|
1
|
Gras C, Ratuszny D, Hadamitzky C, Zhang H,
Blasczyk R and Figueiredo C: miR-145 contributes to hypertrophic
scarring of the skin by inducing myofibroblast activity. Mol Med.
21:296–304. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Brown BC, McKenna SP, Siddhi K, McGrouther
DA and Bayat A: The hidden cost of skin scars: Quality of life
after skin scarring. J Plast Reconstr Aesthet Surg. 61:1049–1058.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Aarabi S, Longaker MT and Gurtner GC:
Hypertrophic scar formation following burns and trauma: New
approaches to treatment. PLoS Med. 4:e2342007. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Wang XQ, Song F and Liu YK: Hypertrophic
scar regression is linked to the occurrence of endothelial
dysfunction. PLoS One. 12:e01766812017. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Bartel DP: MicroRNAs: Genomics,
biogenesis, mechanism, and function. Cell. 116:281–297. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Fiedler J, Grönniger E, Pfanne A, Brönneke
S, Schmidt K, Falk CS, Wenck H, Terstegen L, Thum T and Winnefeld
M: Identification of miR-126 as a new regulator of skin ageing. Exp
Dermatol. 26:284–286. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Zhang L, Ge Y and Fuchs E: miR-125b can
enhance skin tumor initiation and promote malignant progression by
repressing differentiation and prolonging cell survival. Genes Dev.
28:2532–2546. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Bi S, Chai L, Yuan X, Cao C and Li S:
MicroRNA-98 inhibits the cell proliferation of human hypertrophic
scar fibroblasts via targeting Col1A1. Biol Res. 50:222017.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Dong S and Sun Y: MicroRNA-22 may promote
apoptosis and inhibit the proliferation of hypertrophic scar
fibroblasts by regulating the mitogen-activated protein kinase
kinase/extracellular signal-regulated kinase/p21 pathway. Exp Ther
Med. 14:3841–3845. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Kwan P, Ding J and Tredget EE: MicroRNA
181b regulates decorin production by dermal fibroblasts and may be
a potential therapy for hypertrophic scar. PLoS One.
10:e01230542015. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Li TJ, Chen YL, Gua CJ, Xue SJ, Ma SM and
Li XD: MicroRNA 181b promotes vascular smooth muscle cells
proliferation through activation of PI3K and MAPK pathways. Int J
Clin Exp Pathol. 8:10375–10384. 2015.PubMed/NCBI
|
|
12
|
Shi ZM, Wang XF, Qian X, Tao T, Wang L,
Chen QD, Wang XR, Cao L, Wang YY, Zhang JX, et al: MiRNA-181b
suppresses IGF-1R and functions as a tumor suppressor gene in
gliomas. RNA. 19:552–560. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
He L, Yao H, Fan LH, Liu L, Qiu S, Li X,
Gao JP and Hao CQ: MicroRNA-181b expression in prostate cancer
tissues and its influence on the biological behavior of the
prostate cancer cell line PC-3. Genet Mol Res. 12:1012–1021. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Zhi F, Wang Q, Deng D, Shao N, Wang R, Xue
L, Wang S, Xia X and Yang Y: MiR-181b-5p downregulates NOVA1 to
suppress proliferation, migration and invasion and promote
apoptosis in astrocytoma. PLoS One. 9:e1091242014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
lyu Z, Mao Z, Wang H, Fang Y, Chen T, Wan
Q, Wang M, Wang N, Xiao J, Wei H, et al: MiR-181b targets
Six2 and inhibits the proliferation of metanephric
mesenchymal cells in vitro. Biochem Biophys Res Commun.
440:495–501. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Honardoust D, Varkey M, Hori K, Ding J,
Shankowsky HA and Tredget EE: Small leucine-rich proteoglycans,
decorin and fibromodulin, are reduced in postburn hypertrophic
scar. Wound Repair Regen. 19:368–378. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kresse H and Schönherr E: Proteoglycans of
the extracellular matrix and growth control. J Cell Physiol.
189:266–274. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Wang P, Liu X, Xu P, Lu J, Wang R and Mu
W: Decorin reduces hypertrophic scarring through inhibition of the
TGF-β1/Smad signaling pathway in a rat osteomyelitis model. Exp
Ther Med. 12:2102–2108. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Honardoust D, Ding J, Varkey M, Shankowsky
HA and Tredget EE: Deep dermal fibroblasts refractory to migration
and decorin-induced apoptosis contribute to hypertrophic scarring.
J Burn Care Res. 33:668–677. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zhang Z, Li XJ, Liu Y, Zhang X, Li YY and
Xu WS: Recombinant human decorin inhibits cell proliferation and
downregulates TGF-beta1 production in hypertrophic scar
fibroblasts. Burns. 33:634–641. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Shi J, Li J, Guan H, Cai W, Bai X, Fang X,
Hu X, Wang Y, Wang H, Zheng Z, et al: Anti-fibrotic actions of
interleukin-10 against hypertrophic scarring by activation of
PI3K/AKT and STAT3 signaling pathways in scar-forming fibroblasts.
PLoS One. 9:e982282014. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2ΔΔCT method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Karkhanis M and Park JI: Sp1 regulates
Raf/MEK/ERK-induced p21CIP1 transcription in
TP53-mutated cancer cells. Cell Signal. 27:479–486. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Lin Z, Zhang C, Zhang M, Xu D, Fang Y,
Zhou Z, Chen X, Qin N and Zhang X: Targeting cadherin-17
inactivates Ras/Raf/MEK/ERK signaling and inhibits cell
proliferation in gastric cancer. PLoS One. 9:e852962014. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ramos JW: The regulation of extracellular
signal-regulated kinase (ERK) in mammalian cells. Int J Biochem
Cell Biol. 40:2707–2719. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Li Y, Kilani RT, Rahmani-Neishaboor E,
Jalili RB and Ghahary A: Kynurenine increases matrix
metalloproteinase-1 and −3 expression in cultured dermal
fibroblasts and improves scarring in vivo. J Invest Dermatol.
134:643–650. 2014. View Article : Google Scholar : PubMed/NCBI
|
