Free bladder mucosa graft harvested by water‑jet: A novel, minimally invasive technique for urethral reconstruction

Wang,Zhixian; Zeng,Xiaoyong; Chen,Ruibao; Wang,Tao; Hu,Jia; Wang,Shaogang; Liu,Jihong

doi:10.3892/etm.2018.6469

September-2018 Volume 16 Issue 3

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September-2018 Volume 16 Issue 3

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Article Open Access

Free bladder mucosa graft harvested by water‑jet: A novel, minimally invasive technique for urethral reconstruction

Authors:
- Zhixian Wang
- Xiaoyong Zeng
- Ruibao Chen
- Tao Wang
- Jia Hu
- Shaogang Wang
- Jihong Liu
View Affiliations / Copyright

Affiliations: Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China

Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY_NC 4.0].
Pages: 2251-2256
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Published online on: July 18, 2018

https://doi.org/10.3892/etm.2018.6469
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Abstract

The aim of the current study was to describe a novel approach of urethral reconstruction through minimally invasive harvesting of the bladder graft via endoscopic sub‑mucosal dissection of water‑jet. The records of two patients were reviewed, who underwent transurethral endoscopic surgical bladder mucosa graft harvest by water‑jet and urethral reconstruction with informed consent. Case 1 was a 35‑year‑old male with anterior urethral stricture; case 2 was a 22‑year‑old male with secondary anterior urethral stricture and hypospadias following a failed hypospadias surgery. The two male patients successfully underwent urethral reconstruction using bladder mucosa graft harvested via endoscopic assisted by water‑jet; no perforation, cysthemorrhagia or any other postoperative bladder‑related complication was observed. Voiding cystourethrogram of case 1 indicated that the reconstructed urethra was unobstructed, and no recrudescence was observed within 4 months of follow‑up. In case 2, dysuria had disappeared completely within 1 month of follow‑up, and the urethra plate was successfully reconstructed by first‑stage. To the best of our knowledge, this is the first report to demonstrate urethral reconstruction using a bladder mucosa graft harvested by transurethral endoscopic sub‑mucosal dissection, assisted by water‑jet. Transurethral endoscopic surgery may provide a minimally invasive approach instead of the traditional open surgery for harvesting bladder mucosa graft. Urethral reconstruction conducted with bladder mucosa graft harvested via endoscopic sub‑mucosal dissection assisted by water‑jet is a feasible and safe method, and the short‑term follow‑up results are encouraging.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Free bladder mucosa graft harvested by water‑jet: A novel, minimally invasive technique for urethral reconstruction

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