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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March-2019 Volume 17 Issue 3

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Article Open Access

Clinical effects of lentinan combined with budesonide inhalation in treating acute exacerbation of chronic obstructive pulmonary disease under mechanical ventilation

Jian Sun, Gang Zhao
Pages: 1503-1508
Published online on: 03 January 2019

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Article Open Access

MicroRNA‑375 inhibits esophageal squamous cell carcinoma proliferation through direct targeting of SP1 Retraction in /10.3892/etm.2025.12990

Hui Xu, Jialong Jiang, Jingjun Zhang, Liang Cheng, Song Pan, Yuanhai Li
Pages: 1509-1516
Published online on: 17 December 2018

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Article Open Access

Effect of oxaliplatin combined with 5-fluorouracil on treatment efficacy of radiotherapy in the treatment of elderly patients with rectal cancer

Jinfen Xu, Xia Li, Xinming Lv
Pages: 1517-1522
Published online on: 20 December 2018

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Article Open Access

Allicin suppresses the migration and invasion in cervical cancer cells mainly by inhibiting NRF2 Retraction in /10.3892/etm.2024.12659

Qiumei Zhang, Dongmei Yang
Pages: 1523-1528
Published online on: 17 December 2018

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Article Open Access

Elevated expression of microRNA‑378 in children with asthma aggravates airway remodeling by promoting the proliferation and apoptosis resistance of airway smooth muscle cells

Peng Li, Xufang Lang, Shungang Xia
Pages: 1529-1536
Published online on: 28 December 2018

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Article Open Access

miR‑181b‑5p promotes proliferation and inhibits apoptosis of hypertrophic scar fibroblasts through regulating the MEK/ERK/p21 pathway

Bo Liu, Zhe Guo, Weiming Gao
Pages: 1537-1544
Published online on: 07 January 2019

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Article Open Access

Effect of total glucosides of paeony on the changes of IL-4 and ICAM-1 levels in eczema mouse model serum

Meihua Zhou, Hongfeng Sui
Pages: 1545-1550
Published online on: 20 December 2018

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Article Open Access

Protective effect of Xin‑Ji‑Er‑Kang on cardiovascular remodeling in high salt‑induced hypertensive mice

Guangyao Huang, Pan Cheng, Ling Ding, Li Wang, Juan Hu, Yongxue Zhang, Guowei Cai, Meiling Chen, Aizong Shen, Shan Gao
Pages: 1551-1562
Published online on: 17 December 2018

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Article Open Access

Clinical efficacy evaluation of treatment of different degrees of retinal vein occlusion with ranibizumab combined with an argon ion laser

Dingding Wang, Xiaoyi Wang, Kunfang Wu, Juanjuan Wang, Guihua Xu, Zilin Chen
Pages: 1563-1568
Published online on: 21 December 2018

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Article Open Access

Resveratrol suppresses the invasion and migration of human gastric cancer cells via inhibition of MALAT1‑mediated epithelial‑to‑mesenchymal transition

Zhuying Yang, Qigui Xie, Zhanlei Chen, Haibin Ni, Liang Xia, Qiufeng Zhao, Zhiyun Chen, Peifeng Chen
Pages: 1569-1578
Published online on: 28 December 2018

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Article Open Access

microRNA‑196a attenuates ischemic brain injury in rats by directly targeting high mobility group A1

Junan Hu, Wei Shen
Pages: 1579-1586
Published online on: 04 January 2019

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Article Open Access

Expression of Notch-1 and nuclear factor-κB signal pathway in myocardial cells of coronary heart disease rats

Jiahui Zheng, Shufeng Zhang, Tingting Wang
Pages: 1587-1592
Published online on: 21 December 2018

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Article Open Access

3D culture enhances chemoresistance of ALL Jurkat cell line by increasing DDR1 expression

Jun Guo, Chunting Zhao, Ruyong Yao, Aihua Sui, Lingjie Sun, Xiaodan Liu, Shaoling Wu, Zhan Su, Tianlan Li, Shanshan Liu, Yan Gao, Jiaxiu Liu, Xianqi Feng, Wei Wang, Hongguo Zhao, Zhongguang Cui, Guanglun Li, Fanjun Meng
Pages: 1593-1600
Published online on: 04 January 2019

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Article Open Access

Experimental study of TNF‑α receptor gene transfection by ultrasound‑targeted microbubble destruction to treat collagen‑induced arthritis in rats in vivo

Liyun Wang, Xiaolan Tang, Xi Xiang, Yuanjiao Tang, Li Qiu
Pages: 1601-1610
Published online on: 07 January 2019

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Article Open Access

Cholinesterase inhibitors and memantine for Parkinson's disease dementia and Lewy body dementia: A meta‑analysis

Yan‑Hong Meng, Pan‑Pan Wang, Ya‑Xue Song, Jian‑Hua Wang
Pages: 1611-1624
Published online on: 24 December 2018

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Article Open Access

Effect of memantine combined with citalopram on cognition of BPSD and moderate Alzheimer's disease: A clinical trial

Tiantian Zhou, Jindong Wang, Cuiyu Xin, Lingli Kong, Chunxia Wang
Pages: 1625-1630
Published online on: 21 December 2018

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Article Open Access

Ropivacaine at different concentrations on intrapartum fever, IL‑6 and TNF‑α in parturient with epidural labor analgesia

Xianjin Zhou, Jiang Li, Shengqiong Deng, Zhendong Xu, Zhiqiang Liu
Pages: 1631-1636
Published online on: 20 December 2018

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Article Open Access

Downregulated MEG3 participates in rheumatoid arthritis via promoting proliferation of fibroblast‑like synoviocytes

Xin Lu, Jun Qian
Pages: 1637-1642
Published online on: 14 December 2018

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Article Open Access

Therapeutic effect of the epidermal growth factor on diabetic foot ulcer and the underlying mechanisms

Juanzi Zhang, Wenxian Hu, Qixian Diao, Zhaowei Wang, Jin Miao, Xiao Chen, Zhijun Xue
Pages: 1643-1648
Published online on: 24 December 2018

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Article Open Access

Adenovirus‑mediated herpes simplex virus thymidine kinase gene therapy combined with ganciclovir induces hepatoma cell apoptosis

Haitao Zhang, Ling Qin, Chaolu Li, Jianyi Jiang, Libo Sun, Xiaofei Zhao, Ning Li
Pages: 1649-1655
Published online on: 02 January 2019

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Article Open Access

Endovascular treatment of middle cerebral artery aneurysm with a (LVIS) device: Comparison of LVIS stent and non‑LVIS stent

Feiyu Chen, Xiaoyu Fang
Pages: 1656-1662
Published online on: 28 December 2018

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Article Open Access

Insulin‑like growth factor 2 promotes the adipogenesis of hemangioma‑derived stem cells

Kui Zhang, Fan Wang, Jun Huang, Yin Lou, Juan Xie, Honghong Li, Dongsheng Cao, Xueying Huang
Pages: 1663-1669
Published online on: 24 December 2018

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Article Open Access

Novel triazole analogs of apigenin‑7‑methyl ether exhibit potent antitumor activity against ovarian carcinoma cells via the induction of mitochondrial‑mediated apoptosis

Yuyan Qi, Zhaoxia Ding, Yushuang Yao, Dehua Ma, Feifei Ren, Hongjuan Yang, Aiping Chen
Pages: 1670-1676
Published online on: 28 December 2018

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Article Open Access

Butyrate stimulates hepatic gluconeogenesis in mouse primary hepatocytes

Xueying Ji, Feiye Zhou, Yuqing Zhang, Ruyuan Deng, Wan Xu, Mengyao Bai, Yun Liu, Li Shao, Xiao Wang, Libin Zhou
Pages: 1677-1687
Published online on: 28 December 2018

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Article Open Access

The activation of BDNF reduced inflammation in a spinal cord injury model by TrkB/p38 MAPK signaling

Jiedong Liang, Gui Deng, He Huang
Pages: 1688-1696
Published online on: 18 December 2018

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Article Open Access

Downregulation of miR‑183 inhibits the growth of PANC‑1 pancreatic cancer cells in vitro and in vivo, and increases chemosensitivity to 5‑fluorouracil and gemcitabine

Xiaoping Yang, Wei Wang, Xiong Zhang, Qi Zou, Lei Cai, Bo Yu
Pages: 1697-1705
Published online on: 19 December 2018

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Article Open Access

MicroRNA‑494‑3p protects rat cardiomyocytes against septic shock via PTEN

Peng Wu, Lingchen Kong, Jianzhong Li
Pages: 1706-1716
Published online on: 19 December 2018

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Article Open Access

Regulation of TGF‑β1 on PI3KC3 and its role in hypertension‑induced vascular injuries

Qin Zhang, Hu Liu, Jun Yang
Pages: 1717-1727
Published online on: 21 December 2018

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Article Open Access

Circular RNA hsa_circ_0014243 may serve as a diagnostic biomarker for essential hypertension

Shuying Zheng, Tianlun Gu, Xingjie Bao, Jihan Sun, Jinshun Zhao, Tao Zhang, Lina Zhang
Pages: 1728-1736
Published online on: 17 December 2018

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Article Open Access

Budd‑Chiari syndrome in Behcet's disease: A report of two cases

Jun Zhou, Yu Wang, Yiming Liu, Hanjiang Zeng, Hanshi Xu, Fan Lian
Pages: 1737-1741
Published online on: 24 December 2018

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Article Open Access

Epigallocatechin gallate inhibits cell growth and regulates miRNA expression in cervical carcinoma cell lines infected with different high‑risk human papillomavirus subtypes

Yu Zhu, Yongfang Huang, Mingmin Liu, Qi Yan, Wanhong Zhao, Ping Yang, Qin Gao, Juanjuan Wei, Wenxia Zhao, Lishan Ma
Pages: 1742-1748
Published online on: 24 December 2018

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Article Open Access

Analysis of detection results of thyroid function-related indexes in pregnant women and establishment of the reference interval

Qi Zhou, Yanli Zhang, Jianhua Zhou, Xiangrong Yang, Yuqiang Huang, Huafeng Li, Chunling Ma
Pages: 1749-1755
Published online on: 27 December 2018

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Article Open Access

Expression of Hcy and blood lipid levels in serum of CHD patients and analysis of risk factors for CHD

Weijing Liu, Tao Wang, Pengfei Sun, Yanju Zhou
Pages: 1756-1760
Published online on: 18 December 2018

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Article Open Access

Effect of testosterone on the expression of PPARγ mRNA in PCOS patients

Jinghe Cao, Gulijianati Maowulieti, Tao Yu
Pages: 1761-1765
Published online on: 14 December 2018

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Article Open Access

Inflammatory cytokines tumor necrosis factor‑α, interleukin‑8 and sleep monitoring in patients with obstructive sleep apnea syndrome

Hao Ming, Aimin Tian, Bing Liu, Yuqiang Hu, Chen Liu, Renjie Chen, Liangjun Cheng
Pages: 1766-1770
Published online on: 18 December 2018

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Article Open Access

Effect of PI3K/Akt/mTOR signaling pathway on JNK3 in Parkinsonian rats

Ying Chen, Xiaozhen Zheng, Ying Wang, Junjie Song
Pages: 1771-1775
Published online on: 20 December 2018

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Article Open Access

Efficacy of dexmedetomidine in reducing post‑operative pain and improving the quality of recovery in patients with burn wounds undergoing tangential excision skin grafting

Meiru Jiang, Qiaoxia Sun, Ganggang Liu, Hua Qu, Jiahai Ma
Pages: 1776-1782
Published online on: 07 January 2019

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Article Open Access

Effects of paraquat on IL‑6 and TNF‑α in macrophages

Jie Huang, Ning Ning, Weiwei Zhang
Pages: 1783-1789
Published online on: 14 December 2018

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Article Open Access

Correlation of the expression of inflammatory factors with expression of apoptosis-related genes Bax and Bcl-2, in burned rats

Zhixue Wang, Jifeng Fang, Jizhou Xiao
Pages: 1790-1796
Published online on: 20 December 2018

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Article Open Access

Long non‑coding RNA HIF1A‑AS1 is upregulated in intracranial aneurysms and participates in the regulation of proliferation of vascular smooth muscle cells by upregulating TGF‑β1

Jiaming Xu, Yang Zhang, Lisheng Chu, Weiyan Chen, Yueguang Du, Jingjing Gu
Pages: 1797-1801
Published online on: 28 December 2018

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Article Open Access

A cost minimization analysis comparing minimally‑invasive with open reduction surgical techniques for pelvic ring fracture

Liang Ma, Lei Ma, Yu Chen, Yifeng Jiang, Qiang Su, Qian Wang, Yanhong Zhu
Pages: 1802-1812
Published online on: 04 January 2019

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Article

Bouveret's syndrome: A rare presentation of gastric outlet obstruction

Ya‑Bin Yu, Yan Song, Jian‑Bo Xu, Fu‑Zhen Qi
Pages: 1813-1816
Published online on: 03 January 2019

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Article

microRNA‑1273g‑3p is a useful non‑invasive test for the prediction of liver fibrosis in patients with chronic hepatitis C

Yuemin Nan, Xuemin Niu, Rongqi Wang, Suxian Zhao, Na Fu, Jinghua Du, Yang Wang, Baoyu Wang, Yuguo Zhang
Pages: 1817-1824
Published online on: 19 December 2018

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Article

Clinical significance of autoantibodies in the assessment and treatment of idiopathic membranous nephropathy

Wen‑Wen Han, Li‑Jun Tang, Xiang‑Lei Kong, Huan Yang, Dong‑Mei Xu
Pages: 1825-1830
Published online on: 18 December 2018

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Article

Biodegradable ciprofloxacin‑incorporated waterborne polyurethane polymers prevent bacterial biofilm formation in vitro

Yuchen Xu, Jianzhong Wang, Zongyao Hao, Sai Wang, Chaozhao Liang
Pages: 1831-1836
Published online on: 19 December 2018

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Case Report

Kimura's disease associated with IgA nephropathy: A case report

Wei Zhang, Ancharaz Preeatum, Chunyan Liu
Pages: 1837-1840
Published online on: 17 December 2018

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Article

MicroRNA‑761 is downregulated in colorectal cancer and regulates tumor progression by targeting Rab3D

Yupeng Ren, Gang Shi, Peng Jiang, Qingkai Meng
Pages: 1841-1846
Published online on: 21 December 2018

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Article

Hemichannel‑mediated volume regulation contributes to IPC‑induced cardiomyocyte protection

Wenying Wang, Dedong Zheng, Huiya Li, Jinhua Huang, Huijun Chen, Teng Ying, Jun Fang, Yukun Luo
Pages: 1847-1854
Published online on: 21 December 2018

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Article

The mitochondrial tRNAAla 5587T>C and tRNALeu(CUN) 12280A>G mutations may be associated with hypertension in a Chinese family

Lin Lin, Peng Cui, Zhipeng Qiu, Min Wang, Yingchao Yu, Jing Wang, Qian Sun, Hairong Zhao
Pages: 1855-1862
Published online on: 28 December 2018

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Article

Incremental effect of liraglutide on traditional insulin injections in rats with type 2 diabetes mellitus by maintaining glycolipid metabolism and cardiovascular function

Qian Huang, Chan Liu, Jia‑Rui Li, Ling Zhang, Fu‑Chang Huang, Dan Wang, Ya‑Jing Luo
Pages: 1863-1869
Published online on: 03 January 2019

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Article

Discrimination of Burkholderia gladioli pv.alliicola and B. cepacia complex using the gyrB gene of B. gladioli pv. alliicola

Lun Zhang, Wenna Gao, Youping Yin, Zhongkang Wang
Pages: 1870-1876
Published online on: 28 December 2018

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Article

Application of auditory cortical evoked potentials for auditory assessment in people using auditory prosthesis

Jian‑Hua Deng, Ji‑Hong Du, Xin‑Rui Ma, Pei‑Fang Zhang
Pages: 1877-1883
Published online on: 28 December 2018

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Article

Inhibition of HIF‑1α restrains fracture healing via regulation of autophagy in a rat model

Junjie Qiao, Jiang Huang, Meng Zhou, Guanglei Cao, Huiliang Shen
Pages: 1884-1890
Published online on: 19 December 2018

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Article

Diagnostic utility of central damage determination in glaucoma by magnetic resonance imaging: An observational study

Mu Li, Manlin Ke, Yinwei Song, Ketao Mu, Hong Zhang, Zhiqi Chen
Pages: 1891-1895
Published online on: 24 December 2018

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Article

HOXA1 upregulation is associated with poor prognosis and tumor progression in breast cancer

Jintao Liu, Jinquan Liu, Xinyi Lu
Pages: 1896-1902
Published online on: 28 December 2018

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Article

Regulatory effect of miR‑421 on humeral fracture and heterotopic ossification in elderly patients

Chunfang Ju, Zhiyun Lv, Cheng Zhang, Yujuan Jiao
Pages: 1903-1911
Published online on: 02 January 2019

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Article

miR‑34a alleviates spinal cord injury via TLR4 signaling by inhibiting HMGB‑1

Jianmin Zhou, Ou Shuang, Jian Li, Zijun Cai, Chong Wu, Wenyu Wang
Pages: 1912-1918
Published online on: 17 December 2018

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Article

Plasma microRNA: A novel non‑invasive biomarker for HBV‑associated liver fibrosis staging

Tie‑Zheng Wang, Dong‑Dong Lin, Bo‑Xun Jin, Xiang‑Ying Sun, Ning Li
Pages: 1919-1929
Published online on: 19 December 2018

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Article

MicroRNA‑186 promotes cell proliferation and inhibits cell apoptosis in cutaneous squamous cell carcinoma by targeting RETREG1

Xinde Hu, Yifeng Liu, Ping Ai, Shuguang He, Lingzhi Liu, Chaoying Chen, Yuansheng Tan, Ting Wang
Pages: 1930-1938
Published online on: 07 January 2019

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Article

One‑year clinical outcome of angiography, fractional flow reserve and instantaneous wave‑free ratio guided percutaneous coronary intervention: A PRISMA‑compliant meta‑analysis

Stefan Baumann, Klara S. E. Mueller, Svetlana Hetjens, Frederik Eder, Antonia C. Schaefer, Tobias Becher, Martin Borggrefe, Ibrahim Akin, Dirk Loßnitzer
Pages: 1939-1951
Published online on: 07 January 2019

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Article

Comparison of pressure‑regulated volume control ventilation and pressure control ventilation in patients with abdominal compartment syndrome

Jiangtao Yin, Xin Pan, Jue Jia, Shuangshuang Sun, Bing Wan
Pages: 1952-1958
Published online on: 07 January 2019

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Review Open Access

Topical treatments for diabetic neuropathic pain (Review)

Xi‑Ding Yang, Ping‑Fei Fang, Da‑Xiong Xiang, Yong‑Yu Yang
Pages: 1963-1976
Published online on: 15 January 2019

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Review

Epidemiology, diagnosis and treatment of moyamoya disease (Review)

Hui Zhang, Lijian Zheng, Lei Feng
Pages: 1977-1984
Published online on: 25 January 2019

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Review Open Access

The diagnostic value of circulating microRNAs in heart failure (Review)

Yao‑Meng Huang, Wei‑Wei Li, Jun Wu, Mei Han, Bing‑Hui Li
Pages: 1985-2003
Published online on: 15 January 2019

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Article Open Access

Comparison of different cell culture plates for the enrichment of non‑adherent human mononuclear cells

Annett Klinder, Jana Markhoff, Anika Jonitz‑Heincke, Philipp Sterna, Achim Salamon, Rainer Bader
Pages: 2004-2012
Published online on: 25 January 2019

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Article Open Access

Evaluation of complications of totally implantable central venous port system insertion

Dong Hyun Kim, Dong Yeon Ryu, Hyuk Jae Jung, Sang Su Lee
Pages: 2013-2018
Published online on: 18 January 2019

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Article Open Access

Association between RAGE variants and the susceptibility to atherosclerotic lesions in Chinese Han population

Xiaolin Zhang, Minghui Cheng, Fangnian Tong, Xue Su
Pages: 2019-2030
Published online on: 09 January 2019

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Article Open Access

Anti‑bacterial activity of mutant chensinin‑1 peptide against multidrug‑resistant Pseudomonas aeruginosa and its effects on biofilm‑associated gene expression

Zhiyuan Yu, Yi Kong, Zhenqin Luo, Tongtong Liu, Jinguan Lin
Pages: 2031-2038
Published online on: 17 January 2019

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Article Open Access

Candidate genes associated with the effect of rosiglitazone on glycemic control and cardiovascular system in the treatment of type 2 diabetes mellitus

Xiaoli Wu
Pages: 2039-2046
Published online on: 09 January 2019

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Value analysis of CD69 combined with EGR1 in the diagnosis of coronary heart disease

Jianqiao Peng, Yi Xiang
Pages: 2047-2052
Published online on: 15 January 2019

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B‑cell activating factor receptor expression is associated with germinal center B‑cell maintenance

Francisco Josué Carrillo‑Ballesteros, Edith Oregon‑Romero, Ramon Antonio Franco‑Topete, Luis Humberto Govea‑Camacho, Alvaro Cruz, José Francisco Muñoz‑Valle, Felipe Jesús Bustos‑Rodríguez, Ana Laura Pereira‑Suárez, Claudia Azucena Palafox‑Sánchez
Pages: 2053-2060
Published online on: 15 January 2019

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E‑cadherin regulates biological behaviors of neural stem cells and promotes motor function recovery following spinal cord injury

Dong Chen, Siyuan Hu, Jie Liu, Shaohua Li
Pages: 2061-2070
Published online on: 15 January 2019

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Effect of baicalin on renal function in patients with diabetic nephropathy and its therapeutic mechanism

Mingzheng Yang, Lin Kan, Lianye Wu, Yingchun Zhu, Qing Wang
Pages: 2071-2076
Published online on: 17 January 2019

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Downregulation of microRNA‑374a predicts poor prognosis in human glioma

Qiang Dong, Guoqiang Yuan, Min Liu, Qiqi Xie, Jianhong Hu, Maolin Wang, Shangyu Liu, Xiaojun Ma, Yawen Pan
Pages: 2077-2084
Published online on: 21 January 2019

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Predicting the target genes of miRNAs in preterm via targetscore algorithm

Kexin Lu, Junzhi Huang, Yandong Yang, Dongli Lu
Pages: 2085-2090
Published online on: 16 January 2019

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Berberine attenuates hepatic oxidative stress in rats with non‑alcoholic fatty liver disease via the Nrf2/ARE signalling pathway

Yuanjun Deng, Kairui Tang, Runsen Chen, Huan Nie, Shu Liang, Jinwen Zhang, Yupei Zhang, Qinhe Yang
Pages: 2091-2098
Published online on: 28 January 2019

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Protective effect of remote ischemic pre‑conditioning on patients undergoing cardiac bypass valve replacement surgery: A randomized controlled trial

Xiuling Jin, Liangrong Wang, Liling Li, Xiyue Zhao
Pages: 2099-2106
Published online on: 21 January 2019

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Prediction of pivotal pathways and hub genes associated with osteoporosis by Gibbs sampling

Yiyun Tan, Lei Liu
Pages: 2107-2112
Published online on: 16 January 2019

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Identification of key transcription factors - gene regulatory network related with osteogenic differentiation of human mesenchymal stem cells based on transcription factor prognosis system

Xuefeng Kang, Yong Sun, Zhao Zhang
Pages: 2113-2122
Published online on: 14 January 2019

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VEGF and sFLT-1 in serum of PIH patients and effects on the foetus

Yanhong Tang, Wenfeng Ye, Xia Liu, Yan Lv, Changfang Yao, Jiang Wei
Pages: 2123-2128
Published online on: 18 January 2019

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Screening of miRNA target genes in coronary artery disease by variational Bayesian Gaussian mixture model

Xiao‑Lin Ma, Xu Yang, Rui Fan
Pages: 2129-2136
Published online on: 22 January 2019

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Therapeutic effects of rituximab combined with cyclophosphamide on refractory idiopathic thrombocytopenic purpura

Jiuhe Wang, Bin Wang, Zhonghui Sun, Kezeng Xue
Pages: 2137-2142
Published online on: 23 January 2019

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Apurinic/apyrimidinic endonuclease/redox factor 1 (APE1) alleviates myocardial hypoxia‑reoxygenation injury by inhibiting oxidative stress and ameliorating mitochondrial dysfunction

Jie Hao, Hong Du, Fan Liu, Jing‑Chao Lu, Xiu‑Chun Yang, Wei Cui
Pages: 2143-2151
Published online on: 29 January 2019

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MicroRNA‑144 attenuates cardiac ischemia/reperfusion injury by targeting FOXO1 Corrigendum in /10.3892/etm.2020.8424

Lusha E, Hong Jiang, Zhibing Lu
Pages: 2152-2160
Published online on: 09 January 2019

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Luteolin improves heart preservation through inhibiting hypoxia‑dependent L‑type calcium channels in cardiomyocytes

Qingfeng Yan, Yueping Li, Jia Yan, Ying Zhao, Yunzhong Liu, Su Liu
Pages: 2161-2171
Published online on: 29 January 2019

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Application of protein chip combined with SELDI‑TOF‑MS detection to investigate serum protein expression in patients with silicosis fibrosis

Guitao Liu, Junfeng Yu, Cuidong Li, Xiaoyun Zhou, Liping Nie, Yanhua Wei, Wenyu Wang, Ying Zhang, Nuziguli Nusilaiti, Ping Hua, Xiaohua Wang, Wenlong Wei, Xinyan Li
Pages: 2172-2184
Published online on: 11 January 2019

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Anti‑obesity effect in high‑fat‑diet‑induced obese C57BL/6 mice: Study of a novel extract from mulberry (Morus alba) leaves fermented with Cordyceps militaris

Mi Rim Lee, Ji Eun Kim, Jun Young Choi, Jin Ju Park, Hye Ryeong Kim, Bo Ram Song, Young Whan Choi, Kyung Mi Kim, Hyunkeun Song, Dae Youn Hwang
Pages: 2185-2193
Published online on: 21 January 2019

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Treatment of Mullerian duct cyst by combination of transurethral resection and seminal vesiculoscopy: An initial experience

Chenkui Miao, Shouyong Liu, Kai Zhao, Jundong Zhu, Ye Tian, Yuhao Wang, Bianjiang Liu, Zengjun Wang
Pages: 2194-2198
Published online on: 25 January 2019

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The treatment of systematically transplanted gingival mesenchymal stem cells in periodontitis in mice

Wendong Sun, Zhiguo Wang, Quanchen Xu, Huibin Sun, Xiaoxuan Liu, Jianjun Yang, Rundan Hong
Pages: 2199-2205
Published online on: 11 January 2019

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Composition and diversity analysis of the B‑cell receptor immunoglobulin heavy chain complementarity‑determining region 3 repertoire in patients with acute rejection after kidney transplantation using high‑throughput sequencing

Liusheng Lai, Xianqing Zhou, Huaizhou Chen, Yadan Luo, Weiguo Sui, Jiaxing Zhang, Donge Tang, Qiang Yan, Yong Dai
Pages: 2206-2220
Published online on: 17 January 2019

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Role of microRNA‑150‑5p/SRCIN1 axis in the progression of breast cancer

Qingfu Lu, Zhaoji Guo, Haixin Qian
Pages: 2221-2229
Published online on: 28 January 2019

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The effects of simvastatin preconditioning on the expression of caspase-3 after myocardial ischemia reperfusion injury in rats

Weixin Sun, Renyou Pan, Jun Song, Honglin Sun
Pages: 2230-2234
Published online on: 09 January 2019

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MicroRNA‑708‑5p affects proliferation and invasion of osteosarcoma cells by targeting URGCP

Cong Sui, Debao Liu, Yong Hu, Linlin Zhang
Pages: 2235-2241
Published online on: 15 January 2019

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Resveratrol suppresses proliferation and induces apoptosis of uterine sarcoma cells by inhibiting the Wnt signaling pathway

Ayuka Mineda, Masato Nishimura, Tomohiro Kagawa, Eri Takiguchi, Takako Kawakita, Akiko Abe, Minoru Irahara
Pages: 2242-2246
Published online on: 28 January 2019

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Efficacy of bone marrow mesenchymal stem cell transplantation in animal models of pulmonary fibrosis after exposure to bleomycin: A meta‑analysis

Enguo Zhang, Ye Yang, Juan Zhang, Guoyong Ding, Shangya Chen, Cheng Peng, Martin F. Lavin, Abrey J. Yeo, Zhongjun Du, Hua Shao
Pages: 2247-2255
Published online on: 28 January 2019

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Chrysin protects against renal ischemia reperfusion induced tubular cell apoptosis and inflammation in mice

Mingwei Xu, Hongbo Shi, Dongcao Liu
Pages: 2256-2262
Published online on: 21 January 2019

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Article Open Access

Intraoperative and postoperative effects of TEG-guided platelet transfusion on antiplateletdrug-related intracerebral hemorrhage patients

Hao Zhou, Li Chen, Hongtian He
Pages: 2263-2267
Published online on: 14 January 2019

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Differential composition of gut microbiota among healthy volunteers, morbidly obese patients and post‑bariatric surgery patients

Fu‑Gang Wang, Ri‑Xing Bai, Wen‑Mao Yan, Ming Yan, Ling‑Yue Dong, Mao‑Min Song
Pages: 2268-2278
Published online on: 25 January 2019

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Analysis of expression levels of IL-17 and IL-34 and influencing factors for prognosis in patients with lupus nephritis

Yanna Cheng, Xiaojuan Yang, Xijun Zhang, Zhi An
Pages: 2279-2283
Published online on: 14 January 2019

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MicroRNA‑205‑5p regulates extracellular matrix production in hyperplastic scars by targeting Smad2

Jun Qi, Yifei Liu, Kesu Hu, Yi Zhang, Yangyang Wu, Xia Zhang
Pages: 2284-2290
Published online on: 21 January 2019

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Effect of HIFU on endometrial receptivity and sex hormone level in uterine fibroid patients and analysis of influencing factors for its treatment rate

Yongmei Cui, Yanyan Dong, Bingcheng Guo, Cuihong Xing, Xiaohui Gao, Dexing Su
Pages: 2291-2297
Published online on: 22 January 2019

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Crosstalk analysis of dysregulated pathways in preeclampsia

Tao Wang, Xing-Zhen Shi, Wen-Hua Wu
Pages: 2298-2304
Published online on: 16 January 2019

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Treatment of patients with systemic‑onset juvenile idiopathic arthritis with tacrolimus

Dongdong Wang, Xiao Chen, Zhiping Li
Pages: 2305-2309
Published online on: 15 January 2019

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Article Open Access

Microvesicles containing miR-34a induce apoptosis of proximal tubular epithelial cells and participate in renal interstitial fibrosis

Hongyan Li, Yuexia Xu, Qin Zhang, Hongfang Xu, Yan Xu, Kai Ling
Pages: 2310-2316
Published online on: 24 January 2019

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Article Open Access

Acetazolamide attenuates cardiac fibrosis induced by aortic constriction through inhibiting transforming growth factor-β1/Smad2 signaling pathway in mice

Qianqian Huo, Ting Wang, Tao Wang, Rui Zhang
Pages: 2317-2321
Published online on: 28 January 2019

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Article Open Access

A clinically relevant blunt spinal cord injury model in the regeneration competent axolotl (Ambystoma mexicanum) tail

Mathias Møller Thygesen, Henrik Lauridsen, Michael Pedersen, Dariusz Orlowski, Trine Werenberg Mikkelsen, Mikkel Mylius Rasmussen
Pages: 2322-2328
Published online on: 21 January 2019

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Article

α‑lipoic acid attenuates spatial learning and memory impairment induced by hepatectomy

Yuan Zhang, Yun‑Luo Lv, Yan‑Na Si, Jianwei Zhou, Yanning Qian, Hong‑Guang Bao
Pages: 2329-2333
Published online on: 25 January 2019

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Article

Inhibition of NET‑1 suppresses proliferation and promotes apoptosis of hepatocellular carcinoma cells by activating the PI3K/AKT signaling pathway

Xiangjun Sun, Mingchun Wang, Fenghua Zhang, Xiao Kong
Pages: 2334-2340
Published online on: 29 January 2019

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Article

Aggravated mucosal and immune damage in a mouse model of ulcerative colitis with stress

Yanxia Gong, Wei Niu, Yanping Tang, Qingyu Zhang, Simiao Liu, Xi Liu, Xiao Wang, Yang Xu
Pages: 2341-2348
Published online on: 09 January 2019

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Article

Mitochondrial separation protein inhibitor inhibits cell apoptosis in rat lungs during intermittent hypoxia

Dan Zhao, Chen‑Yi Yin, Xian‑Wei Ye, Zi‑Fen Wan, De‑Gang Zhao, Xiang‑Yan Zhang
Pages: 2349-2358
Published online on: 25 January 2019

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Article

miR‑212 regulated by HIF‑1α promotes the progression of pancreatic cancer

Hui Yue, Lin Liu, Zhenguo Song
Pages: 2359-2365
Published online on: 29 January 2019

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Article

Role and mechanism of nursing cooperation and tetramethylpyrazine application in post‑operative pain in patients undergoing total knee arthroplasty

Chang Liu, Rui Liu, Meiling Tang, Xinxin Yang, Xiuping Gong
Pages: 2366-2372
Published online on: 25 January 2019

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Article

Oestrogen inhibits PTPRO to prevent the apoptosis of renal podocytes

Wei Ren, Huiru Yi, Ying Bao, Yingru Liu, Xinru Gao
Pages: 2373-2380
Published online on: 14 January 2019

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Article

Cilostazol protects rats against alcohol‑induced hepatic fibrosis via suppression of TGF‑β1/CTGF activation and the cAMP/Epac1 pathway

Kun Han, Yanting Zhang, Zhenwei Yang
Pages: 2381-2388
Published online on: 28 January 2019

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Article

Evaluation of efficacy and nephrotoxicity during vancomycin therapy: A retrospective study in China

Liping Wang, Qing Yuan, Min Tan, Shuanshuan Xie, Jufang Wu, Xiaolian Song, Changhui Wang
Pages: 2389-2396
Published online on: 21 January 2019

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Article

Epidermal growth factor treatment has protective effects on the integrity of the blood‑brain barrier against cerebral ischemia injury in bEnd3 cells

Shu Yang, Hong Jin, Zhi‑Gang Zhao
Pages: 2397-2402
Published online on: 21 January 2019

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May-2026 Volume 31 Issue 5

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FCER1G: A multifunctional regulator in the immune microenvironment (Review)

Yuyu Zhang, Jinglan Wang, Wenting He, Tao Liu
Article Number: 146
Published online on: 26 March 2026

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A nomogram for predicting recurrence‑free survival in patients with high‑risk GIST receiving adjuvant imatinib: A nationwide registry study

Chun-Nan Yeh, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh, Li-Yaun Bai, Jun-Te Hsu, I-Shu Chen, Li-Tzong Chen, Hui-Jen Tsai, The Taiwan Cooperative Oncology Group Gist Study Group
Article Number: 145
Published online on: 24 March 2026

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[Retracted] MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 144
Published online on: 23 March 2026

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Risk factors for severe retinopathy of prematurity: A retrospective case‑control study

Qingmin Ma, Xi Lv, Jiangya Wang, Kejun Li, Wenwen Τang
Article Number: 143
Published online on: 20 March 2026

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Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial

Dawei Wang, Jingya Dai, Shumei Li, Yaping Liu, Xiaofeng Xing, Lei Huang, Qijun Pang
Article Number: 142
Published online on: 19 March 2026

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Maresin 1 activates autophagy through SIRT1/PPAR‑γ signaling to mitigate high glucose‑induced pyroptosis in human retinal pigment epithelial cells

Jun Zhang, Ding Zhao, Yuanqing Zhang, Haoxiang Sun, Zhipeng Yan, Haiyan Sun
Article Number: 141
Published online on: 19 March 2026

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Advances in new ultrasound technologies in targeted prostate biopsy (Review)

Tingting Jin, Liying Wang, Shusen Zheng
Article Number: 140
Published online on: 19 March 2026

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Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review)

Min Liu, Kui Su
Article Number: 139
Published online on: 19 March 2026

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Immunohistochemical evaluation of gastric‑type markers in primary extramammary Paget disease: Differential MUC5AC expression between in situ and invasive lesions

Naoto Kohno, Mitsuaki Ishida, Shizuka Ono, Yoshinobu Hirose
Article Number: 138
Published online on: 19 March 2026

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Disrupted beginnings: Neurodevelopmental outcomes of COVID‑19 lockdowns in early childhood (Review)

Ioanna Giannopoulou, Vasiliki Efstathiou, Maria-Ioanna Stefanou, Panagiota Korkoliakou, James N. Tsoporis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 137
Published online on: 16 March 2026

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[Retracted] Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF‑κB and PI3K/AKT pathways

Ling Sun, Jing Zhang
Article Number: 136
Published online on: 16 March 2026

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Effects of fullerenol C60 on the liver, heart and brain tissues of streptozotocin‑induced diabetic rats with sepsis

Necmiye Şengel, Ömer Kubat, Laman Farajsoylu, Ahmet Çağri Büyükkasap, Muharrem Atli, Şaban Cem Sezen, Hasan Bostanci, Kürşat Dikmen, Işin Güneş, Fatma Er, Mustafa Kavutçu, Mustafa Arslan
Article Number: 135
Published online on: 13 March 2026

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Long non‑coding RNA KCNQ1OT1 promotes ovarian cancer cell malignant characteristics by targeting the miR‑140‑5p/KLK10 axis

Renjie Duan, Zhenyu Tao, Shun Tao, Aichen Yang, Xu Yang, Changzheng Li, Xiaoxiang Zhu, Kexin Zhang, Zhuofu Li, Shanjun Tao
Article Number: 134
Published online on: 11 March 2026

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Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
Published online on: 09 March 2026

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Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
Published online on: 09 March 2026

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Case Report Open Access

Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
Published online on: 06 March 2026

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Case Report

Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report

Yajun Yao, Ge-Hong Dong, De-Cai Tian
Article Number: 129
Published online on: 06 March 2026

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Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta‑analysis

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 128
Published online on: 06 March 2026

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Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Case Report

Management after two consecutive suction losses during small‑incision lenticule extraction: A case report

Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
Published online on: 03 March 2026

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Hematemesis resulting from mesenteric venous thrombosis: A case report

Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
Article Number: 125
Published online on: 02 March 2026

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Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Article

Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
Published online on: 27 February 2026

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A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review)

Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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June-2026 Volume 31 Issue 6

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Factors affecting central sensitization inventory score before surgery for distal radius fractures

Shoichiro Ishii, Kiyohito Naito, Norizumi Imazu, Takamaru Suzuki, Kenjiro Kawamura, So Kawakita, Tatsuki Itoh, Muneaki Ishijima
Article Number: 162
Published online on: 09 April 2026

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Systemic immune‑inflammation index and neutrophil‑to‑lymphocyte ratio predict treatment responses in elderly patients with profound sudden deafness

Chong Li, Huili Wu, Hongxia Cui, Yue Li, Zhiming Sun, Siqi Haoliu, Xinfa Wei
Article Number: 161
Published online on: 09 April 2026

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Efficacy analysis of percutaneous cannulated paravertebral approach for microscopic resection of intraspinal schwannomas: A case series

Shaobo Yang, Nianhua Wang
Article Number: 160
Published online on: 09 April 2026

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3D‑printed customized semi‑restrictive elbow prosthesis for severe pseudoarthritis following comminuted fractures of the distal humerus: A case report and review

Bo Zheng, Xiu-Li Zhang, Yu-Xiang Cheng, Ze-Bi He, Peng Li
Article Number: 159
Published online on: 09 April 2026

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α‑tocopherol in the prevention of ischemic or hemorrhagic stroke: A meta‑analysis

Peng Xu, Pengfei Cheng
Article Number: 158
Published online on: 09 April 2026

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Preliminary study on symptoms and signs of patients with laryngopharyngeal reflux disease infected with Helicobacter pylori

Haixiang Zhang, Huanhuan Dang, Xin Wang, Yuxiang Zhao, Jinping Wang
Article Number: 157
Published online on: 09 April 2026

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Autophagy‑epithelial‑mesenchymal transition crosstalk in acute respiratory distress syndrome: Mechanistic insights and therapeutic perspectives (Review)

Yue Zhang, Hongzhi He, Chufan Dong, Qing Guo, Jiuwen Tan, Yonggui Yang, Zhuangbo Guo, Rui Zhang
Article Number: 156
Published online on: 08 April 2026

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Analysis of low‑benefit subgroups in breast‑conserving surgery: Implications for clinical decision‑making (Review)

Weicheng Lin, Lan Luo, Guiping Guo, Huan Lin
Article Number: 155
Published online on: 08 April 2026

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Case Report

Plexiform fibromyxoma of the lesser curvature of the stomach in a 16‑year‑old adolescent: A case report and literature review

Zhenhua Fu, Peiyao Tao, Da Sun, Xiang Chen
Article Number: 154
Published online on: 08 April 2026

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Retroperitoneal ovarian venous hemangioma: A case report

Jie Tian, Hong Hu, Siyi Chen, Junping Li
Article Number: 153
Published online on: 08 April 2026

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Retraction Open Access

[Retracted] MicroRNA‑140‑5p regulates the proliferation, apoptosis and inflammation of RA FLSs by repressing STAT3

Jiehua Zhu, Jianglin Wang, Jialin Huang, Wensheng Du, Yingzhong He, Hongfei Pan, Junmin Luo
Article Number: 152
Published online on: 07 April 2026

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Effects of rok1 gene deletion on mitosis in fission yeast at appropriate and stressful temperatures and the molecular mechanisms

Jiayi He, Mengnan Liu, Jiani Xu, Xiang Ding, Yiling Hou
Article Number: 151
Published online on: 02 April 2026

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Therapeutic potential of allicin against viral infections: Mechanisms and safety profile (Review)

Ming-Jun Yu, Yong Zhu, Wei Zhang, Qiao-Ping Xu, Hai-Ming Wang, Zhao Ma
Article Number: 150
Published online on: 02 April 2026

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Interacting proteins of AMPK studied using TurboID proximity labeling technology

Xiaoshan Liu, Jieyu Guo, Qiongyao Wang, Wu Liu, Yan Xue, Shuang Guo, Miao Li
Article Number: 149
Published online on: 02 April 2026

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Multi‑omics analysis of glutamine and fish collagen peptides in alleviating post‑antibiotic Streptococcus pneumoniae injury in feline lung cells

Huasong Bai, Tong Liu, Hengyan Wang, Hongchen Jin, Yunliang Li, Zhanzhong Wang
Article Number: 148
Published online on: 30 March 2026

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[Retracted] MicroRNA‑1236‑3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis

Tingting Meng, Shiman Shen, Cheng Li, Xuehua Liu
Article Number: 147
Published online on: 30 March 2026

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