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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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December-2018 Volume 16 Issue 6

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Review

Bronchopulmonary dysplasia: Pathogenesis and treatment (Review)

Asfia Banu Pasha, Xiao-Qing Chen, Guo‑Ping Zhou
Pages: 4315-4321
Published online on: 19 September 2018

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Article Open Access

Probucol protects circulating endothelial progenitor cells from ambient PM2.5 damage via inhibition of reactive oxygen species and inflammatory cytokine production in vivo

Yong Chen, Ke Hu, Haoran Bu, Zhihua Si, Haihui Sun, Liming Chen, Hang Liu, Hao Xie, Peng Zhao, Le Yang, Qinghua Sun, Zhenguo Liu, Lianqun Cui, Yuqi Cui
Pages: 4322-4328
Published online on: 24 September 2018

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Article Open Access

Anti‑fibrosis activity of combination therapy with epigallocatechin gallate, taurine and genistein by regulating glycolysis, gluconeogenesis, and ribosomal and lysosomal signaling pathways in HSC‑T6 cells

Yan Li, Min Zhu, Yani Huo, Xuerong Zhang, Ming Liao
Pages: 4329-4338
Published online on: 17 September 2018

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Article Open Access

Resveratrol protects against oxidative stress by activating the Keap‑1/Nrf2 antioxidant defense system in obese‑asthmatic rats

Xiao‑Nan Li, Lu‑Yi Ma, Hong Ji, Yuan‑Hua Qin, Shan‑Shan Jin, Li‑Xin Xu
Pages: 4339-4348
Published online on: 17 September 2018

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Article Open Access

Exenatide reduces oxidative stress and cell death in testis in iron overload rat model

Suleyman Yesil, Nuran Sungu, Aydan Kilicarslan, Serife Mehlika Kuskonmaz, Halil Kara, Aysegul Kucuk, Fazli Polat, Mustafa Kavutcu, Mustafa Arslan
Pages: 4349-4356
Published online on: 26 September 2018

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Article Open Access

Comparative study of the proliferative ability of skeletal muscle satellite cells under microwave irradiation in fractures with titanium alloy internal fixation in rabbits

Yuzhen Zou, Gang Wang, Yiming Xu, Yuehong Bai
Pages: 4357-4366
Published online on: 01 October 2018

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Article Open Access

A study on the mechanism of agonists in regulating transcriptional level of pIgR in salivary gland epithelial cells

Li Huang, Chuankong Sun, Ruobing Peng, Zhiming Liu
Pages: 4367-4372
Published online on: 25 September 2018

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Article Open Access

The expression level of miR-155 in plasma and peripheral blood mononuclear cells in coronary artery disease patients and the associations of these levels with the apoptosis rate of peripheral blood mononuclear cells

Duo Zhao, Jing Zhao, Jiangbin Sun, Yanling Su, Jinfeng Jian, Huaan Ye, Jiawang Lin, Zongda Yang, Jiatao Feng, Zhiping Wang
Pages: 4373-4378
Published online on: 26 September 2018

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Article Open Access

Botulinum toxin type A induces protective autophagy in human dermal microvascular endothelial cells exposed to an in vitro model of ischemia/reperfusion injury

Yanyu Shi, Huang Lin, Jiankun Cao, Chao Cui
Pages: 4379-4386
Published online on: 17 September 2018

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Article Open Access

MicroRNA‑34a suppresses breast cancer cell proliferation and invasion by targeting Notch1 Retraction in /10.3892/etm.2025.13055

Xiaoping Rui, Haibin Zhao, Xianqiu Xiao, Li Wang, Lin Mo, Yao Yao
Pages: 4387-4392
Published online on: 17 September 2018

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Article Open Access

A promising non‑invasive index for predicting liver inflammation in chronic hepatitis B patients with alanine aminotransferase ≤2 upper limit of normal

Xue‑Ping Yu, Xiao Wen, Jing Li, Yi‑Juan Zheng, Jian‑Fei Long, Wei‑Dong Zhao, Pei‑Xue Jiang, Jing‑Wen Wu, Bei‑Di Zhu, Qi‑Rong Jiang, Fei‑Fei Yang, Zhong‑Liang Shen, Ri‑Cheng Mao, Zhi-Jun Su, Ji-Ming Zhang
Pages: 4393-4400
Published online on: 18 September 2018

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Article Open Access

Activation of astrocytes and expression of inflammatory cytokines in rats with experimental autoimmune encephalomyelitis

Lizhi Zhang, Hualei Xie, Lihai Cui
Pages: 4401-4406
Published online on: 27 September 2018

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Case Report Open Access

Type A aortic dissection in pregnant patients with fibrillin‑1 gene mutations: Two case reports and a literature review

Yuanli Lei, Zhelong Jiang, Jiaozhen Chen, Dongsheng Wang, Guangliang Hong, Shouquan Chen
Pages: 4407-4414
Published online on: 19 September 2018

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Article Open Access

Upstream transcription factor 1 prompts malignancies of cervical cancer primarily by transcriptionally activating p65 expression Retraction in /10.3892/etm.2024.12631

Wen Wang, Shujuan Yao, Hongjing Jiang, Jing Dong, Xiujuan Cui, Xiangyu Tian, Yanyan Guo, Shiqian Zhang
Pages: 4415-4422
Published online on: 18 September 2018

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Article Open Access

Influencing mechanism of magnolol on expression of BDNF and Bax in rats with cerebral ischemic stroke

Zhenbo Liu, Jun Xie, Kai Lin, Liguo Qi
Pages: 4423-4428
Published online on: 28 September 2018

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Article Open Access

Experimental research on ADSCs-NCSS in wound repair

Ai-Jun Zhang, Tao Jiang, Qiang Li, Pei-Sheng Jin, Qian Tan
Pages: 4429-4436
Published online on: 18 September 2018

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Article Open Access

Comparative study of primary pulmonary cryptococcosis with multiple nodules or masses by CT and pathology

Dongxu Wang, Chongchong Wu, Jie Gao, Shaohong Zhao, Xidong Ma, Bo Wei, Limin Feng, Yuguang Wang, Xinying Xue
Pages: 4437-4444
Published online on: 17 September 2018

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Article Open Access

Human umbilical cord‑derived mesenchymal stem cells ameliorate the enteropathy of food allergies in mice

Nannan Yan, Jie Xu, Chuanxiang Zhao, Yi Wu, Fengwei Gao, Ci Li, Wenhui Zhou, Tengfei Xiao, Xiaoming Zhou, Qixiang Shao, Sheng Xia
Pages: 4445-4456
Published online on: 19 September 2018

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Article Open Access

Cellular viability and osteogenic differentiation potential of human gingiva‑derived stem cells in 2D culture following treatment with anionic, cationic, and neutral liposomes containing doxorubicin

Hyunjin Lee, Jihwan Son, Gawon Yi, Heebeom Koo, Jun‑Beom Park
Pages: 4457-4462
Published online on: 19 September 2018

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Article Open Access

Steroid sulfatase promotes invasion through epithelial‑mesenchymal transition and predicts the progression of bladder cancer

Yasuomi Shimizu, Satoshi Tamada, Minoru Kato, Yuji Takeyama, Masaki Fujioka, Anna Kakehashi, Tatsuya Nakatani, Hideki Wanibuchi, Min Gi
Pages: 4463-4470
Published online on: 21 September 2018

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Article Open Access

PVT1 regulates inflammation and cardiac function via the MAPK/NF‑κB pathway in a sepsis model

Fang Feng, Yan Qi, Chenming Dong, Chaohui Yang
Pages: 4471-4478
Published online on: 01 October 2018

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Article Open Access

Stem cell transplantation for the treatment of patients with type 1 diabetes mellitus: A meta‑analysis

Jiadi Gan, Yingjin Wang, Xiaodong Zhou
Pages: 4479-4492
Published online on: 19 September 2018

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Article Open Access

Effects of gastrodin on 5-HT and neurotrophic factor in the treatment of patients with post-stroke depression

Gang Li, Yunxia Ma, Jinming Ji, Xingyan Si, Qijiang Fan
Pages: 4493-4498
Published online on: 19 September 2018

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Article Open Access

Antimicrobial resistance in bacterial pathogens among hospitalised patients with severe invasive infections

Ovidiu Zlatian, Andrei Theodor Balasoiu, Maria Balasoiu, Oana Cristea, Anca Oana Docea, Radu Mitrut, Demetrios A. Spandidos, Aristides M. Tsatsakis, Gabriela Bancescu, Daniela Calina
Pages: 4499-4510
Published online on: 14 September 2018

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Article Open Access

The effect of intravascular interventional embolization and craniotomy on MMP-2, MMP-9 and caspase3 in serum of intracranial aneurysm patients

Liang Zou, Yanyan Hou, Baixiang Yu, Shuang Li, Yanli Du
Pages: 4511-4518
Published online on: 14 September 2018

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Article Open Access

Axon guidance pathway genes are associated with schizophrenia risk

Zhichao Wang, Ping Li, Tong Wu, Shuangyue Zhu, Libin Deng, Guangcheng Cui
Pages: 4519-4526
Published online on: 19 September 2018

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Article Open Access

Identification and validation of differentially expressed proteins in serum of CSU patients with different duration of wheals using an iTRAQ labeling, 2D‑LC‑MS/MS

Yanyun Cao, Shunming Xu, Wei Kong, Haibin Cai, Yang Xu
Pages: 4527-4536
Published online on: 01 October 2018

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Article Open Access

MicroRNA‑106b promotes the proliferation, migration and invasion of retinoblastoma cells by inhibiting the expression of ZBTB4 protein

Wenjuan Bu, Yanhui Wang, Xiangrong Min
Pages: 4537-4545
Published online on: 01 October 2018

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Article Open Access

Contrast‑enhanced voiding urosonography with intravesical administration of ultrasound contrast agent for the diagnosis of pediatric vesicoureteral reflux

Wei Zhang, Baohuan Cai, Xiaole Zhang, Jianhua Zhou, Liru Qiu, Huiming Yi
Pages: 4546-4552
Published online on: 25 September 2018

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Article Open Access

Role of the HIF‑1 signaling pathway in chronic obstructive pulmonary disease

Xiang Fu, Fengling Zhang
Pages: 4553-4561
Published online on: 21 September 2018

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Article Open Access

Identification of mundoserone by zebrafish in vivo screening as a natural product with anti‑angiogenic activity

Kan Chen, Changqian Wang, Yuqi Fan, Jun Gu, Zhihua Han, Yue Wang, Lin Gao, Huasu Zeng
Pages: 4562-4568
Published online on: 17 September 2018

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Article Open Access

Evaluation of the effects of the combination of BMP‑2‑modified BMSCs and PRP on cartilage defects

Shiqiang Ruan, Jiang Deng, Ling Yan, Wenliang Huang
Pages: 4569-4577
Published online on: 19 September 2018

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Article Open Access

Efficacy and safety of tiotropium bromide combined with budesonide/formoterol in the treatment of moderate to severe chronic obstructive pulmonary disease

Daguo Zhao, Chunhua Ling, Qiang Guo, Jun Jin, Hua Xu
Pages: 4578-4584
Published online on: 19 September 2018

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Article Open Access

Study of non‑contrast helical computed tomography in evaluating holmium laser lithotripsy for urinary calculus

Jia Mi, Zudong Yin, Xinyi Zhang, Wushi Han, Xiangsen Jiang, Changbin Wang, Xiaobao Li, Zhangzhu Li, Lei Yu, Liang Yin, Lin Cheng
Pages: 4585-4589
Published online on: 19 September 2018

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Article Open Access

Diagnostic value of medical thoracoscopy for undiagnosed pleural effusions

Rui‑Lin Chen, Yong‑Qing Zhang, Jun Wang, Hua Wu, Shu‑Mei Yang
Pages: 4590-4594
Published online on: 17 September 2018

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Article Open Access

Concentration‑dependent effects of rapamycin on proliferation, migration and apoptosis of endothelial cells in human venous malformation

Yameng Si, Hanchen Chu, Weiwen Zhu, Tao Xiao, Xiang Shen, Yu Fu, Rongyao Xu, Hongbing Jiang
Pages: 4595-4601
Published online on: 19 September 2018

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Article Open Access

Dysregulated microRNA expression profiles in gastric cancer cells with high peritoneal metastatic potential

Yaning Feng, Feihu Bai, Yanjie You, Fangyun Bai, Chuanxia Wu, Ruijuan Xin, Xue Li, Yongzhan Nie
Pages: 4602-4608
Published online on: 19 September 2018

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Article Open Access

Response of regulatory T cells to classic heat stroke in mice

Jie Hu, Hong‑Jun Kang, Chao Liu, Pan Hu, Meng‑Meng Yang, Fei‑Hu Zhou
Pages: 4609-4615
Published online on: 19 September 2018

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Article Open Access

MicroRNA‑21 inhibits lipopolysaccharide‑induced acute lung injury by targeting nuclear factor‑κB

Wei‑Dong Zhu, Jia Xu, Mao Zhang, Tie‑Ming Zhu, Yun‑Hua Zhang, Ke Sun
Pages: 4616-4622
Published online on: 24 September 2018

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Article Open Access

BMP9 overexpressing adipose‑derived mesenchymal stem cells promote cartilage repair in osteoarthritis-affected knee joint via the Notch1/Jagged1 signaling pathway

Xinwei Liu, Mingchang Du, Yu Wang, Songbo Liu, Xianmin Liu
Pages: 4623-4631
Published online on: 18 September 2018

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Article Open Access

sTLR4/sMD‑2 complex alleviates LPS‑induced acute lung injury by inhibiting pro‑inflammatory cytokines and chemokine CXCL1 expression

Jie Meng, Yan Zou, Jifei Chen, Fengxian Qin, Xiang Chen, Xiaoli Chen, Shengming Dai
Pages: 4632-4638
Published online on: 17 September 2018

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Article Open Access

Targeting lung cancer initiating cells by all‑trans retinoic acid‑loaded lipid‑PLGA nanoparticles with CD133 aptamers

Yu Zhang, Juan Zhao, Jing Sun, Lu Huang, Qingfeng Li
Pages: 4639-4649
Published online on: 19 September 2018

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Article Open Access

Thoracoscope combined with internal support system of chest wall in open reduction and internal fixation for multiple rib fractures

Honggang Xia, Pengzhi Zhu, Jing Li, Deqing Zhu, Zhongyi Sun, Limin Deng, Yongmin Zhang, Dongbin Wang
Pages: 4650-4654
Published online on: 01 October 2018

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Article Open Access

miR‑21‑5p induces cell proliferation by targeting TGFBI in non‑small cell lung cancer cells

Liang Yan, Jinzhu Ma, Yi Wang, Jiawei Zan, Zhen Wang, Yu Zhu, Yiping Zhu, Liefeng Ling, Long Cao, Xin Liu, Shu Li, Lei Xu, Zhilin Qi, Liuwang Nie, Yao Zhang
Pages: 4655-4663
Published online on: 18 September 2018

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Article Open Access

A retrospective analysis of 1,231 patients with anemia after surgical treatment of hyperthyroidism

Ruisha Tu, Hongfeng Shen, Qicong Zhu, Gaocai Mao, Xiaojiang Xu, Shuyong Yu
Pages: 4664-4668
Published online on: 14 September 2018

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Article Open Access

Correlation between coronary atherosclerosis calcification and epicardial adipose tissue volume in patients with nephropathy

Hong Zuo, Ying Zhang, Qiaojuan Ma
Pages: 4669-4673
Published online on: 27 September 2018

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Article Open Access

Fluorescence in situ hybridization comparison of the prognostic factors in adult and pediatric acute lymphoblastic leukemia: A retrospective analysis of 282 cases

Pengfei Cao, Yalan Yu, Wei Wang, He Xu, Yuxiang He
Pages: 4674-4684
Published online on: 02 October 2018

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Article Open Access

Effects of dexmedetomidine on postoperative cognitive function in patients undergoing coronary artery bypass grafting

Zheng Gong, Jun Li, Yuling Zhong, Xuehai Guan, Ailan Huang, Li Ma
Pages: 4685-4689
Published online on: 19 September 2018

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Article Open Access

Abnormal expression of miR‑4784 in chondrocytes of osteoarthritis and associations with chondrocyte hyperplasia

Jing Liu, Qiaolong Yu, Yanhui Ye, Yan Yan, Xin Chen
Pages: 4690-4694
Published online on: 14 September 2018

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Article Open Access

miR-183 and miR-141 in lesion tissues are potential risk factors for poor prognosis in patients with infected abdominal aortic aneurysm

Chunying Meng, Zeheng Guo, Dagang Li, Hanwei Li, Jun Zhou, Dingguo Wen, Bin Luo
Pages: 4695-4699
Published online on: 13 September 2018

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Article Open Access

Correlation between histopathological grading and shear‑wave elastography in evaluating invasive carcinoma of no special type

Yi‑Cheng Zhu, Yuan Zhang, Shu‑Hao Deng, Quan Jiang, Deng‑Shan Wang
Pages: 4700-4706
Published online on: 24 September 2018

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Article Open Access

Expression of microRNA-23b in patients with sepsis and its effect on leukocytes and the expression of E-selectin and ICAM-1

Hao Ou, Xianzhong Xiao, Yu Jiang, Yue Peng, Mingshi Yang, Min Gao
Pages: 4707-4711
Published online on: 18 September 2018

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Article Open Access

Effect and clinical value of coagulation test on adverse reactions of blood transfusion in patients with major bleeding in ectopic pregnancy

Fanjiu Kong, Yingbo Li, Xiaoxin Liu
Pages: 4712-4716
Published online on: 27 September 2018

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Article Open Access

Effects of permanent cardiac pacemaker implantation on vascular endothelial function, blood coagulation and cardiac function in patients with bradycardia

Xinling Zhang, Yan Li, Nan Wang, Chunxiang Zhang, Debing Zhang, Qiang Li
Pages: 4717-4721
Published online on: 28 September 2018

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Article

Effects of androgen and progestin on the proliferation and differentiation of osteoblasts

Xinchen Wu, Mengqi Zhang
Pages: 4722-4728
Published online on: 19 September 2018

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Article

Differential roles of p38 MAPK and ERK1/2 in angiopoietin‑2‑mediated rat pulmonary microvascular endothelial cell apoptosis induced by lipopolysaccharide

Shi Li, Mingmei Zhong, Yuan Yuan, Lin Zhang
Pages: 4729-4736
Published online on: 01 October 2018

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Article

TNF‑α increases the expression of inflammatory factors in synovial fibroblasts by inhibiting the PI3K/AKT pathway in a rat model of monosodium iodoacetate‑induced osteoarthritis

Hongxi Li, Shujuan Xie, Yunlong Qi, Huazhe Li, Rui Zhang, Yongyun Lian
Pages: 4737-4744
Published online on: 19 September 2018

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Article

Effect of the emphysema subtypes of patients with chronic obstructive pulmonary disease on airway inflammation and COTE index

Zheng Liu, Fang Shi, Jun‑Xia Liu, Chang‑Lan Gao, Meng‑Miao Pei, Jing Li, Pei‑Xiu Li
Pages: 4745-4752
Published online on: 27 September 2018

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Article

miR‑671‑5p inhibits gastric cancer cell proliferation and promotes cell apoptosis by targeting URGCP

Tiefeng Qiu, Keping Wang, Xianwen Li, Jianhua Jin
Pages: 4753-4758
Published online on: 01 October 2018

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Article

MicroRNA‑373 promotes cell migration via targeting salt‑inducible kinase 1 expression in melanoma

Xinping Bai, Ming Yang, Yi Xu
Pages: 4759-4764
Published online on: 21 September 2018

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Article

Characterization and evolution of intestine injury at the anhepatic phase in portal hypertensive rats

Guijun Ren, Xiaoye Yuan, Xin Zhao, Qingchun Hao, Jinglin Cao, Yang Wang, Qingjun Gao, Jian Dou, Qiang Zeng
Pages: 4765-4771
Published online on: 27 September 2018

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Article

Clinicopathological analysis of the hydroa vacciniforme‑like lymphoproliferative disorder with natural killer cell phenotype compared with cutaneous natural killer T‑cell lymphoma

Guan‑Nan Wang, Yong Cui, Wu‑Gan Zhao, Ling Li, Xu‑Dong Zhang, Yu Chang, Xian‑Zheng Gao, Ye Li, Ming‑Zhi Zhang, Wen‑Cai Li
Pages: 4772-4778
Published online on: 19 September 2018

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Article

Quantum dot‑based fluorescent probes for targeted imaging of the EJ human bladder urothelial cancer cell line

Run Yuan, Ting Rao, Fan Cheng, Wei‑Min Yu, Yuan Ruan, Xiao‑Bin Zhang, Stéphane Larré
Pages: 4779-4783
Published online on: 28 September 2018

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Article

CB2R induces a protective response for epileptic seizure via the PI3K 110α‑AKT signaling pathway

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Long non‑coding RNA HOTAIR overexpression improves premature ovarian failure by upregulating Notch‑1 expression

Wei Zhao, Liwei Dong
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MicroRNA‑218 enhances gastric cancer cell cisplatin sensitivity by targeting survivin

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Elevated circulating macrophage inhibitory cytokine 1 is a biological marker for the diagnosis and prognosis of osteosarcoma

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Overexpression of epithelial cell adhesion molecule as a predictor of poor outcome in patients with hepatocellular carcinoma

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LncRNA HOTAIR improves diabetic cardiomyopathy by increasing viability of cardiomyocytes through activation of the PI3K/Akt pathway

Kun Qi, Jianke Zhong
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Long non‑coding RNA LINC01410 promotes colon cancer cell proliferation and invasion by inhibiting miR‑3128

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PTEN in propofol‑induced insulin resistance in mouse primary hepatocytes

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Regulatory role of miRNA‑26a in neonatal sepsis

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AMPK/TSC2/mTOR pathway regulates replicative senescence of human vascular smooth muscle cells

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Oridonin enhances the radiosensitivity of lung cancer cells by upregulating Bax and downregulating Bcl‑2

Sirui Li, Dan Shi, Liangyu Zhang, Fang Yang, Guanghui Cheng
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Berberine alleviates amyloid β25‑35‑induced inflammatory response in human neuroblastoma cells by inhibiting proinflammatory factors

Jing Xu, Wenlan Wu, Hong Zhang, Li Yang
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Diagnostic accuracy of magnetic resonance angiography for Budd‑Chiari syndrome: A meta‑analysis

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Long non‑coding RNA LINC01503 promotes colorectal cancer cell proliferation and invasion by regulating miR‑4492/FOXK1 signaling

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Surgical strategy for temporal lobe epilepsy with dual pathology and incomplete evidence from EEG and neuroimaging

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A pilot study: The association between physical activity level using by accelerometer and postoperative complications after hepatic resection

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The exogenous administration of CB2 specific agonist, GW405833, inhibits inflammation by reducing cytokine production and oxidative stress

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MicroRNA‑214 promotes the proliferation, migration and invasion of gastric cancer MKN28 cells by suppressing the expression of Dact2

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Electroacupuncture stimulates the proliferation and differentiation of endogenous neural stem cells in a rat model of ischemic stroke

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Ellagic acid ameliorates learning and memory impairment in APP/PS1 transgenic mice via inhibition of β‑amyloid production and tau hyperphosphorylation

Lili Zhong, Hong Liu, Weijia Zhang, Xu Liu, Bo Jiang, Hongxin Fei, Zhongren Sun
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Inhibitory effect of microRNA‑455‑5p on biological functions of esophageal squamous cell carcinoma Eca109 cells via Rab31

Ying Liu, Yanping Tang, Ping Li
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Long non‑coding RNA SNHG20 promotes nasopharyngeal carcinoma cell migration and invasion by upregulating TGF‑β1

Caibo Sun, Yuning Sun, Endong Zhang
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TNFAIP8 promotes cell growth by regulating the Hippo pathway in epithelial ovarian cancer

Yao Xie, Fei Zhou, Xia Zhao
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Endothelial PAS domain protein 1 gene hypomethylation is associated with colorectal cancer in Han Chinese

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Network analysis of differentially expressed smoking‑associated mRNAs, lncRNAs and miRNAs reveals key regulators in smoking‑associated lung cancer

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Characteristics of pulmonary infection after mitral valve repair in patients with metabolic syndrome and its relationship with blood pressure, blood glucose and blood lipid

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Imbalance of M1/M2 macrophages is linked to severity level of knee osteoarthritis

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Anti‑inflammatory effects of bone marrow mesenchymal stem cells on mice with Alzheimer's disease

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Functional changes of airway epithelial cells and mitochondria in rat models of asthenic lung and phlegm blocking combined with cough variant asthma

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Bioinformatics analysis reveals different gene expression patterns in the annulus fibrosis and nucleus pulpous during intervertebral disc degeneration

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Bone morphogenetic protein‑12 inducing tenogenic differentiation of mesenchymal stem cells enhances healing of linea alba incision

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Crocin promotes apoptosis of human skin cancer cells by inhibiting the JAK/STAT pathway

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Beneficial effects of percutaneous minimally invasive surgery for patients with fractures in the thoracic spine

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Gut microbiota‑metabolism axis in digestive tumors: Emerging targets for novel therapies (Review)

Zhendong Yang, Siyu Wu, Xueying Yang, Bowen Sui
Article Number: 113
Published online on: 17 February 2026

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Retraction Open Access

[Retracted] Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis

Ying Xu, Guo-Jing Dai, Qian Liu, Zhen-Li Liu, Zhi-Qian Song, Li Li, Wei-Heng Chen, Na Lin
Article Number: 112
Published online on: 16 February 2026

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Article Open Access

Metformin triggers apoptosis via endoplasmic reticulum stress in HER2‑positive breast cancer cell lines

Eser Çakmak, Birşen Bilgici
Article Number: 111
Published online on: 13 February 2026

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Article Open Access

Identification of a novel PLS1 heterozygous variant causing autosomal dominant non‑syndromic hearing loss

Chenxi Yang, Yao Xiong, Dongyang Wang, Juanzi Shi
Article Number: 110
Published online on: 12 February 2026

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Case Report

Familial SCA14: A case report with review

Han-Ke Huang, Chia-Ju Lee, Wen-Ling Cheng, Hui-Ju Chang, Chin-San Liu
Article Number: 109
Published online on: 12 February 2026

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Article Open Access

Efficacy of opioids in combination with gabapentin vs. opioids alone in the treatment of patients with cancer‑related pain due to bone metastases from malignant neoplasms: A meta‑analysis

Hongli Zhou, Jun Feng, Zuolei Tang
Article Number: 108
Published online on: 12 February 2026

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Article Open Access

Drug‑related problems in pediatric patients with chronic kidney disease: A single‑center prospective study

Xingxing Liu, Yue Li, Zhen Mao, Xin Wang, Shan Zhao, Qiu Han, Jia Liu, Yan Zhou, Shi Li, Bing Chen, Yongfu Hang, Wan Yan, Xiaoye Jin
Article Number: 107
Published online on: 12 February 2026

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Article Open Access

Effects of the WNT signaling pathway on inflammation and fibrosis in idiopathic pulmonary fibrosis: Clinical, radiological and molecular evaluation

İlknur Kaya, Ayşe Koçak Sezgi̇n, Meliha Koldemi̇r Gündüz, Şebnem Emine Parspur, Feride Marim, Mehmet Doğan, Ümran Toru Erbay
Article Number: 106
Published online on: 11 February 2026

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Article

IGFBP1 as a metabolic‑neurodegenerative biomarker in spinocerebellar ataxia type 3

Chungmin Chiu, Wenling Cheng, Tatsung Lin, Huiju Chang, Yujun Chang, Shihli Su, Chiaju Lee, Henhong Chang, Chinsan Liu
Article Number: 105
Published online on: 10 February 2026

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Case Report Open Access

Endodontic re‑treatment of the mandibular first molar with six root canals: A case report

Chen Wang, Mengyu Liu
Article Number: 104
Published online on: 09 February 2026

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Retraction Open Access

[Retracted] Effect of enhanced expression of COL8A1 on lymphatic metastasis of hepatocellular carcinoma in mice

Zhen-Hai Ma, Jin-Hui Ma, Li Jia, Yong-Fu Zhao
Article Number: 103
Published online on: 09 February 2026

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Article Open Access

Surgical treatment of extrahepatic intraabdominal hydatid cysts: A single‑centre retrospective analysis

Fatih Dal, Tutkun Talih, Muhammet Akyüz, Uğur Topal, Gökhan Sönmez, Erdoğan Mütevelli Sözüer, Hizir Yakup Akyildiz, Mustafa Karaağaç, Sedat Çarkit, Doğan Gürkan İslam
Article Number: 102
Published online on: 09 February 2026

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Article Open Access

Analysis of independent prognostic factors for the occurrence and severity of heart failure after chemotherapy in patients with small cell lung cancer 

Jieqiong Zhao, Xiao Wang, Xiaoxue Liu, Wei Zhao, Xia Lu, Ruijie Li, Xiang Sun
Article Number: 101
Published online on: 09 February 2026

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Case Report

Sagittal sinus thrombosis in pregnancy: A case report

Zaheera Saadia, Misbah Ilyas, Jayd Saud Althwiny, Fai Alaqel, Alanoud Abdullah Alsufayri, Lujain Husain Almutairi
Article Number: 100
Published online on: 05 February 2026

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Article

Elevated PGE2 and COX‑2 expression in villous adenoma: Implications for electrolyte depletion syndrome

Shiki Fujino, Hiroyuki Fukuda, Katsuki Danno, Takashi Takeda, Masaya Higashiguchi, Kozo Noguchi, Takefumi Hirao, Aya Ito, Norikatsu Miyoshi, Yoshio Oka
Article Number: 99
Published online on: 04 February 2026

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Article Open Access

Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation

Yu Lu, Xiaomei Zhou, Yiyu Guo, Fengrui Zhang, Jirong Wang, Jinhong Ge, Yan Xiao, Dengke Yang
Article Number: 98
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Glibenclamide exacerbates adriamycin‑induced cardiotoxicity by activating oxidative stress‑induced endoplasmic reticulum stress in rats

Meng-Lin Liu, Meng-Long Wang, Jing-Jun Lv, Jie Wei, Jun Wan
Article Number: 97
Published online on: 04 February 2026

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Review

Key role of the autonomic nervous system in breast cancer (Review)

Min Wu, Zhiwu Zhang, Lu Zhou, Shiqi Liu, Qing Chen, Cui Guo, Shasha Zhao, Xuedan Chen
Article Number: 96
Published online on: 04 February 2026

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Review Open Access

Senescent hepatic stellate cells drive inflammation and disease progression in MASH (Review)

Zhiqi Han, Yiran She, Di Wu, Nuo Zhang, Zheyuan Liu, Zhongyuan Wang, Xiaoying Zhou, Shuo Li
Article Number: 95
Published online on: 04 February 2026

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Article Open Access

PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

Zilong Zhang, Hangyu Zhou, Diliyaer Adili, Wei Zhu, Yong Liu, Wenzheng Zhou, Zhao Wang, Jie Li
Article Number: 94
Published online on: 04 February 2026

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Case Report

A novel human papillomavirus‑induced ‘doughnut wart’ lesion treated with 5‑aminolevulinic acid photodynamic therapy: A case report

Ke Li, Yitao Qian, Wenjing Zha, Lei Shi
Article Number: 93
Published online on: 04 February 2026

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Case Report Open Access

Comprehensive diagnosis and individualized treatment of multiple primary lung cancer: A case report

Guoxiong Zeng, Yunyan Zhou, Wang Wan, Biao Deng, Chunyuan Chen, Zhu Liang
Article Number: 92
Published online on: 03 February 2026

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Review Open Access

Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review)

Hong Zhou, Wenwen Yu, Jiaming Lei, Runzhi Chang, Yingjia Cheng, Guorui Wang, Li Lin
Article Number: 91
Published online on: 03 February 2026

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Case Report Open Access

A rare upstream regulatory region mutation in APC presenting as classical familial adenomatous polyposis: A case report and literature review

Chi-Han Yang, Yen-Cheng Chen, Tsung-Kun Chang, Wei-Chih Su, Ching-Wen Huang, Hsiang-Lin Tsai, Jaw-Yuan Wang
Article Number: 90
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] lncRNA MIAT promote cell invasion and migration in esophageal cancer

Weiguo Zhang, Qiang Chen, Caipeng Lei
Article Number: 89
Published online on: 02 February 2026

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Review Open Access

Mitochondria‑driven ferroptosis in intervertebral disc degeneration: A novel target in age‑related spinal diseases (Review)

Yang Hou, Xiaolei Yang, Duorun Qiu, Lei Liu, Jiangang Shi, Yongfei Guo
Article Number: 88
Published online on: 02 February 2026

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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

Jingxian Li, Fang Wang, Yuanshu Du, Yonghui Wang
Article Number: 87
Published online on: 02 February 2026

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Case Report Open Access

Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report

Bin He, Lin Ling Li, Ting Yu, Yu Tan, Ling Zhang
Article Number: 86
Published online on: 29 January 2026

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Article Open Access

Myrrh ameliorates endometriosis by enhancing ER stress‑related apoptotic cell death

Bo-Sung Kim, Minkyoung Cho, Jung Ho Han, Jung-Sook Jin, Sung-Jin Bae, Yunju Jo, Dongryeol Ryu, Yerim Joo, Seon Beom Kim, Jongkil Joo, Inhye Kim, Ki-Tae Ha
Article Number: 85
Published online on: 29 January 2026

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May-2026 Volume 31 Issue 5

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Impact Factor: 2.3

Review Open Access

FCER1G: A multifunctional regulator in the immune microenvironment (Review)

Yuyu Zhang, Jinglan Wang, Wenting He, Tao Liu
Article Number: 146
Published online on: 26 March 2026

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Article Open Access

A nomogram for predicting recurrence‑free survival in patients with high‑risk GIST receiving adjuvant imatinib: A nationwide registry study

Chun-Nan Yeh, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh, Li-Yaun Bai, Jun-Te Hsu, I-Shu Chen, Li-Tzong Chen, Hui-Jen Tsai, The Taiwan Cooperative Oncology Group Gist Study Group
Article Number: 145
Published online on: 24 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 144
Published online on: 23 March 2026

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Risk factors for severe retinopathy of prematurity: A retrospective case‑control study

Qingmin Ma, Xi Lv, Jiangya Wang, Kejun Li, Wenwen Τang
Article Number: 143
Published online on: 20 March 2026

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Article Open Access

Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial

Dawei Wang, Jingya Dai, Shumei Li, Yaping Liu, Xiaofeng Xing, Lei Huang, Qijun Pang
Article Number: 142
Published online on: 19 March 2026

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Article Open Access

Maresin 1 activates autophagy through SIRT1/PPAR‑γ signaling to mitigate high glucose‑induced pyroptosis in human retinal pigment epithelial cells

Jun Zhang, Ding Zhao, Yuanqing Zhang, Haoxiang Sun, Zhipeng Yan, Haiyan Sun
Article Number: 141
Published online on: 19 March 2026

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Review Open Access

Advances in new ultrasound technologies in targeted prostate biopsy (Review)

Tingting Jin, Liying Wang, Shusen Zheng
Article Number: 140
Published online on: 19 March 2026

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Review Open Access

Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review)

Min Liu, Kui Su
Article Number: 139
Published online on: 19 March 2026

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Article Open Access

Immunohistochemical evaluation of gastric‑type markers in primary extramammary Paget disease: Differential MUC5AC expression between in situ and invasive lesions

Naoto Kohno, Mitsuaki Ishida, Shizuka Ono, Yoshinobu Hirose
Article Number: 138
Published online on: 19 March 2026

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Review Open Access

Disrupted beginnings: Neurodevelopmental outcomes of COVID‑19 lockdowns in early childhood (Review)

Ioanna Giannopoulou, Vasiliki Efstathiou, Maria-Ioanna Stefanou, Panagiota Korkoliakou, James N. Tsoporis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 137
Published online on: 16 March 2026

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Retraction Open Access

[Retracted] Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF‑κB and PI3K/AKT pathways

Ling Sun, Jing Zhang
Article Number: 136
Published online on: 16 March 2026

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Article Open Access

Effects of fullerenol C60 on the liver, heart and brain tissues of streptozotocin‑induced diabetic rats with sepsis

Necmiye Şengel, Ömer Kubat, Laman Farajsoylu, Ahmet Çağri Büyükkasap, Muharrem Atli, Şaban Cem Sezen, Hasan Bostanci, Kürşat Dikmen, Işin Güneş, Fatma Er, Mustafa Kavutçu, Mustafa Arslan
Article Number: 135
Published online on: 13 March 2026

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Article Open Access

Long non‑coding RNA KCNQ1OT1 promotes ovarian cancer cell malignant characteristics by targeting the miR‑140‑5p/KLK10 axis

Renjie Duan, Zhenyu Tao, Shun Tao, Aichen Yang, Xu Yang, Changzheng Li, Xiaoxiang Zhu, Kexin Zhang, Zhuofu Li, Shanjun Tao
Article Number: 134
Published online on: 11 March 2026

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Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
Published online on: 09 March 2026

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Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
Published online on: 09 March 2026

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Case Report Open Access

Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
Published online on: 06 March 2026

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Case Report

Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report

Yajun Yao, Ge-Hong Dong, De-Cai Tian
Article Number: 129
Published online on: 06 March 2026

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Article Open Access

Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta‑analysis

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 128
Published online on: 06 March 2026

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Article

Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Case Report

Management after two consecutive suction losses during small‑incision lenticule extraction: A case report

Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
Published online on: 03 March 2026

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Case Report Open Access

Hematemesis resulting from mesenteric venous thrombosis: A case report

Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
Article Number: 125
Published online on: 02 March 2026

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Article

Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Article

Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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Article Open Access

RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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Article Open Access

A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
Published online on: 27 February 2026

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Case Report

A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Review Open Access

Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review)

Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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