Open Access

Pressure ulcer healing promoted by adequate protein intake in rats

  • Authors:
    • Zhanfen Qin
    • Yao Wang
    • Wei Zhao
    • Yanan Zhang
    • Yiqing Tian
    • Sujuan Sun
    • Xian Li
  • View Affiliations

  • Published online on: March 8, 2018     https://doi.org/10.3892/etm.2018.5934
  • Pages: 4173-4178
  • Copyright: © Qin et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The effect of protein intake on rat pressure ulcer healing was evaluated. One hundred rats were numbered according to body weight and then they were randomly divided into 4 groups (n=25) using the random number table. After rat models of stage II pressure ulcer were established, they were fed with feed containing different protein levels (10, 15, 20 and 25%). Healing time, pressure ulcer area, body weight, albumin (ALB) and hemoglobin (Hb) levels among groups were compared. Hematoxylin and eosin (H&E) staining was also performed to observe pressure ulcer tissue structure. In the healing process of pressure ulcer, rats with 20% protein intake had the shortest healing time and the smallest pressure ulcer area. Body weight, ALB and Hb levels were much closer to the normal level. H&E staining result also suggested that the pressure ulcer healing degree of rats with 20% protein intake was much better than the others. Adequate protein intake is therefore conducive to pressure ulcer healing, while excessive or insufficient protein intake has negative impact on healing.
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May-2018
Volume 15 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Qin Z, Wang Y, Zhao W, Zhang Y, Tian Y, Sun S and Li X: Pressure ulcer healing promoted by adequate protein intake in rats. Exp Ther Med 15: 4173-4178, 2018
APA
Qin, Z., Wang, Y., Zhao, W., Zhang, Y., Tian, Y., Sun, S., & Li, X. (2018). Pressure ulcer healing promoted by adequate protein intake in rats. Experimental and Therapeutic Medicine, 15, 4173-4178. https://doi.org/10.3892/etm.2018.5934
MLA
Qin, Z., Wang, Y., Zhao, W., Zhang, Y., Tian, Y., Sun, S., Li, X."Pressure ulcer healing promoted by adequate protein intake in rats". Experimental and Therapeutic Medicine 15.5 (2018): 4173-4178.
Chicago
Qin, Z., Wang, Y., Zhao, W., Zhang, Y., Tian, Y., Sun, S., Li, X."Pressure ulcer healing promoted by adequate protein intake in rats". Experimental and Therapeutic Medicine 15, no. 5 (2018): 4173-4178. https://doi.org/10.3892/etm.2018.5934