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Budd‑Chiari syndrome in Behcet's disease: A report of two cases

  • Authors:
    • Jun Zhou
    • Yu Wang
    • Yiming Liu
    • Hanjiang Zeng
    • Hanshi Xu
    • Fan Lian
  • View Affiliations / Copyright

    Affiliations: Department of Rheumatology and Clinical Immunology, The First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China, Department of Interventional Oncology, The First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China
    Copyright: © Zhou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1737-1741
    |
    Published online on: December 24, 2018
       https://doi.org/10.3892/etm.2018.7130
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Abstract

Budd‑Chiari syndrome (BCS) is a rare but severe venous form of Behcet's disease (BD) that is caused by the obstruction of the venous outflow tract that transports blood from hepatic veins into the inferior vena cava. In countries where BD is prevalent, including the Middle East and Far East, BCS awareness is important. In the present study, two cases of BCS are presented in two male Chinese patients with BD. The clinical characteristics, treatment and outcomes were recorded and compared with previous studies, and the features of BD‑BCS were summarized. The clinical characteristics of the two patients documented were similar. Each patient presented with insidious onset, abdominal symptoms and recurrent aphthous ulcers. Accurate diagnosis was delayed as other symptoms of BD were overlooked. Each patient responded well to TNF‑α inhibitor treatment in combination with cyclophosphamide (CYC). One patient with good compliance was removed from CYC and corticosteroid therapy. Unfortunately, the other patient with poor compliance faced a poor outcome. It was concluded that multiple vessel lesions in ≥2 sites are common in vasculo‑BD and that misdiagnosis may occur if other symptoms of BD are not noticed. BD‑BCS is associated with a high mortality rate, but appropriate treatment may result in a favorable outcome.
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Copy and paste a formatted citation
Spandidos Publications style
Zhou J, Wang Y, Liu Y, Zeng H, Xu H and Lian F: Budd‑Chiari syndrome in Behcet's disease: A report of two cases. Exp Ther Med 17: 1737-1741, 2019.
APA
Zhou, J., Wang, Y., Liu, Y., Zeng, H., Xu, H., & Lian, F. (2019). Budd‑Chiari syndrome in Behcet's disease: A report of two cases. Experimental and Therapeutic Medicine, 17, 1737-1741. https://doi.org/10.3892/etm.2018.7130
MLA
Zhou, J., Wang, Y., Liu, Y., Zeng, H., Xu, H., Lian, F."Budd‑Chiari syndrome in Behcet's disease: A report of two cases". Experimental and Therapeutic Medicine 17.3 (2019): 1737-1741.
Chicago
Zhou, J., Wang, Y., Liu, Y., Zeng, H., Xu, H., Lian, F."Budd‑Chiari syndrome in Behcet's disease: A report of two cases". Experimental and Therapeutic Medicine 17, no. 3 (2019): 1737-1741. https://doi.org/10.3892/etm.2018.7130
Copy and paste a formatted citation
x
Spandidos Publications style
Zhou J, Wang Y, Liu Y, Zeng H, Xu H and Lian F: Budd‑Chiari syndrome in Behcet's disease: A report of two cases. Exp Ther Med 17: 1737-1741, 2019.
APA
Zhou, J., Wang, Y., Liu, Y., Zeng, H., Xu, H., & Lian, F. (2019). Budd‑Chiari syndrome in Behcet's disease: A report of two cases. Experimental and Therapeutic Medicine, 17, 1737-1741. https://doi.org/10.3892/etm.2018.7130
MLA
Zhou, J., Wang, Y., Liu, Y., Zeng, H., Xu, H., Lian, F."Budd‑Chiari syndrome in Behcet's disease: A report of two cases". Experimental and Therapeutic Medicine 17.3 (2019): 1737-1741.
Chicago
Zhou, J., Wang, Y., Liu, Y., Zeng, H., Xu, H., Lian, F."Budd‑Chiari syndrome in Behcet's disease: A report of two cases". Experimental and Therapeutic Medicine 17, no. 3 (2019): 1737-1741. https://doi.org/10.3892/etm.2018.7130
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