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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January-2019 Volume 17 Issue 1

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Article Open Access

Oligo‑fucoidan improved unbalance the Th1/Th2 and Treg/Th17 ratios in asthmatic patients: An ex vivo study

Chao‑Huei Yang, Jing‑Jing Tian, Wang‑Sheng Ko, Chia‑Ju Shih, Ya‑Ling Chiou
Pages: 3-10
Published online on: 07 November 2018

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Article Open Access

Human amniotic membrane intra‑articular injection prevents cartilage damage in an osteoarthritis model

I. A. Marino‑Martínez, A. G. Martínez‑Castro, V. M. Peña‑Martínez, C. A. Acosta‑Olivo, F. Vílchez‑Cavazos, A. Guzmán‑López, Edelmiro Pérez Rodríguez, V. J. Romero‑Díaz, J. A. Ortega‑Blanco, J. Lara‑Arias
Pages: 11-16
Published online on: 02 November 2018

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Article Open Access

The HMGB1‑RAGE/TLR‑TNF‑α signaling pathway may contribute to kidney injury induced by hypoxia

Cheng Zhang, Hui Dong, Fengwei Chen, Yunxia Wang, Jing Ma, Guangfa Wang
Pages: 17-26
Published online on: 06 November 2018

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Article Open Access

Expression of TLR4 gene is downregulated in acquired immune deficiency syndrome‑associated Kaposi's sarcoma

Xiaobo Lu, Xuefeng Wan, Xiaoran Li, Kejun Pan, Wubuli Maimaitiaili, Yuexin Zhang
Pages: 27-34
Published online on: 08 November 2018

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Article Open Access

Effects of general anesthesia with combined epidural anesthesia on inflammatory response in patients with early‑stage gastric cancer undergoing tumor resection

Weigang Liu, Lixia Wu, Miao Zhang, Liming Zhao
Pages: 35-40
Published online on: 29 October 2018

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Article Open Access

Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits the growth and aggressiveness of colon carcinoma via the exogenous apoptosis signaling pathway

Hongyan Gong, Weicai Cheng, Yong Wang
Pages: 41-50
Published online on: 30 October 2018

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Article Open Access

Comparison of neuroendocrine dysfunction in patients with adamantinomatous and papillary craniopharyngiomas

Ying Feng, Ming Ni, Yong‑Gang Wang, Li‑Yong Zhong
Pages: 51-56
Published online on: 12 November 2018

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Article

Swimming intervention alleviates insulin resistance and chronic inflammation in metabolic syndrome

Jiye Tan, Lili Guo
Pages: 57-62
Published online on: 30 October 2018

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Article Open Access

HIF‑α/PKM2 and PI3K‑AKT pathways involved in the protection by dexmedetomidine against isoflurane or bupivacaine‑induced apoptosis in hippocampal neuronal HT22 cells

Fangping Bao, Xianhui Kang, Qing Xie, Jian Wu
Pages: 63-70
Published online on: 12 November 2018

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Article Open Access

Rho signaling pathway enhances proliferation of PASMCs by suppressing nuclear translocation of Smad1 in PAH

Hongwei Wei, Dongqing Zhang, Lili Liu, Wei Xia, Fuhai Li
Pages: 71-78
Published online on: 08 November 2018

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Article Open Access

3D printed poly(ε‑caprolactone) scaffolds function with simvastatin‑loaded poly(lactic‑co‑glycolic acid) microspheres to repair load‑bearing segmental bone defects

Zhan‑Zhao Zhang, Hui‑Zhong Zhang, Zhi‑Yong Zhang
Pages: 79-90
Published online on: 09 November 2018

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Article Open Access

TBL1XR1 as a potential therapeutic target that promotes epithelial‑mesenchymal transition in lung squamous cell carcinoma

Yuehua Zhao, Hao Lin, Jingwei Jiang, Mengxi Ge, Xiaohua Liang
Pages: 91-98
Published online on: 12 November 2018

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Article Open Access

The combination of NVP‑BEZ235 and rapamycin regulates nasopharyngeal carcinoma cell viability and apoptosis via the PI3K/AKT/mTOR pathway

Hui Luo, Yu‑Yu Yu, Hong‑Mei Chen, Wei Wu, Yong Li, Hong Lin
Pages: 99-106
Published online on: 29 October 2018

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Article Open Access

Glabridin attenuates endothelial dysfunction and permeability, possibly via the MLCK/p‑MLC signaling pathway

Ganxian Wang, Guangcheng Sun, Yi Wang, Pei Yu, Xue Wang, Birong Zhou, Huaqing Zhu
Pages: 107-114
Published online on: 30 October 2018

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Article Open Access

Effect of microRNA‑370 on coronary atherosclerosis and its underlying mechanism

Xinge Shi, Xin Chen
Pages: 115-122
Published online on: 13 November 2018

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Article Open Access

Biological effects different diameters of Tussah silk fibroin nanofibers on olfactory ensheathing cells

Peng Wu, Peng Zhang, Hanjiang Zheng, Baoqi Zuo, Xiaofeng Duan, Junjun Chen, Xinhong Wang, Yixin Shen
Pages: 123-130
Published online on: 06 November 2018

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Article Open Access

Establishment of loop‑mediated isothermal amplification for rapid detection of Pseudomonas aeruginosa

Chao Li, Yaoqiang Shi, Guangying Yang, Xue‑Shan Xia, Xiaoqin Mao, Yue Fang, A‑Mei Zhang, Yuzhu Song
Pages: 131-136
Published online on: 31 October 2018

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Article Open Access

Complications of cataract surgery in Wistar rats undergoing treatment with tamsulosin

Raluca Maria Popescu, Ciprian Ober, Bogdan Sevastre, Marian Taulescu, Mihai Negru, Iulia Melega, Sidonia Bogdan, Cristina Nicula, Ioan Coman
Pages: 137-146
Published online on: 31 October 2018

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Article Open Access

Soluble triggering receptor expressed on myeloid cells‑1 as a useful biomarker for diagnosing ventilator‑associated pneumonia after congenital cardiac surgery in children

Chunxiang Li, Limin Zhu, Xiaolei Gong, Zhuoming Xu, Yujie Liu, Mingjie Zhang, Qing Cao
Pages: 147-152
Published online on: 31 October 2018

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Article Open Access

Expression of ADAMTS‑1 mRNA in myocardium of viral heart disease mice and its clinical significance

Hongmei Li, Yanchun Zhou, Wei Song, Jianxiu Li, Jingtao Xu
Pages: 153-158
Published online on: 25 October 2018

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Article Open Access

Risk factors and prognosis of acute respiratory distress syndrome following abdominal surgery

Bingzheng Xu, Yangli Ge, Yangzhen Lu, Qianqian Chen, Hongjin Zhang
Pages: 159-164
Published online on: 05 November 2018

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Article Open Access

Increased expression of claudin‑12 promotes the metastatic phenotype of human bronchial epithelial cells and is associated with poor prognosis in lung squamous cell carcinoma

Lemeng Sun, Liangshu Feng, Jiuwei Cui
Pages: 165-174
Published online on: 13 November 2018

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Article Open Access

miRNA-101 promotes chondrogenic differentiation in rat bone marrow mesenchymal stem cells

Feng Gao, Chuangang Peng, Changjun Zheng, Shanyong Zhang, Minfei Wu
Pages: 175-180
Published online on: 12 November 2018

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Article Open Access

Expression variations and clinical significance of MMP-1, MMP-2 and inflammatory factors in serum of patients with deep venous thrombosis of lower extremity

Tangshan Zhang, Qiang Li, Lijuan Wang, Guangxin Li
Pages: 181-186
Published online on: 02 November 2018

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Article Open Access

Protective effects of dexmedetomidine on lung in rats with one‑lung ventilation

Juntao Wang, Xuanlong Yi, Lili Jiang, He Dong, Wei Feng, Shuntao Wang, Chunqin Chu
Pages: 187-192
Published online on: 09 November 2018

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Article Open Access

Experimental animal study on BMP-3 expression in periodontal tissues in the process of orthodontic tooth movement

Yang Gao, Ming Zhang, Xia Tian, Meng Wang, Fan Zhang
Pages: 193-198
Published online on: 09 November 2018

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Article Open Access

PDE5 inhibitor protects the mitochondrial function of hypoxic myocardial cells

Haiyan Jia, Zhen Guo, Yanfen Yao
Pages: 199-204
Published online on: 09 November 2018

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Article Open Access

Elevated methylation of cyclin dependent kinase inhibitor 2B contributes to the risk of coronary heart disease in women

Xiaomin Chen, Danjie Jiang, Limin Xu, Liyuan Han, Haochang Hu, Yi Huang, Deyi Lu, Huihui Ji, Bin Li, Yong Yang, Cong Zhou, Xuting Xu, Nan Wu, Xiaofeng Xu, Yan Xu, Yusheng Shen, Jiyi Li, Shiwei Duan
Pages: 205-213
Published online on: 02 November 2018

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Article Open Access

Micro‑scale assessment of the postoperative effect of anterior cruciate ligament reconstruction preclinical study using a 7.1T micro‑magnetic resonance imaging

Fang Chai, Fang Wan, Jia Jiang, Shiyi Chen
Pages: 214-220
Published online on: 19 April 2018

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Article Open Access

microRNA‑200a functions as a tumor suppressor by targeting FOXA1 in glioma

Xiaofeng Chen, Kun Liu, Ping Yang, Weiping Kuang, Hongxing Huang, Ewen Tu, Bo Li, Yong Zhu, Bin Zhou, Lin Yan
Pages: 221-229
Published online on: 29 October 2018

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Article Open Access

Berberine protects myocardial cells against anoxia‑reoxygenation injury via p38 MAPK‑mediated NF‑κB signaling pathways

Yu Zhao, Xuefeng Tian, Gengfeng Liu, Kuijing Wang, Yuanyuan Xie, Yuxuan Qiu
Pages: 230-236
Published online on: 09 November 2018

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Article Open Access

Coexpression modules constructed by weighted gene co‑expression network analysis indicate ubiquitin‑mediated proteolysis as a potential biomarker of uveal melanoma

Meng Yang, Qi Wan, Xiang Hu, Haitao Yin, Dawei Hao, Chengjun Wu, Jianmin Li
Pages: 237-243
Published online on: 09 November 2018

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Article

Prognostic biological factors of radiation pneumonitis after stereotactic body radiation therapy combined with pulmonary perfusion imaging

Leiming Guo, Gaofeng Ding, Wencai Xu, Yufei Lu, Hong Ge, Yue Jiang, Xijuan Chen, Yin Li
Pages: 244-250
Published online on: 06 November 2018

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Article Open Access

Rhynchophylline attenuates allergic bronchial asthma by inhibiting transforming growth factor‑β1‑mediated Smad and mitogen‑activated protein kinase signaling transductions in vivo and in vitro

Meng Wang, Hui Li, Yaxin Zhao, Chuanfeng Lv, Guanghua Zhou
Pages: 251-259
Published online on: 31 October 2018

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Article Open Access

miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene Retraction in /10.3892/etm.2025.13013

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Pages: 260-272
Published online on: 30 October 2018

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Article Open Access

Glucose affects cell viability, migration, angiogenesis and cellular adhesion of human retinal capillary endothelial cells via SPARC

Yang Fu, Min Tang, Xiaoqiong Xiang, Kun Liu, Xun Xu
Pages: 273-283
Published online on: 14 November 2018

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Article Open Access

MicroRNA‑122 inhibits epithelial‑mesenchymal transition of hepatic stellate cells induced by the TGF‑β1/Smad signaling pathway

Bianqiao Cheng, Qi Zhu, Weiguo Lin, Lihui Wang
Pages: 284-290
Published online on: 13 November 2018

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Article Open Access

lncRNA MEG3 is downregulated in ankylosing spondylitis and associated with disease activity, hospitalization time and disease duration

Wei Liu, Lili Huang, Cuiying Zhang, Zuozhong Liu
Pages: 291-297
Published online on: 02 November 2018

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Article Open Access

Identification of candidate target genes for endometrial cancer, such as ANO1, using weighted gene co‑expression network analysis

Fangzhen Wang, Bo Wang, Junbei Long, Fangmin Wang, Ping Wu
Pages: 298-306
Published online on: 13 November 2018

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Article Open Access

Combined effect of propranolol, vincristine and bevacizumab on HUVECs and BJ cells

Mădălina Bota, Eva Fischer‑Fodor, Ovidiu‑Vasile Bochiș, Mihai Cenariu, Gheorghe Popa, Cristina Lucia Blag, Alexandru Tătaru
Pages: 307-315
Published online on: 02 November 2018

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Article Open Access

Biological effects of autophagy in mice with sepsis‑induced acute kidney injury

Yu Wu, Ling Wang, Lei Meng, Guang‑Ke Cao, Yu‑Liang Zhao, Yang Zhang
Pages: 316-322
Published online on: 30 October 2018

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Article Open Access

International normalized ratio on admission predicts the 90‑day mortality of critically ill patients undergoing endarterectomy

Lang‑Ping Tan, Yi‑Biao Ye, Yue Zhu, Zhi‑Long Gu, Qin‑Gui Chen, Miao‑Yun Long
Pages: 323-331
Published online on: 06 November 2018

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Article Open Access

Effect of rosuvastatin on vascular endothelial functions and inflammatory factors of patients with type 2 diabetes mellitus and coronary heart disease

Gang Ma, Shuting Bi
Pages: 332-336
Published online on: 02 November 2018

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Article Open Access

Functional posterior communicating artery of patients with posterior circulation ischemia using phase contrast magnetic resonance angiography

Wei Zhou, Minru Lu, Jun Li, Feng Chen, Qiugen Hu, Shaomin Yang
Pages: 337-343
Published online on: 29 October 2018

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Article Open Access

Correlation of clinical features with hs‑CRP in TRD patients

Juan Qiao, Deqin Geng, Liju Qian, Xianghua Zhu, Houfeng Zhao
Pages: 344-348
Published online on: 01 November 2018

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Article Open Access

Arterial blood gas and acid‑base balance in patients with pregnancy‑induced hypertension syndrome

Yali Cao, Meichun Wang, Yuchao Yuan, Cong Li, Qinglin Bai, Min Li
Pages: 349-353
Published online on: 24 October 2018

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Article Open Access

Preoperative intravenous flurbiprofen reduces postoperative pain and inflammatory cytokines in elderly patients after hip arthroplasty

Zhi-Jun Zhou, Jian Tang, Wei-Hua Li, Wei-Dong Tao
Pages: 354-358
Published online on: 31 October 2018

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Article Open Access

Long‑term graft patency after coronary artery bypass grafting: Effects of surgical technique

Grigore Tinica, Raluca Ozana Chistol, Diana Bulgaru Iliescu, Cristina Furnica
Pages: 359-367
Published online on: 06 November 2018

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Article Open Access

Correlation of the severity of chronic kidney disease with serum inflammation, osteoporosis and vitamin D deficiency

Cewen Liu, Hui Li
Pages: 368-372
Published online on: 01 November 2018

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Article Open Access

Diagnostic value of urinary RBP, ALB and AQP2 in neonatal hydronephrosis and the relationship with expression of MCP-1 in the prenatal maternal peripheral blood

Ma Zhi, Yanan Zhang, Lixia Liu, Huizhi Wang
Pages: 373-377
Published online on: 01 November 2018

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Article Open Access

Protective effect of Qishen Yiqi dropping pills on the myocardium of rats with chronic heart failure

Yinghong Lu, Dan Wang, Xiaoli Yuan, Mengchao Wang, Zhihui Li, Xiaoqing Bao, Chengjia Zhang, Haiyun Jing
Pages: 378-382
Published online on: 12 November 2018

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Article Open Access

Changes in TNF-α, IL-6, IL-10 and VEGF in rats with ARDS and the effects of dexamethasone

Mengting Qin, Zhongpeng Qiu
Pages: 383-387
Published online on: 05 November 2018

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Article Open Access

miR-138 expression in oral herpes simplex and its effect on ICP0

Xiao Yan, Jing Sun, Kuifeng Yuan
Pages: 388-392
Published online on: 01 November 2018

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Article Open Access

Astragaloside Ⅳ combating liver cirrhosis through the PI3K/Akt/mTOR signaling pathway

Rendong Wei, Haidong Liu, Ru Chen, Yunjian Sheng, Tao Liu
Pages: 393-397
Published online on: 13 November 2018

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Article Open Access

Osteogenic efficiency in vivo of scaffolding material of prefabricated vascularization

Xiaorui Jiang, Huiying Yang, Botao Huang, Guodong Lin, Kai Wang, Yongchun Meng, Chunyu Xue
Pages: 398-402
Published online on: 01 November 2018

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Article Open Access

Changes of body immunity and inflammatory response in HIV/HCV co-infected patients

Yuhong Dong, Xiaoli Zhi, Guo Lei
Pages: 403-407
Published online on: 07 November 2018

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Article Open Access

Changes in sICAM-1 and GM-CSF levels in skin tissue fluid and expression of IL-6, IL-17 and TNF-α in blood of patients with vitiligo

Xuesong Yang, Lingyi Yan, Da Ha, Lina Qu, Ling Liu, Yu Tao
Pages: 408-412
Published online on: 07 November 2018

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Article Open Access

Gene mutation analysis and genetic counseling for patients with non‑syndromic hearing loss in Linyi region

Huafeng Li, Jigang Qiu, Jinping Zhu, Yuqiang Huang
Pages: 413-417
Published online on: 05 November 2018

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Article Open Access

Correlation analysis between 25-hydroxyvitamin D3, vitamin B12 and vitamin C and endothelial function of patients with CHD

Xiaoming Qin, Lei Qin, Jiachen Luo, Baoxin Liu, Jinlong Zhao, Hongqiang Li, Yidong Wei
Pages: 418-422
Published online on: 08 November 2018

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Article Open Access

CTX‑II and YKL‑40 in early diagnosis and treatment evaluation of osteoarthritis

Pengkun Wang, Jinlong Song, Dongyang Qian
Pages: 423-431
Published online on: 12 November 2018

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Case Report Open Access

Treatment of severe acute pancreatitis via endoscopic pancreatic stenting and nasopancreatic drainage: Case reports

Zuozheng Wang, Qi Wang, Jianjun Song, Weijie Yao, Peng Lei, Chaofeng Tang, Peng Yuan, Junzhi Leng
Pages: 432-436
Published online on: 12 November 2018

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Article

Fluid resuscitation via the rectum ameliorates hemodynamic disorders through adjusting aquaporin expression in an experimental severe acute pancreatitis model

Rongli Xie, Jinlong Wang, Yi Yao, Mengzhi Qi, Shunwei Huang, Zhifeng Zhao, Ying Chen, Zhitao Yang, Huiqiu Sheng, Jian Fei, Enqiang Mao, Erzhen Chen
Pages: 437-443
Published online on: 06 November 2018

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Article

Bone marrow stromal cells improved functional recovery in spinal cord injury rats partly via the Toll‑like receptor‑4/nuclear factor‑κB signaling pathway

Shi Bai, Hao Zhou, Lijuan Wu
Pages: 444-448
Published online on: 31 October 2018

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Case Report

Two successive cases of fetal harlequin ichthyosis: A case report

Qianhong Liang, Fu Xiong, Xuankun Liang, Dongming Zheng, Shuguang Su, Yunjie Wen, Xiaodan Wang
Pages: 449-452
Published online on: 02 November 2018

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Article

Risk factors for hypertensive retinopathy in a Chinese population with hypertension: The Beijing Eye study

Youjing Zhang, Lu Zhao, Hongyang Li, Yanling Wang
Pages: 453-458
Published online on: 14 November 2018

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Article

Surfactant protein A induces the pathogenesis of renal fibrosis through binding to calreticulin

Jian Hao, Xin Zhao, Weimin Yu, Xiaoguang Huang, Yirong Huang
Pages: 459-464
Published online on: 02 November 2018

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Article

Therapeutic effect of combined hyperbaric oxygen and radiation therapy for single brain metastasis and its influence on osteopontin and MMP‑9

Jing Tao, Zhaoyu Gao, Rui Huang, Hong Li
Pages: 465-471
Published online on: 06 November 2018

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Effects of propofol on human cholangiocarcinoma and the associated mechanisms 

Zhuo Zhang, Mingcui Zang, Shuang Wang, Chunli Wang
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Published online on: 31 October 2018

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Carvedilol alleviates diabetic cardiomyopathy in diabetic rats

Wencheng Zheng, Ding Li, Xiang Gao, Wenqian Zhang, Barry O. Robinson
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Published online on: 12 November 2018

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Saikosaponin D inhibits proliferation of human osteosarcoma cells via the p53 signaling pathway

Lin Zhao, Jing Li, Zhi‑Bo Sun, Chen Sun, Zhi‑Hong Yu, Xiao Guo
Pages: 488-494
Published online on: 14 November 2018

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Effects of astigmatic keratotomy combined with scleral tunnel incisions for the treatment of high astigmatism after penetrating keratoplasty

Zheng‑Yu Gu, Min‑Jie Ye, Kang‑Kang Ji, Rong‑Feng Liao
Pages: 495-501
Published online on: 14 November 2018

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Variations in ductus arteriosus Doppler parameters in different sonographic views during the second half of gestation

Zhongshan Gou, Jie Zhang, Xinxin Yan, Zhenqi Wang, Shaolei Li, Xuedong Deng
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A novel frameshift PKD1 mutation in a Chinese patient with autosomal dominant polycystic kidney disease and azoospermia: A case report

Jialin Meng, Yuchen Xu, Xufeng Shen, Chaozhao Liang
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Published online on: 09 November 2018

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Comparative study of computed tomography of normal and lymphoid follicular hyperplasia thymus in myasthenia gravis patients

Hui Zhang, Peng Zhang, Tie‑Lian Yu
Pages: 512-518
Published online on: 09 November 2018

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Protective effects of astragaloside IV on IL‑8‑treated diaphragmatic muscle cells

Li Wang, Wei Gu, Ying Shi, Yubao Chen, Yan Tan
Pages: 519-524
Published online on: 08 November 2018

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Combined phacoemulsification, 23‑gauge pars plana vitrectomy with internal limiting membrane peeling and gas tamponade for patients with coexisting idiopathic macular hole and age‑associated cataract

Qingmin Ma, Fang Fan, Zhihua Zhao, Zhiyang Jia
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Published online on: 13 November 2018

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A Bayesian network analysis on comparative efficacy of treatment strategies for dialysis patients with secondary hyperparathyroidism

Huizhen Ye, Peiyi Ye, Zhe Zhang, Aizhen Hou, Zijie Liang, Yaozhong Kong
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Effect of Azadirachta indica flower extract on functional recovery of sciatic nerve crush injury in rat models of DM

Napatr Sriraksa, Ratchaniporn Kongsui, Sitthisak Thongrong, Acharaporn Duangjai, Thaneeya Hawiset
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Eriodictyol protects H9c2 cardiomyocytes against the injury induced by hypoxia/reoxygenation by improving the dysfunction of mitochondria

Yanli Xie, Rongwei Ji, Minghui Han
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[Corrigendum] Combined antitumor effects of P‑5m octapeptide and 5‑fluorouracil on a murine model of H22 hepatoma ascites

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Normal‑tension glaucoma: Pathogenesis and genetics (Review)

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Desquamative interstitial pneumonia: Risk factors, laboratory and bronchoalveolar lavage findings, radiological and histopathological examination, clinical features, treatment and prognosis (Review)

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In vitro predegeneration of peripheral nerve; the effect of predegeneration period on rat Schwann cell cultures

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Abnormalities of diffusional kurtosis imaging and regional homogeneity in idiopathic generalized epilepsy with generalized tonic‑clonic seizures

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Loss of atypical chemokine receptor 4 facilitates C‑C motif chemokine ligand 21‑mediated tumor growth and invasion in nasopharyngeal carcinoma

Yunhe Ju, Chuanzheng Sun, Xiaoli Wang
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Differential expression of long non‑coding RNA and mRNA in children with Henoch‑Schönlein purpura nephritis

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Restoration of miRNA‑148a in pancreatic cancer reduces invasion and metastasis by inhibiting the Wnt/β‑catenin signaling pathway via downregulating maternally expressed gene‑3

Yunpeng Sun, Qiandong Zhu, Mengtao Zhou, Wenjun Yang, Hongqi Shi, Yunfeng Shan, Qiyu Zhang, Fuxiang Yu
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Differential expression of serum proteins in multiple myeloma

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Correlation analysis of levels of inflammatory cytokines and nitric oxide in peripheral blood with urine proteins and renal function in patients with gestational hypertension

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Nischarin attenuates apoptosis induced by oxidative stress in PC12 cells

Zhanpeng Guo, Yajiang Yuan, Yue Guo, Hongyu Wang, Changwei Song, Mina Huang
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Hydroxytyrosol protects against myocardial ischemia reperfusion injury by inhibiting mitochondrial permeability transition pore opening

Jiaxin Miao, Zijun Huang, Shuang Liu, Xuying Li, Pengyu Jia, Yuxuan Guo, Nan Wu, Dalin Jia
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Stimulation of tolerogenic dendritic cells using dexamethasone and 1,25‑dihydroxyvitamin D3 represses autologous T cell activation and chondrocyte inflammation

Gaoyuan Wang, Junqiang Zhang, Yuan Fang, Wei Cao, Bin Xu, Xiaoyu Chen
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Bone marrow adipose amount influences vertebral bone strength

Mo Zhu, Guangyu Hao, Jianming Xing, Su Hu, Dechun Geng, Wen Zhang, Qianqian Wang, Chunhong Hu, Ximing Wang
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Application of different anesthetic methods in coronary artery bypass grafting and the effect on postoperative outcome

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Association of the proliferation of lung fibroblasts with the ERK1/2 signaling pathway in neonatal rats with hyperoxia‑induced lung fibrosis

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Expression of microRNA‑21 in osteoporotic patients and its involvement in the regulation of osteogenic differentiation

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The effect of aerobic dance intervention on brain spontaneous activity in older adults with mild cognitive impairment: A resting‑state functional MRI study

Ming Qi, Yi Zhu, Ling Zhang, Ting Wu, Jie Wang
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TBX2 overexpression promotes proliferation and invasion through epithelial‑mesenchymal transition and ERK signaling pathway

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Long non‑coding RNA XIST serves an oncogenic role in osteosarcoma by sponging miR‑137

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Mesothelin‑targeted second generation CAR‑T cells inhibit growth of mesothelin‑expressing tumors in vivo

Lin Ye, Yuqing Lou, Liming Lu, Xiaohong Fan
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Effect of different charges of modified electroconvulsive seizure on the cognitive behavior in stressed rats: Effects of GluR1 phosphorylation and CaMKIIα activity

Fan Zhang, Guihua Huang, Xianlin Zhu
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Relationship between serum IL‑1β and insomnia and liver depression in patients with perimenopausal non‑organic sleep disorder

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Comparative evaluation of the osteogenic capacity of human mesenchymal stem cells from bone marrow and umbilical cord tissue

Qian Wang, Gang Zhao, Zijun Xing, Juming Zhan, Jie Ma
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miR‑96 promotes collagen deposition in keloids by targeting Smad7

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Expression and role of EGFR, cyclin D1 and KRAS in laryngocarcinoma tissues

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Correlation of insulin‑resistance with blood fat and glucose in elder patients after surgery for hepatic carcinoma

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Curcumin improves perfusion recovery in experimental peripheral arterial disease by upregulating microRNA‑93 expression

Jinfeng Zhang, Qiongtao Wang, Guotao Rao, Junying Qiu, Ronghua He
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Long non‑coding RNA XIST promotes osteoporosis through inhibiting bone marrow mesenchymal stem cell differentiation

Xi Chen, Lei Yang, Dawei Ge, Weiwei Wang, Zhaowei Yin, Junwei Yan, Xiaojian Cao, Chunzhi Jiang, Shengnai Zheng, Bin Liang
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Effects of febuxostat on serum cytokines IL‑1, IL‑4, IL‑6, IL‑8, TNF‑α and COX‑2

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ERp29 downregulation enhances lung adenocarcinoma cell chemosensitivity to gemcitabine by upregulating HSP27 phosphorylation

Wu Ye, Zhijun Li, Tingyu Tang, Jianzong Du, Xiaoxi Zhou, Haiyan Wu, Xuefang Li, Guangyue Qin
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Escherichia coli O101‑induced diarrhea develops gut microbial dysbiosis in rats

Xiangwan Sun, Ying Gao, Xin Wang, Ge Hu, Yun Wang, Bo Feng, Yanxin Hu, Xiang Mu, Ying Zhang, Hong Dong
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ROS induces epithelial‑mesenchymal transition via the TGF‑β1/PI3K/Akt/mTOR pathway in diabetic nephropathy

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Effects of altitude changes on mild‑to‑moderate closed‑head injury in rats following acute high‑altitude exposure

Hao Wang, Xiyan Zhu, Hongyi Xiang, Zhikang Liao, Mou Gao, Yetao Luo, Pengfei Wu, Yihua Zhang, Mingliang Ren, Hui Zhao, Minhui Xu
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Long non‑coding RNA ZEB1‑AS1 indicates poor prognosis and promotes melanoma progression through targeting miR‑1224‑5p

Qiong Wang, Ruirui Zhang, Dandan Liu
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Published online on: 23 November 2018

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Combined effects of hyperphosphatemia and hyperglycemia on the calcification of cultured human aortic smooth muscle cells

Ping Wang, Ping Zhou, Wangshan Chen, Dan Peng
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Post‑operative outcomes associated with Boston type 1 keratoprosthesis implantation in Northeast China

Minghong Gao, Yingxin Chen, Jing Wang, Cuiyu Wang
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Percutaneous transforaminal endoscopic discectomy in the treatment of senior patients with lumbar degenerative disc disease

Jiayue Bai, Wei Zhang, Xiangzhou Liu, Jinghang Cheng, Xianzheng Wang, Wenyuan Ding, Yong Shen
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Clinical observation of orbital IgG4‑related diseases

Na Wu, Feng Yuan Sun
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Clinical outcomes of patients with primary malignant bone and soft tissue tumor aged 65 years or older

Kazuhiko Hashimoto, Shunji Nishimura, Yukiko Hara, Naohiro Oka, Hiroki Tanaka, Shunki Iemura, Masao Akagi
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lncRNA DGCR5 acts as a tumor suppressor in papillary thyroid carcinoma via sequestering miR‑2861

Fukun Chen, Shuting Yin, Jialun Zhu, Pengjie Liu, Chuanzhou Yang, Zhiping Feng, Zhiyong Deng
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Efficacy of panretinal laser in ischemic central retinal vein occlusion: A systematic review

Chengfang Li, Rongrong Wang, Guojun Liu, Zhen Ge, Dongdong Jin, Yao Ma, Guixiang Liu
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Wogonin affects proliferation and the energy metabolism of SGC‑7901 and A549 cells

Shu‑Jing Wang, Jian‑Kai Zhao, Shuang Ren, Wei‑Wei Sun, Wen‑Jun Zhang, Jia‑Ning Zhang
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MicroRNA‑432 is downregulated in osteosarcoma and inhibits cell proliferation and invasion by directly targeting metastasis‑associated in colon cancer‑1 Retraction in /10.3892/etm.2022.11402

Dengkun Lv, Zhen Zhen, Defa Huang
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Thalidomide decreases high glucose‑induced extracellular matrix protein synthesis in mesangial cells via the AMPK pathway

Hong‑Xia Zhang, Jie Yuan, Ya‑Feng Li, Rong‑Shan Li
Pages: 927-934
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Morphine and ketamine treatment suppress the differentiation of T helper cells of patients with colorectal cancer in vitro

Min Hou, Naibao Zhou, Hao Li, Baosheng Wang, Xiuqin Wang, Xingwu Wang, Tao Jiang, Kaiguo Wang, Fushan Xue
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Tranexamic acid is beneficial for reducing perioperative blood loss in transurethral resection of the prostate

Qian‑Qian Meng, Ning Pan, Jun‑Yu Xiong, Na Liu
Pages: 943-947
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Validity of venous phase delay assessment in balloon occlusion test of internal carotid artery

Zhu Chen, Li‑Nan Hu, Hui Zhu, En‑Hua Xiao
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Ginsenoside Rg3 promotes the antitumor activity of gefitinib in lung cancer cell lines

Yuemei Dai, Wenran Wang, Qingchao Sun, Jiazina Tuohayi
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Atorvastatin improves left ventricular remodeling and cardiac function in rats with congestive heart failure by inhibiting RhoA/Rho kinase‑mediated endothelial nitric oxide synthase

Liping An, Shoukuan An, Zhuowen Jia, Huan Wang, Zhaoying Yang, Chaoxin Xu, Xiane Teng, Jipeng Wang, Xiaodong Liu, Qidong Cao, Sha Wang
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GOLD stage predicts thoracic aortic calcifications in patients with COPD

Bertram J. Jobst, Michael Owsijewitsch, Hans‑Ulrich Kauczor, Jürgen Biederer, Sebastian Ley, Nikolaus Becker, Annette Kopp‑Schneider, Stefan Delorme, Claus Peter Heussel, Michael Puderbach, Mark O. Wielpütz, Julia Ley‑Zaporozhan
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Published online on: 30 November 2018

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Published online on: 05 December 2025

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Case Report

Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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Case Report

A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Article Open Access

Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model

Omer Cennet, Akbar Hajiyev, Burcin Şener, Filiz Akbiyik, Cenk Sökmensüer, Osman Abbasoglu
Article Number: 40
Published online on: 01 December 2025

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The influence of fetal sex on preterm birth risk in gestational diabetes mellitus: A retrospective cohort study

Xuemei Sun, Min Yang, Lingling Wan, Hua Zhong
Article Number: 39
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] circRNA_PTPRA functions as a sponge of miR‑582‑3p to regulate hepatocellular carcinoma cell proliferation, migration, invasion and apoptosis

Yanlin Jin, Yi Zhang, Xiaoming Luo
Article Number: 38
Published online on: 01 December 2025

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Article Open Access

Effects of small incision lenticule extraction and femtosecond laser‑assisted in situ keratomileusis on choroidal thickness and blood flow density in patients with myopia

Shirui Yang, Tiantian Qian, Min Tang, Jing Zhang, Jie Hou, Yahui Dong, Yulin Lei
Article Number: 37
Published online on: 01 December 2025

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Article Open Access

Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

Yanru Guo, Zhi Li, Yiqun Zhang, Zhijuan Pan, Jiajia Sun, Ying Zhang, Shuting Chang, Zhiping Guo
Article Number: 36
Published online on: 01 December 2025

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Article Open Access

Patients with sickle cell disease and asthma have a higher risk for acute chest syndrome: A systematic review and meta‑analysis of observational studies

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 35
Published online on: 28 November 2025

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Article Open Access

Early enteral nutrition may reduce the incidence of refeeding syndrome for patients with severe corona virus disease 2019 and high nutritional risk

Liuniu Xiao, Xiao Ran, Shusheng Li
Article Number: 34
Published online on: 28 November 2025

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Outcomes of anti‑VEGF therapy compared with conventional interventions in diabetic retinopathy management

Yong Guo, Rui Yang, Yan Li, Chenjun Guo, Houcheng Liang
Article Number: 33
Published online on: 28 November 2025

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Article Open Access

Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
Article Number: 32
Published online on: 28 November 2025

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Article Open Access

Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Article Open Access

Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
Article Number: 30
Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
Article Number: 29
Published online on: 24 November 2025

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