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Article

Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis

  • Authors:
    • Jiakai Li
    • Chuangui Li
    • Jiaojiao Li
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, The Hainan Branch of The Chinese PLA General Hospital, Sanya, Hainan 572013, P.R. China, Department of Radiology, The First Affiliated Hospital, Northern Hebei College, Zhangjiakou, Hebei 075000, P.R. China, Department of Radiology, The General Hospital, Tianjin Medical University, Tianjin, Hebei 300052, P.R. China
  • Pages: 413-419
    |
    Published online on: May 11, 2018
       https://doi.org/10.3892/etm.2018.6154
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Abstract

The aim of the present study was to investigate the computed tomography (CT) manifestations of Wegener granulomatosis (WG) in the chest and potential reasons for misdiagnosis. Conventional CT scans and clinical data of 45 patients with WG were retrospectively analyzed. Patients typically presented with multiple system involvement, primarily in the upper and lower respiratory tract. The incidence of thoracic involvement was 75.56% (34/45). Radiographic features were varied between cases in the present study, with the most common features being numerous cavitary nodules and masses in the lungs. Cavitations were usually irregular, with uneven wall thickness, partial centrality, fuzzy inner edges and piecemeal necrosis. These results indicate that WG typically has multiple system involvement, with the chest being most prominent. Multiple variable‑sized cavitary nodules with irregular edges and piecemeal necrosis were the most notable features revealed using CT scanning; however, in order to give a definitive diagnosis, biopsies should be performed.
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Copy and paste a formatted citation
Spandidos Publications style
Li J, Li C and Li J: Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis. Exp Ther Med 16: 413-419, 2018.
APA
Li, J., Li, C., & Li, J. (2018). Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis. Experimental and Therapeutic Medicine, 16, 413-419. https://doi.org/10.3892/etm.2018.6154
MLA
Li, J., Li, C., Li, J."Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis". Experimental and Therapeutic Medicine 16.1 (2018): 413-419.
Chicago
Li, J., Li, C., Li, J."Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis". Experimental and Therapeutic Medicine 16, no. 1 (2018): 413-419. https://doi.org/10.3892/etm.2018.6154
Copy and paste a formatted citation
x
Spandidos Publications style
Li J, Li C and Li J: Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis. Exp Ther Med 16: 413-419, 2018.
APA
Li, J., Li, C., & Li, J. (2018). Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis. Experimental and Therapeutic Medicine, 16, 413-419. https://doi.org/10.3892/etm.2018.6154
MLA
Li, J., Li, C., Li, J."Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis". Experimental and Therapeutic Medicine 16.1 (2018): 413-419.
Chicago
Li, J., Li, C., Li, J."Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis". Experimental and Therapeutic Medicine 16, no. 1 (2018): 413-419. https://doi.org/10.3892/etm.2018.6154
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