Osteoporosis as an initial manifestation in a patient with Crohn's disease: A case report

  • Authors:
    • Hongyun Wei
    • Chunhui Ouyang
    • Dehong Peng
    • Fanggen Lu
    • Jie Zhang
  • View Affiliations

  • Published online on: February 28, 2018     https://doi.org/10.3892/etm.2018.5910
  • Pages: 3997-4000
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Abstract

The present case report details a rare case of osteoporosis as the initial manifestation of Crohn's disease (CD). A 43-year-old male was referred to the Second Xiangya Hospital of Central South University (Changsha, China) for further examination of low back pain (LBP) without digestive symptoms. Bone mineral density (BMD) analysis indicated osteoporosis, particularly in the lumbar spine. Endoscopy revealed an inflamed and strictured ileocecal valve with less inflammation in the ascending, transverse colon, sigmoid colon and rectum, compatible with CD, which was in accordance with the appearance of an abdominal computed tomography scan. Duodenal‑balloon enteroscopy indicated segmental ulceration and stricture in the jejunum, in accordance with CD. The patient was diagnosed with CD following examination. It was suspected that osteoporosis may be an extra‑intestinal manifestation of CD. Steroids and biological agents were prescribed in sequence. LBP and BMD rapidly improved following treatment, and inflammatory markers returned to normal after 1.5 years of treatment. According to this case, osteoporosis with unknown causes should be considered as a possible sign of small intestinal CD.
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April-2018
Volume 15 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Wei H, Ouyang C, Peng D, Lu F and Zhang J: Osteoporosis as an initial manifestation in a patient with Crohn's disease: A case report. Exp Ther Med 15: 3997-4000, 2018
APA
Wei, H., Ouyang, C., Peng, D., Lu, F., & Zhang, J. (2018). Osteoporosis as an initial manifestation in a patient with Crohn's disease: A case report. Experimental and Therapeutic Medicine, 15, 3997-4000. https://doi.org/10.3892/etm.2018.5910
MLA
Wei, H., Ouyang, C., Peng, D., Lu, F., Zhang, J."Osteoporosis as an initial manifestation in a patient with Crohn's disease: A case report". Experimental and Therapeutic Medicine 15.4 (2018): 3997-4000.
Chicago
Wei, H., Ouyang, C., Peng, D., Lu, F., Zhang, J."Osteoporosis as an initial manifestation in a patient with Crohn's disease: A case report". Experimental and Therapeutic Medicine 15, no. 4 (2018): 3997-4000. https://doi.org/10.3892/etm.2018.5910