Blood platelet and serum bilirubin in the diagnosis of central serous chorioretinopathy

Zhang,Qiang; Wang,Wei; Dong,Changxia

doi:10.3892/etm.2018.6267

Blood platelet and serum bilirubin in the diagnosis of central serous chorioretinopathy

Authors:
- Qiang Zhang
- Wei Wang
- Changxia Dong
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Affiliations: Department of Ophthalmology, Yantai Hospital of Traditional Chinese Medicine, Yantai, Shandong 264000, P.R. China, Department of Ophthalmology, Yantai Yeda Hospital, Yantai, Shandong 264000, P.R. China, Department of Ophthalmology, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China
Published online on: June 7, 2018 https://doi.org/10.3892/etm.2018.6267
Pages: 874-878

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Abstract

Diagnostic value of blood platelet (PLT) and serum total bilirubin (TBIL) for central serous chorioretinopathy (CSC) was investigated. A total of 537 patients with CSC and 182 people with normal physical conditions were selected from June 2012 to August 2016. The 537 patients included 294 males and 243 females with an average age of 45.5±17.8 years, and all patients were treated in the Department of Ophthalmology of Yantai Hospital of Traditional Chinese Medicine and the Department of Ophthalmology of Yantai Liuhuangding Hospital. Clinical data of the patients were retrospectively analyzed. The 182 people with normal physical conditions included 103 males and 79 females with an average age of 43.6±15.2 years, and they were set as the control group. PLT and TBIL tests at admission and after treatment were collected and compared between CSC and the control group to analyze the diagnostic values of PLT and TBIL for CSC. PLT level in the CSC group was significantly higher than that in the control group, but TBIL level in the CSC group was significantly lower than that in the control group (p<0.05). Linear correlation analysis showed that PLT was a risk factor for CSC, and TBIL was a protective factor for CSC. The sensitivity of PLT and TBIL in diagnosis of CSC was 75.2 and 72.7%, respectively, and the specificity of PLT and TBIL in diagnosis of CSC was 65.8 and 63.3%, respectively. PLT of CSC patients was significantly higher than that of the control group, and TBIL of CSC patients was significantly lower than that of the control group, but they both gradually reduced to normal levels after treatment, which can be regarded as the index for the clinical diagnosis of CSC in the future.

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