Osteoporosis as an initial manifestation in a patient with Crohn's disease: A case report

Wei,Hongyun; Ouyang,Chunhui; Peng,Dehong; Lu,Fanggen; Zhang,Jie

doi:10.3892/etm.2018.5910

April-2018 Volume 15 Issue 4

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April-2018 Volume 15 Issue 4

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Case Report

Osteoporosis as an initial manifestation in a patient with Crohn's disease: A case report

Authors:
- Hongyun Wei
- Chunhui Ouyang
- Dehong Peng
- Fanggen Lu
- Jie Zhang
View Affiliations / Copyright

Affiliations: Department of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China, Department of Radiology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China
Pages: 3997-4000
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Published online on: February 28, 2018

https://doi.org/10.3892/etm.2018.5910
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Abstract

The present case report details a rare case of osteoporosis as the initial manifestation of Crohn's disease (CD). A 43-year-old male was referred to the Second Xiangya Hospital of Central South University (Changsha, China) for further examination of low back pain (LBP) without digestive symptoms. Bone mineral density (BMD) analysis indicated osteoporosis, particularly in the lumbar spine. Endoscopy revealed an inflamed and strictured ileocecal valve with less inflammation in the ascending, transverse colon, sigmoid colon and rectum, compatible with CD, which was in accordance with the appearance of an abdominal computed tomography scan. Duodenal‑balloon enteroscopy indicated segmental ulceration and stricture in the jejunum, in accordance with CD. The patient was diagnosed with CD following examination. It was suspected that osteoporosis may be an extra‑intestinal manifestation of CD. Steroids and biological agents were prescribed in sequence. LBP and BMD rapidly improved following treatment, and inflammatory markers returned to normal after 1.5 years of treatment. According to this case, osteoporosis with unknown causes should be considered as a possible sign of small intestinal CD.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Osteoporosis as an initial manifestation in a patient with Crohn's disease: A case report

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Abstract

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