Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
January-2019 Volume 17 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-2019 Volume 17 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Long‑term graft patency after coronary artery bypass grafting: Effects of surgical technique

  • Authors:
    • Grigore Tinica
    • Raluca Ozana Chistol
    • Diana Bulgaru Iliescu
    • Cristina Furnica
  • View Affiliations / Copyright

    Affiliations: Department of Cardiovascular Surgery, ‘Prof. Dr. George I.M. Georgescu’ Cardiovascular Diseases Institute, 700503 Iasi, Romania, Department of Medical Imaging, ‘Prof. Dr. George I.M. Georgescu’ Cardiovascular Diseases Institute, 700503 Iasi, Romania, Discipline of Forensic Medicine, Medical Department III, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania, Institute of Forensic Medicine, 700455 Iasi, Romania
    Copyright: © Tinica et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 359-367
    |
    Published online on: November 6, 2018
       https://doi.org/10.3892/etm.2018.6929
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The aim of the current study was to identify surgical factors associated with long‑term patency of grafts used in coronary artery bypass grafting (CABG). The present study analyzed data from 127 patients who underwent CABG at our institute between 2000 and 2006 and presented for ambulatory examination and coronary computed tomography angiography evaluation of graft patency in 2016 (139.78±36.64 months post‑CABG). The 127 patients received 340 grafts (2.68 grafts/patient) and 399 distal anastomoses (3.14 anastomoses/patient), 220 (55.14%) with arterial grafts and 179 (44.86%) with saphenous vein grafts. Graft patency varied according to coronary territory, proximal anastomosis type (in situ graft, composite graft, graft anastomosed to the ascending aorta), Y anastomosis angle (47.21˚ for patent arterial grafts vs. 56˚ for occluded), and distal anastomosis angle (in sequential anastomoses irrespective to graft type, 48.60˚ for patent side‑to‑side anastomosis vs. 53.97˚ for occluded, 65.12˚ for patent end‑to‑side anastomosis vs. 90.80˚ for occluded; in single end‑to‑side anastomosis of arterial grafts, 39.46˚ for patent and 44.94˚ for occluded). A single end‑to‑side anastomosis angle 60˚ or greater was associated with a 5.149 occlusion odds ratio (OR) (P<0.001) for arterial grafts. Venous grafts were not sensitive to single end‑to‑side anastomosis angle. In conclusion, a small anastomosis angle for proximal Y and distal anastomoses is associated with a higher long‑term patency of the free graft. Radial artery grafts registered higher patency rates when anastomosed to the ascending aorta compared with composite grafting with the left internal thoracic artery, whereas in situ right internal thoracic artery (RITA) anastomosed to the right coronary territory is associated with a lower patency rate compared with free RITA used to revascularise the anterolateral or circumflex territory in composite grafting.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Eurostat-Cardiovascular diseases statistics. http://ec.europa.eu/eurostat/statistics-explained/index.php/Cardiovascular_diseases_statisticsAugust 31–2017

2 

Eurostat-Surgical operations and procedures statistics. http://ec.europa.eu/eurostat/statistics-explained/index.php/Surgical_operations_and_procedures_statisticsAugust 31–2017

3 

Authors/Task Force members, . Windecker S, Kolh P, Alfonso F, Collet JP, Cremer J, Falk V, Filippatos G, Hamm C, Head SJ, et al: 2014 ESC/EACTS guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J. 35:2541–2619. 2014. View Article : Google Scholar : PubMed/NCBI

4 

Coronary Revascularization Writing Group, . Patel FR, Dehmer GJ, Hirshfeld JW, Smith PK, Spertus JA; Technical Panel, ; Masoudi FA, Dehmer GJ, Patel MR, et al: ACCF/SCAI/STS/AATS/AHA/ASNC/HFSA/SCCT 2012 appropriate use criteria for coronary revascularization focused update: A report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, American Association for Thoracic Surgery, American Heart Association, American Society of Nuclear Cardiology, and the Society of Cardiovascular Computed Tomography. J Thorac Cardiovasc Surg. 143:780–803. 2012. View Article : Google Scholar : PubMed/NCBI

5 

Sabik JF III: Understanding saphenous vein graft patency. Circulation. 124:273–275. 2011. View Article : Google Scholar : PubMed/NCBI

6 

Tatoulis J, Buxton BF and Fuller JA: Patencies of 2127 arterial to coronary conduits over 15 years. Ann Thorac Surg. 77:93–101. 2004. View Article : Google Scholar : PubMed/NCBI

7 

Cameron AA, Green GE, Brogno DA and Thornton J: Internal thoracic artery grafts: 20-year clinical follow-up. J Am Coll Cardiol. 25:188–192. 1995. View Article : Google Scholar : PubMed/NCBI

8 

Taggart DP, D'Amico R and Altman DG: Effect of arterial revascularisation on survival: A systematic review of studies comparing bilateral and single internal mammary arteries. Lancet. 358:870–875. 2001. View Article : Google Scholar : PubMed/NCBI

9 

Georghiou GP, Vidne BA and Dunning J: Does the radial artery provide better long-term patency than the saphenous vein? Interact Cardiovasc Thorac Surg. 4:304–310. 2005. View Article : Google Scholar : PubMed/NCBI

10 

Petrovic I, Nezic D, Peric M, Milojevic P, Djokic O, Kosevic D, Tasic N, Djukanovic B and Otasevic P: Radial artery vs saphenous vein graft used as the second conduit for surgical myocardial revascularization: Long-term clinical follow-up. J Cardiothorac Surg. 10:1272015. View Article : Google Scholar : PubMed/NCBI

11 

Aydin S, Aydin S, Eren Nesimi M, Sahin I, Yilmaz M, Kalayci M and Gungor O: The cardiovascular system and the biochemistry of grafts used in heart surgery. Springerplus. 2:6122013. View Article : Google Scholar : PubMed/NCBI

12 

Buxton BF and Hayward PA: The art of arterial revascularization-total arterial revascularization in patients with triple vessel coronary artery disease. Ann Cardiothorac Surg. 2:543–551. 2013.PubMed/NCBI

13 

Drouin A, Noiseux N, Chartrand-Lefebvre C, Soulez G, Mansour S, Tremblay JA, Basile F, Prieto I and Stevens LM: Composite versus conventional coronary artery bypass grafting strategy for the anterolateral territory: Study protocol for a randomized controlled trial. Trials. 14:2702013. View Article : Google Scholar : PubMed/NCBI

14 

Ohira S, Doi K, Okawa K, Dohi M, Yamamoto T, Kawajiri H and Yaku H: Safety and efficacy of sequential left internal thoracic artery grafting to left circumflex area. Ann Thorac Surg. 102:766–773. 2016. View Article : Google Scholar : PubMed/NCBI

15 

Porto I, Gaudino M, De Maria GL, Di Vito L, Vergallo R, Bruno P, Bonalumi G, Prati F, Bolognese L, Crea F and Massetti M: Long-term morphofunctional remodeling of internal thoracic artery grafts: A frequency-domain optical coherence tomography study. Biomed Eng Online. 6:269–276. 2013.

16 

Ghista DN and Kabinejadian F: Coronary artery bypass grafting hemodynamics and anastomosis design: A biomedical engineering review. Biomed Eng Online. 12:1292013. View Article : Google Scholar : PubMed/NCBI

17 

Li H, Xie B, Gu C, Gao M, Zhang F, Wang J, Dai L and Yu Y: Distal end side-to-side anastomoses of sequential vein graft to small target coronary arteries improve intraoperative graft flow. BMC Cardiovasc Disord. 14:652014. View Article : Google Scholar : PubMed/NCBI

18 

Dion R, Glineur D, Derouck D, Verhelst R, Noirhomme P, El Khoury G, Degrave E and Hanet C: Long-term clinical and angiographic follow-up of sequential internal thoracic artery grafting. Eur J Cardiothorac Surg. 17:407–714. 2000. View Article : Google Scholar : PubMed/NCBI

19 

Calafiore AM, Contini M, Vitolla G, Di Mauro M, Mazzei V, Teodori G and Di Giammarco G: Bilateral internal thoracic artery grafting: Long-term clinical and angiographic results of in situ versus Y grafts. J Thorac Cardiovasc Surg. 120:990–996. 2000. View Article : Google Scholar : PubMed/NCBI

20 

Tatoulis J, Buxton BF and Fuller JA: Patencies of 2127 arterial to coronary conduits over 15 years. Ann Thorac Surg. 77:93–101. 2004. View Article : Google Scholar : PubMed/NCBI

21 

Fukui S, Fukuda H, Toda K, Yoshitatsu M, Funatsu T, Masai T and Miyamoto Y: Remodeling of the radial artery anastomosed to the internal thoracic artery as a composite straight graft. J Thorac Cardiovasc Surg. 134:1136–1142. 2007. View Article : Google Scholar : PubMed/NCBI

22 

Taggart DP: Current status of arterial grafts for coronary artery bypass grafting. Ann Cardiothorac Surg. 2:427–430. 2013.PubMed/NCBI

23 

Mukherjee D, Cheriyan J, Kourliouros A and Athanasiou T: Does the right internal thoracic artery or saphenous vein graft offer superior revascularization of the right coronary artery? Interact Cardiovasc Thorac Surg. 15:244–247. 2012. View Article : Google Scholar : PubMed/NCBI

24 

Jung SH, Song H, Choo SJ, Je HG, Chung CH, Kang JW and Lee JW: Comparison of radial artery patency according to proximal anastomosis site: Direct aorta to radial artery anastomosis is superior to radial artery composite grafting. J Thorac Cardiovasc Surg. 138:76–83. 2009. View Article : Google Scholar : PubMed/NCBI

25 

Song MH, Sato M and Ueda Y: Three-dimensional simulation of coronary artery bypass grafting with the use of computational fluid dynamics. Surg Today. 30:993–998. 2000. View Article : Google Scholar : PubMed/NCBI

26 

Staalsen NH, Ulrich M, Winther J, Pedersen EM, How T and Nygaard H: The anastomosis angle does change the flow fields at vascular end-to-side anastomoses in vivo. J Vasc Surg. 21:460–471. 1995. View Article : Google Scholar : PubMed/NCBI

27 

Frauenfelder T, Boutsianis E, Schertler T, Husmann L, Leschka S, Poulikakos D, Marincek B and Alkadhi H: Flow and wall shear stress in end-to-side and side-to-side anastomosis of venous coronary artery bypass grafts. Biomed Eng Online. 6:352007. View Article : Google Scholar : PubMed/NCBI

28 

Fei DY, Thomas JD and Rittgers SE: The effect of angle and flow rate upon hemodynamics in distal vascular graft anastomoses: A numerical model study. J Biomech Eng. 116:331–336. 1994. View Article : Google Scholar : PubMed/NCBI

29 

Sherwin SJ, Doorly DJ, Franke P and Peiró J: Unsteady near wall residence times and shear exposure in model distal arterial bypass grafts. Biorheology. 39:365–371. 2002.PubMed/NCBI

30 

Bonert M, Myers JG, Fremes S, Williams J and Ethier CR: A numerical study of blood flow in coronary artery bypass graft side-to-side anastomoses. Ann Biomed Eng. 30:599–611. 2002. View Article : Google Scholar : PubMed/NCBI

31 

Tremblay JA, Stevens LM, Chandonnet M, Soulez G, Basile F, Prieto I, Noiseux N and Chartrand-Lefebvre C: A morphometric 3D model of coronary artery bypass graft dysfunction with multidetector computed tomography. Clin Imaging. 39:1006–1011. 2015. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Tinica G, Chistol RO, Bulgaru Iliescu D and Furnica C: Long‑term graft patency after coronary artery bypass grafting: Effects of surgical technique. Exp Ther Med 17: 359-367, 2019.
APA
Tinica, G., Chistol, R.O., Bulgaru Iliescu, D., & Furnica, C. (2019). Long‑term graft patency after coronary artery bypass grafting: Effects of surgical technique. Experimental and Therapeutic Medicine, 17, 359-367. https://doi.org/10.3892/etm.2018.6929
MLA
Tinica, G., Chistol, R. O., Bulgaru Iliescu, D., Furnica, C."Long‑term graft patency after coronary artery bypass grafting: Effects of surgical technique". Experimental and Therapeutic Medicine 17.1 (2019): 359-367.
Chicago
Tinica, G., Chistol, R. O., Bulgaru Iliescu, D., Furnica, C."Long‑term graft patency after coronary artery bypass grafting: Effects of surgical technique". Experimental and Therapeutic Medicine 17, no. 1 (2019): 359-367. https://doi.org/10.3892/etm.2018.6929
Copy and paste a formatted citation
x
Spandidos Publications style
Tinica G, Chistol RO, Bulgaru Iliescu D and Furnica C: Long‑term graft patency after coronary artery bypass grafting: Effects of surgical technique. Exp Ther Med 17: 359-367, 2019.
APA
Tinica, G., Chistol, R.O., Bulgaru Iliescu, D., & Furnica, C. (2019). Long‑term graft patency after coronary artery bypass grafting: Effects of surgical technique. Experimental and Therapeutic Medicine, 17, 359-367. https://doi.org/10.3892/etm.2018.6929
MLA
Tinica, G., Chistol, R. O., Bulgaru Iliescu, D., Furnica, C."Long‑term graft patency after coronary artery bypass grafting: Effects of surgical technique". Experimental and Therapeutic Medicine 17.1 (2019): 359-367.
Chicago
Tinica, G., Chistol, R. O., Bulgaru Iliescu, D., Furnica, C."Long‑term graft patency after coronary artery bypass grafting: Effects of surgical technique". Experimental and Therapeutic Medicine 17, no. 1 (2019): 359-367. https://doi.org/10.3892/etm.2018.6929
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team