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Case Report Open Access

De novo unbalanced translocation t(15;22)(q26.2;q12) with velo‑cardio‑facial syndrome: A case report and review of the literature

  • Authors:
    • Cristina Gug
    • Delia Huțanu
    • Monica Vaida
    • Gabriela Doroş
    • Cristina Popa
    • Ramona Stroescu
    • Gheorghe Furău
    • Cristian Furău
    • Laura Grigoriță
    • Ioana Mozos
  • View Affiliations / Copyright

    Affiliations: Department of Microscopic Morphology, Victor Babeș University of Medicine and Pharmacy, 300041 Timisoara, Romania, Department of Biology, Chemistry‑Biology‑Geography Faculty, West University Timisoara, 300115 Timisoara, Romania, Department of Anatomy and Embryology, Victor Babeș University of Medicine and Pharmacy, 300041 Timisoara, Romania, Department of Pediatrics, Victor Babeș University of Medicine and Pharmacy, 300041 Timisoara, Romania, Department of General Medicine, Faculty of Medicine, ‘Vasile Goldis’ Western University of Arad, 310118 Arad, Romania, Department of Life Sciences, Faculty of Medicine, ‘Vasile Goldis’ Western University of Arad, 310118 Arad, Romania, Department of Functional Sciences, Victor Babeș University of Medicine and Pharmacy, 300173 Timisoara, Romania
    Copyright: © Gug et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3589-3595
    |
    Published online on: August 16, 2018
       https://doi.org/10.3892/etm.2018.6609
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Abstract

The present study reports the case of a 3‑h old male with a de novo unbalanced t(15;22) translocation and velo‑cardio‑facial syndrome (VCFS), with other abnormalities. The manifestations of the condition observed in the patient included cleft palate with feeding difficulties, respiratory infection, dysmorphic face with almond‑shaped eyes, a long and wide nose, small and low‑set ears, tetralogy of Fallot, cryptorchidism and varus equinus. Standard lymphocyte cytogenetic analysis using G‑banding demonstrated a 45,XY,‑22,der (15),t(15;22)(q26.2;q12) karyotype. Fluorescent in situ hybridization with DiGeorge/VCFS TUPLE 1 confirmed 22q11 deletions. These cytogenetic aspects appear to be rare in the etiology of VCFS, as >1% of all 22q11 deletions are the result of an unbalanced translocation, which involves chromosomes 22 and another chromosome. To the best of our knowledge, this is the second reported case where the clinical features associated with VCFS are combined with an unbalanced (15;22) translocation involving the critical 22q11.2 region.
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1 

Shprintzen RJ, Goldberg RB, Lewin ML, Sidoti EJ, Berkman MD, Argamaso RV and Young D: A new syndrome involving cleft palate, cardiac anomalies, typical facies, and learning disabilities: Velo-cardio-facial syndrome. Cleft Palate J. 15:56–62. 1978.PubMed/NCBI

2 

Sandrin-Garcia P, Richieri-Costa A, Tajara EH, Carvalho-Salles AB and Fett-Conte AC: Fluorescence in situ hybridization (FISH) screening for the 22q11.2 deletion in patients with clinical features of velocardiofacial syndrome but without cardiac anomalies. Genet Mol Biol. 30:21–24. 2007. View Article : Google Scholar

3 

Gothelf D, Frisch A, Michaelovsky E, Weizman A and Shprintzen RJ: Velo-cardio-facial syndrome. J Ment Health Res Intellect Disabil. 2:149–167. 2009. View Article : Google Scholar : PubMed/NCBI

4 

Carlson C, Sirotkin H, Pandita R, Goldberg R, McKie J, Wadey R, Patanjali SR, Weissman SM, Anyane-Yeboa K, Warburton D, et al: Molecular definition of 22q11 deletions in 151 velo-cardio-facial syndrome patients. Am J Hum Genet. 61:620–629. 1997. View Article : Google Scholar : PubMed/NCBI

5 

Yunis JJ: High resolution of human chromosomes. Science. 191:1268–1270. 1976. View Article : Google Scholar : PubMed/NCBI

6 

McGowan-Jordan J, Simons A and Schmid M: ISCN 2016. Publisher Karger; 2016, View Article : Google Scholar

7 

McCance KL, Huether SE, Brashers VL and Rote NS: Pathophysiology. The biologic basis for disease in adults and children. 6th. Mosby Elsevier; Missouri: 2010

8 

McDonald-McGinn DM, Tonnesen MK, Laufer-Cahana A, Finucane B, Driscoll DA, Emanuel BS and Zackai EH: Phenotype of the 22q11. 2 deletion in individuals identified through an affected relative: Cast a wide FISHing net! Genet Med. 3:23–29. 2001.

9 

Cohen MM Jr, Gorlin RJ and Fraser FC: Craniofacial disordersEmery and Rimoin's principles and practice of medical genetics. Rimoin DL, et al: 3rd. Churchill Livingstone; New York, NY: pp. 1121–1147. 1996

10 

Gollo Dantas A, Bortolai A, Moysés-Oliveira M, Takeno Herrero S, Azoubel Antunes A, Tavares Costa-Carvalho B, Ayres Meloni V and Melaragno MI: 22q11.2 deletion syndrome due to a translocation t(6;22) in a patient conceived via in vitro fertilization. Mol Syndromol. 6:242–247. 2016. View Article : Google Scholar : PubMed/NCBI

11 

Jaquez M, Driscoll DA, Li M, Emanuel BS, Hernandez I, Jaquez F, Lembert N, Ramirez J and Matalon R: Unbalanced 15;22 translocation in a patient with manifestations of DiGeorge and velocardiofacial syndrome. Am J Med Genet. 70:6–10. 1997. View Article : Google Scholar : PubMed/NCBI

12 

Van Hove JL, McConkie-Rosell A, Chen YT, Iafolla AK, Lanman JT Jr, Hennessy MD and Kahler SG: Unbalanced translocation 46,XY,-15,+der(22)t(15;22)(q13;q11)pat: Case report and review of the literature. Am J Med Genet. 44:24–30. 1992. View Article : Google Scholar : PubMed/NCBI

13 

Fryns JP, Kleczkowska A and van den Berghe H: Frontonasal malformation and reciprocal translocation t(15;22)(q22;q13). Clin Genet. 44:46–47. 1993. View Article : Google Scholar : PubMed/NCBI

14 

Pinto-Escalante D, Ceballos-Quintal JM, Castillo-Zapata I and Canto-Herrera J: Full mosaic monosomy 22 in a child with DiGeorge syndrome facial appearance. Am J Med Genet. 76:150–153. 1998. View Article : Google Scholar : PubMed/NCBI

15 

Faed MJ, Robertson J, Beck JS, Cater JI, Bose B and Madlom MM: Features of di George syndrome in a child with 45,XX,-3,-22,+der(3),t(3;22)(p25;q11). J Med Genet. 24:225–227. 1987. View Article : Google Scholar : PubMed/NCBI

16 

Reddy KS, Sulcova V and Siassi B: Two sibs with Wolf-Hirschhorn and DiGeorge deletions resulting from an unbalanced chromosome rearrangement, 45,XX/XY, der(4)t(4;22) (p16.3;q11.2) mat,-22. J Med Genet. 33:852–855. 1996. View Article : Google Scholar : PubMed/NCBI

17 

Dundar M, Kiraz A, Tasdemir S, Akalin H, Kurtoglu S, Hafo F, Cine N and Savli H: Unbalanced 3;22 translocation with 22q11 and 3p deletion syndrome. Am J Med Genet A. 152A:1–2795. 2010. View Article : Google Scholar : PubMed/NCBI

18 

Nur BG, Cetin Z, Clark OA, Mihci E, Oygur N and Karauzum SB: 22q11.2 syndrome due to maternal translocation t(18;22) (pl1.2;q11.2). Genet Couns. 26:67–75. 2015.PubMed/NCBI

19 

McGoey RR and Lacassie Y: Paternal balanced reciprocal translocation t(9;22)(q34.3;q11.2) resulting in an infant with features of the 9q subtelomere and the 22q11 deletion syndromes due to 3:1 meiotic segregation and tertiary monosomy. Am J Med Genet A. 149A:1–2542. 2009. View Article : Google Scholar

20 

Kashevarova AA, Belyaeva EO, Nikonov AM, Plotnikova OV, Skryabin NA, Nikitina TV, Vasilyev SA, Yakovleva YS, Babushkina NP, Tolmacheva EN, et al: Compound phenotype in a girl with r(22), concomitant microdeletion 22q13.32-q13.33 and mosaic monosomy 22. Mol Cytogenet. 11:262018. View Article : Google Scholar : PubMed/NCBI

21 

Sandrin-Garcia P, Macedo C, Martelli LR, Ramos ES, Guion-Almeida ML, Richieri-Costa A and Passos GA: Recurrent 22q11.2 deletion in a sibship suggestive of parental germline mosaicism in velocardiofacial syndrome. Clin Genet. 61:380–383. 2002. View Article : Google Scholar : PubMed/NCBI

22 

Adeyinka A, Stockero KJ, Flynn HC, Lorentz CP, Ketterling RP and Jalal SM: Familial 22q11.2 deletions in DiGeorge/velocardiofacial syndrome are predominantly smaller than the commonly observed 3Mb. Genet Med. 6:517–520. 2004. View Article : Google Scholar : PubMed/NCBI

23 

Shprintzen RJ, Higgins AM, Antshel K, Fremont W, Roizen N and Kates W: Velo-cardio-facial syndrome. Curr Opin Pediatr. 17:725–730. 2005. View Article : Google Scholar : PubMed/NCBI

24 

Yagi H, Furutani Y, Hamada H, Sasaki T, Asakawa S, Minoshima S, Ichida F, Joo K, Kimura M, Imamura S, et al: Role of TBX1 in human del22q11.2 syndrome. Lancet. 362:1366–1373. 2003. View Article : Google Scholar : PubMed/NCBI

25 

Stoller JZ and Epstein JA: Identification of a novel nuclear localization signal in Tbx1 that is deleted in DiGeorge syndrome patients harboring the 1223delC mutation. Hum Mol Genet. 14:885–892. 2005. View Article : Google Scholar : PubMed/NCBI

26 

Gao S, Moreno M, Eliason S, Cao H, Li X, Yu W, Bidlack FB, Margolis HC, Baldini A and Amendt BA: TBX1 protein interactions and microRNA-96-5p regulation controls cell proliferation during craniofacial and dental development: Implications for 22q11.2 deletion syndrome. Hum Mol Genet. 24:2330–2348. 2015. View Article : Google Scholar : PubMed/NCBI

27 

Bassett AS, Chow EW, Husted J, Weksberg R, Caluseriu O, Webb GD and Gatzoulis MA: Clinical features of 78 adults with 22q11 deletion syndrome. Am J Med Genet A. 138:307–313. 2005. View Article : Google Scholar : PubMed/NCBI

28 

Oskarsdóttir S, Belfrage M, Sandstedt E, Viggedal G and Uvebrant P: Disabilities and cognition in children and adolescents with 22q11 deletion syndrome. Dev Med Child Neurol. 47:177–184. 2005. View Article : Google Scholar : PubMed/NCBI

29 

Shprintzen RJ, Wang F, Goldberg R and Marion R: The expanded velo-cardio-facial syndrome (VCF): Additional features of the most common clefting syndrome. Am J Hum Genet. 37:A771985.

30 

Jurca A, Kinga K, Bembea M, Gug C and Jurca C: Fanconi anemia with cleft palate. Rev Med Chir Soc Med Nat Iasi. 118:1074–1077. 2014.PubMed/NCBI

31 

Ryan AK, Goodship JA, Wilson DI, Philip N, Levy A, Seidel H, Schuffenhauer S, Oechsler H, Belohradsky B, Prieur M, et al: Spectrum of clinical features associated with interstitial chromosome 22q11 deletions: A European collaborative study. J Med Genet. 34:798–804. 1997. View Article : Google Scholar : PubMed/NCBI

32 

Shprintzen RJ, Goldberg R, Young D and Wolford L: The velo-cardiofacial syndrome: A clinical and genetics analysis. Pediatr. 67:167–172. 1981.

33 

Moss E, Wang P and McDonald-McGinn DM: Characteristic cognitive profile in patients with a 22q11 deletion: Verbal IQ exceeds nonverbal IQ. Am J Hum Genet. 57:A911995.

34 

Wilson DI, Burn J, Scambler P and Goodship J: DiGeorge syndrome: part of CATCH 22. J Med Genet. 30:852–856. 1993. View Article : Google Scholar : PubMed/NCBI

35 

Capriotti TM and Parker Frizzell JP: Pathophysiology. Introductory concepts and clinical perspectives. 1. F.A. Davis Company; Philadelphia, PA: 2016

36 

Capra V, Mascelli S, Garrè ML, Nozza P, Vaccari C, Bricco L, Sloan-Béna F, Gimelli S, Cuoco C, Gimelli G and Tassano E: Parental imbalances involving chromosomes 15q and 22q may predispose to the formation of de novo pathogenic microdeletions and microduplications in the offspring. PLoS One. 8:e579102013. View Article : Google Scholar : PubMed/NCBI

37 

Popovici C: Profilaxia bolilor geneticeGenetică Medicală. Covic M, Ștefănescu D and Sandovici I: 2rd. Polirom, Iaşi; pp. 619–647. 2011

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Copy and paste a formatted citation
Spandidos Publications style
Gug C, Huțanu D, Vaida M, Doroş G, Popa C, Stroescu R, Furău G, Furău C, Grigoriță L, Mozos I, Mozos I, et al: De novo unbalanced translocation t(15;22)(q26.2;q12) with velo‑cardio‑facial syndrome: A case report and review of the literature. Exp Ther Med 16: 3589-3595, 2018.
APA
Gug, C., Huțanu, D., Vaida, M., Doroş, G., Popa, C., Stroescu, R. ... Mozos, I. (2018). De novo unbalanced translocation t(15;22)(q26.2;q12) with velo‑cardio‑facial syndrome: A case report and review of the literature. Experimental and Therapeutic Medicine, 16, 3589-3595. https://doi.org/10.3892/etm.2018.6609
MLA
Gug, C., Huțanu, D., Vaida, M., Doroş, G., Popa, C., Stroescu, R., Furău, G., Furău, C., Grigoriță, L., Mozos, I."De novo unbalanced translocation t(15;22)(q26.2;q12) with velo‑cardio‑facial syndrome: A case report and review of the literature". Experimental and Therapeutic Medicine 16.4 (2018): 3589-3595.
Chicago
Gug, C., Huțanu, D., Vaida, M., Doroş, G., Popa, C., Stroescu, R., Furău, G., Furău, C., Grigoriță, L., Mozos, I."De novo unbalanced translocation t(15;22)(q26.2;q12) with velo‑cardio‑facial syndrome: A case report and review of the literature". Experimental and Therapeutic Medicine 16, no. 4 (2018): 3589-3595. https://doi.org/10.3892/etm.2018.6609
Copy and paste a formatted citation
x
Spandidos Publications style
Gug C, Huțanu D, Vaida M, Doroş G, Popa C, Stroescu R, Furău G, Furău C, Grigoriță L, Mozos I, Mozos I, et al: De novo unbalanced translocation t(15;22)(q26.2;q12) with velo‑cardio‑facial syndrome: A case report and review of the literature. Exp Ther Med 16: 3589-3595, 2018.
APA
Gug, C., Huțanu, D., Vaida, M., Doroş, G., Popa, C., Stroescu, R. ... Mozos, I. (2018). De novo unbalanced translocation t(15;22)(q26.2;q12) with velo‑cardio‑facial syndrome: A case report and review of the literature. Experimental and Therapeutic Medicine, 16, 3589-3595. https://doi.org/10.3892/etm.2018.6609
MLA
Gug, C., Huțanu, D., Vaida, M., Doroş, G., Popa, C., Stroescu, R., Furău, G., Furău, C., Grigoriță, L., Mozos, I."De novo unbalanced translocation t(15;22)(q26.2;q12) with velo‑cardio‑facial syndrome: A case report and review of the literature". Experimental and Therapeutic Medicine 16.4 (2018): 3589-3595.
Chicago
Gug, C., Huțanu, D., Vaida, M., Doroş, G., Popa, C., Stroescu, R., Furău, G., Furău, C., Grigoriță, L., Mozos, I."De novo unbalanced translocation t(15;22)(q26.2;q12) with velo‑cardio‑facial syndrome: A case report and review of the literature". Experimental and Therapeutic Medicine 16, no. 4 (2018): 3589-3595. https://doi.org/10.3892/etm.2018.6609
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