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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-2019 Volume 17 Issue 3

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Article Open Access

Clinical effects of lentinan combined with budesonide inhalation in treating acute exacerbation of chronic obstructive pulmonary disease under mechanical ventilation

Jian Sun, Gang Zhao
Pages: 1503-1508
Published online on: 03 January 2019

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Article Open Access

MicroRNA‑375 inhibits esophageal squamous cell carcinoma proliferation through direct targeting of SP1 Retraction in /10.3892/etm.2025.12990

Hui Xu, Jialong Jiang, Jingjun Zhang, Liang Cheng, Song Pan, Yuanhai Li
Pages: 1509-1516
Published online on: 17 December 2018

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Article Open Access

Effect of oxaliplatin combined with 5-fluorouracil on treatment efficacy of radiotherapy in the treatment of elderly patients with rectal cancer

Jinfen Xu, Xia Li, Xinming Lv
Pages: 1517-1522
Published online on: 20 December 2018

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Article Open Access

Allicin suppresses the migration and invasion in cervical cancer cells mainly by inhibiting NRF2 Retraction in /10.3892/etm.2024.12659

Qiumei Zhang, Dongmei Yang
Pages: 1523-1528
Published online on: 17 December 2018

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Article Open Access

Elevated expression of microRNA‑378 in children with asthma aggravates airway remodeling by promoting the proliferation and apoptosis resistance of airway smooth muscle cells

Peng Li, Xufang Lang, Shungang Xia
Pages: 1529-1536
Published online on: 28 December 2018

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Article Open Access

miR‑181b‑5p promotes proliferation and inhibits apoptosis of hypertrophic scar fibroblasts through regulating the MEK/ERK/p21 pathway

Bo Liu, Zhe Guo, Weiming Gao
Pages: 1537-1544
Published online on: 07 January 2019

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Article Open Access

Effect of total glucosides of paeony on the changes of IL-4 and ICAM-1 levels in eczema mouse model serum

Meihua Zhou, Hongfeng Sui
Pages: 1545-1550
Published online on: 20 December 2018

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Article Open Access

Protective effect of Xin‑Ji‑Er‑Kang on cardiovascular remodeling in high salt‑induced hypertensive mice

Guangyao Huang, Pan Cheng, Ling Ding, Li Wang, Juan Hu, Yongxue Zhang, Guowei Cai, Meiling Chen, Aizong Shen, Shan Gao
Pages: 1551-1562
Published online on: 17 December 2018

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Article Open Access

Clinical efficacy evaluation of treatment of different degrees of retinal vein occlusion with ranibizumab combined with an argon ion laser

Dingding Wang, Xiaoyi Wang, Kunfang Wu, Juanjuan Wang, Guihua Xu, Zilin Chen
Pages: 1563-1568
Published online on: 21 December 2018

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Article Open Access

Resveratrol suppresses the invasion and migration of human gastric cancer cells via inhibition of MALAT1‑mediated epithelial‑to‑mesenchymal transition

Zhuying Yang, Qigui Xie, Zhanlei Chen, Haibin Ni, Liang Xia, Qiufeng Zhao, Zhiyun Chen, Peifeng Chen
Pages: 1569-1578
Published online on: 28 December 2018

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Article Open Access

microRNA‑196a attenuates ischemic brain injury in rats by directly targeting high mobility group A1

Junan Hu, Wei Shen
Pages: 1579-1586
Published online on: 04 January 2019

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Article Open Access

Expression of Notch-1 and nuclear factor-κB signal pathway in myocardial cells of coronary heart disease rats

Jiahui Zheng, Shufeng Zhang, Tingting Wang
Pages: 1587-1592
Published online on: 21 December 2018

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Article Open Access

3D culture enhances chemoresistance of ALL Jurkat cell line by increasing DDR1 expression

Jun Guo, Chunting Zhao, Ruyong Yao, Aihua Sui, Lingjie Sun, Xiaodan Liu, Shaoling Wu, Zhan Su, Tianlan Li, Shanshan Liu, Yan Gao, Jiaxiu Liu, Xianqi Feng, Wei Wang, Hongguo Zhao, Zhongguang Cui, Guanglun Li, Fanjun Meng
Pages: 1593-1600
Published online on: 04 January 2019

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Article Open Access

Experimental study of TNF‑α receptor gene transfection by ultrasound‑targeted microbubble destruction to treat collagen‑induced arthritis in rats in vivo

Liyun Wang, Xiaolan Tang, Xi Xiang, Yuanjiao Tang, Li Qiu
Pages: 1601-1610
Published online on: 07 January 2019

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Article Open Access

Cholinesterase inhibitors and memantine for Parkinson's disease dementia and Lewy body dementia: A meta‑analysis

Yan‑Hong Meng, Pan‑Pan Wang, Ya‑Xue Song, Jian‑Hua Wang
Pages: 1611-1624
Published online on: 24 December 2018

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Article Open Access

Effect of memantine combined with citalopram on cognition of BPSD and moderate Alzheimer's disease: A clinical trial

Tiantian Zhou, Jindong Wang, Cuiyu Xin, Lingli Kong, Chunxia Wang
Pages: 1625-1630
Published online on: 21 December 2018

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Article Open Access

Ropivacaine at different concentrations on intrapartum fever, IL‑6 and TNF‑α in parturient with epidural labor analgesia

Xianjin Zhou, Jiang Li, Shengqiong Deng, Zhendong Xu, Zhiqiang Liu
Pages: 1631-1636
Published online on: 20 December 2018

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Article Open Access

Downregulated MEG3 participates in rheumatoid arthritis via promoting proliferation of fibroblast‑like synoviocytes

Xin Lu, Jun Qian
Pages: 1637-1642
Published online on: 14 December 2018

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Article Open Access

Therapeutic effect of the epidermal growth factor on diabetic foot ulcer and the underlying mechanisms

Juanzi Zhang, Wenxian Hu, Qixian Diao, Zhaowei Wang, Jin Miao, Xiao Chen, Zhijun Xue
Pages: 1643-1648
Published online on: 24 December 2018

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Article Open Access

Adenovirus‑mediated herpes simplex virus thymidine kinase gene therapy combined with ganciclovir induces hepatoma cell apoptosis

Haitao Zhang, Ling Qin, Chaolu Li, Jianyi Jiang, Libo Sun, Xiaofei Zhao, Ning Li
Pages: 1649-1655
Published online on: 02 January 2019

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Article Open Access

Endovascular treatment of middle cerebral artery aneurysm with a (LVIS) device: Comparison of LVIS stent and non‑LVIS stent

Feiyu Chen, Xiaoyu Fang
Pages: 1656-1662
Published online on: 28 December 2018

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Article Open Access

Insulin‑like growth factor 2 promotes the adipogenesis of hemangioma‑derived stem cells

Kui Zhang, Fan Wang, Jun Huang, Yin Lou, Juan Xie, Honghong Li, Dongsheng Cao, Xueying Huang
Pages: 1663-1669
Published online on: 24 December 2018

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Article Open Access

Novel triazole analogs of apigenin‑7‑methyl ether exhibit potent antitumor activity against ovarian carcinoma cells via the induction of mitochondrial‑mediated apoptosis

Yuyan Qi, Zhaoxia Ding, Yushuang Yao, Dehua Ma, Feifei Ren, Hongjuan Yang, Aiping Chen
Pages: 1670-1676
Published online on: 28 December 2018

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Article Open Access

Butyrate stimulates hepatic gluconeogenesis in mouse primary hepatocytes

Xueying Ji, Feiye Zhou, Yuqing Zhang, Ruyuan Deng, Wan Xu, Mengyao Bai, Yun Liu, Li Shao, Xiao Wang, Libin Zhou
Pages: 1677-1687
Published online on: 28 December 2018

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Article Open Access

The activation of BDNF reduced inflammation in a spinal cord injury model by TrkB/p38 MAPK signaling

Jiedong Liang, Gui Deng, He Huang
Pages: 1688-1696
Published online on: 18 December 2018

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Article Open Access

Downregulation of miR‑183 inhibits the growth of PANC‑1 pancreatic cancer cells in vitro and in vivo, and increases chemosensitivity to 5‑fluorouracil and gemcitabine

Xiaoping Yang, Wei Wang, Xiong Zhang, Qi Zou, Lei Cai, Bo Yu
Pages: 1697-1705
Published online on: 19 December 2018

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Article Open Access

MicroRNA‑494‑3p protects rat cardiomyocytes against septic shock via PTEN

Peng Wu, Lingchen Kong, Jianzhong Li
Pages: 1706-1716
Published online on: 19 December 2018

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Article Open Access

Regulation of TGF‑β1 on PI3KC3 and its role in hypertension‑induced vascular injuries

Qin Zhang, Hu Liu, Jun Yang
Pages: 1717-1727
Published online on: 21 December 2018

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Article Open Access

Circular RNA hsa_circ_0014243 may serve as a diagnostic biomarker for essential hypertension

Shuying Zheng, Tianlun Gu, Xingjie Bao, Jihan Sun, Jinshun Zhao, Tao Zhang, Lina Zhang
Pages: 1728-1736
Published online on: 17 December 2018

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Article Open Access

Budd‑Chiari syndrome in Behcet's disease: A report of two cases

Jun Zhou, Yu Wang, Yiming Liu, Hanjiang Zeng, Hanshi Xu, Fan Lian
Pages: 1737-1741
Published online on: 24 December 2018

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Article Open Access

Epigallocatechin gallate inhibits cell growth and regulates miRNA expression in cervical carcinoma cell lines infected with different high‑risk human papillomavirus subtypes

Yu Zhu, Yongfang Huang, Mingmin Liu, Qi Yan, Wanhong Zhao, Ping Yang, Qin Gao, Juanjuan Wei, Wenxia Zhao, Lishan Ma
Pages: 1742-1748
Published online on: 24 December 2018

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Article Open Access

Analysis of detection results of thyroid function-related indexes in pregnant women and establishment of the reference interval

Qi Zhou, Yanli Zhang, Jianhua Zhou, Xiangrong Yang, Yuqiang Huang, Huafeng Li, Chunling Ma
Pages: 1749-1755
Published online on: 27 December 2018

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Article Open Access

Expression of Hcy and blood lipid levels in serum of CHD patients and analysis of risk factors for CHD

Weijing Liu, Tao Wang, Pengfei Sun, Yanju Zhou
Pages: 1756-1760
Published online on: 18 December 2018

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Article Open Access

Effect of testosterone on the expression of PPARγ mRNA in PCOS patients

Jinghe Cao, Gulijianati Maowulieti, Tao Yu
Pages: 1761-1765
Published online on: 14 December 2018

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Article Open Access

Inflammatory cytokines tumor necrosis factor‑α, interleukin‑8 and sleep monitoring in patients with obstructive sleep apnea syndrome

Hao Ming, Aimin Tian, Bing Liu, Yuqiang Hu, Chen Liu, Renjie Chen, Liangjun Cheng
Pages: 1766-1770
Published online on: 18 December 2018

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Article Open Access

Effect of PI3K/Akt/mTOR signaling pathway on JNK3 in Parkinsonian rats

Ying Chen, Xiaozhen Zheng, Ying Wang, Junjie Song
Pages: 1771-1775
Published online on: 20 December 2018

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Article Open Access

Efficacy of dexmedetomidine in reducing post‑operative pain and improving the quality of recovery in patients with burn wounds undergoing tangential excision skin grafting

Meiru Jiang, Qiaoxia Sun, Ganggang Liu, Hua Qu, Jiahai Ma
Pages: 1776-1782
Published online on: 07 January 2019

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Article Open Access

Effects of paraquat on IL‑6 and TNF‑α in macrophages

Jie Huang, Ning Ning, Weiwei Zhang
Pages: 1783-1789
Published online on: 14 December 2018

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Article Open Access

Correlation of the expression of inflammatory factors with expression of apoptosis-related genes Bax and Bcl-2, in burned rats

Zhixue Wang, Jifeng Fang, Jizhou Xiao
Pages: 1790-1796
Published online on: 20 December 2018

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Article Open Access

Long non‑coding RNA HIF1A‑AS1 is upregulated in intracranial aneurysms and participates in the regulation of proliferation of vascular smooth muscle cells by upregulating TGF‑β1

Jiaming Xu, Yang Zhang, Lisheng Chu, Weiyan Chen, Yueguang Du, Jingjing Gu
Pages: 1797-1801
Published online on: 28 December 2018

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Article Open Access

A cost minimization analysis comparing minimally‑invasive with open reduction surgical techniques for pelvic ring fracture

Liang Ma, Lei Ma, Yu Chen, Yifeng Jiang, Qiang Su, Qian Wang, Yanhong Zhu
Pages: 1802-1812
Published online on: 04 January 2019

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Article

Bouveret's syndrome: A rare presentation of gastric outlet obstruction

Ya‑Bin Yu, Yan Song, Jian‑Bo Xu, Fu‑Zhen Qi
Pages: 1813-1816
Published online on: 03 January 2019

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Article

microRNA‑1273g‑3p is a useful non‑invasive test for the prediction of liver fibrosis in patients with chronic hepatitis C

Yuemin Nan, Xuemin Niu, Rongqi Wang, Suxian Zhao, Na Fu, Jinghua Du, Yang Wang, Baoyu Wang, Yuguo Zhang
Pages: 1817-1824
Published online on: 19 December 2018

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Article

Clinical significance of autoantibodies in the assessment and treatment of idiopathic membranous nephropathy

Wen‑Wen Han, Li‑Jun Tang, Xiang‑Lei Kong, Huan Yang, Dong‑Mei Xu
Pages: 1825-1830
Published online on: 18 December 2018

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Article

Biodegradable ciprofloxacin‑incorporated waterborne polyurethane polymers prevent bacterial biofilm formation in vitro

Yuchen Xu, Jianzhong Wang, Zongyao Hao, Sai Wang, Chaozhao Liang
Pages: 1831-1836
Published online on: 19 December 2018

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Case Report

Kimura's disease associated with IgA nephropathy: A case report

Wei Zhang, Ancharaz Preeatum, Chunyan Liu
Pages: 1837-1840
Published online on: 17 December 2018

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Article

MicroRNA‑761 is downregulated in colorectal cancer and regulates tumor progression by targeting Rab3D

Yupeng Ren, Gang Shi, Peng Jiang, Qingkai Meng
Pages: 1841-1846
Published online on: 21 December 2018

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Article

Hemichannel‑mediated volume regulation contributes to IPC‑induced cardiomyocyte protection

Wenying Wang, Dedong Zheng, Huiya Li, Jinhua Huang, Huijun Chen, Teng Ying, Jun Fang, Yukun Luo
Pages: 1847-1854
Published online on: 21 December 2018

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Article

The mitochondrial tRNAAla 5587T>C and tRNALeu(CUN) 12280A>G mutations may be associated with hypertension in a Chinese family

Lin Lin, Peng Cui, Zhipeng Qiu, Min Wang, Yingchao Yu, Jing Wang, Qian Sun, Hairong Zhao
Pages: 1855-1862
Published online on: 28 December 2018

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Article

Incremental effect of liraglutide on traditional insulin injections in rats with type 2 diabetes mellitus by maintaining glycolipid metabolism and cardiovascular function

Qian Huang, Chan Liu, Jia‑Rui Li, Ling Zhang, Fu‑Chang Huang, Dan Wang, Ya‑Jing Luo
Pages: 1863-1869
Published online on: 03 January 2019

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Article

Discrimination of Burkholderia gladioli pv.alliicola and B. cepacia complex using the gyrB gene of B. gladioli pv. alliicola

Lun Zhang, Wenna Gao, Youping Yin, Zhongkang Wang
Pages: 1870-1876
Published online on: 28 December 2018

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Article

Application of auditory cortical evoked potentials for auditory assessment in people using auditory prosthesis

Jian‑Hua Deng, Ji‑Hong Du, Xin‑Rui Ma, Pei‑Fang Zhang
Pages: 1877-1883
Published online on: 28 December 2018

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Article

Inhibition of HIF‑1α restrains fracture healing via regulation of autophagy in a rat model

Junjie Qiao, Jiang Huang, Meng Zhou, Guanglei Cao, Huiliang Shen
Pages: 1884-1890
Published online on: 19 December 2018

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Article

Diagnostic utility of central damage determination in glaucoma by magnetic resonance imaging: An observational study

Mu Li, Manlin Ke, Yinwei Song, Ketao Mu, Hong Zhang, Zhiqi Chen
Pages: 1891-1895
Published online on: 24 December 2018

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Article

HOXA1 upregulation is associated with poor prognosis and tumor progression in breast cancer

Jintao Liu, Jinquan Liu, Xinyi Lu
Pages: 1896-1902
Published online on: 28 December 2018

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Article

Regulatory effect of miR‑421 on humeral fracture and heterotopic ossification in elderly patients

Chunfang Ju, Zhiyun Lv, Cheng Zhang, Yujuan Jiao
Pages: 1903-1911
Published online on: 02 January 2019

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Article

miR‑34a alleviates spinal cord injury via TLR4 signaling by inhibiting HMGB‑1

Jianmin Zhou, Ou Shuang, Jian Li, Zijun Cai, Chong Wu, Wenyu Wang
Pages: 1912-1918
Published online on: 17 December 2018

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Article

Plasma microRNA: A novel non‑invasive biomarker for HBV‑associated liver fibrosis staging

Tie‑Zheng Wang, Dong‑Dong Lin, Bo‑Xun Jin, Xiang‑Ying Sun, Ning Li
Pages: 1919-1929
Published online on: 19 December 2018

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Article

MicroRNA‑186 promotes cell proliferation and inhibits cell apoptosis in cutaneous squamous cell carcinoma by targeting RETREG1

Xinde Hu, Yifeng Liu, Ping Ai, Shuguang He, Lingzhi Liu, Chaoying Chen, Yuansheng Tan, Ting Wang
Pages: 1930-1938
Published online on: 07 January 2019

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Article

One‑year clinical outcome of angiography, fractional flow reserve and instantaneous wave‑free ratio guided percutaneous coronary intervention: A PRISMA‑compliant meta‑analysis

Stefan Baumann, Klara S. E. Mueller, Svetlana Hetjens, Frederik Eder, Antonia C. Schaefer, Tobias Becher, Martin Borggrefe, Ibrahim Akin, Dirk Loßnitzer
Pages: 1939-1951
Published online on: 07 January 2019

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Article

Comparison of pressure‑regulated volume control ventilation and pressure control ventilation in patients with abdominal compartment syndrome

Jiangtao Yin, Xin Pan, Jue Jia, Shuangshuang Sun, Bing Wan
Pages: 1952-1958
Published online on: 07 January 2019

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Review Open Access

Topical treatments for diabetic neuropathic pain (Review)

Xi‑Ding Yang, Ping‑Fei Fang, Da‑Xiong Xiang, Yong‑Yu Yang
Pages: 1963-1976
Published online on: 15 January 2019

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Review

Epidemiology, diagnosis and treatment of moyamoya disease (Review)

Hui Zhang, Lijian Zheng, Lei Feng
Pages: 1977-1984
Published online on: 25 January 2019

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Review Open Access

The diagnostic value of circulating microRNAs in heart failure (Review)

Yao‑Meng Huang, Wei‑Wei Li, Jun Wu, Mei Han, Bing‑Hui Li
Pages: 1985-2003
Published online on: 15 January 2019

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Article Open Access

Comparison of different cell culture plates for the enrichment of non‑adherent human mononuclear cells

Annett Klinder, Jana Markhoff, Anika Jonitz‑Heincke, Philipp Sterna, Achim Salamon, Rainer Bader
Pages: 2004-2012
Published online on: 25 January 2019

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Article Open Access

Evaluation of complications of totally implantable central venous port system insertion

Dong Hyun Kim, Dong Yeon Ryu, Hyuk Jae Jung, Sang Su Lee
Pages: 2013-2018
Published online on: 18 January 2019

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Article Open Access

Association between RAGE variants and the susceptibility to atherosclerotic lesions in Chinese Han population

Xiaolin Zhang, Minghui Cheng, Fangnian Tong, Xue Su
Pages: 2019-2030
Published online on: 09 January 2019

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Article Open Access

Anti‑bacterial activity of mutant chensinin‑1 peptide against multidrug‑resistant Pseudomonas aeruginosa and its effects on biofilm‑associated gene expression

Zhiyuan Yu, Yi Kong, Zhenqin Luo, Tongtong Liu, Jinguan Lin
Pages: 2031-2038
Published online on: 17 January 2019

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Article Open Access

Candidate genes associated with the effect of rosiglitazone on glycemic control and cardiovascular system in the treatment of type 2 diabetes mellitus

Xiaoli Wu
Pages: 2039-2046
Published online on: 09 January 2019

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Value analysis of CD69 combined with EGR1 in the diagnosis of coronary heart disease

Jianqiao Peng, Yi Xiang
Pages: 2047-2052
Published online on: 15 January 2019

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B‑cell activating factor receptor expression is associated with germinal center B‑cell maintenance

Francisco Josué Carrillo‑Ballesteros, Edith Oregon‑Romero, Ramon Antonio Franco‑Topete, Luis Humberto Govea‑Camacho, Alvaro Cruz, José Francisco Muñoz‑Valle, Felipe Jesús Bustos‑Rodríguez, Ana Laura Pereira‑Suárez, Claudia Azucena Palafox‑Sánchez
Pages: 2053-2060
Published online on: 15 January 2019

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E‑cadherin regulates biological behaviors of neural stem cells and promotes motor function recovery following spinal cord injury

Dong Chen, Siyuan Hu, Jie Liu, Shaohua Li
Pages: 2061-2070
Published online on: 15 January 2019

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Effect of baicalin on renal function in patients with diabetic nephropathy and its therapeutic mechanism

Mingzheng Yang, Lin Kan, Lianye Wu, Yingchun Zhu, Qing Wang
Pages: 2071-2076
Published online on: 17 January 2019

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Article

Downregulation of microRNA‑374a predicts poor prognosis in human glioma

Qiang Dong, Guoqiang Yuan, Min Liu, Qiqi Xie, Jianhong Hu, Maolin Wang, Shangyu Liu, Xiaojun Ma, Yawen Pan
Pages: 2077-2084
Published online on: 21 January 2019

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Predicting the target genes of miRNAs in preterm via targetscore algorithm

Kexin Lu, Junzhi Huang, Yandong Yang, Dongli Lu
Pages: 2085-2090
Published online on: 16 January 2019

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Berberine attenuates hepatic oxidative stress in rats with non‑alcoholic fatty liver disease via the Nrf2/ARE signalling pathway

Yuanjun Deng, Kairui Tang, Runsen Chen, Huan Nie, Shu Liang, Jinwen Zhang, Yupei Zhang, Qinhe Yang
Pages: 2091-2098
Published online on: 28 January 2019

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Protective effect of remote ischemic pre‑conditioning on patients undergoing cardiac bypass valve replacement surgery: A randomized controlled trial

Xiuling Jin, Liangrong Wang, Liling Li, Xiyue Zhao
Pages: 2099-2106
Published online on: 21 January 2019

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Prediction of pivotal pathways and hub genes associated with osteoporosis by Gibbs sampling

Yiyun Tan, Lei Liu
Pages: 2107-2112
Published online on: 16 January 2019

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Identification of key transcription factors - gene regulatory network related with osteogenic differentiation of human mesenchymal stem cells based on transcription factor prognosis system

Xuefeng Kang, Yong Sun, Zhao Zhang
Pages: 2113-2122
Published online on: 14 January 2019

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VEGF and sFLT-1 in serum of PIH patients and effects on the foetus

Yanhong Tang, Wenfeng Ye, Xia Liu, Yan Lv, Changfang Yao, Jiang Wei
Pages: 2123-2128
Published online on: 18 January 2019

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Screening of miRNA target genes in coronary artery disease by variational Bayesian Gaussian mixture model

Xiao‑Lin Ma, Xu Yang, Rui Fan
Pages: 2129-2136
Published online on: 22 January 2019

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Article Open Access

Therapeutic effects of rituximab combined with cyclophosphamide on refractory idiopathic thrombocytopenic purpura

Jiuhe Wang, Bin Wang, Zhonghui Sun, Kezeng Xue
Pages: 2137-2142
Published online on: 23 January 2019

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Apurinic/apyrimidinic endonuclease/redox factor 1 (APE1) alleviates myocardial hypoxia‑reoxygenation injury by inhibiting oxidative stress and ameliorating mitochondrial dysfunction

Jie Hao, Hong Du, Fan Liu, Jing‑Chao Lu, Xiu‑Chun Yang, Wei Cui
Pages: 2143-2151
Published online on: 29 January 2019

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Article Open Access

MicroRNA‑144 attenuates cardiac ischemia/reperfusion injury by targeting FOXO1 Corrigendum in /10.3892/etm.2020.8424

Lusha E, Hong Jiang, Zhibing Lu
Pages: 2152-2160
Published online on: 09 January 2019

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Article

Luteolin improves heart preservation through inhibiting hypoxia‑dependent L‑type calcium channels in cardiomyocytes

Qingfeng Yan, Yueping Li, Jia Yan, Ying Zhao, Yunzhong Liu, Su Liu
Pages: 2161-2171
Published online on: 29 January 2019

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Article Open Access

Application of protein chip combined with SELDI‑TOF‑MS detection to investigate serum protein expression in patients with silicosis fibrosis

Guitao Liu, Junfeng Yu, Cuidong Li, Xiaoyun Zhou, Liping Nie, Yanhua Wei, Wenyu Wang, Ying Zhang, Nuziguli Nusilaiti, Ping Hua, Xiaohua Wang, Wenlong Wei, Xinyan Li
Pages: 2172-2184
Published online on: 11 January 2019

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Article Open Access

Anti‑obesity effect in high‑fat‑diet‑induced obese C57BL/6 mice: Study of a novel extract from mulberry (Morus alba) leaves fermented with Cordyceps militaris

Mi Rim Lee, Ji Eun Kim, Jun Young Choi, Jin Ju Park, Hye Ryeong Kim, Bo Ram Song, Young Whan Choi, Kyung Mi Kim, Hyunkeun Song, Dae Youn Hwang
Pages: 2185-2193
Published online on: 21 January 2019

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Article Open Access

Treatment of Mullerian duct cyst by combination of transurethral resection and seminal vesiculoscopy: An initial experience

Chenkui Miao, Shouyong Liu, Kai Zhao, Jundong Zhu, Ye Tian, Yuhao Wang, Bianjiang Liu, Zengjun Wang
Pages: 2194-2198
Published online on: 25 January 2019

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The treatment of systematically transplanted gingival mesenchymal stem cells in periodontitis in mice

Wendong Sun, Zhiguo Wang, Quanchen Xu, Huibin Sun, Xiaoxuan Liu, Jianjun Yang, Rundan Hong
Pages: 2199-2205
Published online on: 11 January 2019

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Article Open Access

Composition and diversity analysis of the B‑cell receptor immunoglobulin heavy chain complementarity‑determining region 3 repertoire in patients with acute rejection after kidney transplantation using high‑throughput sequencing

Liusheng Lai, Xianqing Zhou, Huaizhou Chen, Yadan Luo, Weiguo Sui, Jiaxing Zhang, Donge Tang, Qiang Yan, Yong Dai
Pages: 2206-2220
Published online on: 17 January 2019

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Article Open Access

Role of microRNA‑150‑5p/SRCIN1 axis in the progression of breast cancer

Qingfu Lu, Zhaoji Guo, Haixin Qian
Pages: 2221-2229
Published online on: 28 January 2019

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Article Open Access

The effects of simvastatin preconditioning on the expression of caspase-3 after myocardial ischemia reperfusion injury in rats

Weixin Sun, Renyou Pan, Jun Song, Honglin Sun
Pages: 2230-2234
Published online on: 09 January 2019

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Article Open Access

MicroRNA‑708‑5p affects proliferation and invasion of osteosarcoma cells by targeting URGCP

Cong Sui, Debao Liu, Yong Hu, Linlin Zhang
Pages: 2235-2241
Published online on: 15 January 2019

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Article Open Access

Resveratrol suppresses proliferation and induces apoptosis of uterine sarcoma cells by inhibiting the Wnt signaling pathway

Ayuka Mineda, Masato Nishimura, Tomohiro Kagawa, Eri Takiguchi, Takako Kawakita, Akiko Abe, Minoru Irahara
Pages: 2242-2246
Published online on: 28 January 2019

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Article Open Access

Efficacy of bone marrow mesenchymal stem cell transplantation in animal models of pulmonary fibrosis after exposure to bleomycin: A meta‑analysis

Enguo Zhang, Ye Yang, Juan Zhang, Guoyong Ding, Shangya Chen, Cheng Peng, Martin F. Lavin, Abrey J. Yeo, Zhongjun Du, Hua Shao
Pages: 2247-2255
Published online on: 28 January 2019

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Article Open Access

Chrysin protects against renal ischemia reperfusion induced tubular cell apoptosis and inflammation in mice

Mingwei Xu, Hongbo Shi, Dongcao Liu
Pages: 2256-2262
Published online on: 21 January 2019

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Article Open Access

Intraoperative and postoperative effects of TEG-guided platelet transfusion on antiplateletdrug-related intracerebral hemorrhage patients

Hao Zhou, Li Chen, Hongtian He
Pages: 2263-2267
Published online on: 14 January 2019

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Article Open Access

Differential composition of gut microbiota among healthy volunteers, morbidly obese patients and post‑bariatric surgery patients

Fu‑Gang Wang, Ri‑Xing Bai, Wen‑Mao Yan, Ming Yan, Ling‑Yue Dong, Mao‑Min Song
Pages: 2268-2278
Published online on: 25 January 2019

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Article Open Access

Analysis of expression levels of IL-17 and IL-34 and influencing factors for prognosis in patients with lupus nephritis

Yanna Cheng, Xiaojuan Yang, Xijun Zhang, Zhi An
Pages: 2279-2283
Published online on: 14 January 2019

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Article Open Access

MicroRNA‑205‑5p regulates extracellular matrix production in hyperplastic scars by targeting Smad2

Jun Qi, Yifei Liu, Kesu Hu, Yi Zhang, Yangyang Wu, Xia Zhang
Pages: 2284-2290
Published online on: 21 January 2019

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Article Open Access

Effect of HIFU on endometrial receptivity and sex hormone level in uterine fibroid patients and analysis of influencing factors for its treatment rate

Yongmei Cui, Yanyan Dong, Bingcheng Guo, Cuihong Xing, Xiaohui Gao, Dexing Su
Pages: 2291-2297
Published online on: 22 January 2019

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Article Open Access

Crosstalk analysis of dysregulated pathways in preeclampsia

Tao Wang, Xing-Zhen Shi, Wen-Hua Wu
Pages: 2298-2304
Published online on: 16 January 2019

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Article Open Access

Treatment of patients with systemic‑onset juvenile idiopathic arthritis with tacrolimus

Dongdong Wang, Xiao Chen, Zhiping Li
Pages: 2305-2309
Published online on: 15 January 2019

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Article Open Access

Microvesicles containing miR-34a induce apoptosis of proximal tubular epithelial cells and participate in renal interstitial fibrosis

Hongyan Li, Yuexia Xu, Qin Zhang, Hongfang Xu, Yan Xu, Kai Ling
Pages: 2310-2316
Published online on: 24 January 2019

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Article Open Access

Acetazolamide attenuates cardiac fibrosis induced by aortic constriction through inhibiting transforming growth factor-β1/Smad2 signaling pathway in mice

Qianqian Huo, Ting Wang, Tao Wang, Rui Zhang
Pages: 2317-2321
Published online on: 28 January 2019

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Article Open Access

A clinically relevant blunt spinal cord injury model in the regeneration competent axolotl (Ambystoma mexicanum) tail

Mathias Møller Thygesen, Henrik Lauridsen, Michael Pedersen, Dariusz Orlowski, Trine Werenberg Mikkelsen, Mikkel Mylius Rasmussen
Pages: 2322-2328
Published online on: 21 January 2019

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Article

α‑lipoic acid attenuates spatial learning and memory impairment induced by hepatectomy

Yuan Zhang, Yun‑Luo Lv, Yan‑Na Si, Jianwei Zhou, Yanning Qian, Hong‑Guang Bao
Pages: 2329-2333
Published online on: 25 January 2019

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Article

Inhibition of NET‑1 suppresses proliferation and promotes apoptosis of hepatocellular carcinoma cells by activating the PI3K/AKT signaling pathway

Xiangjun Sun, Mingchun Wang, Fenghua Zhang, Xiao Kong
Pages: 2334-2340
Published online on: 29 January 2019

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Article

Aggravated mucosal and immune damage in a mouse model of ulcerative colitis with stress

Yanxia Gong, Wei Niu, Yanping Tang, Qingyu Zhang, Simiao Liu, Xi Liu, Xiao Wang, Yang Xu
Pages: 2341-2348
Published online on: 09 January 2019

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Article

Mitochondrial separation protein inhibitor inhibits cell apoptosis in rat lungs during intermittent hypoxia

Dan Zhao, Chen‑Yi Yin, Xian‑Wei Ye, Zi‑Fen Wan, De‑Gang Zhao, Xiang‑Yan Zhang
Pages: 2349-2358
Published online on: 25 January 2019

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Article

miR‑212 regulated by HIF‑1α promotes the progression of pancreatic cancer

Hui Yue, Lin Liu, Zhenguo Song
Pages: 2359-2365
Published online on: 29 January 2019

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Article

Role and mechanism of nursing cooperation and tetramethylpyrazine application in post‑operative pain in patients undergoing total knee arthroplasty

Chang Liu, Rui Liu, Meiling Tang, Xinxin Yang, Xiuping Gong
Pages: 2366-2372
Published online on: 25 January 2019

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Article

Oestrogen inhibits PTPRO to prevent the apoptosis of renal podocytes

Wei Ren, Huiru Yi, Ying Bao, Yingru Liu, Xinru Gao
Pages: 2373-2380
Published online on: 14 January 2019

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Article

Cilostazol protects rats against alcohol‑induced hepatic fibrosis via suppression of TGF‑β1/CTGF activation and the cAMP/Epac1 pathway

Kun Han, Yanting Zhang, Zhenwei Yang
Pages: 2381-2388
Published online on: 28 January 2019

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Article

Evaluation of efficacy and nephrotoxicity during vancomycin therapy: A retrospective study in China

Liping Wang, Qing Yuan, Min Tan, Shuanshuan Xie, Jufang Wu, Xiaolian Song, Changhui Wang
Pages: 2389-2396
Published online on: 21 January 2019

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Article

Epidermal growth factor treatment has protective effects on the integrity of the blood‑brain barrier against cerebral ischemia injury in bEnd3 cells

Shu Yang, Hong Jin, Zhi‑Gang Zhao
Pages: 2397-2402
Published online on: 21 January 2019

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March-2026 Volume 31 Issue 3

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Article Open Access

Effect of SGLT2 inhibitors on heart failure outcomes in patients with and without diabetes: A systematic review and meta‑analysis of randomized controlled trials

Duaa Abdullah Bafail, Noura Hamdi Alhalees
Article Number: 84
Published online on: 28 January 2026

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Article Open Access

Exploring the protective mechanisms and therapeutic potential of carnosic acid against acute respiratory distress syndrome through molecular docking, molecular dynamics and experimental verification

Quan Li, Lili Ding, Haijun Sun, Weichao Ding, Mengmeng Wang, Zhaorui Sun, Congxue Ma
Article Number: 83
Published online on: 28 January 2026

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Review

Exploring the roots of schizophrenia: Current research and future directions (Review)

Shuang Lv, Chunxia Luo
Article Number: 82
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] miR‑146a‑5p protects against renal injury in MRL/lpr mice via improvement of the Treg/Th17 imbalance by targeting the TRAF6/NF‑κB axis

Jiajia Teng, Feng Yang, Xiaoling Li
Article Number: 81
Published online on: 28 January 2026

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[Retracted] MicroRNA‑24‑3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl‑2‑like protein 11

Huanxin Zhang, Shizhen Xue, Yi Feng, Jun Shen, Jixian Zhao
Article Number: 80
Published online on: 26 January 2026

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Efficacy and safety of unilateral biportal endoscopy vs. percutaneous endoscopic interlaminar approach in lumbar disc herniation: A meta‑analysis​

Yuhao Gao, Fangzheng He, Ji Wen, Shilei Qin, Pengfei Han, Yunfeng Xu
Article Number: 79
Published online on: 23 January 2026

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Case Report Open Access

Intralobar pulmonary sequestration coexisting with pulmonary cryptococcosis: A case report and literature review

Dan Cheng, Yue Wang, Jun Li, Dan Yu, Yunyun Wang, Jinbo Fan, Jiankun Wang, Liqun He
Article Number: 78
Published online on: 23 January 2026

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Tumor‑associated macrophages suppress estrogen receptor‑β expression in triple‑negative breast cancer through the PI3K/AKT pathway

Qiulei Zhang, Di Guo, Gaoran Xu, Rong Xie, Yuqing Deng, Peng Fu, Jinnan Wan
Article Number: 77
Published online on: 21 January 2026

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Development of a diagnostic model for esophageal achalasia assessed by esophageal high‑resolution manometry using artificial intelligence

Maiko Tabuchi, Yasuhiko Nakao, Hitomi Minami, Hiroko Inomata, Junya Shiota, Taro Akashi, Keiichi Hashiguchi, Moto Kitayama, Kayoko Matsushima, Naoyuki Yamaguchi, Yuko Akazawa, Hisamitsu Miyaaki
Article Number: 76
Published online on: 21 January 2026

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Case Report

Use of metagenomic next‑generation sequencing to diagnose Tropheryma whipplei infection‑related pneumonia: A case report

Yutu Luo, Haibing Ding, Jiahua Pan, Guangyang Xu
Article Number: 75
Published online on: 21 January 2026

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Effect of rivaroxaban on DNA damage in an ischemia-reperfusion model: Evaluation of 8‑OHdG levels

Ceren Sayarer, Abidin Cenk Erdal, Tuğra Gençpinar, Özlem Gürsoy Doruk, Tuncay Küme
Article Number: 74
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Hepatoprotective activity of chrysin is mediated through TNF‑α in chemically‑induced acute liver damage: An in vivo study and molecular modeling 

Anca Hermenean, Teodora Mariasiu, Inmaculada Navarro‑González, Josefina Vegara‑Meseguer, Eftimie Miuțescu, Sandipan Chakraborty, Horacio Pérez-Sánchez
Article Number: 73
Published online on: 21 January 2026

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Retraction Open Access

[Retracted] Gambogic acid suppresses colon cancer cell activity in vitro

Zailong Zhou, Jian Ma
Article Number: 72
Published online on: 19 January 2026

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Case Report

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review

Burak Menekse, Enes Ucgul, Abdullatif Bakir, Sema Hepsen, Ilknur Ozturk Unsal, Muhammed Kizilgul, Takako Araki, Erman Cakal
Article Number: 71
Published online on: 16 January 2026

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Postoperative hypofractionated proton beam therapy to control recurrent paraganglioma at the jugular foramen: A case report

Wei Wang, Yingxia Yuan, Jiwei Bai, Yue Zou, Dongxue Zhou, Jun Zhao, Shuyan Zhang, Zishen Wang, Jie Wang, Jingjing Kong, Lu Yang, Masashi Mizumoto, Hideyuki Sakurai, Shosei Shimizu
Article Number: 70
Published online on: 16 January 2026

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Article

Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury

Ruoran Wang, Min He, Jianguo Xu
Article Number: 69
Published online on: 16 January 2026

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Retraction Open Access

[Retracted] β‑asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal‑regulated kinase signaling pathway

Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong Li
Article Number: 68
Published online on: 12 January 2026

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Case Report Open Access

Rare co‑occurrence of gastrointestinal stromal tumors and leiomyomas: A case report and review of the literature

Yu Zhang, Xiaoqiong Shi, Wenfu Xie, Meilin He, Shan Zhang, Xue Peng, Hao Lei, Xulei Li, Haiying Liu, Qiao Shu, Fangyuan Zou, Mingyong Wei
Article Number: 67
Published online on: 09 January 2026

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Article Open Access

No increased risk of hepatic enzyme abnormalities with non‑peptidic thrombopoietin receptor agonists in immune thrombocytopenia: A meta‑analysis of randomized controlled trials

Nan Shen, Rang Wu, Tiantian Lu, Song Liu, Yazhou Jiang, Jingjing Yan, Tao Ning, Chang Dong, Jianqin Li, Suyue Zhu
Article Number: 66
Published online on: 09 January 2026

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Case Report

Submucosal colonic fecalith mimicking a submucosal malignant tumor at the anastomotic site after colon cancer: A case report

Motoaki Yuhi, Masatsugu Hiraki, Shin Takesue, Mariko Hashiguchi, Megumi Nishiyama, Yoshiaki Egashira, Tatsuya Manabe, Hirokazu Noshiro
Article Number: 65
Published online on: 08 January 2026

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Article

Clinical characteristics of acute primary angle closure following COVID‑19 during the Omicron outbreak in China

Jianhui Zhang, Yingying Xue, Liu Zhang, Yuhong Wang, Shancheng Si
Article Number: 64
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Aberrant expression and mechanism of miR‑130b‑3p/phosphatase and tensin homolog in nephroblastoma in children

Yifeng Hu, Jingtie Yan
Article Number: 63
Published online on: 05 January 2026

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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April-2026 Volume 31 Issue 4

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