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Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome

  • Authors:
    • Hang Chen
    • Jun Zhang
    • Fang Qin
    • Xinyun Chen
    • Xiaojing Jiang
  • View Affiliations / Copyright

    Affiliations: Department of Cardiology, The First People's Hospital of Chengdu, Chengdu, Sichuan 610000, P.R. China
  • Pages: 619-622
    |
    Published online on: May 31, 2018
       https://doi.org/10.3892/etm.2018.6246
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Abstract

Relationship between serum high sensitive C-reactive protein (hs-CRP) and pregnancy-induced hypertension syndrome (PIH) was investigated. One hundred and twenty patients with PIH treated in the First People's Hospital of Chengdu (60 cases of mild preeclampsia, 60 cases of severe preeclampsia) were enrolled in the study. The control group included 60 women with normal singleton pregnancy. Serum hs-CRP and microalbuminuria (mALB) levels were measured by an AU5800 automatic biochemical analyzer (Beckerman Coulter), and the risk factors were analyzed by ROC curve analysis. Patients with PIH had higher levels of serum hs-CRP and mALB than the control group (P<0.01). Serum hs-CRP and mALB levels in the severe preeclampsia group were significantly higher than those in the mild preeclampsia group (P<0.05). ROC curve analysis showed that hs-CRP was a factor of high-risk. Area under the curve was 0.943, and the 95% confidence interval was 0.848-0.974. Detection of serum hs-CRP in patients with PIH can provide references for the prediction of the severity of the disease, and higher level of hs-CRP indicates worse condition.
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1 

Kappelle PJ, de Boer JF, Perton FG, Annema W, de Vries R, Dullaart RP and Tietge UJ: Increased LCAT activity and hyperglycaemia decrease the antioxidative functionality of HDL. Eur J Clin Invest. 42:487–495. 2012. View Article : Google Scholar : PubMed/NCBI

2 

Kintiraki E, Papakatsika S, Kotronis G, Goulis DG and Kotsis V: Pregnancy-induced hypertension. Hormones (Athens). 14:211–223. 2015. View Article : Google Scholar : PubMed/NCBI

3 

Andrews L and Patel N: Correlation of serum lactate dehydrogenase and pregnancy induced hypertension with its adverse outcomes. Int J Res Med Sci. 4:1347–1350. 2016. View Article : Google Scholar

4 

George JN and Amaresh A: Neonatal mortality and morbidity in pregnancy induced hypertension: A prospective observational study. J Evol Med Dent Sci. 3:5238–5246. 2014. View Article : Google Scholar

5 

Sibai BM and Stella CL: Diagnosis and management of atypical preeclampsia-eclampsia. Am J Obstet Gynecol. 200:481.e1–7. 2009. View Article : Google Scholar

6 

Pouta A, Hartikainen AL, Sovio U, Gissler M, Laitinen J, McCarthy MI, Ruokonen A, Elliott P and Järvelin MR: Manifestations of metabolic syndrome after hypertensive pregnancy. Hypertension. 43:825–831. 2004. View Article : Google Scholar : PubMed/NCBI

7 

Zhu H, Liu M, Yu H, Liu X, Zhong Y, Shu J, Fu X, Cai G, Chen X, Geng W, et al: Glycopatterns of urinary protein as new potential diagnosis indicators for diabetic nephropathy. J Diabetes Res. 2017:57280872017. View Article : Google Scholar : PubMed/NCBI

8 

Volanakis JE: Human C-reactive protein: Expression, structure, and function. Mol Immunol. 38:189–197. 2001. View Article : Google Scholar : PubMed/NCBI

9 

Qiu C, Sorensen TK, Luthy DA and Williams MA: A prospective study of maternal serum C-reactive protein (CRP) concentrations and risk of gestational diabetes mellitus. Paediatr Perinat Epidemiol. 18:377–384. 2004. View Article : Google Scholar : PubMed/NCBI

10 

Paternoster DM, Fantinato S, Stella A, Nanhornguè KN, Milani M, Plebani M, Nicolini U and Girolami A: C-reactive protein in hypertensive disorders in pregnancy. Clin Appl Thromb Hemost. 12:330–337. 2006. View Article : Google Scholar : PubMed/NCBI

11 

Liu LS: Writing Group of 2010 Chinese Guidelines for the Management of Hypertension: 2010 Chinese guidelines for the management of hypertension. Zhonghua Xin Xue Guan Bing Za Zhi. 39:579–615. 2011.(In Chinese). PubMed/NCBI

12 

García RG, Celedón J, Sierra-Laguado J, Alarcón MA, Luengas C, Silva F, Arenas-Mantilla M and López-Jaramillo P: Raised C-reactive protein and impaired flow-mediated vasodilation precede the development of preeclampsia. Am J Hypertens. 20:98–103. 2007. View Article : Google Scholar : PubMed/NCBI

13 

Freeman DJ, McManus F, Brown EA, Cherry L, Norrie J, Ramsay JE, Clark P, Walker ID, Sattar N and Greer IA: Short- and long-term changes in plasma inflammatory markers associated with preeclampsia. Hypertension. 44:708–714. 2004. View Article : Google Scholar : PubMed/NCBI

14 

Watanabe K, Naruse K, Tanaka K, Metoki H and Suzuki Y: Outline of definition and classification of ‘pregnancy induced hypertension (PIH)’. Hypertens Res Pregnancy. 1:3–4. 2013. View Article : Google Scholar

15 

El Desh F, El Naggar G, Eid M and Ibrahim E: Measurement of serum sex hormone-binding globulin as an early marker for gestational diabetes. Tanta Med J. 45:14–20. 2017. View Article : Google Scholar

16 

Yousuf O, Mohanty BD, Martin SS, Joshi PH, Blaha MJ, Nasir K, Blumenthal RS and Budoff MJ: High-sensitivity C-reactive protein and cardiovascular disease: A resolute belief or an elusive link? J Am Coll Cardiol. 62:397–408. 2013. View Article : Google Scholar : PubMed/NCBI

17 

Gaikwad KB, Joshi NG and Selkar SP: Study of nitrosative stress in ‘Pregnancy Induced Hypertension’. J Clin Diagn Res. 11:BC06–BC08. 2017.PubMed/NCBI

18 

Niraula A, Lamsal M, Majhi S, Khan SA and Basnet P: Significance of serum uric acid in pregnancy induced hypertension. J Natl Med Assoc. 109:198–202. 2017. View Article : Google Scholar : PubMed/NCBI

19 

Ertas IE, Kahyaoglu S, Yilmaz B, Ozel M, Sut N, Guven MA and Danisman N: Association of maternal serum high sensitive C-reactive protein level with body mass index and severity of pre-eclampsia at third trimester. J Obstet Gynaecol Res. 36:970–977. 2010. View Article : Google Scholar : PubMed/NCBI

20 

Wang L, Liu ZQ, Huo YQ, Yao LJ, Wei XG and Wang YF: Change of hs-CRP, sVCAM-1, NT-proBNP levels in patients with pregnancy-induced hypertension after therapy with magnesium sulfate and nifedipine. Asian Pac J Trop Med. 6:897–901. 2013. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Chen H, Zhang J, Qin F, Chen X and Jiang X: Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome. Exp Ther Med 16: 619-622, 2018.
APA
Chen, H., Zhang, J., Qin, F., Chen, X., & Jiang, X. (2018). Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome. Experimental and Therapeutic Medicine, 16, 619-622. https://doi.org/10.3892/etm.2018.6246
MLA
Chen, H., Zhang, J., Qin, F., Chen, X., Jiang, X."Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome". Experimental and Therapeutic Medicine 16.2 (2018): 619-622.
Chicago
Chen, H., Zhang, J., Qin, F., Chen, X., Jiang, X."Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome". Experimental and Therapeutic Medicine 16, no. 2 (2018): 619-622. https://doi.org/10.3892/etm.2018.6246
Copy and paste a formatted citation
x
Spandidos Publications style
Chen H, Zhang J, Qin F, Chen X and Jiang X: Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome. Exp Ther Med 16: 619-622, 2018.
APA
Chen, H., Zhang, J., Qin, F., Chen, X., & Jiang, X. (2018). Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome. Experimental and Therapeutic Medicine, 16, 619-622. https://doi.org/10.3892/etm.2018.6246
MLA
Chen, H., Zhang, J., Qin, F., Chen, X., Jiang, X."Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome". Experimental and Therapeutic Medicine 16.2 (2018): 619-622.
Chicago
Chen, H., Zhang, J., Qin, F., Chen, X., Jiang, X."Evaluation of the predictive value of high sensitivity C-reactive protein in pregnancy-induced hypertension syndrome". Experimental and Therapeutic Medicine 16, no. 2 (2018): 619-622. https://doi.org/10.3892/etm.2018.6246
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