
Pages: 3495-3500
Published online on: 12 February 2018

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Article

Enhanced percutaneous absorption of cilostazol nanocrystals using aqueous gel patch systems and clarification of the absorption mechanism

Chiaki Yoshioka, Yoshimasa Ito, Noriaki Nagai
Pages: 3501-3508
Published online on: 31 January 2018

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Article

JWA deficiency induces malignant transformation of murine embryonic fibroblast cells Erratum in /10.3892/etm.2018.6132

Hong Qi, Aiping Li
Pages: 3509-3515
Published online on: 03 January 2018

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Article

3-Methyladenine and dexmedetomidine reverse lipopolysaccharide-induced acute lung injury through the inhibition of inflammation and autophagy

Dengfeng Ding, Shiyuan Xu, Hongfei Zhang, Wei Zhao, Xueping Zhang, Yuanxu Jiang, Ping Wang, Zhongliang Dai, Junzhi Zhang
Pages: 3516-3522
Published online on: 02 February 2018

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Article

MicroRNA‑let‑7e regulates the progression and development of allergic rhinitis by targeting suppressor of cytokine signaling 4 and activating Janus kinase 1/signal transducer and activator of transcription 3 pathway

Lihua Li, Shaorong Zhang, Xunshuo Jiang, Yuehui Liu, Ke Liu, Chunping Yang
Pages: 3523-3529
Published online on: 01 February 2018

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Article

Berberine ameliorates neonatal necrotizing enterocolitis by activating the phosphoinositide 3-kinase/protein kinase B signaling pathway

Chengzhi Fang, Lili Xie, Chunmei Liu, Chunhua Fu, Wei Ye, Hong Liu, Binghong Zhang
Pages: 3530-3536
Published online on: 12 February 2018

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Article

Allicin activates autophagic cell death to alleviate the malignant development of thyroid cancer

Yangfeng Xiang, Jianqiang Zhao, Ming Zhao, Kejing Wang
Pages: 3537-3543
Published online on: 01 February 2018

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Article

Inhibitory effects of methamphetamine on mast cell activation and cytokine/chemokine production stimulated by lipopolysaccharide in C57BL/6J mice

Li Xue, Yan Geng, Ming Li, Yao‑Feng Jin, Hui‑Xun Ren, Xia Li, Feng Wu, Biao Wang, Wei‑Ying Cheng, Teng Chen, Yan‑Jiong Chen
Pages: 3544-3550
Published online on: 05 February 2018

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Article

Pterostilbene attenuates acute kidney injury in septic mice

Yizi Xia, Ying Chen, Luming Tang, Zheng Wang, Yu Zheng
Pages: 3551-3555
Published online on: 30 January 2018

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Article

Saccharum Alhagi polysaccharide-1 and -2 promote the immunocompetence of RAW264.7 macrophages in vitro

Gairu Li, Yang Xiang, Jin Zhao, Junmin Chang
Pages: 3556-3562
Published online on: 31 January 2018

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Article

Protective role of microRNA‑219‑5p inhibitor against spinal cord injury via liver receptor homolog‑1/Wnt/β‑catenin signaling pathway regulation

Jie Li, Liqiang Li, Yong Shen
Pages: 3563-3569
Published online on: 01 February 2018

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Article

Clinical and angiographic outcomes after combined direct and indirect bypass in adult patients with moyamoya disease: A retrospective study of 76 procedures

Jinbing Zhao, Hongyi Liu, Yuanjie  Zou, Wenbin Zhang, Shengxue He
Pages: 3570-3576
Published online on: 07 February 2018

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Article

Expression and secretion of neuregulin-1 in cardiac microvascular endothelial cells treated with angiogenic factors

Chengqiang Wu, Chun Gui, Lang Li, Yiheng Pang, Zhongli Tang, Jing Wei
Pages: 3577-3581
Published online on: 30 January 2018

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Article

Role of mitofusin 2 in the protective effect of breviscapine against hepatic ischemia/reperfusion injury in rats

Zhen Bao, Weijun Chen, Fan Pan, Bo Peng, Jin Gong
Pages: 3582-3588
Published online on: 05 February 2018

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Article

Risk factors for new-onset chronic kidney disease in patients who have received a liver transplant

Yuehong Li, Binbin Li, Wei Wang, Jiaxuan Lv
Pages: 3589-3595
Published online on: 31 January 2018

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Article

Immunological changes of T helper cells in flow cytometer‑sorted CD4+ T cells from patients with Hashimoto's thyroiditis

Yanying Guo, Jazyra Zynat Zynat, Shuqing Xing, Liang Xin, Suli Li, Nurongguli Mammat, Yuan Chen, Limin Zhao, Hongli Zhao, Xinling Wang
Pages: 3596-3602
Published online on: 01 February 2018

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Article

Overexpression of growth and differentiation factor-5 inhibits inflammatory factors released by intervertebral disc cells

Lin Shen, Yinghua Wu, Liang Han, Haiying Zhang
Pages: 3603-3608
Published online on: 14 February 2018

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Article

MicroRNA‑148b inhibits proliferation and the epithelial‑mesenchymal transition and increases radiosensitivity in non‑small cell lung carcinomas by regulating ROCK1

Haitao Luo, Caixia Liang
Pages: 3609-3616
Published online on: 07 February 2018

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Article

N‑methyl pyrrolidone promotes ankle fracture healing by inhibiting inflammation via suppression of the mitogen‑activated protein kinase signaling pathway

Jun Bian, Dan Cao, Jie Shen, Bo Jiang, Dan Chen, Lanzheng Bian
Pages: 3617-3622
Published online on: 07 February 2018

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Article

Age-dependent variations of cancellous bone in response to ovariectomy in C57BL/6J mice

Sheng Zhou, Guanghu Wang, Liang Qiao, Qiting Ge, Dongyang Chen, Zhihong Xu, Dongquan Shi, Jin Dai, Jinzhong Qin, Huajian Teng, Qing Jiang
Pages: 3623-3632
Published online on: 06 February 2018

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Article

The investigation of immunomodulatory activities of Gloeostereum incaratum polysaccharides in cyclophosphamide-induced immunosuppression mice

Di Wang, Qian Li, Yidi Qu, Mengya Wang, Lanzhou Li, Yang Liu, Yu Li
Pages: 3633-3638
Published online on: 30 January 2018

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Article

Local level of TGF-β1 determines the effectiveness of dexamethasone through regulating the balance of Treg/Th17 cells in TNBS-induced mouse colitis

Peng You, Ning Chen, Lin Su, Tao Peng, Guodong Chen, Yulan Liu
Pages: 3639-3649
Published online on: 08 February 2018

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Article

Curcumin inhibits the growth of liver cancer stem cells through the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway

Ji Wang, Chunying Wang, Gaofeng Bu
Pages: 3650-3658
Published online on: 29 January 2018

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Article

Influence of different concentrations of uric acid on oxidative stress in steatosis hepatocytes

Shi Cheng, Yan Yang, Yong Zhou, Wei Xiang, Hua Yao, Ling Ma
Pages: 3659-3665
Published online on: 12 February 2018

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Editorial Open Access

[Editorial] Spinal muscular atrophy, pediatric virology and gene therapy: A challenge of modern weakness and hope

Basil T. Darras, Ioannis N. Mammas, Demetrios A. Spandidos
Pages: 3671-3672
Published online on: 22 February 2018

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Spinal muscular atrophy type I and the dual role of viruses: An interview with Professor Basil T. Darras, Professor of Neurology (Pediatrics) at Harvard Medical School

Ioannis N. Mammas, Demetrios A. Spandidos
Pages: 3673-3679
Published online on: 22 February 2018

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Review Open Access

Dietary exosome-miR-23b may be a novel therapeutic measure for preventing Kashin-Beck disease (Review)

Yujie Ning, Xi Wang, Pan Zhang, Amin Liu, Xin Qi, Meidan Liu, Xiong Guo
Pages: 3680-3686
Published online on: 22 February 2018

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Article Open Access

Nasopharyngeal carcinoma: A review of current updates

Lei Wu, Churong Li, Li Pan
Pages: 3687-3692
Published online on: 20 February 2018

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Article Open Access

Influence of amygdalin on PDG, IGF and PDGFR expression in HSC-T6 cells

Huanhuan Luo, Fang Zhao, Fengxue Zhang, Ni Liu
Pages: 3693-3698
Published online on: 22 February 2018

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Article Open Access

Effect of YHHJ on the expression of the hepatocellular bile acid transporters multidrug resistance‑associated protein 2 and bile salt export pump in ethinylestradiol‑induced cholestasis

Jia Liu, Li‑Li Hou, Cui‑Ying Zhao
Pages: 3699-3704
Published online on: 26 February 2018

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Article Open Access

MicroRNA-34a regulates proliferation and apoptosis of gastric cancer cells by targeting silent information regulator 1

Xiaojing Deng, Hailun Zheng, Dapeng Li, Yongju Xue, Qizhi Wang, Shanjun Yan, Yu Zhu, Min Deng
Pages: 3705-3714
Published online on: 02 March 2018

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Article Open Access

Isolation, culture and induced differentiation of rabbit mesenchymal stem cells into osteoblasts

Hao Liu, Li‑Kun Wei, Xiao‑Fei Jian, Jie Huang, Hui Zou, Shi‑Zhan Zhang, Guang‑Hua Yuan
Pages: 3715-3724
Published online on: 26 February 2018

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Article Open Access

Decreased expression of sirtuin 3 protein correlates with early stage chronic renal allograft dysfunction in a rat kidney model

Qin Zhou, Daoyuan Lv, Yue Xia, Zhihong Zhao, Hequn Zou
Pages: 3725-3732
Published online on: 28 February 2018

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Article Open Access

Clinical significance of plasma globotriaosylsphingosine levels in Chinese patients with Fabry disease

Yan Ouyang, Bing Chen, Xiaoxia Pan, Zhaohui Wang, Hong Ren, Yaowen Xu, Liyan Ni, Xialian Yu, Li Yang, Nan Chen
Pages: 3733-3742
Published online on: 26 February 2018

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Article Open Access

MicroRNA-133b inhibits cell proliferation and promotes apoptosis by targeting cullin 4B in esophageal squamous cell carcinoma

Hairong Huang, Yang Xu, Zhong Guo, Xi Chen, Shaiguang Ji, Zhiyun Xu
Pages: 3743-3750
Published online on: 28 February 2018

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Article Open Access

Reverting doxorubicin resistance in colon cancer by targeting a key signaling protein, steroid receptor coactivator

Sang Xiong, Gong‑Wei Xiao
Pages: 3751-3758
Published online on: 28 February 2018

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Article Open Access

Curative effect of minimally invasive surgery on palmar and foot hyperhidrosis and its influence on serum-related cytokines and immunoglobulins

Wei Xi Li, Yong Kun Li, Hai Tao Lin
Pages: 3759-3764
Published online on: 15 February 2018

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Article Open Access

A probe into effect of Shoutai pill on endometrial receptivity

Lijun Zhao, Yang Xu, Xiaoling Duo, Xiaoying Tian, Peng Wang
Pages: 3765-3768
Published online on: 15 February 2018

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Article Open Access

Relationship between left ventricular diastolic dyssynchrony and systolic dyssynchrony in hypertrophic cardiomyopathy by single-cardiac real-time three-dimensional ultrasonography

Bing Xing, Ailin Cao, Wei Sun, Xiyan Hou
Pages: 3769-3774
Published online on: 15 February 2018

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Article Open Access

Propofol and sevoflurane combined with remifentanil on the pain index, inflammatory factors and postoperative cognitive function of spine fracture patients

Yu Zhao, Hongqi Zhang
Pages: 3775-3780
Published online on: 27 February 2018

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Article Open Access

miR-143-3p regulates cell proliferation and apoptosis by targeting IGF1R and IGFBP5 and regulating the Ras/p38 MAPK signaling pathway in rheumatoid arthritis

Zhenguo Yang, Jifu Wang, Zhuangzhuang Pan, Yihang Zhang
Pages: 3781-3790
Published online on: 28 February 2018

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Article Open Access

Chronic ethanol exposure induces SK-N-SH cell apoptosis by increasing N-methyl-D-aspartic acid receptor expression and intracellular calcium

Hongbo Wang, Xiaolong Wang, Yan Li, Hao Yu, Changliang Wang, Chunmei Feng, Guohui Xu, Jiajun Chen, Jiabin You, Pengfei Wang, Xu Wu, Rui Zhao, Guohua Zhang
Pages: 3791-3800
Published online on: 28 February 2018

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Article Open Access

Identification of functional modules induced by bare-metal stents and paclitaxel-eluting stents in coronary heart disease

Zhaobin Tang, Jingjing Gu, Ping Sun, Jing Zhao, Yonggang Zhao
Pages: 3801-3808
Published online on: 20 February 2018

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Article Open Access

Effect of probucol on hemodynamics, rheology and blood lipid of diabetic retinopathy

Hong Liu, Mingming Cai
Pages: 3809-3814
Published online on: 01 March 2018

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Article Open Access

Investigating the application of diving endoscopic technique in determining the extent of pituitary adenoma resection via the trans-nasal-sphenoidal approach

Hai‑Bin Gao, Li‑Qing Wang, Jian‑Yun Zhou, Wei Sun
Pages: 3815-3819
Published online on: 02 March 2018

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Article Open Access

Effects of low-level laser therapy following surgical extraction of the lower third molar with objective measurement of swelling using a three-dimensional system

Mahmut Koparal, Ayse Ozcan Kucuk, Hilal Alan, Fatih Asutay, Mehmet Avci
Pages: 3820-3826
Published online on: 02 March 2018

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Article Open Access

Extract of Rhus verniciflua stokes protects against renal ischemia-reperfusion injury by enhancing Nrf2-mediated induction of antioxidant enzymes

Du Ri Choi, Ji Heun Jeong, Kwang‑Sik Yu, Nam‑Seob Lee, Young‑Gil Jeong, Do Kyung Kim, Chun Soo Na, Dae Seung Na, Won Min Hwang, Seung‑Yun Han
Pages: 3827-3835
Published online on: 28 February 2018

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Article Open Access

Protective effects of paeonol on subacute/chronic brain injury during cerebral ischemia in rats

Bing Zhao, Qiao‑Juan Shi, Zhen‑Zhong Zhang, Shu‑Yan Wang, Xi Wang, Hao Wang
Pages: 3836-3846
Published online on: 26 February 2018

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Article Open Access

Aloperine activates the Nrf2‑ARE pathway when ameliorating early brain injury in a subarachnoid hemorrhage model Corrigendum in /10.3892/etm.2024.12552

Shibin Song, Yimin Chen, Feng Han, Minghao Dong, Xin Xiang, Jianmei Sui, Yuming Li, Hua Yang, Jian Liu
Pages: 3847-3855
Published online on: 26 February 2018

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Article Open Access

Methylene blue relieves the development of osteoarthritis by upregulating lncRNA MEG3 Retraction in /10.3892/etm.2024.12562

Xinyi Li, Chaoliang Tang, Jin Wang, Peipei Guo, Chengyao Wang, Yanlin Wang, Zongze Zhang, Huisheng Wu
Pages: 3856-3864
Published online on: 02 March 2018

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Article Open Access

Clinical implications of age and sex in the prevalence of periodontitis in Korean adults with diabetes

Kyungdo Han, Jun‑Beom Park
Pages: 3865-3873
Published online on: 20 February 2018

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Article Open Access

Tripterygium wilfordii mitigates hyperglycemia-induced upregulated Wnt/β-catenin expression and kidney injury in diabetic rats

Baochao Chang, Weidong Chen, Yan Zhang, Ping Yang, Lei Liu
Pages: 3874-3882
Published online on: 28 February 2018

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Article Open Access

Protective effect of Atriplex suberecta extract against oxidative and apoptotic hepatotoxicity

Mohammad K. Parvez, Ahmad H. Arbab, Mohammed S. Al‑Dosari, Adnan J. Al‑Rehaily, Perwez Alam, Khalid E. Ibrahim, Mansour S. Alsaid, Syed Rafatullah
Pages: 3883-3891
Published online on: 02 March 2018

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Article Open Access

Correlation between the expression of Drp1 in vascular endothelial cells and inflammatory factors in hypertension rats

Xinghui Liu, Hongwen Tan, Xiaoqiao Liu, Qiang Wu
Pages: 3892-3898
Published online on: 27 February 2018

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Article Open Access

Accurate and continuous ultrasonography evaluation of small diameter vascular prostheses in vivo

Jing Shi, Jialing Zhang, Meng Yin, Qian Wang, Jun Du
Pages: 3899-3907
Published online on: 26 February 2018

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Article Open Access

Advanced oxidation protein products inhibit the autophagy of renal tubular epithelial cells

Jun Zhang, Xiaohong Xiang, Shuangshuang Shu, Cuiling Zhang, Yuling Liang, Tingting Jiang, Wenying Zhang, Tingting Guo, Xiujie Liang, Xun Tang
Pages: 3908-3916
Published online on: 15 February 2018

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Article Open Access

Anti-proliferative effect of isorhamnetin on HeLa cells through inducing G2/M cell cycle arrest

Juan Wei, Hailan Su, Yang Bi, Jixin Li, Lidan Feng, Wenjun Sheng
Pages: 3917-3923
Published online on: 26 February 2018

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Article Open Access

Correlation between serum inflammatory factors TNF-α, IL-8, IL-10 and Henoch-Schonlein purpura with renal function impairment

Liangdong Yuan, Quanyi Wang, Shiqi Zhang, Ling Zhang
Pages: 3924-3928
Published online on: 16 February 2018

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Article Open Access

Rat vibrissa dermal papilla cells promote healing of spinal cord injury following transplantation

Meiying Li, Xianglin Mei, Shuang Lv, Zechuan Zhang, Jinying Xu, Dongjie Sun, Jiayi Xu, Xia He, Guangfan Chi, Yulin Li
Pages: 3929-3939
Published online on: 28 February 2018

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Article Open Access

Evaluation of related factors, prediction and treatment drugs of no-reflow phenomenon in patients with acute ST-segment elevation myocardial infarction after direct PCI

Hui Li, Du-Guan Fu, Fu-Yuan Liu, Heng Zhou, Xiao-Mei Li
Pages: 3940-3946
Published online on: 27 February 2018

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Article Open Access

Effect of revascularization on IL-6 and TNF-α in patients with thromboangiitis obliterans

Shifeng Wu, Xin Sun, Wei Wu, Dazhi Shi, Tao Jiang
Pages: 3947-3951
Published online on: 20 February 2018

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Article Open Access

Genetic polymorphism in the asporin gene is not a key risk factor for osteoarthritis: Evidence based on an updated cumulative meta-analysis

Jing Wang, Aimin Yang, Jie Zhang, Na Sun, Xiangwen Li, Xinghui Li, Qiling Liu, Jun Li, Xiaomei Ren, Zunhua Ke, Rongqiang Zhang
Pages: 3952-3966
Published online on: 26 February 2018

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Article Open Access

Insulin alleviates mitochondrial oxidative stress involving upregulation of superoxide dismutase 2 and uncoupling protein 2 in septic acute kidney injury

Guang‑Dao Chen, Jun‑Liang Zhang, Yi‑Ting Chen, Ju‑Xing Zhang, Tao Wang, Qi‑Yi Zeng
Pages: 3967-3975
Published online on: 26 February 2018

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Case Report

Molecular targeted therapies of renal cell carcinoma considering life stage of the patient: Two case reports

Hisashi Takeuchi, Naoto Tokuyama, Isao Kuroda, Teiichiro Aoyagi
Pages: 3976-3980
Published online on: 20 February 2018

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Article

Utility of dermoscopy for evaluating the therapeutic efficacy of tacrolimus ointment plus 308-nm excimer laser combination therapy in localized vitiligo patients

Lu‑Mei Wang, Wan‑Jiao Lu, Jing‑Tao Yuan, Bi‑Bing Zeng, Dan Li, Feng Zhang, Jun‑Jie Li
Pages: 3981-3988
Published online on: 28 February 2018

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Article

Gene expression analysis for pneumonia caused by Gram-positive bacterial infection

Rufu Jia, Jingyan Yang, Ying Cui, Dongjie Guo, Tiejun Li
Pages: 3989-3996
Published online on: 28 February 2018

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Case Report

Osteoporosis as an initial manifestation in a patient with Crohn's disease: A case report

Hongyun Wei, Chunhui Ouyang, Dehong Peng, Fanggen Lu, Jie Zhang
Pages: 3997-4000
Published online on: 28 February 2018

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Case Report

Multiple pelvic accessory spleen: Rare case report with review of literature

Yourong Feng, Yanyan Shi, Bo Wang, Jing Li, Ding Ma, Shixuan Wang, Mingfu Wu
Pages: 4001-4004
Published online on: 28 February 2018

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Article

Tongluo Xingnao effervescent tablet reverses memory deficit and reduces plaque load in APPswe/PS1dE9 mice

Wenjun Fu, Yuan Dai, Tao Ma, Jiangping Wei, Huan Chen, Shijun Xu
Pages: 4005-4013
Published online on: 26 February 2018

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Article

β-Endorphin attenuates collagen-induced arthritis partially by inhibiting peripheral pro-inflammatory mediators

Xiaofen He, Lei Huang, Shenchen Qiu, Xiaohu Yin, Yafang Shen, Yuanyuan Wu, Yongliang Jiang, Jianqiao Fang
Pages: 4014-4018
Published online on: 28 February 2018

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Article

Tumor suppressor miR-211-5p is associated with cellular migration, proliferation and apoptosis in renal cell carcinoma

Jing Quan, Xiang Pan, Tao He, Canbin Lin, Yulin Lai, Peijie Chen, Zeng Zhang, Shangqi Yang, Tao Wang, Yongqing Lai
Pages: 4019-4028
Published online on: 28 February 2018

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Article

Leukocyte depletion does not affect the in vitro healing ability of platelet rich plasma

Ilaria Giusti, Marianna Di Francesco, Sandra D'Ascenzo, Paola Palumbo, Anna Rughetti, Luigi Dell'Orso, Paola Annunziata Varasano, Gabriella Lucidi Pressanti, Vincenza Dolo
Pages: 4029-4038
Published online on: 22 February 2018

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Article

miR-216a-5p acts as an oncogene in renal cell carcinoma Corrigendum in /10.3892/etm.2024.12443

Peijie Chen, Jing Quan, Lu Jin, Canbin Lin, Weijie Xu, Jinling Xu, Xin Guan, Zebo Chen, Liangchao Ni, Shangqi Yang, Yun Chen, Yongqing Lai
Pages: 4039-4046
Published online on: 20 February 2018

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Article

Enhanced antitumor activity of combined megestrol acetate and arsenic trioxide treatment in liver cancer cells

Yan Xia, Xianhao Liu, Beibei Liu, Xiaoshi Zhang, Geng Tian
Pages: 4047-4055
Published online on: 28 February 2018

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Article

Knockdown of dickkopf2 inhibits vascular endothelia growth factor expression through the Wnt/β-catenin signaling pathway in human retinal pigment epithelial cells under hypoxic conditions

Yu Zhao, Bin Wu, Ye Liu, Jun Xu, Qichang Yan, Jinsong Zhang
Pages: 4056-4060
Published online on: 28 February 2018

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March-2026 Volume 31 Issue 3

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Article Open Access

Effect of SGLT2 inhibitors on heart failure outcomes in patients with and without diabetes: A systematic review and meta‑analysis of randomized controlled trials

Duaa Abdullah Bafail, Noura Hamdi Alhalees
Article Number: 84
Published online on: 28 January 2026

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Article Open Access

Exploring the protective mechanisms and therapeutic potential of carnosic acid against acute respiratory distress syndrome through molecular docking, molecular dynamics and experimental verification

Quan Li, Lili Ding, Haijun Sun, Weichao Ding, Mengmeng Wang, Zhaorui Sun, Congxue Ma
Article Number: 83
Published online on: 28 January 2026

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Review

Exploring the roots of schizophrenia: Current research and future directions (Review)

Shuang Lv, Chunxia Luo
Article Number: 82
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] miR‑146a‑5p protects against renal injury in MRL/lpr mice via improvement of the Treg/Th17 imbalance by targeting the TRAF6/NF‑κB axis

Jiajia Teng, Feng Yang, Xiaoling Li
Article Number: 81
Published online on: 28 January 2026

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[Retracted] MicroRNA‑24‑3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl‑2‑like protein 11

Huanxin Zhang, Shizhen Xue, Yi Feng, Jun Shen, Jixian Zhao
Article Number: 80
Published online on: 26 January 2026

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Efficacy and safety of unilateral biportal endoscopy vs. percutaneous endoscopic interlaminar approach in lumbar disc herniation: A meta‑analysis​

Yuhao Gao, Fangzheng He, Ji Wen, Shilei Qin, Pengfei Han, Yunfeng Xu
Article Number: 79
Published online on: 23 January 2026

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Case Report Open Access

Intralobar pulmonary sequestration coexisting with pulmonary cryptococcosis: A case report and literature review

Dan Cheng, Yue Wang, Jun Li, Dan Yu, Yunyun Wang, Jinbo Fan, Jiankun Wang, Liqun He
Article Number: 78
Published online on: 23 January 2026

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Tumor‑associated macrophages suppress estrogen receptor‑β expression in triple‑negative breast cancer through the PI3K/AKT pathway

Qiulei Zhang, Di Guo, Gaoran Xu, Rong Xie, Yuqing Deng, Peng Fu, Jinnan Wan
Article Number: 77
Published online on: 21 January 2026

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Development of a diagnostic model for esophageal achalasia assessed by esophageal high‑resolution manometry using artificial intelligence

Maiko Tabuchi, Yasuhiko Nakao, Hitomi Minami, Hiroko Inomata, Junya Shiota, Taro Akashi, Keiichi Hashiguchi, Moto Kitayama, Kayoko Matsushima, Naoyuki Yamaguchi, Yuko Akazawa, Hisamitsu Miyaaki
Article Number: 76
Published online on: 21 January 2026

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Case Report

Use of metagenomic next‑generation sequencing to diagnose Tropheryma whipplei infection‑related pneumonia: A case report

Yutu Luo, Haibing Ding, Jiahua Pan, Guangyang Xu
Article Number: 75
Published online on: 21 January 2026

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Effect of rivaroxaban on DNA damage in an ischemia-reperfusion model: Evaluation of 8‑OHdG levels

Ceren Sayarer, Abidin Cenk Erdal, Tuğra Gençpinar, Özlem Gürsoy Doruk, Tuncay Küme
Article Number: 74
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Hepatoprotective activity of chrysin is mediated through TNF‑α in chemically‑induced acute liver damage: An in vivo study and molecular modeling 

Anca Hermenean, Teodora Mariasiu, Inmaculada Navarro‑González, Josefina Vegara‑Meseguer, Eftimie Miuțescu, Sandipan Chakraborty, Horacio Pérez-Sánchez
Article Number: 73
Published online on: 21 January 2026

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Retraction Open Access

[Retracted] Gambogic acid suppresses colon cancer cell activity in vitro

Zailong Zhou, Jian Ma
Article Number: 72
Published online on: 19 January 2026

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Case Report

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review

Burak Menekse, Enes Ucgul, Abdullatif Bakir, Sema Hepsen, Ilknur Ozturk Unsal, Muhammed Kizilgul, Takako Araki, Erman Cakal
Article Number: 71
Published online on: 16 January 2026

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Postoperative hypofractionated proton beam therapy to control recurrent paraganglioma at the jugular foramen: A case report

Wei Wang, Yingxia Yuan, Jiwei Bai, Yue Zou, Dongxue Zhou, Jun Zhao, Shuyan Zhang, Zishen Wang, Jie Wang, Jingjing Kong, Lu Yang, Masashi Mizumoto, Hideyuki Sakurai, Shosei Shimizu
Article Number: 70
Published online on: 16 January 2026

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Article

Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury

Ruoran Wang, Min He, Jianguo Xu
Article Number: 69
Published online on: 16 January 2026

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Retraction Open Access

[Retracted] β‑asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal‑regulated kinase signaling pathway

Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong Li
Article Number: 68
Published online on: 12 January 2026

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Case Report Open Access

Rare co‑occurrence of gastrointestinal stromal tumors and leiomyomas: A case report and review of the literature

Yu Zhang, Xiaoqiong Shi, Wenfu Xie, Meilin He, Shan Zhang, Xue Peng, Hao Lei, Xulei Li, Haiying Liu, Qiao Shu, Fangyuan Zou, Mingyong Wei
Article Number: 67
Published online on: 09 January 2026

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Article Open Access

No increased risk of hepatic enzyme abnormalities with non‑peptidic thrombopoietin receptor agonists in immune thrombocytopenia: A meta‑analysis of randomized controlled trials

Nan Shen, Rang Wu, Tiantian Lu, Song Liu, Yazhou Jiang, Jingjing Yan, Tao Ning, Chang Dong, Jianqin Li, Suyue Zhu
Article Number: 66
Published online on: 09 January 2026

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Case Report

Submucosal colonic fecalith mimicking a submucosal malignant tumor at the anastomotic site after colon cancer: A case report

Motoaki Yuhi, Masatsugu Hiraki, Shin Takesue, Mariko Hashiguchi, Megumi Nishiyama, Yoshiaki Egashira, Tatsuya Manabe, Hirokazu Noshiro
Article Number: 65
Published online on: 08 January 2026

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Article

Clinical characteristics of acute primary angle closure following COVID‑19 during the Omicron outbreak in China

Jianhui Zhang, Yingying Xue, Liu Zhang, Yuhong Wang, Shancheng Si
Article Number: 64
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Aberrant expression and mechanism of miR‑130b‑3p/phosphatase and tensin homolog in nephroblastoma in children

Yifeng Hu, Jingtie Yan
Article Number: 63
Published online on: 05 January 2026

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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April-2026 Volume 31 Issue 4

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