Therapeutic effect of MIPPSO in the thoracolumbar vertebra fracture

Ren,Kewei; Tang,Jilei; Jiang,Xuefeng; Nong,Luming; Gu,Yanqing

doi:10.3892/etm.2018.6368

September-2018 Volume 16 Issue 3

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September-2018 Volume 16 Issue 3

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Article Open Access

Therapeutic effect of MIPPSO in the thoracolumbar vertebra fracture

Authors:
- Kewei Ren
- Jilei Tang
- Xuefeng Jiang
- Luming Nong
- Yanqing Gu
View Affiliations / Copyright

Affiliations: Department of Orthopedics, Τhe Affiliated Jiangyin Hospital of Southeast University Medical School, Jiangyin, Jiangsu 214400, P.R. China, Department of Orthopedics, Qidong People's Hospital, Nantong, Jiangsu 226200, P.R. China, Department of Orthopedics, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, Jiangsu 213003, P.R. China, Department of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, P.R. China

Copyright: © Ren et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 1784-1789
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Published online on: June 28, 2018

https://doi.org/10.3892/etm.2018.6368
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Abstract

The purpose of this study was to compare the efficacy of minimally invasive percutaneous pedicle screw osteosynthesis (MIPPSO) and traditional open pedicle screw osteosynthesis (TOPSO) in the treatment of thoracolumbar vertebra fracture. A retrospective case-control study was conducted in 120 patients with thoracolumbar vertebral fractures treated in the Affiliated Jiangyin Hospital of Southeast University Medical School (Jiangyin, China) from January 2013 to September 2014. They were randomly divided into two groups: MIPPSO and TOPSO groups with 60 cases in each group. The operation time, blood loss, incision length, post-operative bed rest time, hospital stay, visual analogue scale (VAS) pain scores and Oswestry disability index (ODI) scores before and after operation were recorded and analyzed. Inflammatory indexes including serum C-reactive protein (CRP) and creatine kinase (CK), the anterior vertebral height ratio and kyphosis Cobb's angle changes were also observed. The basic data of the two groups were similar, and there was no significant difference in the operation time between the two groups. The perioperative blood loss, length of incision, bed rest time and total hospital stay in the minimally invasive group were less than those in the open group. Levels of post‑operative inflammation indicators such as CRP and CK were significantly higher than those of pre-operative (P<0.05), which was more obvious in the TOPSO group (P<0.05). VAS, ODI scores, anterior vertebral height and Cobb's angle were significantly improved at three days, one and 12 months after surgery compared with those before operation. MIPPSO for the treatment of thoracolumbar fractures can achieve similar clinical effects with traditional incision surgery. In addition, it has the advantages of less trauma, less bleeding and shorter post-operative bed rest time and hospital stay.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Therapeutic effect of MIPPSO in the thoracolumbar vertebra fracture

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Abstract

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