|
1
|
Snape WJ Jr, Williams R and Hyman PE:
Defect in colonic smooth muscle contraction in patients with
ulcerative colitis. Am J Physiol. 261:G987–G991. 1991.PubMed/NCBI
|
|
2
|
Severi C, Sferra R, Scirocco A, Vetuschi
A, Pallotta N, Pronio A, Caronna R, Di Rocco G, Gaudio E,
Corazziari E and Onori P: Contribution of intestinal smooth muscle
to Crohn's disease fibrogenesis. Eur J Histochem. 58:24572014.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Vermillion DL, Huizinga JD, Riddell RH and
Collins SM: Altered small intestinal smooth muscle function in
Crohn's disease. Gastroenterology. 104:1692–1699. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Vrees MD, Pricolo VE, Potenti FM and Cao
W: Abnormal motility in patients with ulcerative colitis: The role
of inflammatory cytokines. Arch Surg. 137:439–446. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Shea-Donohue T, Notari L, Sun R and Zhao
A: Mechanisms of smooth muscle responses to inflammation.
Neurogastroenterol Motil. 24:802–811. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Shi XZ and Sarna SK: Transcriptional
regulation of inflammatory mediators secreted by human colonic
circular smooth muscle cells. Am J Physiol Gastrointest Liver
Physiol. 289:G274–G284. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Salinthone S, Singer CA and Gerthoffer WT:
Inflammatory gene expression by human colonic smooth muscle cells.
Am J Physiol Gastrointest Liver Physiol. 287:G627–G637. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Abraham C and Cho JH: Inflammatory bowel
disease. N Engl J Med. 361:2066–2078. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Bähler C, Schoepfer AM, Vavricka SR,
Brüngger B and Reich O: Chronic comorbidities associated with
inflammatory bowel disease: Prevalence and impact on healthcare
costs in Switzerland. Eur J Gastroenterol Hepatol. 29:916–925.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Tamez-Pérez HE, Quintanilla-Flores DL,
Rodríguez-Gutiérrez R, González-González JG and Tamez-Peña AL:
Steroid hyperglycemia: Prevalence, early detection and therapeutic
recommendations: A narrative review. World J Diabetes. 6:1073–1081.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Fakhoury M, Negrulj R, Mooranian A and
Al-Salami H: Inflammatory bowel disease: Clinical aspects and
treatments. J Inflamm Res. 7:113–120. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Pernicova I and Korbonits M:
Metformin-mode of action and clinical implications for diabetes and
cancer. Nat Rev Endocrinol. 10:143–156. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Cameron AR, Morrison VL, Levin D, Mohan M,
Forteath C, Beall C, McNeilly AD, Balfour DJ, Savinko T, Wong AK,
et al: Anti-inflammatory effects of metformin irrespective of
diabetes status. Circ Res. 119:652–665. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Hirsch HA, Iliopoulos D and Struhl K:
Metformin inhibits the inflammatory response associated with
cellular transformation and cancer stem cell growth. Proc Natl Acad
Sci USA. 110:972–977. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Kim SA and Choi HC: Metformin inhibits
inflammatory response via AMPK-PTEN pathway in vascular smooth
muscle cells. Biochem Biophys Res Commun. 425:866–872. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kita Y, Takamura T, Misu H, Ota T, Kurita
S, Takeshita Y, Uno M, Matsuzawa-Nagata N, Kato K, Ando H, et al:
Metformin prevents and reverses inflammation in a non-diabetic
mouse model of nonalcoholic steatohepatitis. PLoS One.
7:e430562012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Cao X, Li H, Tao H, Wu N, Yu L, Zhang D,
Lu X, Zhu J, Lu Z and Zhu Q: Metformin inhibits vascular
calcification in female rat aortic smooth muscle cells via the
AMPK-eNOS-NO pathway. Endocrinology. 154:3680–3689. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Lee SY, Lee SH, Yang EJ, Kim EK, Kim JK,
Shin DY and Cho ML: Metformin ameliorates inflammatory bowel
disease by suppression of the STAT3 signaling pathway and
regulation of the between Th17/Treg balance. PLoS One.
10:e01358582015. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Isoda K, Young JL, Zirlik A, MacFarlane
LA, Tsuboi N, Gerdes N, Schönbeck U and Libby P: Metformin inhibits
proinflammatory responses and nuclear factor-kappaB in human
vascular wall cells. Arterioscler Thromb Vasc Biol. 26:611–617.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Al-Dwairi A, Alqudah TE, Al-Shboul O,
Alqudah M, Mustafa AG and Alfaqih MA: Glucagon-like peptide-1
exerts anti-inflammatory effects on mouse colon smooth muscle cells
through the cyclic adenosine monophosphate/nuclear factor-κB
pathway in vitro. J Inflamm Res. 11:95–109. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Berkes J, Viswanathan VK, Savkovic SD and
Hecht G: Intestinal epithelial responses to enteric pathogens:
Effects on the tight junction barrier, ion transport, and
inflammation. Gut. 52:439–451. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Brynskov J, Foegh P, Pedersen G, Ellervik
C, Kirkegaard T, Bingham A and Saermark T: Tumour necrosis factor
alpha converting enzyme (TACE) activity in the colonic mucosa of
patients with inflammatory bowel disease. Gut. 51:37–43. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Neurath MF: Cytokines in inflammatory
bowel disease. Nat Rev Immunol. 14:329–342. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Rizzo G, Pugliese D, Armuzzi A and Coco C:
Anti-TNF alpha in the treatment of ulcerative colitis: A valid
approach for organ-sparing or an expensive option to delay surgery?
World J Gastroenterol. 20:4839–4845. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Lv R, Qiao W, Wu Z, Wang Y, Dai S, Liu Q
and Zheng X: Tumor necrosis factor alpha blocking agents as
treatment for ulcerative colitis intolerant or refractory to
conventional medical therapy: A meta-analysis. PLoS One.
9:e866922014. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Scarpa M, Kessler S, Sadler T, West G,
Homer C, McDonald C, de la Motte C, Fiocchi C and Stylianou E: The
epithelial danger signal IL-1α is a potent activator of fibroblasts
and reactivator of intestinal inflammation. Am J Pathol.
185:1624–1637. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Papadakis KA and Targan SR: Role of
cytokines in the pathogenesis of inflammatory bowel disease. Annu
Rev Med. 51:289–298. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Dionne S, D'Agata DD, Hiscott J, Vanounou
T and Seidman EG: Colonic explant production of IL-1 and its
receptor antagonist is imbalanced in inflammatory bowel disease
(IBD). Clin Exp Immunol. 112:435–442. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Cominelli F and Pizarro TT: Interleukin-1
and interleukin-1 receptor antagonist in inflammatory bowel
disease. Aliment Pharmacol Ther. 10:49–53. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Ghia JE, Galeazzi F, Ford DC, Hogaboam CM,
Vallance BA and Collins S: Role of M-CSF-dependent macrophages in
colitis is driven by the nature of the inflammatory stimulus. Am J
Physiol Gastrointest Liver Physiol. 294:G770–G777. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Marshall D, Cameron J, Lightwood D and
Lawson AD: Blockade of colony stimulating factor-1 (CSF-I) leads to
inhibition of DSS-induced colitis. Inflamm Bowel Dis. 13:219–224.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Franzè E, Marafini I, de Simone V,
Monteleone I, Caprioli F, Colantoni A, Ortenzi A, Crescenzi F, Izzo
R, Sica G, et al: Interleukin-34 induces Cc-chemokine ligand 20 in
gut epithelial cells. J Crohns Colitis. 10:87–94. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Werner L, Guzner-Gur H and Dotan I:
Involvement of CXCR4/CXCR7/CXCL12 interactions in inflammatory
bowel disease. Theranostics. 3:40–46. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Danese S and Gasbarrini A: Chemokines in
inflammatory bowel disease. J Clin Pathol. 58:1025–1027. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Mazzucchelli L, Hauser C, Zgraggen K,
Zgraggen K, Wagner HE, Hess MW, Laissue JA and Mueller C:
Differential in situ expression of the genes encoding the
chemokines MCP-1 and RANTES in human inflammatory bowel disease. J
Pathol. 178:201–206. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Luo Y and Dorf ME: Beta-chemokine TCA3
binds to mesangial cells and induces adhesion, chemotaxis, and
proliferation. J Immunol. 156:742–748. 1996.PubMed/NCBI
|
|
37
|
Scheerens H, Hessel E, de Waal-Malefyt R,
Leach MW and Rennick D: Characterization of chemokines and
chemokine receptors in two murine models of inflammatory bowel
disease: IL-10-/-mice and Rag-2-/-mice reconstituted with CD4+
CD45RBhigh T cells. Eur J Immunol. 31:1465–1474. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Xia XM, Wang FY, Zhou J, Hu KF, Li SW and
Zou BB: CXCR4 antagonist AMD3100 modulates claudin expression and
intestinal barrier function in experimental colitis. PLoS One.
6:e272822011. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Koh SJ, Kim JM, Kim IK, Ko SH and Kim JS:
Anti-inflammatory mechanism of metformin and its effects in
intestinal inflammation and colitis-associated colon cancer. J
Gastroenterol Hepatol. 29:502–510. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Kothari V, Galdo JA and Mathews ST:
Hypoglycemic agents and potential anti-inflammatory activity. J
Inflamm Res. 9:27–38. 2016.PubMed/NCBI
|
|
41
|
Salminen A, Hyttinen JM and Kaarniranta K:
AMP-activated protein kinase inhibits NF-κB signaling and
inflammation: Impact on healthspan and lifespan. J Mol Med (Berl).
89:667–676. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
He C, Li H, Viollet B, Zou MH and Xie Z:
AMPK suppresses vascular inflammation in vivo by inhibiting signal
transducer and activator of transcription-1. Diabetes.
64:4285–4297. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Atreya I, Atreya R and Neurath MF:
NF-kappaB in inflammatory bowel disease. J Intern Med. 263:591–596.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Nair DG, Miller KG, Lourenssen SR and
Blennerhassett MG: Inflammatory cytokines promote growth of
intestinal smooth muscle cells by induced expression of PDGF-Rβ. J
Cell Mol Med. 18:444–454. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Guan Q and Zhang J: Recent advances: The
imbalance of cytokines in the pathogenesis of inflammatory bowel
disease. Mediators Inflamm. 2017:48102582017. View Article : Google Scholar : PubMed/NCBI
|
