Arterial blood gas and acid‑base balance in patients with pregnancy‑induced hypertension syndrome

Cao,Yali; Wang,Meichun; Yuan,Yuchao; Li,Cong; Bai,Qinglin; Li,Min

doi:10.3892/etm.2018.6893

Arterial blood gas and acid‑base balance in patients with pregnancy‑induced hypertension syndrome

Authors:
- Yali Cao
- Meichun Wang
- Yuchao Yuan
- Cong Li
- Qinglin Bai
- Min Li
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Affiliations: Department of Obstetrics, The First People's Hospital of Jining, Jining, Shandong 272011, P.R. China, Department of Clinical Laboratory, Yantaishan Hospital of Yantai, Yantai, Shandong 264025, P.R. China, Department of Ultrasound, People's Hospital of Zhangqiu District, Jinan, Shandong 250000, P.R. China, Department of Otolaryngology, People's Hospital of Zhangqiu District, Jinan, Shandong 250000, P.R. China, Department of Operating Room, People's Hospital of Zhangqiu District, Jinan, Shandong 250000, P.R. China
Published online on: October 24, 2018 https://doi.org/10.3892/etm.2018.6893
Pages: 349-353
Copyright: © Cao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

This study aimed to investigate the expression of arterial blood gas and acid‑base balance in patients with pregnancy‑induced hypertension syndrome and their influence on newborns. A total of 348 patients with pregnancy‑induced hypertension syndrome (research group) admitted and treated in the First People's Hospital of Jining from March 2013 to March 2016 were retrospectively analyzed, and another 156 cases of healthy pregnant women who were physically examined were selected as the control group. Blood gas analysis was performed on pregnant women, and pH value, partial pressure of oxygen (PO2), partial pressure of carbon dioxide (PCO2), bicarbonate radical (HCO3‑) and base excess (BE) were included as test indexes. Apgar score was made for newborns for neonatal asphyxia. The evaluation was performed at 1, 5, and 10 min after birth to analyze the correlation between the maternal arterial blood pH and the neonatal Apgar score. The pH value, and PO2 and HCO3‑ levels in the research group were lower than those in the control group (p<0.05). PCO2 and BE levels in the research group were higher than those in the control group (p<0.05). The incidence of neonatal mild asphyxia (Apgar score, 4‑6 points) and neonatal severe asphyxia (Apgar score, <4 points) in the research group were higher than that in the control group (p<0.05). The Apgar score of newborns was positively correlated with the pH value of the arterial blood of pregnant women. Blood gas analysis in patients with pregnancy‑induced hypertension syndrome is useful to a certain extent to evaluate the condition of the patient. The combination of the pH value of the patient and the Apgar score of the newborns may help improve the judgement rate of neonatal asphyxia so as to improve the quality of childbirth by early monitoring and intervention of the newborns.

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