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Analyses of the efficacy of percutaneous kyphoplasty and alendronate sodium on thoracolumbar vertebral fracture and the risk factors of fracture

  • Authors:
    • Pengbin Li
    • Wenjuan Tang
    • Biao Che
    • Kai Wang
    • Kai Zou
    • Zheng Jin
    • Feng Zhou
    • Yan Zhuang
  • View Affiliations / Copyright

    Affiliations: Department of Orthopedics, General Hospital of The Yangtze River Shipping and Wuhan Brain Hospital, Wuhan, Hubei 430010, P.R. China, Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430010, P.R. China, Department of Orthopedics, The Affiliated Jiangyin Hospital of Southeast University Medical College, Wuxi, Jiangsu 214400, P.R. China
  • Pages: 679-684
    |
    Published online on: June 1, 2018
       https://doi.org/10.3892/etm.2018.6247
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Abstract

The present study investigated the efficacy of percutaneous kyphoplasty and alendronate sodium on thoracolumbar vertebral fracture, and the risk factors leading to the recurrence of fracture. In the present study, a total of 80 patients with thoracolumbar vertebral fracture who were admitted to the Affiliated Jiangyin Hospital of Southeast University Medical College between January 2014 and March 2016 for combination treatment of percutaneous kyphoplasty and alendronate sodium were enrolled. According to the recurrence of fracture, the patients were divided into two groups, the observation group (patients with fracture recurrence, n=40) and control group (patients with no fracture recurrence, n=40). All patients participated in a 1‑year follow‑up. The recurrence of fracture and the site of fracture were identified through the clinical symptoms and examination of the spine using magnetic resonance imaging. In addition, comparisons of the time of alleviation in numbness of lower limb and that in pains in waist and legs were carried out. Furthermore, statistics on the adverse reactions during intervention in the two groups were also collected; changes in visual analogue scale (VAS) and Oswestry Disability Index (ODI) of pains at different time points in two groups were also observed. One‑way analysis and multivariate analysis were performed to identify the relevant risk factors. Alleviation time in numbness of lower legs in patients of the control group was significantly earlier than that in the observation group (P<0.05) and the alleviation time in pains of the waist and legs of patients in the control group was also significantly earlier than that in the observation group (P<0.05). Furthermore, the incidence rates of abdominal pain, diarrhea, constipation and hypocalcemiain in the control group were also significantly lower compared with those in the observation group (P<0.05). One week, one month and one year after operation, the scores of VAS of pains and ODI in the control group were significantly lower compared with those in the observation group in the same period (P<0.05). Lower preoperative bone density and exosmosis of bone cement in treatment were the independent risk factors leading to the recurrence of fracture. For patients with thoracolumbar vertebral fracture who received the combination treatment of percutaneous kyphoplasty and alendronate sodium, there underlies an important correlation between the recurrence rate of fracture and the preoperative bone density as well as the exosmosis of bone cement in operation.
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1 

Semaan H, Obri T, Bazerbashi M, Paull D, Liu X, Sarrouj M and Elgafy H: Clinical outcome and subsequent sequelae of cement extravasation after percutaneous kyphoplasty and vertebroplasty: A comparative review. Acta Radiol. Jan 1. 2017, (Epub ahead of print). PubMed/NCBI

2 

Niu J, Song D, Zhou H, Meng Q, Meng B and Yang H: Percutaneous kyphoplasty for the treatment of osteoporotic vertebral fractures with intravertebral fluid or air: A comparative study. Clin Spine Surg. 30:367–373. 2017. View Article : Google Scholar : PubMed/NCBI

3 

Filippiadis DK, Marcia S, Masala S, Deschamps F and Kelekis A: Percutaneous vertebroplasty and kyphoplasty: Current status, new developments and old controversies. Cardiovasc Intervent Radiol. 40:1815–1823. 2017. View Article : Google Scholar : PubMed/NCBI

4 

Rajasekaran S, Kanna RM, Schnake KJ, Vaccaro AR, Schroeder GD, Sadiqi S and Oner C: Osteoporotic thoracolumbar Fractures-How are they different?-Classification and treatment algorithm. J Orthop Trauma. 31(Suppl 4): S49–S56. 2017. View Article : Google Scholar : PubMed/NCBI

5 

Liu T, Li Z, Su Q and Hai Y: Cement leakage in osteoporotic vertebral compression fractures with cortical defect using high-viscosity bone cement during unilateral percutaneous kyphoplasty surgery. Medicine (Baltimore). 96:e72162017. View Article : Google Scholar : PubMed/NCBI

6 

Masoudi MS, Haghnegahdar A, Ghaffarpasand F and Ilami G: Functional recovery following early kyphoplasty versus conservative management in stable thoracuolumbar fractures in parachute jumpers: A randomized clinical trial. Clin Spine Surg. 30:E1066–E1073. 2017. View Article : Google Scholar : PubMed/NCBI

7 

Yang P, Lin J, Liu H, Shen H and Yang HL: Primary bone mantle cell lymphomas with multiple vertebral compression fractures: A case report. Oncol Lett. 13:1288–1292. 2017. View Article : Google Scholar : PubMed/NCBI

8 

Sun ZY, Li XF, Zhao H, Lin J, Qian ZL, Zhang ZM and Yang HL: Percutaneous balloon kyphoplasty in treatment of painful osteoporotic occult vertebral fracture: A retrospective study of 89 cases. Med Sci Monit. 23:1682–1690. 2017. View Article : Google Scholar : PubMed/NCBI

9 

Rosenbaum BP, Kshettry VR, Kelly ML, Mroz TE and Weil RJ: Trends in inpatient vertebroplasty and kyphoplasty volume in the united states, 2005–2011: Assessing the impact of randomized controlled trials. Clin Spine Surg. 30:E276–E282. 2017. View Article : Google Scholar : PubMed/NCBI

10 

Lin D, Hao J, Li L, Wang L, Zhang H, Zou W and Lian K: Effect of bone cement volume fraction on adjacent vertebral fractures after unilateral percutaneous kyphoplasty. Clin Spine Surg. 30:E270–E275. 2017. View Article : Google Scholar : PubMed/NCBI

11 

Pesenti S, Graillon T, Mansouri N, Adetchessi T, Tropiano P, Blondel B and Fuentes S: Use of pedicle percutaneous cemented screws in the management of patients with poor bone stock. Neurochirurgie. 62:306–311. 2016.(In French). View Article : Google Scholar : PubMed/NCBI

12 

Wu YS, Zhang H, Zheng WH, Feng ZH, Chen ZX and Lin Y: Hidden blood loss and the influential factors after percutaneous kyphoplasty surgery. Eur Spine J. 26:1878–1883. 2017. View Article : Google Scholar : PubMed/NCBI

13 

Gonschorek O, Hauck S, Weiss T and Buhren V: Percutaneous vertebral augmentation in fragility fractures-indications and limitations. Eur J Trauma Emerg Surg. 43:9–17. 2017. View Article : Google Scholar : PubMed/NCBI

14 

Beall DP, Parsons B and Burner S: Technical strategies and anatomic considerations for an extrapedicular modified inferior endplate access to thoracic and lumbar vertebral bodies. Pain Physician. 19:593–601. 2016.PubMed/NCBI

15 

Dmytriw AA, Talla K and Smith R: Percutaneous sacroplasty for the management of painful pathologic fracture in a multiple myeloma patient: Case report and review of the literature. Neuroradiol J. 30:80–83. 2017. View Article : Google Scholar : PubMed/NCBI

16 

Cheng X, Long HQ, Xu JH, Huang YL and Li FB: Comparison of unilateral versus bilateral percutaneous kyphoplasty for the treatment of patients with osteoporosis vertebral compression fracture (OVCF): A systematic review and meta-analysis. Eur Spine J. 25:3439–3449. 2016. View Article : Google Scholar : PubMed/NCBI

17 

Riva A, Togni S, Giacomelli L, Franceschi F, Eggenhoffner R, Feragalli B, Belcaro G, Cacchio M, Shu H and Dugall M: Effects of a curcumin-based supplementation in asymptomatic subjects with low bone density: A preliminary 24-week supplement study. Eur Rev Med Pharmacol Sci. 21:1684–1689. 2017.PubMed/NCBI

18 

Yang H, Liu H, Wang S, Wu K, Meng B and Liu T: Review of percutaneous kyphoplasty in china. Spine (Phila Pa 1976). 41(Suppl 19): B52–B58. 2016. View Article : Google Scholar : PubMed/NCBI

19 

Yaltirik K, Ashour AM, Reis CR, Ozdogan S and Atalay B: Vertebral augmentation by kyphoplasty and vertebroplasty: 8 years experience outcomes and complications. J Craniovertebr Junction Spine. 7:153–160. 2016. View Article : Google Scholar : PubMed/NCBI

20 

Korovessis P, Mpountogianni E and Syrimpeis V: Percutaneous pedicle screw fixation plus kyphoplasty for thoracolumbar fractures A2, A3 and B2. Eur Spine J. 26:1492–1498. 2017. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Li P, Tang W, Che B, Wang K, Zou K, Jin Z, Zhou F and Zhuang Y: Analyses of the efficacy of percutaneous kyphoplasty and alendronate sodium on thoracolumbar vertebral fracture and the risk factors of fracture. Exp Ther Med 16: 679-684, 2018.
APA
Li, P., Tang, W., Che, B., Wang, K., Zou, K., Jin, Z. ... Zhuang, Y. (2018). Analyses of the efficacy of percutaneous kyphoplasty and alendronate sodium on thoracolumbar vertebral fracture and the risk factors of fracture. Experimental and Therapeutic Medicine, 16, 679-684. https://doi.org/10.3892/etm.2018.6247
MLA
Li, P., Tang, W., Che, B., Wang, K., Zou, K., Jin, Z., Zhou, F., Zhuang, Y."Analyses of the efficacy of percutaneous kyphoplasty and alendronate sodium on thoracolumbar vertebral fracture and the risk factors of fracture". Experimental and Therapeutic Medicine 16.2 (2018): 679-684.
Chicago
Li, P., Tang, W., Che, B., Wang, K., Zou, K., Jin, Z., Zhou, F., Zhuang, Y."Analyses of the efficacy of percutaneous kyphoplasty and alendronate sodium on thoracolumbar vertebral fracture and the risk factors of fracture". Experimental and Therapeutic Medicine 16, no. 2 (2018): 679-684. https://doi.org/10.3892/etm.2018.6247
Copy and paste a formatted citation
x
Spandidos Publications style
Li P, Tang W, Che B, Wang K, Zou K, Jin Z, Zhou F and Zhuang Y: Analyses of the efficacy of percutaneous kyphoplasty and alendronate sodium on thoracolumbar vertebral fracture and the risk factors of fracture. Exp Ther Med 16: 679-684, 2018.
APA
Li, P., Tang, W., Che, B., Wang, K., Zou, K., Jin, Z. ... Zhuang, Y. (2018). Analyses of the efficacy of percutaneous kyphoplasty and alendronate sodium on thoracolumbar vertebral fracture and the risk factors of fracture. Experimental and Therapeutic Medicine, 16, 679-684. https://doi.org/10.3892/etm.2018.6247
MLA
Li, P., Tang, W., Che, B., Wang, K., Zou, K., Jin, Z., Zhou, F., Zhuang, Y."Analyses of the efficacy of percutaneous kyphoplasty and alendronate sodium on thoracolumbar vertebral fracture and the risk factors of fracture". Experimental and Therapeutic Medicine 16.2 (2018): 679-684.
Chicago
Li, P., Tang, W., Che, B., Wang, K., Zou, K., Jin, Z., Zhou, F., Zhuang, Y."Analyses of the efficacy of percutaneous kyphoplasty and alendronate sodium on thoracolumbar vertebral fracture and the risk factors of fracture". Experimental and Therapeutic Medicine 16, no. 2 (2018): 679-684. https://doi.org/10.3892/etm.2018.6247
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