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Article

Computerized tomography features and clinicopathological analysis of Kimura disease in head and neck

  • Authors:
    • Li Zhang
    • Li Yao
    • Wei‑Wei Zhou
    • Jian‑Nan Ma
    • Chun‑Qian Zhang
  • View Affiliations / Copyright

    Affiliations: Department of CT Diagnosis, Cangzhou Central Hospital, Cangzhou, Hebei 061001, P.R. China, Department of Cardiology, Cangzhou Central Hospital, Cangzhou, Hebei 061001, P.R. China, Department of Pathology, Cangzhou Central Hospital, Cangzhou, Hebei 061001, P.R. China
  • Pages: 2087-2093
    |
    Published online on: July 9, 2018
       https://doi.org/10.3892/etm.2018.6431
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Abstract

The aim of the current study was to discuss and analyze computerized tomography (CT) features and clinicopathological characteristics of patients with Kimura disease in head and neck. CT and clinicopathological data of 12 patients with Kimura disease diagnosed between May 2011 and May 2015 were analyzed. The mean age was 43.9 years and the disease course varied from 1 week‑20 years. The mean absolute value of eosinophil granulocytes was 1.95x109/l. Multiple nodules were detected in 4 patients with Kimura disease. Main symptoms included multiple enlarged lymph nodes in neck and submaxillary regions. CT imaging of nodular lesions revealed a clear boundary, with moderate to marked homogeneous enhancement. Diffuse mass lesions were observed in 6 patients with Kimura disease. Main symptoms included subcutaneous diffuse soft tissue mass in parotid gland and maxillofacial regions. CT imaging of diffuse mass revealed unclear boundaries, adjacent skin thickness and moderate heterogeneous enhancement. In some cases, the diffuse mass involved soft mass with unclear boundaries. Pathological symptoms of Kimura disease included infiltration of eosinophilia, lymphocytic proliferation, formation of lymphatic follicles and variable degrees of fibrosis and vascular proliferation. Diagnosis of Kimura disease in head and neck regions may be improved based on lesions with clear or unclear boundaries, homogeneous or heterogeneous enhancement, with or without lymphadenectasis and by the presence of peripheral blood eosinophilia. However, a final diagnosis relies on a pathological examination.
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1 

Gao Y, Chen Y and Yu GY: Clinicopathologic study of parotid involvement in 21 cases of eosinophilic hyperplastic lymphogranuloma (Kimura's disease). Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 102:651–658. 2006. View Article : Google Scholar : PubMed/NCBI

2 

Lanjewar DN, Bhosale A and Iyer A: Spectrum of dermatopathologic lesions associated with HIV/AIDS in India. Indian J Pathol Microbiol. 45:293–298. 1996.

3 

de Castro HA Jr, Lasmar MT, de Souza EA, Figueiredo JA, Nogueira BD and Tardelli FC: Renal epitelial neoplasia associated with Kimura disease. Arch Esp Urol. 63:547–549. 2010.(In English, Spanish). PubMed/NCBI

4 

Nonaka M, Sakitani E, Ono E, Yamamura Y, Seo Y, Shibata N, Pawankar R and Yoshihara T: Basophils are increased and express increased levels of interleukin-4 in the parotid lesions of kimura disease. Asia Pac Allergy. 7:221–226. 2017. View Article : Google Scholar : PubMed/NCBI

5 

Nonaka M, Sakitani E and Yoshihara T: Anti-IgE therapy to Kimura's disease: A pilot study. Auris Nasus Larynx. 41:384–388. 2014. View Article : Google Scholar : PubMed/NCBI

6 

Gopinathan A and Tan TY: Kimura's disease: Imaging patterns on computed tomography. Clin Radiol. 64:994–999. 2009. View Article : Google Scholar : PubMed/NCBI

7 

Jiang Y, Hua Q, Ren J, Zeng F, Sheng J, Liao H, Zhang Z and Guan H: Eosinophilic hyperplastic lymphogranuloma: Clinical diagnosis and treatment experience of 41 cases. Am J Otolaryngol. 38:626–629. 2017. View Article : Google Scholar : PubMed/NCBI

8 

Matsuo T, Tanaka T and Kinomura M: Nephrotic syndrome during the tapering of oral steroids after pathological diagnosis of Kimura disease from a lacrimal gland mass: Case report and review of 10 Japanese patients. J Clin Exp Hematop. 57:147–152. 2017. View Article : Google Scholar : PubMed/NCBI

9 

Zhang R, Ban XH, Mo YX, Lv MM, Duan XH, Shen J, Li JP, Liu XW and Xie CM: Kimura's disease: The CT and MRI characteristics in fifteen cases. Eur J Radiol. 80:489–497. 2011. View Article : Google Scholar : PubMed/NCBI

10 

Lin YY, Jung SM, Ko SF, Toh CH, Wong AM, Chen YR, Chan SC, Cheung YC and Ng SH: Kimura's disease: Clinical and imaging parameters for the prediction of disease recurrence. Clin Imaging. 36:272–278. 2012. View Article : Google Scholar : PubMed/NCBI

11 

Wang DY, Mao JH, Zhang Y, Gu WZ, Zhao SA, Chen YF and Liu AM: Kimura disease: A case report and review of the chinese literature. Nephron Clin Pract. 111:c55–c61. 2009. View Article : Google Scholar : PubMed/NCBI

12 

Chen C, Chen K, Huang X, Wang K and Qian S: Concurrent eosinophilia and IgG4-related disease in a child: A case report and review of the literature. Exp Ther Med. 15:2739–2748. 2018.PubMed/NCBI

13 

Iguchi Y, Inoue T, Shimono M, Yamamura T, Shigematsu T and Takahashi S: Kimura's disease and its relation to angiolymphoid hyperplasia with eosinophilia: Report of three cases and review of the literature. J Oral Pathol. 15:132–137. 1986. View Article : Google Scholar : PubMed/NCBI

14 

Arshad AR: Kimura's disease of parotid gland presenting as solitary parotid swelling. Head Neck. 25:754–757. 2003. View Article : Google Scholar : PubMed/NCBI

15 

Sawaimul K, Iqbal B and Kambale T: Kimura's disease embedding radial artery: A very rare presentation. J Cancer Res Ther. 11:10312015. View Article : Google Scholar : PubMed/NCBI

16 

Ye P, Wei T, Yu GY, Wu LL and Peng X: Comparison of local recurrence rate of three treatment modalities for kimura disease. J Craniofac Surg. 27:170–174. 2016. View Article : Google Scholar : PubMed/NCBI

17 

Wang H and Zheng Z: One case of parotid eosinophilic lymphogranuloma. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 28:830–831. 2014.(In Chinese). PubMed/NCBI

18 

Zhang JZ, Zhang CG and Chen JM: Thirty-five cases of Kimura's disease (eosinophilic lymphogranuloma). Br J Dermatol. 139:542–543. 1998. View Article : Google Scholar : PubMed/NCBI

19 

Koh H, Kamiishi N, Chiyotani A, Takahashi H, Sudo A, Masuda Y, Shinden S, Tajima A, Kimura Y and Kimura T: Eosinophilic lung disease complicated by Kimura's disease: A case report and literature review. Intern Med. 51:3163–3167. 2012. View Article : Google Scholar : PubMed/NCBI

20 

Naveed M, Siddiqui AA, Kowalski TE, Loren DE, Khalid A, Soomro A, Mazhar SM, Yoo J, Hasan R, Yalamanchili S, et al: A Multicenter comparative trial of a novel EUS-guided core biopsy needle (SharkCore) with the 22-gauge needle in patients with solid pancreatic mass lesions. Endosc Ultrasound. 7:34–40. 2018. View Article : Google Scholar : PubMed/NCBI

21 

Baba A, Ojiri H, Dogru M, Tanaka Y, Takahashi S, Mogami T, Kobashi Y, Yamazoe S, Nozawa Y, Ogino N, et al: An unusual clinical presentation of kimura disease manifesting with a typical cephalocervical lesion and an atypical subcutaneous hip mass lesion. Intern Med. 55:1017–1020. 2016. View Article : Google Scholar : PubMed/NCBI

22 

Wang J, Tang Z, Feng X, Zeng W, Tang W, Wu L and Jin L: Preliminary study of diffusion-weighted imaging and magnetic resonance spectroscopy imaging in Kimura disease. J Craniofac Surg. 25:2147–2151. 2014. View Article : Google Scholar : PubMed/NCBI

23 

Park SW, Kim HJ, Sung KJ, Lee JH and Park IS: Kimura disease: CT and MR imaging findings. AJNR Am J Neuroradiol. 33:784–788. 2012. View Article : Google Scholar : PubMed/NCBI

24 

Iwai H, Nakae K, Ikeda K, Ogura M, Miyamoto M, Omae M, Kaneko T and Yamashita T: Kimura disease: Diagnosis and prognostic factors. Otolaryngol Head Neck Surg. 137:306–311. 2007. View Article : Google Scholar : PubMed/NCBI

25 

Kuroda K, Kashiwagi S, Teraoka H, Kinoshita H, Nanbara M, Noda E, Chikugo T, Hirakawa K and Ohira M: Kimura's disease affecting the axillary lymph nodes: A case report. BMC Surg. 17:632017. View Article : Google Scholar : PubMed/NCBI

26 

Uysal IO, Eryilmaz MA, Salk I and Abasiyanik F: Kimura disease in the parotid gland. J Craniofac Surg. 22:337–338. 2011. View Article : Google Scholar : PubMed/NCBI

27 

Xu ZF, Yong F, Yu T, Chen YY, Gao Q, Zhou T, Pan AZ and Wu RH: Different histological subtypes of parotid gland tumors: CT findings and diagnostic strategy. World J Radiol. 5:313–320. 2013. View Article : Google Scholar : PubMed/NCBI

28 

Takeishi M, Makino Y, Nishioka H, Miyawaki T and Kurihara K: Kimura disease: Diagnostic imaging findings and surgical treatment. J Craniofacial Surg. 18:1062–1067. 2007. View Article : Google Scholar

29 

Lim WE, Tan NG and Tan KP: Radiological features in a patient with Kimura's disease. Singapore Med J. 38:125–128. 1997.PubMed/NCBI

30 

Bastos JT, Rocha CRMD, Silva PMCE, Freitas BMP, Cassia FF and Avelleira JCR: Angiolymphoid hyperplasia with eosinophilia versus Kimura's disease: A case report and a clinical and histopathological comparison. An Bras Dermatol. 92:392–394. 2017. View Article : Google Scholar : PubMed/NCBI

31 

Lu L, Chen RG, Li XQ and Wang J: Kimura disease and epithelioid hemangioma: A comparative study of 12 cases. Zhonghua Bing Li Xue Za Zhi. 34:353–357. 2005.(In Chinese). PubMed/NCBI

32 

Mantsopoulos K, Goncalves M, Koch M, Iro H and Agaimy A: Submandibular gland pleomorphic adenoma: Histopathological capsular characteristics and correlation with the surgical outcome. Ann Diagn Pathol. 34:166–169. 2018. View Article : Google Scholar : PubMed/NCBI

33 

Yu S, Zhang Z, Bao Q, Su J, Liu M, Shi Q and Cai W: Diffusion kurtosis imaging in the differential diagnosis of parotid gland disease and parotid adenolymphoma: Preliminary results. Dentomaxillofac Radiol. 16:201703882018. View Article : Google Scholar

34 

Chen Y, Wang J, Xu F, Zeng C and Liu Z: Clinicopathological features and prognosis of kimura's disease with renal involvement in Chinese patients. Clin Nephrol. 85:332–339. 2016. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhang L, Yao L, Zhou WW, Ma JN and Zhang CQ: Computerized tomography features and clinicopathological analysis of Kimura disease in head and neck. Exp Ther Med 16: 2087-2093, 2018.
APA
Zhang, L., Yao, L., Zhou, W., Ma, J., & Zhang, C. (2018). Computerized tomography features and clinicopathological analysis of Kimura disease in head and neck. Experimental and Therapeutic Medicine, 16, 2087-2093. https://doi.org/10.3892/etm.2018.6431
MLA
Zhang, L., Yao, L., Zhou, W., Ma, J., Zhang, C."Computerized tomography features and clinicopathological analysis of Kimura disease in head and neck". Experimental and Therapeutic Medicine 16.3 (2018): 2087-2093.
Chicago
Zhang, L., Yao, L., Zhou, W., Ma, J., Zhang, C."Computerized tomography features and clinicopathological analysis of Kimura disease in head and neck". Experimental and Therapeutic Medicine 16, no. 3 (2018): 2087-2093. https://doi.org/10.3892/etm.2018.6431
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang L, Yao L, Zhou WW, Ma JN and Zhang CQ: Computerized tomography features and clinicopathological analysis of Kimura disease in head and neck. Exp Ther Med 16: 2087-2093, 2018.
APA
Zhang, L., Yao, L., Zhou, W., Ma, J., & Zhang, C. (2018). Computerized tomography features and clinicopathological analysis of Kimura disease in head and neck. Experimental and Therapeutic Medicine, 16, 2087-2093. https://doi.org/10.3892/etm.2018.6431
MLA
Zhang, L., Yao, L., Zhou, W., Ma, J., Zhang, C."Computerized tomography features and clinicopathological analysis of Kimura disease in head and neck". Experimental and Therapeutic Medicine 16.3 (2018): 2087-2093.
Chicago
Zhang, L., Yao, L., Zhou, W., Ma, J., Zhang, C."Computerized tomography features and clinicopathological analysis of Kimura disease in head and neck". Experimental and Therapeutic Medicine 16, no. 3 (2018): 2087-2093. https://doi.org/10.3892/etm.2018.6431
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