Rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: A case report

Shichi,Shunsuke; Einama,Takahiro; Suzuki,Mayu; Matsui,Hiroki; Kanazawa,Ryo; Shibuya,Kazuaki; Suzuki,Takashi; Matsuzawa,Fumihiko; Nakachi,Kohei; Hashimoto,Taku; Kondo,Nobuo; Abe,Hironori; Taketomi,Akinobu

doi:10.3892/etm.2018.6832

December-2018 Volume 16 Issue 6

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December-2018 Volume 16 Issue 6

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Case Report Open Access

Rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: A case report

Authors:
- Shunsuke Shichi
- Takahiro Einama
- Mayu Suzuki
- Hiroki Matsui
- Ryo Kanazawa
- Kazuaki Shibuya
- Takashi Suzuki
- Fumihiko Matsuzawa
- Kohei Nakachi
- Taku Hashimoto
- Nobuo Kondo
- Hironori Abe
- Akinobu Taketomi
View Affiliations / Copyright

Affiliations: Department of Surgery, Hokkaido Social Work Association Obihiro Hospital, Obihiro, Hokkaido 080‑0805, Japan, Department of Gastroenterology, Hokkaido Social Work Association Obihiro Hospital, Obihiro, Hokkaido 080‑0805, Japan, GeneticLab Co., Ltd., Sapporo, Hokkaido 060‑0009, Japan, Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060‑8638, Japan

Copyright: © Shichi et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 5224-5226
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Published online on: October 5, 2018

https://doi.org/10.3892/etm.2018.6832
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Abstract

It is often difficult to correctly diagnose patients who present with dilation of the bile duct. Cholangiocarcinoma, primary sclerosing cholangitis (PSC) and immunoglobulin (Ig)G4‑related sclerosing cholangitis must be considered as potential diagnoses for these cases. The current study presents a 73‑year‑old female patient who presented with a high fever and abdominal pain. Contrast‑enhanced computed tomography and magnetic resonance cholangiopancreatography revealed stenosis and dilation of the intrahepatic bile duct without solid components. It was suspected that the patient had intrahepatic cholangiocarcinoma. A left liver lobectomy, cholecystectomy and distal gastrectomy combined with a D2 lymph node dissection were performed. A pathological examination of the liver revealed increased fibrosis in the stroma, irregular bile duct dilation and clusters of inflamed lymph cells. No carcinoma or IgG4‑positive plasma cells were observed and the typical findings of PSC were not detected. Based on these clinical and pathological results, the diagnosis was idiopathic sclerosing cholangitis, which is particularly rare. It is often difficult to preoperatively differentiate between cholangiocarcinoma and benign bile duct stenosis.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: A case report

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Abstract

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