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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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September-2018 Volume 16 Issue 3

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Review Open Access

Advances in CLARITY‑based tissue clearing and imaging (Review)

Hao Du, Peihong Hou, Wenbo Zhang, Qiyu Li
Pages: 1567-1576
Published online on: 29 June 2018

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Review Open Access

Fluorescent contrast agents for tumor surgery (Review)

Qi Xiao, Tianming Chen, Shilin Chen
Pages: 1577-1585
Published online on: 04 July 2018

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Article Open Access

Combined antitumor effects of P‑5m octapeptide and 5‑fluorouracil on a murine model of H22 hepatoma ascites Corrigendum in /10.3892/etm.2018.6971

Xiao Han, Liping An, Dongmei Yan, Hiroshi Matsuura, Weiguang Ding, Mengchuan Zhang, Guangyu Xu, Ying Sun, Guangxin Yuan, Manli Wang, Nanxi Zhao, Jingbo Sun, Xun Zhu, Peige Du
Pages: 1586-1592
Published online on: 06 July 2018

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Article Open Access

Evaluation of the safety of MRI scans in patients undergoing dual-chamber pacemaker implantation

Minchao Xiong, Nian Zhao, Yan Qin, Peng Min, Hong Peng, Yong Zhang, Bin Fan
Pages: 1593-1596
Published online on: 02 July 2018

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Article Open Access

Use of ozonated water as a new therapeutic approach to solve current concerns around antitumor treatment

Kohei Kuroda, Masamiti Yamashita, Yusuke Murahata, Kazuo Azuma, Tomohiro Osaki, Takeshi Tsuka, Norihiko Ito, Tomohiro Imagawa, Yoshiharu Okamoto
Pages: 1597-1602
Published online on: 06 July 2018

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Article Open Access

Efficacy, functional outcome and post‑operative complications of total abdominal colectomy with ileorectal anastomosis vs. segmental colectomy in hereditary non‑polyposis colorectal cancer

Jie Sun, Mingjie Dong, Xiaoping Xiao
Pages: 1603-1612
Published online on: 29 June 2018

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Article Open Access

Microarray data analysis to identify differentially expressed genes and biological pathways associated with asthma

Shanshan Qi, Guanghui Liu, Xiang Dong, Nan Huang, Wenjing Li, Hao Chen
Pages: 1613-1620
Published online on: 28 June 2018

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Article Open Access

HOXD10 silencing suppresses human fibroblast‑like synoviocyte migration in rheumatoid arthritis via downregulation of the p38/JNK pathway

Luan Luan, Yingying Ma, Lihua Zhang
Pages: 1621-1628
Published online on: 09 July 2018

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Article Open Access

MicroRNA‑138 inhibits SOX12 expression and the proliferation, invasion and migration of ovarian cancer cells

Miaomiao Qu, Yongning Zhu, Meng Jin
Pages: 1629-1638
Published online on: 29 June 2018

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Article Open Access

Preparation and characterization of norcantharidin liposomes modified with stearyl glycyrrhetinate

Jing Zhu, Wei Zhang, Dandan Wang, Suzhen Li, Wei Wu
Pages: 1639-1646
Published online on: 06 July 2018

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Article Open Access

Effect of naproxen on proliferation and differentiation of primary cell cultures isolated from human cartilage tissue

Numan Karaarslan, Ahmet Guray Batmaz, Ibrahim Yilmaz, Hanefi Ozbek, Tezcan Caliskan, Duygu Yasar Sirin, Necati Kaplan, Kadir Oznam, Ozkan Ates
Pages: 1647-1654
Published online on: 26 June 2018

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Article Open Access

Combination therapy with BMP‑2 and psoralen enhances fracture healing in ovariectomized mice

Kui Huang, Guofeng Wu, Ji Zou, Songming Peng
Pages: 1655-1662
Published online on: 26 June 2018

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Article Open Access

MicroRNA‑101‑3p inhibits proliferation in retinoblastoma cells by targeting EZH2 and HDAC9

Qifang Jin, Wenfeng He, Leifeng Chen, Yang Yang, Ke Shi, Zhipeng You
Pages: 1663-1670
Published online on: 04 July 2018

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Article Open Access

Role of ALK5/SMAD2/3 signaling in the regulation of NOX expression in cerebral ischemia/reperfusion injury

Zheng Lou, Ai‑Ping Wang, Xiao‑Ming Duan, Guo‑Huang Hu, Mei‑Ling Zuo, Zhong‑Bao Yang
Pages: 1671-1678
Published online on: 29 June 2018

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Article Open Access

Relationship between serum levels of miR-204 and clinical features of patients with lumbar disc herniation - an analysis based on 1,589 cases

Jun Peng, Yingjie Liu, Yang Zong, Yulin Zhan
Pages: 1679-1684
Published online on: 27 June 2018

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Article Open Access

Estrogen relaxes gastric muscle cells via a nitric oxide‑ and cyclic guanosine monophosphate‑dependent mechanism: A sex‑associated differential effect

Othman A. Al‑Shboul, Mona S. Nazzal, Ayman G. Mustafa, Ahmed N. Al‑Dwairi, Mohammad A. Alqudah, Amal Abu Omar, Mahmoud A. Alfaqih, Mohammad I. Alsalem
Pages: 1685-1692
Published online on: 04 July 2018

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Article Open Access

Decreased expression of microRNA‑214 contributes to imatinib mesylate resistance of chronic myeloid leukemia patients by upregulating ABCB1 gene expression

Jing Jin, Jia Yao, Fang Yue, Zhaoying Jin, Dan Li, Shan Wang
Pages: 1693-1700
Published online on: 04 July 2018

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Article Open Access

Expression of miR‑376 in blood of pregnant women with preeclampsia and its effect on 25‑hydroxyvitamin D

Jinlan Li, Jiangdong Du, Zhan Wang, Chenghong Wang, Jianhua Bai, Su Zhang
Pages: 1701-1706
Published online on: 03 July 2018

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Article Open Access

Identification of miRNAs associated with the mechanical response of hepatic stellate cells by miRNA microarray analysis

Suhong Yi, Xia Qin, Xu Luo, Yi Zhang, Zhijun Liu, Liang Zhu
Pages: 1707-1714
Published online on: 29 June 2018

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Article Open Access

Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA‑induced cirrhotic rats

Lei Luo, Zhang Zhou, Juan Xue, Yao Wang, Juan Zhang, Xin Cai, Yuqing Liu, Fan Yang
Pages: 1715-1722
Published online on: 09 July 2018

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Article Open Access

Flexible ureteroscopic holmium laser lithotripsy with PolyScope for senile patients with renal calculi

Ke Xu, Jie Ding, Bowen Shi, Yanyuan Wu, Yunteng Huang
Pages: 1723-1728
Published online on: 28 June 2018

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Article Open Access

Effects of transplanted adipose derived stem cells on the expressions of α‑SMA and DCN in fibroblasts of hypertrophic scar tissues in rabbit ears

Haihan Chu, Yunpeng Wang, Xiuchun Wang, Xianhui Song, Huaqing Liu, Xue Li
Pages: 1729-1734
Published online on: 29 June 2018

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Article Open Access

Histopathological changes and onset of severe hepatic steatosis in rats fed a choline‑free diet

Theodore Karatzas, Nikolaos Sikalias, Dimitrios Mantas, Apostolos Papalois, Konstantinos Alexiou, Lamprini Mountzalia, Gregory Kouraklis
Pages: 1735-1742
Published online on: 29 June 2018

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Article Open Access

Effects of different doses of dexmedetomidine on analgesic efficacy and inflammatory cytokines in patients undergoing laparoscopic surgery

Zhigang Wan, Jie Wang, Hui Cao, Lili Wu
Pages: 1743-1746
Published online on: 26 June 2018

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Article Open Access

Lund exhaust on hemodynamic parameters and inflammatory mediators in patients undergoing cardiac valve replacement under cardiopulmonary bypass

Jihong Zhu, Weimin Zhang, Guoying Shen, Xin Yu, Jige Guo, Taidi Zhong
Pages: 1747-1752
Published online on: 26 June 2018

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Article Open Access

Early ultrasound-guided percutaneous catheter drainage in the treatment of severe acute pancreatitis with acute fluid accumulation

Huazhi Li, Yongzhe Wu, Chen Xu, Hongchao An, Chunhai Guo, Hongli Cui
Pages: 1753-1757
Published online on: 03 July 2018

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Article Open Access

Gambogic acid regulates the migration and invasion of colorectal cancer via microRNA‑21‑mediated activation of phosphatase and tensin homolog

Guangyi Gao, Yinzhu Bian, Hanqing Qian, Mi Yang, Jing Hu, Li Li, Lixia Yu, Baorui Liu, Xiaoping Qian
Pages: 1758-1765
Published online on: 06 July 2018

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Article Open Access

Serum anion gap on admission predicts intensive care unit mortality in patients with aortic aneurysm

Qinchang Chen, Qingui Chen, Lingling Li, Xixia Lin, Shih‑I Chang, Yonghui Li, Zhenluan Tian, Wei Liu, Kai Huang
Pages: 1766-1777
Published online on: 02 July 2018

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Article Open Access

Effects of dexmedetomidine hydrochloride on hemodynamics, postoperative analgesia and cognition in cesarean section

Dehua Kong, Jianhua Bai, Suqiao Ma, Cong Li, Lina Yang, Xiangang Kong
Pages: 1778-1783
Published online on: 27 June 2018

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Article Open Access

Therapeutic effect of MIPPSO in the thoracolumbar vertebra fracture

Kewei Ren, Jilei Tang, Xuefeng Jiang, Luming Nong, Yanqing Gu
Pages: 1784-1789
Published online on: 28 June 2018

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Article Open Access

A meta‑analysis on anterior cruciate ligament reconstruction: Is modified transtibial technique inferior to independent drilling techniques?

Qunhu Zhang, Yu Kou, Zhen Yuan
Pages: 1790-1799
Published online on: 03 July 2018

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Article Open Access

Pirfenidone suppresses bleomycin‑induced pulmonary fibrosis and periostin expression in rats

Xiaoxia Song, Wencheng Yu, Fang Guo
Pages: 1800-1806
Published online on: 29 June 2018

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Article Open Access

Dynamic expression of matrix metalloproteinases 2, 9 and 13 in ovariectomy‑induced osteoporosis rats

Xuefeng Zheng, Yuanyuan Zhang, Shiming Guo, Wenming Zhang, Jinyun Wang, Yanping Lin
Pages: 1807-1813
Published online on: 27 June 2018

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Article Open Access

Downregulation of microRNA‑1 attenuates glucose‑induced apoptosis by regulating the liver X receptor α in cardiomyocytes

Yongxia Cheng, Wei Zhao, Xiaodong Zhang, Lixin Sun, Heran Yang, Ying Wang, Yong Cao, Yanhui Chu, Guibo Liu
Pages: 1814-1824
Published online on: 02 July 2018

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Article Open Access

Fmr1 protects cardiomyocytes against lipopolysaccharide‑induced myocardial injury

Jiasheng Bao, Chen Ye, Zhelan Zheng, Zhengwen Zhou
Pages: 1825-1833
Published online on: 02 July 2018

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Article Open Access

Lycium barbarum polysaccharides attenuates the apoptosis of hippocampal neurons induced by sevoflurane

Yuhai Xie, Xuejun Wang
Pages: 1834-1840
Published online on: 09 July 2018

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Article Open Access

Integrated analysis of key mRNAs and lncRNAs in osteoarthritis

Lei Chen, Yingqi Zhang, Zhitao Rao, Jincheng Zhang, Yeqing Sun
Pages: 1841-1849
Published online on: 27 June 2018

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Article Open Access

Identification of key pathways and biomarkers in sorafenib‑resistant hepatocellular carcinoma using bioinformatics analysis

Danping Huang, Weiqu Yuan, Hanmin Li, Shaodong Li, Zuanguang Chen, Hongzhi Yang
Pages: 1850-1858
Published online on: 09 July 2018

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Article Open Access

Efficacy and safety of febuxostat for treating hyperuricemia in patients with chronic kidney disease and in renal transplant recipients: A systematic review and meta‑analysis

Xuzhong Liu, Kun Liu, Qing Sun, Yunyan Wang, Junsong Meng, Zongyuan Xu, Zhaofei Shi
Pages: 1859-1865
Published online on: 28 June 2018

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Article Open Access

Triiodothyronine alleviates alcoholic liver disease injury through the negative regulation of the NLRP3 signaling pathway

Xiang Dong, Hongmei Yang, Cong Li, Qi Liu, Qinglin Bai, Zhaoran Zhang
Pages: 1866-1872
Published online on: 05 July 2018

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Article Open Access

A combined study of 18F‑FDG PET‑CT and fMRI for assessing resting cerebral function in patients with major depressive disorder

Chang Fu, Hongju Zhang, Ang Xuan, Yongju Gao, Junling Xu, Dapeng Shi
Pages: 1873-1881
Published online on: 09 July 2018

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Article Open Access

Efficacy and safety of mycophenolate mofetil for IgA nephropathy: An updated meta‑analysis of randomized controlled trials

Jian‑Nan Zheng, Tong‑Dan Bi, Lin‑Bo Zhu, Lin‑Lin Liu
Pages: 1882-1890
Published online on: 06 July 2018

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Article Open Access

Effect of silencing lncRNATUG1 on rapamycin‑induced inhibition of endothelial cell proliferation and migration

Xue Gao, Tao Zhang, Xi‑Yun Zeng, Guo‑Jian Li, Ling‑Juan Du, Zhen‑Huan Ma, Jia Wan, Yong Yang
Pages: 1891-1899
Published online on: 26 June 2018

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Article Open Access

Association between GDF5 single nucleotide polymorphism rs143383 and lumbar disc degeneration

Zhen Wang, Yuqian Li, Yunhao Wang, Xiaodong Wang, Jianhua Zhang, Jiwei Tian
Pages: 1900-1904
Published online on: 29 June 2018

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Article Open Access

Association of miR-182 expression in amniotic fluid with intrauterine infection and brain injury in premature infants

Fengchun Gao, Xiaojuan Jiang, Qirong Li, Kefeng Fan
Pages: 1905-1909
Published online on: 27 June 2018

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Article Open Access

Preserving hepatic artery flow during portal triad blood occlusion improves regeneration of the remnant liver in rats with obstructive jaundice following partial hepatectomy

Zhe Kong, Jian‑Jun Hu, Xin‑Lan Ge, Ke Pan, Chong‑Hui Li, Jia‑Hong Dong
Pages: 1910-1918
Published online on: 04 July 2018

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Article Open Access

Effects of imipenem combined with low‑dose cyclophosphamide on the intestinal barrier in septic rats

Peng Guo, Shun‑Wen Zhang, Jie Zhang, Jiang‑Tao Dong, Jiang‑Dong Wu, Su‑Tu Tang, Jun‑Ting Yang, Wan‑Jiang Zhang, Fang Wu
Pages: 1919-1927
Published online on: 29 June 2018

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Article Open Access

Intra‑articular, single‑shot co‑injection of hyaluronic acid and corticosteroids in knee osteoarthritis: A randomized controlled trial

Shan‑Zheng Wang, Dong‑Ying Wu, Qing Chang, Yu‑Dong Guo, Chen Wang, Wei‑Min Fan
Pages: 1928-1934
Published online on: 29 June 2018

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Article Open Access

MicroRNA‑144 mediates chronic inflammation and tumorigenesis in colorectal cancer progression via regulating C‑X‑C motif chemokine ligand 11

Bin Han, Dan Feng, Xin Yu, Yuanqi Liu, Ming Yang, Fei Luo, Liming Zhou, Fu Liu
Pages: 1935-1943
Published online on: 02 July 2018

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Article Open Access

Ultrasound‑guided continuous fascia iliaca compartment block for pre‑operative pain control in very elderly patients with hip fracture: A randomized controlled trial

Yanhui Ma, Jie Wu, Jixiu Xue, Fei Lan, Tianlong Wang
Pages: 1944-1952
Published online on: 06 July 2018

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Article Open Access

Effects of comprehensive pulmonary rehabilitation therapy on pulmonary functions and blood gas indexes of patients with severe pneumonia

Wei Liu, Xuri Mu, Xin Wang, Peipei Zhang, Li Zhao, Qiuju Li
Pages: 1953-1957
Published online on: 03 July 2018

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Article Open Access

Expression and significance of autophagy genes LC3, Beclin1 and MMP-2 in endometriosis

Xiaoyu Sui, Yadong Li, Yurong Sun, Chunyan Li, Xiulan Li, Guiyu Zhang
Pages: 1958-1962
Published online on: 27 June 2018

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Article Open Access

Reduced hepcidin level features osteoporosis

Bin Liu, Caihua Liu, Weifeng Zhong, Min Song, Shouqin Du, Jianli Su
Pages: 1963-1967
Published online on: 05 July 2018

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Article Open Access

Baicalin and puerarin reverse epithelial‑mesenchymal transition via the TGF‑β1/Smad3 pathway in vitro

Tao Wu, Tao Liu, Lianjun Xing, Guang Ji
Pages: 1968-1974
Published online on: 04 July 2018

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Article Open Access

The role of Wnt signaling pathway in atherosclerosis and its relationship with angiogenesis

Jingru Du, Junfeng Li
Pages: 1975-1981
Published online on: 03 July 2018

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Article Open Access

Correlation between the expression of inflammatory cytokines IL-6, TNF-α and hs-CRP and unfavorable fetal outcomes in patients with pregnancy-induced hypertension

Dehua Kong, Hui Wang, Yan Liu, Hongjun Li, Hongyan Wang, Peng Zhu
Pages: 1982-1986
Published online on: 02 July 2018

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Article Open Access

Nerve growth factor and substance P may be involved in moist exposed burn ointment‑mediated chronic refractory wound healing

Huang‑De Fu, Shu Wang, Bin Ge, Li‑Qing Li, Hong‑Meng Zeng, Qing‑Feng Shu, Yang Zhou
Pages: 1987-1993
Published online on: 02 July 2018

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Case Report Open Access

Hybrid surgery for an arteriovenous malformation fed by an accessory middle cerebral artery and drained by a developmental venous anomaly: A case report and literature review

Kailing Li, Yunbao Guo, Limei Qu, Baofeng Xu, Kan Xu, Jinlu Yu
Pages: 1994-2000
Published online on: 29 June 2018

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Article Open Access

H1N1 influenza virus epitopes classified by monoclonal antibodies

Chunyan Guo, Haixiang Zhang, Xin Xie, Yang Liu, Lijun Sun, Huijin Li, Pengbo Yu, Hanyu Hu, Jingying Sun, Yuan Li, Qing Feng, Xiangrong Zhao, Daoyan Liang, Zhen Wang, Jun Hu
Pages: 2001-2007
Published online on: 09 July 2018

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Article Open Access

Therapeutic effect of berberine on renal ischemia-reperfusion injury in rats and its effect on Bax and Bcl-2

Haiya Zheng, Jun Lan, Jinmei Li, Leili Lv
Pages: 2008-2012
Published online on: 04 July 2018

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Article

Effect of JAK2/STAT3 signaling pathway on liver injury associated with severe acute pancreatitis in rats

Minli Li, Xiaohua Zhang, Bin Wang, Xiaobing Xu, Xiaowei Wu, Meixia Guo, Fangyu Wang
Pages: 2013-2021
Published online on: 09 July 2018

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Article Open Access

The relationship between insulin resistance, adiponectin and C-reactive protein and vascular endothelial injury in diabetic patients with coronary heart disease

Weihua Xu, Minghui Tian, Yanju Zhou
Pages: 2022-2026
Published online on: 04 July 2018

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Case Report

Chronic pulmonary complications associated with toxic epidermal necrolysis: A case report and literature review

Nuo Xu, Xuehua Chen, Shengdi Wu, Maosong Ye, Meiling Zhang, Lin Tong, Xiaodan Zhu, Jie Liu, Feifei Hu, Chunxue Bai
Pages: 2027-2031
Published online on: 27 June 2018

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Article

The biological effect and mechanism of the Wnt/β‑catenin signaling pathway on malignant melanoma A375 cells

Yuxia Lin, Fangfei Wang, Qingfei Xing, Feng Guo, Mengzhen Wang, Yunjie Li
Pages: 2032-2037
Published online on: 06 July 2018

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Article

MicroRNA‑21 promotes the proliferation, migration and invasion of non‑small cell lung cancer A549 cells by regulating autophagy activity via AMPK/ULK1 signaling pathway

Shuping Li, Xiaofei Zeng, Ruidong Ma, Li Wang
Pages: 2038-2045
Published online on: 29 June 2018

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Article

Improved heart failure by Rhein lysinate is associated with p38MAPK pathway

Wei Wang, Xin Meng, Jing Wang, Yong Li
Pages: 2046-2051
Published online on: 09 July 2018

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Article

Impact of weight cycling on CTRP3 expression, adipose tissue inflammation and insulin sensitivity in C57BL/6J mice

Xin Li, Li Jiang, Miao Yang, Yu‑Wen Wu, Jia‑Zhong Sun
Pages: 2052-2059
Published online on: 04 July 2018

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Case Report

Hemophagocytic lymphohistiocytosis presenting with annular erythema multiforme‑like eruptions in a patient with angioimmunoblastic T cell lymphoma: A case report

Liping Zhang, Chunguang Tong, Yaqi Tan, Shiguang Peng, Yanling He, Tianyou Wang
Pages: 2060-2065
Published online on: 06 July 2018

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Article

Ultrasonic evaluation of congenital vaginal oblique septum syndrome: A study of 21 cases

Yong‑Hao Gai, Hui‑Li Fan, Ye Yan, Shi‑Feng Cai, Yue‑Zhong Zhang, Ru‑Xin Song, Shu‑Liang Song
Pages: 2066-2070
Published online on: 06 July 2018

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Article

Specific matrix metalloproteinases and calcification factors are associated with the vulnerability of human carotid plaque

Zhou‑Ying Guo, Bai Zhang, Yan‑Hong Yan, Shang‑Shang Gao, Jing‑Jing Liu, Lan Xu, Pin‑Jing Hui
Pages: 2071-2079
Published online on: 09 July 2018

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Article

Knockdown of BACE1‑AS by siRNA improves memory and learning behaviors in Alzheimer's disease animal model

Wenting Zhang, Hao Zhao, Qian Wu, Wenan Xu, Minwu Xia
Pages: 2080-2086
Published online on: 27 June 2018

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Article

Computerized tomography features and clinicopathological analysis of Kimura disease in head and neck

Li Zhang, Li Yao, Wei‑Wei Zhou, Jian‑Nan Ma, Chun‑Qian Zhang
Pages: 2087-2093
Published online on: 09 July 2018

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Article

Combination of catheter ablation for non‑valvular atrial fibrillation and left atrial appendage occlusion in a single procedure

Xuexun Li, Jianping Li, Hongxia Chu, Lihong Wang, Lei Shi, Guangqiang Wang, Xiaofei Wang
Pages: 2094-2100
Published online on: 27 June 2018

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Article

Wnt3a‑regulated TCF4/β‑catenin complex directly activates the key Hedgehog signalling genes Smo and Gli1

Youpei Wang, Peipei Lin, Qing Wang, Meiqin Zheng, Lingxia Pang
Pages: 2101-2107
Published online on: 29 June 2018

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Article Open Access

Preliminary study on the effect of brazilin on biofilms of Staphylococcus aureus

Dan Peng, Anlin Chen, Bin Shi, Xun Min, Tao Zhang, Zheling Dong, Huan Yang, Xianlian Chen, Yingbiao Tian, Zehui Chen
Pages: 2108-2118
Published online on: 04 July 2018

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Article

Clinical therapy of hyaluronic acid combined with platelet‑rich plasma for the treatment of knee osteoarthritis

Wenxing Yu, Peng Xu, Guiling Huang, Lin Liu
Pages: 2119-2125
Published online on: 06 July 2018

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Article

Inflammatory cytokine expression in patients with sepsis at an intensive care unit

Lili Wang, Hongyan Zhao, Dongxu Wang
Pages: 2126-2131
Published online on: 29 June 2018

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Article

The 4‑hydroxynonenal mediated oxidative damage of blood proteins and lipids involves secondary lipid peroxidation reactions

Ayman G. Mustafa, Mahmoud A. Alfaqih, Othman Al‑Shboul
Pages: 2132-2137
Published online on: 06 July 2018

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Article

Andrographolide attenuates viral myocarditis through interactions with the IL‑10/STAT3 and P13K/AKT/NF‑κβ signaling pathways

Yaxin Zhao, Meng Wang, Yang Li, Wanting Dong
Pages: 2138-2143
Published online on: 29 June 2018

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Article

Transanal endorectal stepwise gradient muscular cuff cutting pull‑through method: Technique refinements and comparison with laparoscopy‑assisted procedures

Zebing Zheng, Fan Zhang, Zhu Jin, Mingjuan Gao, Yuchen Mao, Yan Qu, Yuanmei Liu
Pages: 2144-2151
Published online on: 06 July 2018

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Article

Reversible splenial lesion syndrome associated with acute Mycoplasma pneumoniae‑associated encephalitis: A report of four cases and literature review

Xiaoyu Dong, Shuyan Cong
Pages: 2152-2159
Published online on: 02 July 2018

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Article

Antitumor effect of recombinant Mycobacterium smegmatis expressing MAGEA3 and SSX2 fusion proteins

Wen Jian, Xin Li, Jian Kang, Yingfeng Lei, Yinlan Bai, Ying Xue
Pages: 2160-2166
Published online on: 09 July 2018

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Correction Open Access

[Erratum] Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell‑derived endothelial cell‑like cells via upregulation of Cx37, Cx40 and Cx43

Zhe Li, Sha Zhang, Liang Cao, Wei Li, Yu‑Chen Ye, Zi‑Xuan Shi, Zong‑Ren Wang, Lian‑Xu Sun, Jia‑Wei Wang, Lin‑Tao Jia, Wen Wang
Pages: 2167-2167
Published online on: 09 July 2018

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Correction Open Access

[Corrigendum] Protective effect of astragalosides from Radix Astragali on adriamycin-induced podocyte injury

Yi‑Pa Sai, Yuan‑Chun Song, Xing‑Xing Chen, Xuan Luo, Jing Liu, Wei‑Jing Cui
Pages: 2168-2168
Published online on: 27 June 2018

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Review Open Access

Cycloastragenol: An exciting novel candidate for age‑associated diseases (Review)

Yongjie Yu, Limin Zhou, Yajun Yang, Yuyu Liu
Pages: 2175-2182
Published online on: 20 July 2018

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Review

Novel treatment strategies for patients with HER2‑positive breast cancer who do not benefit from current targeted therapy drugs (Review)

Nan Jiang, Jing‑Jing Lin, Jun Wang, Bei‑Ning Zhang, Ao Li, Zheng‑Yang Chen, Song Guo, Bin‑Bin Li, Yu‑Zhong Duan, Ru‑Yi Yan, Hong‑Feng Yan, Xiao‑Yan Fu, Jin‑Lian Zhou, He‑Ming Yang, Yan Cui
Pages: 2183-2192
Published online on: 17 July 2018

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Article Open Access

Effect of hyperbaric oxygenation therapy on post‑concussion syndrome (Review) Corrigendum in /10.3892/etm.2018.6796

Yang Dong, Xia Hua Hu, Tao Wu, Tong Wang
Pages: 2193-2202
Published online on: 18 July 2018

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Review

Applications and development of permeability imaging in ischemic stroke (Review)

Hui Chen, Guangming Zhu, Nan Liu, Ying Li, Yonghong Xia
Pages: 2203-2207
Published online on: 17 July 2018

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Article Open Access

In vitro study on human umbilical cord mesenchymal stem cells transfected with lentivirus‑mediated hNIS‑EGFP dual reporter gene and co‑labeled with superparamagnetic iron oxide

Yu Meng, Huanhuan Liu, Ning Bian, Jian Gong, Xing Zhong, Chunrong Huang, Wenxue Liang, Hao Xu
Pages: 2208-2218
Published online on: 23 July 2018

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Article Open Access

Protective effects of primary neural stem cell treatment in ischemic stroke models

Xiaowen Yu, Xiaoqing Wang, Shuxiong Zeng, Xiping Tuo
Pages: 2219-2228
Published online on: 18 July 2018

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Article Open Access

Morroniside protects against cerebral ischemia/reperfusion injury by inhibiting neuron apoptosis and MMP2/9 expression

Guoyong Zeng, Weijiang Ding, Yin Li, Meiying Sun, Liying Deng
Pages: 2229-2234
Published online on: 17 July 2018

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Article Open Access

Long noncoding RNA EZR‑AS1 promotes tumor growth and metastasis by modulating Wnt/β‑catenin pathway in breast cancer

Yu Bai, Xian Zhou, Luo Huang, Yue Wan, Xiaoyu Li, Ying Wang
Pages: 2235-2242
Published online on: 18 July 2018

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Article Open Access

Long non‑coding RNA NEAT1 promotes migration and invasion of oral squamous cell carcinoma cells by sponging microRNA‑365

Xiaohua Liu, Wenzhi Shang, Fuju Zheng
Pages: 2243-2250
Published online on: 20 July 2018

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Article Open Access

Free bladder mucosa graft harvested by water‑jet: A novel, minimally invasive technique for urethral reconstruction

Zhixian Wang, Xiaoyong Zeng, Ruibao Chen, Tao Wang, Jia Hu, Shaogang Wang, Jihong Liu
Pages: 2251-2256
Published online on: 18 July 2018

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Article Open Access

Thromboelastography‑derived parameters for the prediction of acute thromboembolism following non‑steroidal anti‑inflammatory drug‑induced gastrointestinal bleeding: A retrospective study

Tian‑Yu Chi, Ying Liu, Hong‑Ming Zhu, Mei Zhang
Pages: 2257-2266
Published online on: 18 July 2018

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Article Open Access

Hes1 negatively regulates neurogenesis in the adult mouse dentate gyrus following traumatic brain injury

Rong Yan, Lin Zhang, Mengqi Li, Xiaozhi Liu, Xinyu Yang, Lei Chen
Pages: 2267-2274
Published online on: 17 July 2018

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Article Open Access

Triptolide protects podocytes via autophagy in immunoglobulin A nephropathy

Shikai Liang, Juan Jin, Xiaogang Shen, Xinxin Jiang, Yiwen Li, Qiang He
Pages: 2275-2280
Published online on: 19 July 2018

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Article Open Access

Exome sequencing reveals a novel MFN2 missense mutation in a Chinese family with Charcot‑Marie‑Tooth type 2A

Yi You, Xiaodong Wang, Shan Li, Xiuli Zhao, Xue Zhang
Pages: 2281-2286
Published online on: 24 July 2018

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Article Open Access

Osteogenic potential of cell spheroids composed of varying ratios of gingiva‑derived and bone marrow stem cells using concave microwells

Jae‑Yong Tae, Hyuna Lee, Hyunjin Lee, Youngkyung Ko, Jun‑Beom Park
Pages: 2287-2294
Published online on: 18 July 2018

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Article Open Access

Research on the changes in balance motion behavior and learning, as well as memory abilities of rats with multiple cerebral concussion-induced chronic traumatic encephalopathy and the underlying mechanism

Huan Zhang, Zhenguang Zhang, Zhen Wang, Yongjiang Zhen, Jiangyun Yu, Hai Song
Pages: 2295-2302
Published online on: 18 July 2018

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Article Open Access

Effects of glutamine on cytokines 1L‑1 and TNF‑α in rehabilitation and prognosis of patients with lobectomy

Xuefeng Wang, Lei Huang, Yanxia Qu, Hongmei Lv, Xiaohua He
Pages: 2303-2308
Published online on: 13 July 2018

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Article Open Access

Effects of UV on apoptotic factors in lens epithelial cells of an animal model

Juling Lv, Yiqiao Xing
Pages: 2309-2312
Published online on: 10 July 2018

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Article Open Access

Impact of G-CSF on expressions of Egr-1 and VEGF in acute ischemic cerebral injury

Dian-Gui Zhou, Yang-Hong Shi, You-Qiang Cui
Pages: 2313-2318
Published online on: 19 July 2018

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Article Open Access

Mesalazine suppository for the treatment of refractory ulcerative chronic radiation proctitis

Changliang Wu, Liyu Guan, Li Yao, Jiean Huang
Pages: 2319-2324
Published online on: 18 July 2018

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Article Open Access

Correlation analysis of intestinal flora with hypertension

Jilun Liu, Ning An, Cong Ma, Xiaofeng Li, Jie Zhang, Wei Zhu, Yihe Zhang, Junpeng Li
Pages: 2325-2330
Published online on: 20 July 2018

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Article Open Access

Percutaneous renal artery stent implantation in the treatment of atherosclerotic renal artery stenosis

Youbin Hu, Yongguang Zhang, Hua Wang, Yong Yin, Chunhua Cao, Jing Luo, Yunfei Wang
Pages: 2331-2336
Published online on: 13 July 2018

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Article

LncRNA MEG3 overexpression inhibits the development of diabetic retinopathy by regulating TGF‑β1 and VEGF

Daning Zhang, Haixiang Qin, Ying Leng, Xiangjun Li, Lei Zhang, Dan Bai, Yujun Meng, Jingyi Wang
Pages: 2337-2342
Published online on: 17 July 2018

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Article Open Access

Imaging manifestations of B-mode ultrasound combined with CT in tuberculous pleuritis patients and the diagnostic value

Shisheng Zhou, Jiming Zhao, Xianhui Song, Mei Zheng, Hong Li, Yinghua Pan
Pages: 2343-2348
Published online on: 18 July 2018

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Article Open Access

Cilostazol on the expression of ICAM‑1, VCAM-1and inflammatory factors in plasma in patients with thromboangiitis obliterans

Fuchen Song, Bo Ji, Ting Chen
Pages: 2349-2354
Published online on: 11 July 2018

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Article Open Access

Immunomagnetic enrichment to evaluate the role of home environment specimens in transmission of enterovirus 71

Wangfeng Zhu, Xiuhui Yang, Yong Zhou, Yansheng Yan
Pages: 2355-2362
Published online on: 19 July 2018

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Article Open Access

Salidroside prevents hydroperoxide‑induced oxidative stress and apoptosis in retinal pigment epithelium cells

Yan Yin, Dejie Liu, Donghua Tian
Pages: 2363-2368
Published online on: 20 July 2018

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Article Open Access

Pharmaceutical analysis of different antibiotic regimens in the treatment of lower respiratory tract infection

Lin Zhang, Benhong Liu, Chunbin Wang
Pages: 2369-2374
Published online on: 11 July 2018

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Article Open Access

Effect of intraperitoneal or intracerebroventricular injection of streptozotocin on learning and memory in mice

Yang Zhang, Rong Ding, Shanshan Wang, Zhiyun Ren, Lingyan Xu, Xunle Zhang, Jiahui Zhao, Yu Ding, Yu Wu, Yuesong Gong
Pages: 2375-2380
Published online on: 19 July 2018

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Article Open Access

Effect of montelukast on the expression of CD4+CD25+ regulatory T cells in children with acute bronchial asthma

Xiaoting Qu, Yuan Chen, Chaoyang Yin
Pages: 2381-2386
Published online on: 19 July 2018

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Article Open Access

Immunohistochemical profile of long‑standing traumatic retinal detachment in atrophic globe in a young patient

Shiliang Liu, Yuanyuan Chen, Zhen Chen, Yiqiao Xing, Yin Shen
Pages: 2387-2391
Published online on: 20 July 2018

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Article Open Access

Hypermethylation of the κ1 opioid receptor promoter in Chinese heroin and methamphetamine addicts

Huihui Ji, Guili Liu, Xuting Xu, Huifen Liu, Lei Xu, Haochang Hu, Yingmin Chen, Qinxiao Hong, Qinwen Wang, Wenwen Shen, Longhui Li, Xiaohu Xie, Wenhua Zhou, Shiwei Duan
Pages: 2392-2398
Published online on: 24 July 2018

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Article Open Access

In vitro culture and biological properties of broiler adipose‑derived stem cells

Tengfei Lu, Wenhua Pei, Kunfu Wang, Shuang Zhang, Fenghao Chen, Yangnan Wu, Weijun Guan
Pages: 2399-2407
Published online on: 16 July 2018

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Article Open Access

Vascularization of vessel pedicle in hypospadias and its relationship to near‑period complications

Zhang Zhao, Ning Sun, Xiangming Mao
Pages: 2408-2412
Published online on: 18 July 2018

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Article Open Access

Arthroscopic partial capsulotomy for exposure and treatment of hip disease

Ze Zhuang, Yuxian Chen, Kishor Chhantyal, Ronghan He, Tangzhao Liang, Dehai Shi
Pages: 2413-2419
Published online on: 17 July 2018

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Article Open Access

Serum exosomal miR‑328, miR‑575, miR‑134 and miR‑671‑5p as potential biomarkers for the diagnosis of Kawasaki disease and the prediction of therapeutic outcomes of intravenous immunoglobulin therapy

Xiaofei Zhang, Guangda Xin, Dajun Sun
Pages: 2420-2432
Published online on: 17 July 2018

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Article Open Access

miRNA‑218 regulates the proliferation and apoptosis of cervical cancer cells via targeting Gli3

Jing Zhang, Shengze Li, Yanhua Li, Hongli Liu, Yuan Zhang, Qingsong Zhang
Pages: 2433-2441
Published online on: 20 July 2018

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Article Open Access

Quercetin is able to alleviate TGF‑β‑induced fibrosis in renal tubular epithelial cells by suppressing miR‑21

Yaochen Cao, Jialin Hu, Jianying Sui, Limei Jiang, Yakun Cong, Guoqing Ren
Pages: 2442-2448
Published online on: 20 July 2018

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Article Open Access

Efficacy and safety of baricitinib for active rheumatoid arthritis in patients with an inadequate response to conventional synthetic or biological disease‑modifying anti‑rheumatic drugs: A meta‑analysis of randomized controlled trials

Zhi‑Peng Wu, Pei Zhang, Jian‑Zhong Bai, Yuan Liang, Jin‑Shan He, Jing‑Cheng Wang
Pages: 2449-2459
Published online on: 20 July 2018

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Article Open Access

Screening of genes associated with inflammatory responses in the endolymphatic sac reveals underlying mechanisms for autoimmune inner ear diseases

Juhong Zhang, Na Wang, Anting Xu
Pages: 2460-2470
Published online on: 19 July 2018

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Article Open Access

Altered circulating T follicular helper cells in patients with chronic immune thrombocytopenia

Lan Dai, Linyan He, Zhaoyue Wang, Xia Bai, Yang He, Lijuan Cao, Mingqing Zhu, Changgeng Ruan
Pages: 2471-2477
Published online on: 23 July 2018

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Article Open Access

Values of detection of NF-κB activation level combined with IL-6 and TNF-α levels in peripheral neutrophils in the prediction of multiple organ dysfunction syndrome in patients with severe multiple trauma

Jie Zeng
Pages: 2478-2482
Published online on: 18 July 2018

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Article Open Access

Mitochondrial damage in hippocampal neurons of rats with epileptic protein expression of Fas and caspase-3

Junqiang Feng, Lifang Feng, Guiru Zhang
Pages: 2483-2489
Published online on: 13 July 2018

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Article Open Access

Modified Huangqi Chifeng decoction inhibits excessive autophagy to protect against Doxorubicin‑induced nephrotic syndrome in rats via the PI3K/mTOR signaling pathway

Zi‑Kai Yu, Bin Yang, Yu Zhang, Liu‑Sheng Li, Jin‑Ning Zhao, Wei Hao
Pages: 2490-2498
Published online on: 20 July 2018

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Article Open Access

Berberine inhibits cardiac remodeling of heart failure after myocardial infarction by reducing myocardial cell apoptosis in rats

Ying Liao, Kaihong Chen, Xingmo Dong, Weiguo Li, Ganyang Li, Guoyong Huang, Wei Song, Liling Chen, Yong Fang
Pages: 2499-2505
Published online on: 11 July 2018

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Article Open Access

Effect of ranibizumab on levels of IL-6 and VEGF in peripheral blood and aqueous humor of glaucoma rat model and association of IL-6 and VEGF with optic nerve damage

Yanling Song, Qiujie Song, Ling Li, Jinfeng Xu, Xingqiang Liu
Pages: 2506-2510
Published online on: 13 July 2018

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Article Open Access

Automated nasopharyngeal carcinoma segmentation in magnetic resonance images by combination of convolutional neural networks and graph cut

Zongqing Ma, Xi Wu, Qi Song, Yong Luo, Yan Wang, Jiliu Zhou
Pages: 2511-2521
Published online on: 18 July 2018

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Article Open Access

Effects of SB202190 on expression levels of IL-6 and NF-κB in flap ischemia-reperfusion injury

Kai Guo, Jingxin Ma, Wenyong Liang
Pages: 2522-2526
Published online on: 13 July 2018

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Case Report Open Access

Clinical significance of circulating tumor cells via combined whole exome sequencing in early stage cancer screening: A case report

Zijian Su, Jiangman Zhao, Shaoying Ke, Jian Zhang, Xiaoyu Liu, Yu Wang, Qihong Sun, Qunxiong Pan
Pages: 2527-2533
Published online on: 23 July 2018

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Article Open Access

Bioinformatics identification of potential candidate blood indicators for doxorubicin‑induced heart failure

Guo‑Xing Wan, Li‑Hua Ji, Wen‑Bin Xia, Lan Cheng, Yong‑Gang Zhang
Pages: 2534-2544
Published online on: 19 July 2018

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Article Open Access

Meta‑analysis of the benefit of sitagliptin treatment in patients with type 2 diabetes complicated with incipient nephropathy

Wei Liu, Jiangyi Yu, Qianhua Yan, Lijuan Wang, Nan Li, Wei Xiong
Pages: 2545-2553
Published online on: 17 July 2018

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Case Report Open Access

Pulmonary actinomycosis diagnosed by transbronchoscopic lung biopsy: A case report and literature review

Xing Ding, Gengyun Sun, Guanghe Fei, Xuexin Zhou, Luqian Zhou, Ran Wang
Pages: 2554-2558
Published online on: 19 July 2018

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Article Open Access

Effect of saxagliptin on the expression of HIF‑1α in the liver of diabetic rats with fatty liver

Qian Zhao, Qian Xiao, Xiangying Meng, Jianyang Chen, Weiwei Ye, Yong Zhou
Pages: 2559-2563
Published online on: 18 July 2018

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Article Open Access

Flos Chrysanthemi Indici extract improves a high‑sucrose diet‑induced metabolic disorder in Drosophila

Ye Bai, Kun Li, Jiayao Shao, Qiuxiang Luo, Li Hua Jin
Pages: 2564-2572
Published online on: 18 July 2018

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Article Open Access

Effects of hepatic blood inflow on liver ultrastructure and regeneration after extensive liver resection in rats with cirrhosis

Wang‑Xun Jin, Bing Wang, Yun‑Li Zhang, Ruizeng Dong, Xin‑Bao Wang, Jian‑Min Guo, Sunfu Fan , Bingqi Yu
Pages: 2573-2583
Published online on: 18 July 2018

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Article Open Access

Analyzing the disease module associated with osteosarcoma via a network‑ and pathway‑based approach

Yi Zhang, Fei Yang
Pages: 2584-2592
Published online on: 23 July 2018

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Article

Luteolin decreases atherosclerosis in LDL receptor‑deficient mice via a mechanism including decreasing AMPK‑SIRT1 signaling in macrophages

Jiang Li, Jian‑Zeng Dong, Yan‑Long Ren, Jia‑Jia Zhu, Jia‑Ning Cao, Jing Zhang, Li‑Li Pan
Pages: 2593-2599
Published online on: 20 July 2018

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Article

Effects of salvianolic acid on cerebral perfusion in patients after acute stroke: A single‑center randomized controlled trial

Jian‑Wei Peng, Yuan Liu, Gai Meng, Jin‑Yan Zhang, Lian‑Fang Yu
Pages: 2600-2614
Published online on: 16 July 2018

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Article

Tumor suppressor function of miR‑483‑3p on breast cancer via targeting of the cyclin E1 gene

Xiaoxi Huang, Jin Lyu
Pages: 2615-2620
Published online on: 23 July 2018

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Article

Quantification of nitric oxide by high‑performance liquid chromatography‑fluorometric method in subgenomic hepatitis C virus‑replicon expressing Huh7 cells upon treatment with acetylsalicylic acid

Clara Patricia Rios‑Ibarra, Victor Torres‑De La Cruz, Andrea Gabriela Ochoa‑Ruiz, Ana María Rivas‑Estilla
Pages: 2621-2626
Published online on: 24 July 2018

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Article

Magnetic wires: A novel design for neuroendovascular coil retrieval

Lingyun Zhang, Yugang Jiang
Pages: 2627-2632
Published online on: 23 July 2018

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Article

Neuroprotective effect of recombinant adeno‑associated virus human thioredoxin‑PR39 on acute cerebral infarction in rats

Yu‑Dong Guo, Teng Huang, Wen‑Hua Sheng, Yun‑Fei Guan, Yi‑Feng Du, You‑Ting Lin, Xi‑Yun Ruan
Pages: 2633-2638
Published online on: 17 July 2018

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Case Report

Complement 3 glomerulonephritis in rheumatoid arthritis: A case report and follow‑up

Xin Wang, Lu Han, Huifang Li, Dongmei Zhang
Pages: 2639-2644
Published online on: 18 July 2018

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Article

Identification of a novel TCOF1 mutation in a Chinese family with Treacher Collins syndrome

Zhiqiang Yan, Yu Lu, Yanfei Wang, Xiuju Zhang, Hong Duan, Jing Cheng, Huijun Yuan, Dongyi Han
Pages: 2645-2650
Published online on: 16 July 2018

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Article

Activation of EphA4 induced by EphrinA1 exacerbates disruption of the blood‑brain barrier following cerebral ischemia‑reperfusion via the Rho/ROCK signaling pathway

Fangbin Chen, Zhiyang Liu, Wei Peng, Zhiqin Gao, Hui Ouyang, Tongjun Yan, Songbai Ding, Zhankui Cai, Bin Zhao, Longjin Mao, Zhiyong Cao
Pages: 2651-2658
Published online on: 17 July 2018

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Article

Association of cytokine gene polymorphisms with osteoarthritis susceptibility

Otilia Constantina Rogoveanu, Daniela Calina, Mihai Gabriel Cucu, Florin Burada, Anca Oana Docea, Simona Sosoi, Emilian Stefan, Mihai Ioana, Emilia Burada
Pages: 2659-2664
Published online on: 18 July 2018

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Article

miR‑148a inhibits pro‑inflammatory cytokines released by intervertebral disc cells by regulating the p38/MAPK pathway

Guangfeng Li, Xianye Tang, Hongliang Chen, Wei Sun, Feng Yuan
Pages: 2665-2669
Published online on: 24 July 2018

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Article

Tetrandrine alleviates symptoms of rheumatoid arthritis in rats by regulating the expression of cyclooxygenase‑2 and inflammatory factors

Xiang Li, Zhongxiu Wu, Bin He, Wei Zhong
Pages: 2670-2676
Published online on: 20 July 2018

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Case Report

Recurrent cerebellar infarction associated with hereditary heterozygous protein C deficiency in a 35‑year‑old woman: A case report and genetic study on the pedigree

Pingping Li, Chao Qin
Pages: 2677-2681
Published online on: 25 July 2018

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Article

Biomechanical bearing‑based typing method for osteonecrosis of the femoral head: ABC typing

Zhennan Zhang, Tong Yu, Limin Xie, Yubin Li, Xun Ke, Yang Liu, Songmin Huang, Hao Deng, Yang Bai
Pages: 2682-2688
Published online on: 20 July 2018

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Article

Acetylpuerarin inhibits oxygen‑glucose deprivation‑induced neuroinflammation of rat primary astrocytes via the suppression of HIF‑1 signaling

Yanxiao Xiang, Pengchao Du, Xiumei Zhang, Siddhartha Biswas, Guangjun Jiao, Haichun Liu
Pages: 2689-2695
Published online on: 23 July 2018

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Article

Overexpression of microRNA‑936 suppresses non‑small cell lung cancer cell proliferation and invasion via targeting E2F2

Xiao Zhou, Hui Tao
Pages: 2696-2702
Published online on: 20 July 2018

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Article

Overexpression of CD64 on CD14++CD16‑ and CD14++CD16+ monocytes of rheumatoid arthritis patients correlates with disease activity

Qing Luo, Pengcheng Xiao, Xue Li, Zhen Deng, Cheng Qing, Rigu Su, Jianqing Xu, Yang Guo, Zikun Huang, Junming Li
Pages: 2703-2711
Published online on: 17 July 2018

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Case Report

Acute bilateral vision deficit as the initial symptom in Guillain‑Barre syndrome: A case report

Hui‑Jun Wen
Pages: 2712-2716
Published online on: 18 July 2018

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Article

miR‑192 is upregulated in T1DM, regulates pancreatic β‑cell development and inhibits insulin secretion through suppressing GLP‑1 expression

Wen Pan, Yanan Zhang, Chun Zeng, Fen Xu, Jinhua Yan, Jianping Weng
Pages: 2717-2724
Published online on: 17 July 2018

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Article

Adiponectin is valuable in the diagnosis of acute heart failure with renal insufficiency

Zhang Dai, Yan Zhang, Huiming Ye, Guoqiang Zhang, Hongwei Jin, Ziming Chen, Yihui Yao, Xuebing Tian, Jianfeng Zhou, Peihua Li, Xianming Liang, Huabing Xie, Shengxiang Ge, Zhongying Zhang
Pages: 2725-2734
Published online on: 23 July 2018

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Article

Phosphatidylinositol 3‑kinase‑mediated HO‑1/CO represses Fis1 levels and alleviates lipopolysaccharide‑induced oxidative injury in alveolar macrophages

Jia Shi, Jianbo Yu, Yuan Zhang, Zhen Li, Lirong Gong, Shuan Dong, Rui Mu
Pages: 2735-2742
Published online on: 17 July 2018

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Article

Efficacy and tolerability of interferon‑free regimen for patients with genotype‑1 HCV infection

Kosuke Takeda, Ryuichi Noguchi, Tadashi Namisaki, Kei Moriya, Takemi Akahane, Mitsuteru Kitade, Hideto Kawaratani, Naotaka Shimozato, Kosuke Kaji, Hiroaki Takaya, Yasuhiko Sawada, Kenichiro Seki, Yukihisa Fujinaga, Yuki Tsuji, Takuya Kubo, Shinya Sato, Soichiro Saikawa, Keisuke Nakanishi, Masanori Furukawa, Koh Kitagawa, Takahiro Ozutsumi, Daisuke Kaya, Akira Mitoro, Tsuyoshi Mashitani, Yasushi Okura, Junichi Yamao, Hitoshi Yoshiji
Pages: 2743-2750
Published online on: 19 July 2018

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Article

Verteporfin enhances the sensitivity of LOVO/TAX cells to taxol via YAP inhibition

Ganggang Shi, Hao Wang, Hongqiu Han, Jianchen Gan, Hui Wang
Pages: 2751-2755
Published online on: 16 July 2018

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Article

Icariin prevents cytokine‑induced β‑cell death by inhibiting NF‑κB signaling

Shao Zhong, Jing Ge, Jiang‑Yi Yu
Pages: 2756-2762
Published online on: 20 July 2018

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Article

MicroRNA‑126 accelerates IgE‑mediated mast cell degranulation associated with the PI3K/Akt signaling pathway by promoting Ca2+ influx

Yuan Bao, Song Wang, Yang Gao, Wen Zhang, Haitao Jin, Yang Yang, Jiangyu Li
Pages: 2763-2769
Published online on: 23 July 2018

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Article

Tuberculous meningitis diagnosis and treatment in adults: A series of 189 suspected cases

Mengchuan Luo, Weifei Wang, Qiuming Zeng, Yuebei Luo, Huan Yang, Xiaosu Yang
Pages: 2770-2776
Published online on: 20 July 2018

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Editorial Open Access

[Editorial] Does Europe need paediatric virologists?

Ioannis N. Mammas, Anne Greenough, Maria Theodoridou, Demetrios A. Spandidos
Pages: 2783-2784
Published online on: 31 July 2018

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Article Open Access

Evaluating the proposal of paediatric virology: An interview with Professor Tina Dalianis, Professor of Tumour Virology at Karolinska Institutet

Ioannis N. Mammas, Demetrios A. Spandidos
Pages: 2785-2789
Published online on: 31 July 2018

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Article Open Access

Neonatology, paediatrics and paediatric virology on a British island: An interview with neonatologist Dr Prakash Thiagarajan (Isle of Man)

Ioannis N. Mammas, Demetrios A. Spandidos
Pages: 2790-2794
Published online on: 31 July 2018

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Article Open Access

Paediatric virology as a candidate of paediatric subspecialisation: An interview with Assistant Professor of Molecular Microbiology-Virology Angeliki Melidou

Ioannis N. Mammas, Demetrios A. Spandidos
Pages: 2795-2798
Published online on: 31 July 2018

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Article Open Access

The philosophy of paediatric teaching: An interview with Dr Nikolaos Myriokefalitakis, former Clinical Director of the ‘Penteli’ Children's Hospital in Athens (Greece)

Ioannis N. Mammas, Demetrios A. Spandidos
Pages: 2799-2802
Published online on: 31 July 2018

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Editorial Open Access

[Editorial] The future of paediatric education

Ioannis N. Mammas, Demetrios A. Spandidos, Alan Michael Weindling
Pages: 2803-2804
Published online on: 31 July 2018

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Article Open Access

The future of medical education in neonatology, paediatrics and paediatric virology: An interview with Professor Alan Michael Weindling, Professor of Perinatal Medicine at the University of Liverpool

Ioannis N. Mammas, Demetrios A. Spandidos
Pages: 2805-2808
Published online on: 31 July 2018

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Journal Cover
January-2026 Volume 31 Issue 1

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Impact Factor: 2.3

Article Open Access

Adiposity indices and bone health amongst Malaysian adults: Evidence from a cross‑sectional study

Wenjian Zhao, Weizheng Zhang, Kok-Yong Chin, Xiaodong Ma, Hashwin Singh Tejpal Singh, Sophia Ogechi Ekeuku, Yuanzhong Wang, Xia Ji, Yang Guo, Sok Kuan Wong, Norliza Muhammad, Teh Rohaila Jamil, Saharuddin Ahmad
Article Number: 28
Published online on: 21 November 2025

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Article Open Access

Ginsenoside Re attenuates homocysteine‑induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling

Shaolin Li, Chenge Zhao, Shengqin Yu, Kaijing Yang, Shuying Zhang, Sixu Liu
Article Number: 27
Published online on: 21 November 2025

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Case Report Open Access

Intussusception of the initial jejunum secondary to adenoma in the third and fourth portions of the duodenum: A case report

Lingbo Huo, Lixing Ma
Article Number: 26
Published online on: 21 November 2025

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Correction Open Access

[Corrigendum] Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β‑catenin signaling pathway

Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
Article Number: 25
Published online on: 19 November 2025

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Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

Shengbin Han, Jingzhe Xu, Chenchen Yu, Hongxi Guan, Shun Ding
Article Number: 24
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 23
Published online on: 17 November 2025

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Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

Jinqi Yan, Xiaohu Wang, Chen Liang
Article Number: 22
Published online on: 14 November 2025

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Review Open Access

Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

Mingxin He, Feng Chen, Xiaomin Xian, Zhi Guo
Article Number: 21
Published online on: 14 November 2025

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Article Open Access

Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

Yunching Lai, Xiaolei Chen, Hebing Zhou
Article Number: 20
Published online on: 10 November 2025

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Case Report Open Access

Diagnostic challenge of aneurysmal dermatofibroma mimicking cutaneous metastasis in a patient with lung cancer: A case report

Jong Yun Choi, Heeyang Park, Jangyoun Choi
Article Number: 19
Published online on: 10 November 2025

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Retraction Open Access

[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Article Number: 18
Published online on: 10 November 2025

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Article

Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study

Jeng-Yuan Yao, De-Tian-Yu Tzeng, Cai-Hong Feng, Gong-Man Xiao, Tian-Ni You, Ru-Yu Zheng
Article Number: 17
Published online on: 06 November 2025

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Case Report Open Access

Chronic maxillary sinusitis masquerading as a maxillary sinus neoplasm: A case report

Ji-Hyeon Oh, Seong-Gon Kim, Su-Young Kim
Article Number: 16
Published online on: 04 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
Article Number: 15
Published online on: 04 November 2025

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Article Open Access

A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

Jingqiao Li, Yipeng Yang, Xu Zhang, Dandan Zhang, Yadong Yu, Rong Chen, Wei Du
Article Number: 14
Published online on: 30 October 2025

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Case Report Open Access

Primary epithelioid angiomatous nodule of the vocal cord: A case report and literature review

Keda Li, Bin Huang, Lubing Cai, Mingqi Huang, Jianping Shi, Mingdi Jin, Ning Qian, Yongkang Guo
Article Number: 13
Published online on: 29 October 2025

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Case Report Open Access

Hepatic perivascular epithelioid cell tumor: A rare mesenchymal tumor with epithelioid features: A case report

Mahmoud Abbas, Benjamin Strücker, Mehmet Haluk Morgül, Andreas Pascher, Wolfgang Hartmann, Eva Wardelmann
Article Number: 12
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet

Lei Huang, Chao Ding, Xinmin Si
Article Number: 11
Published online on: 29 October 2025

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Article

Evaluation of total oxidant status/total antioxidant capacity and DNA damage in neonates with high lactate levels in umbilical cord blood gases

Burcu Cebeci, Aydemir Yalvaç, Derya Büyükkayhan, Dilek Kurnaz, Hakan Çakir, Murat Elevli
Article Number: 10
Published online on: 29 October 2025

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Case Report

Treatment of a mandibular molar with primary failure of eruption: A case report

Ming Guo, Weisheng Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

Effect of the water‑soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells

Xinghuanyu Xu, Lin Liu, Wenbai Zhang, Pu Xu
Article Number: 8
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Article Open Access

Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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Retraction Open Access

[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

Xiao Ma, Jingjing Ma, Han Zhang, Xiaodong Jia, Tianrui Wang, Shanshan Ma, Yingze Zhang
Article Number: 4
Published online on: 21 October 2025

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Article Open Access

Epimedin C: A promising neuroprotective agent that can participate in mediating the JNK/Nrf2/HO‑1 signaling pathway to prevent neurodegenerative diseases

Chao Cong, Xuan-Ling Li, Guang-Yao Lin, Lian-Wei Xu
Article Number: 3
Published online on: 21 October 2025

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Article Open Access

Application of pleural effusion cell blocks for immunohistochemistry and EGFR gene mutation testing for advanced lung cancer

Shouxiang Zhao, Yuhong Liu, Tao Wang, Ying Li, Ze Chen, Xiaoshan Cai
Article Number: 2
Published online on: 21 October 2025

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Correction Open Access

[Corrigendum] Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility in vitro

Huan Wang, Tingtao Chen, Yidan Chen, Tao Luo, Buzhen Tan, Houyang Chen, Hongbo Xin
Article Number: 1
Published online on: 16 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Impact Factor: 2.3

Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Case Report

Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Article Open Access

Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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Case Report

A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Article Open Access

Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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Article Open Access

The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Article Open Access

Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Article Open Access

Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Article Open Access

Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Article Open Access

Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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