Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
August-2018 Volume 16 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
August-2018 Volume 16 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

An analysis on treatment effect of blue light phototherapy combined with Bifico in treating neonatal hemolytic jaundice

  • Authors:
    • Yan Jiao
    • Yuting Jin
    • Huanhuan Meng
    • Meizhang Wen
  • View Affiliations / Copyright

    Affiliations: Department of Neonatology, People's Hospital of Rizhao, Rizhao, Shandong 276826, P.R. China
    Copyright: © Jiao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1360-1364
    |
    Published online on: June 21, 2018
       https://doi.org/10.3892/etm.2018.6340
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

This study aimed to discuss and evaluate the clinical effect of blue light phototherapy combined with bifico in treating neonatal hemolytic jaundice. One hundred and twenty cases with neonatal hemolytic jaundice were randomly divided into treatment group and control group, 60 cases in each group. Neonatal patients in the control group were treated with traditional treatment, including administration of enzyme inducer phenobarbital and blue light phototherapy for 8 consecutive hours every day. Neonatal patients in the treatment group received bifico orally based on traditional treatment. Clinical effects of the two groups were observed after one course of treatment (7 days as one course). During the first course, serum bilirubin level in the treatment group treated with blue light phototherapy combined with bifico declined more rapidly (P<0.01) and more significantly (P<0.01) than that in the control group, and the mean time for eliminating jaundice was significantly reduced (P<0.05). The total effective rate was 91.67% in the treatment group, while that was 85.00% in the control group, which suggested that the treatment effect of the treatment group was better than that of the control group and the difference between the two groups was statistically significant (P<0.05). Compared with traditional treatment, the treatment effect of blue light phototherapy combined with bifico in treating neonatal hemolytic jaundice is significantly improved and the speed of eliminating jaundice is also higher. Thus, it is worthy to be applied in clinical practice.
View Figures
View References

1 

Menon M, Sreejyothi G and Raveendranath K: Incidence of early neonatal hyperbilirubinemia in ABO incompatibility and cord bilirubin as a predictor for phototherapy. Pediatric Review. Int J Pediatr Res. 3:2016.

2 

Wang G, Wang J, Huang N and Yu F: The study on clinical value of the detection about serum and Unconjugated Bilirubin in diagnosis of neonatal jaundice. Pak J Pharm Sci. 29 Suppl 1:339–341. 2016.PubMed/NCBI

3 

Wong RJ, Bhutani VK and Stevenson DK: The importance of hemolysis and its clinical detection in neonates with hyperbilirubinemia. Curr Pediatr Rev. Aug 7–2017.(Epub ahead of print). doi: 10.2174/1573396313666170807121444. View Article : Google Scholar : PubMed/NCBI

4 

Olusanya BO, Iskander IF, Slusher TM and Wennberg RP: A decision-making tool for exchange transfusions in infants with severe hyperbilirubinemia in resource-limited settings. J Perinatol. 36:338–341. 2016. View Article : Google Scholar : PubMed/NCBI

5 

Ramy N, Ghany EA, Alsharany W, Nada A, Darwish RK, Rabie WA and Aly H: Jaundice, phototherapy and DNA damage in full-term neonates. J Perinatol. 36:132–136. 2016. View Article : Google Scholar : PubMed/NCBI

6 

Lee BK, Le Ray I, Sun JY, Wikman A, Reilly M and Johansson S: Haemolytic and nonhaemolytic neonatal jaundice have different risk factor profiles. Acta Paediatr. 105:1444–1450. 2016. View Article : Google Scholar : PubMed/NCBI

7 

Chen M, Zeng Y and Chen X: Effects of maternal serum IgG anti-A (B) and neonatal direct anti globulin red blood cell antibody expression on the occurrence and development of neonatal ABO haemolysis. Biomed Res. 28:1855–1858. 2017.

8 

van Toorn R, Brink P, Smith J, Ackermann C and Solomons R: Bilirubin-induced neurological dysfunction: A clinico-radiological-neurophysiological correlation in 30 consecutive children. J Child Neurol. 31:1579–1583. 2016. View Article : Google Scholar : PubMed/NCBI

9 

Babu TA, Bhat BV and Joseph NM: Neurobehavior of term neonates with neonatal hyperbilirubinemia. J Pediatr Neurosci. 8:11–14. 2013. View Article : Google Scholar : PubMed/NCBI

10 

Mreihil K, Benth JS, Stensvold HJ, Nakstad B and Hansen TW: Norwegian NICU Phototherapy Study Group; and the Norwegian Neonatal Network: Phototherapy is commonly used for neonatal jaundice but greater control is needed to avoid toxicity in the most vulnerable infants. Acta Paediatr. Nov 8–2017.(Epub ahead of print. doi: 10.1111/apa.14141.

11 

Waterham M, Bhatia R, Donath S, Molesworth C, Tan K and Stewart M: Phototherapy in transport for neonates with unconjugated hyperbilirubinaemia. J Paediatr Child Health. 52:67–71. 2016. View Article : Google Scholar : PubMed/NCBI

12 

Woodgate P and Jardine LA: Neonatal jaundice: phototherapy. BMJ Clin Evid. 2015:03192015.PubMed/NCBI

13 

Slusher TM, Vreman HJ, Olusanya BO, Wong RJ, Brearley AM, Vaucher YE and Stevenson DK: Safety and efficacy of filtered sunlight in treatment of jaundice in African neonates. Pediatrics. 133:e1568–e1574. 2014. View Article : Google Scholar : PubMed/NCBI

14 

Edris AA, Ghany EA, Razek AR and Zahran AM: The role of intensive phototherapy in decreasing the need for exchange transfusion in neonatal jaundice. J Pak Med Assoc. 64:5–8. 2014.PubMed/NCBI

15 

Christensen RD, Yaish HM, Nussenzveig RH, Reading NS, Agarwal AM, Eggert LD and Prchal JT: Acute kernicterus in a neonate with O/B blood group incompatibility and a mutation in SLC4A1. Pediatrics. 132:e531–e534. 2013. View Article : Google Scholar : PubMed/NCBI

16 

Kaplan M, Bromiker R and Hammerman C: Hyperbilirubinemia, hemolysis, and increased bilirubin neurotoxicity. Semin Perinatol. 38:429–437. 2014. View Article : Google Scholar : PubMed/NCBI

17 

Olusanya BO, Osibanjo FB and Slusher TM: Risk factors for severe neonatal hyperbilirubinemia in low and middle-income countries: A systematic review and meta-analysis. PLoS One. 10:e01172292015. View Article : Google Scholar : PubMed/NCBI

18 

Shen L, Wang H and Guo Y: Retrospective analysis of the pathogeny and treatment for hyperbilirubinemia in 162 newborns. Int J Pathol Clin Med. 33:2013.doi: 10.3969/j.issn.1673-2588.2013.02.008.

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Jiao Y, Jin Y, Meng H and Wen M: An analysis on treatment effect of blue light phototherapy combined with Bifico in treating neonatal hemolytic jaundice. Exp Ther Med 16: 1360-1364, 2018.
APA
Jiao, Y., Jin, Y., Meng, H., & Wen, M. (2018). An analysis on treatment effect of blue light phototherapy combined with Bifico in treating neonatal hemolytic jaundice. Experimental and Therapeutic Medicine, 16, 1360-1364. https://doi.org/10.3892/etm.2018.6340
MLA
Jiao, Y., Jin, Y., Meng, H., Wen, M."An analysis on treatment effect of blue light phototherapy combined with Bifico in treating neonatal hemolytic jaundice". Experimental and Therapeutic Medicine 16.2 (2018): 1360-1364.
Chicago
Jiao, Y., Jin, Y., Meng, H., Wen, M."An analysis on treatment effect of blue light phototherapy combined with Bifico in treating neonatal hemolytic jaundice". Experimental and Therapeutic Medicine 16, no. 2 (2018): 1360-1364. https://doi.org/10.3892/etm.2018.6340
Copy and paste a formatted citation
x
Spandidos Publications style
Jiao Y, Jin Y, Meng H and Wen M: An analysis on treatment effect of blue light phototherapy combined with Bifico in treating neonatal hemolytic jaundice. Exp Ther Med 16: 1360-1364, 2018.
APA
Jiao, Y., Jin, Y., Meng, H., & Wen, M. (2018). An analysis on treatment effect of blue light phototherapy combined with Bifico in treating neonatal hemolytic jaundice. Experimental and Therapeutic Medicine, 16, 1360-1364. https://doi.org/10.3892/etm.2018.6340
MLA
Jiao, Y., Jin, Y., Meng, H., Wen, M."An analysis on treatment effect of blue light phototherapy combined with Bifico in treating neonatal hemolytic jaundice". Experimental and Therapeutic Medicine 16.2 (2018): 1360-1364.
Chicago
Jiao, Y., Jin, Y., Meng, H., Wen, M."An analysis on treatment effect of blue light phototherapy combined with Bifico in treating neonatal hemolytic jaundice". Experimental and Therapeutic Medicine 16, no. 2 (2018): 1360-1364. https://doi.org/10.3892/etm.2018.6340
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team