|
1
|
Millecamps M, Tajerian M, Naso L, Sage EH
and Stone LS: Lumbar intervertebral disc degeneration associated
with axial and radiating low back pain in ageing SPARC-null mice.
Pain. 153:1167–1179. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Vos T, Flaxman AD, Naghavi M, Lozano R,
Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V,
et al: Years lived with disability (YLDs) for 1160 sequelae of 289
diseases and injuries 1990–2010: A systematic analysis for the
global burden of disease study 2010. Lancet. 380:2163–2196. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Gore M, Sadosky A, Stacey BR, Tai KS and
Leslie D: The burden of chronic low back pain: Clinical
comorbidities, treatment patterns and health care costs in usual
care settings. Spine (Phila Pa 1976). 37:E668–E677. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Takatalo J, Karppinen J, Taimela S,
Niinimäki J, Laitinen J, Sequeiros RB, Samartzis D, Korpelainen R,
Näyhä S, Remes J and Tervonen O: Association of abdominal obesity
with lumbar disc degeneration-a magnetic resonance imaging study.
PLoS One. 8:e562442013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Kepler CK, Ponnappan RK, Tannoury CA,
Risbud MV and Anderson DG: The molecular basis of intervertebral
disc degeneration. Spine J. 13:318–330. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Risbud MV and Shapiro IM: Role of
cytokines in intervertebral disc degeneration: Pain and disc
content. Nat Rev Rheumatol. 10:44–56. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Teague EM, Print CG and Hull ML: The role
of microRNAs in endometriosis and associated reproductive
conditions. Hum Reprod Update. 16:142–165. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Croce CM: Causes and consequences of
microRNA dysregulation in cancer. Nat Rev Genet. 10:704–714. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ellman MB, Kim JS, An HS, Chen D, KC R, An
J, Dittakavi T, van Wijnen AJ, Cs-Szabo G, Li X, et al: Toll-like
receptor adaptor signaling molecule MyD88 on intervertebral disk
homeostasis: In vitro, ex vivo studies. Gene. 505:283–290. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Iwata M, Ochi H, Asou Y, Haro H, Aikawa T,
Harada Y, Nezu Y, Yogo T, Tagawa M and Hara Y: Variations in gene
and protein expression in canine chondrodystrophic nucleus pulposus
cells following long-term three-dimensional culture. PLoS One.
8:e631202013. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Lee RC, Feinbaum RL and Ambros V: The
C. elegans heterochronic gene lin-4 encodes small RNAs with
antisense complementarity to lin-14. Cell. 75:843–854. 1993.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Bartel DP: MicroRNAs: Genomics,
biogenesis, mechanism and function. Cell. 116:281–297. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Yu X, Li Z, Shen J, Wu WK, Liang J, Weng X
and Qiu G: MicroRNA-10b promotes nucleus pulposus cell
proliferation through RhoC-Akt pathway by targeting HOXD10 in
intervetebral disc degeneration. PLoS One. 8:e830802013. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Ohrt-Nissen S, Døssing KB, Rossing M,
Lajer C, Vikeså J, Nielsen FC, Friis-Hansen L and Dahl B:
Characterization of miRNA expression in human degenerative lumbar
disks. Connect Tissue Res. 54:197–203. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Liu G, Cao P, Chen H, Yuan W, Wang J and
Tang X: MiR-27a regulates apoptosis in nucleus pulposus cells by
targeting PI3K. PLoS One. 8:e752512013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Liu H, Huang X, Liu X, Xiao S, Zhang Y,
Xiang T, Shen X, Wang G and Sheng B: miR-21 promotes human nucleus
pulposus cell proliferation through PTEN/AKT signaling. Int J Mol
Sci. 15:4007–4018. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Zhao B, Yu Q, Li H, Guo X and He X:
Characterization of microRNA expression profiles in patients with
intervertebral disc degeneration. Int J Mol Med. 33:43–50. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Diaz-Morales N, Iannantuoni F,
Escribano-Lopez I, Bañuls C, Rovira-Llopis S, Sola E, Rocha M,
Hernandez-Mijares A and Victor VM: Does metformin modulate
endoplasmic reticulum stress and autophagy in type 2 diabetic
peripheral blood mononuclear cells? Antioxid Redox Signal.
2017.(Epub ahead of print).
|
|
19
|
Nakanishi R, Kitao H, Kiniwa M, Morodomi
Y, Iimori M, Kurashige J, Sugiyama M, Nakashima Y, Saeki H, Oki E
and Maehara Y: Monitoring trifluridine incorporation in the
peripheral blood mononuclear cells of colorectal cancer patients
under trifluridine/tipiracil medication. Sci Rep. 7:169692017.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Wang HQ, Yu XD, Liu ZH, Cheng X, Samartzis
D, Jia LT, Wu SX, Huang J, Chen J and Luo ZJ: Deregulated miR-155
promotes Fas-mediated apoptosis in human intervertebral disc
degeneration by targeting FADD and caspase-3. J Pathol.
225:232–242. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Gruber HE, Hoelscher GL, Ingram JA and
Hanley EN Jr: Genome-wide analysis of pain-, nerve- and
neurotrophin-related gene expression in the degenerating human
annulus. Mol Pain. 8:632012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Xu YQ, Zhang ZH, Zheng YF and Feng SQ:
Dysregulated miR-133a mediates loss of typeII collagen by directly
targeting matrix metalloproteinase 9 (MMP9) in human intervertebral
disc degeneration. Spine (Phila Pa 1976). 41:E714–E724. 2016.
View Article : Google Scholar
|
|
24
|
Wang B, Wang D, Yan T and Yuan H:
MiR-138-5p promotes TNF-α-induced apoptosis in human intervertebral
disc degeneration by targeting SIRT1 through PTEN/PI3K/Akt
signaling. Exp Cell Res. 345:199–205. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ma JF, Zang LN, Xi YM, Yang WJ and Zou D:
MiR-125a Rs12976445 Polymorphism is associated with the apoptosis
status of nucleus pulposus cells and the risk of intervertebral dis
degeneration. Cell Physiol Biochem. 38:295–305. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Teixeira GQ, Pereira CL, Ferreira JR, Maia
AF, Gomez-Lazaro M, Barbosa MA, Neidlinger-Wilke C and Goncalves
RM: Immunomodulation of human mesenchymal stem/stromal cells in
intervertebral disc degeneration: insights from a
proinflammatory/degenerative ex vivo model. Spine (Phila Pa 1976).
2017.(Epub ahead of print).
|
|
27
|
Maidhof R, Jacobsen T, Papatheodorou A and
Chahine NO: Inflammation induces irreversible biophysical changes
in isolated nucleus pulposus cells. PLoS One. 9:e996212014.
View Article : Google Scholar : PubMed/NCBI
|
