|
1
|
Gensel JC, Donnelly DJ and Popovich PG:
Spinal cord injury therapies in humans: An overview of current
clinical trials and their potential effects on intrinsic CNS
macrophages. Expert Opin Ther Targets. 15:505–518. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Tavares I: Human neural stem cell
transplantation in spinal cord injury models: How far from clinical
application? Stem Cell Res Ther. 4(61)2013.PubMed/NCBI
|
|
3
|
Lu Y and Wang MY: Neural stem cell grafts
for complete spinal cord injury. Neurosurgery. 71:N13–N15. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Pomeshchik Y, Puttonen KA, Kidin I,
Ruponen M, Lehtonen S, Malm T, Åkesson E, Hovatta O and Koistinaho
J: Transplanted human induced pluripotent stem cell-derived neural
progenitor cells do not promote functional recovery of
pharmacologically immunosuppressed mice with contusion spinal cord
injury. Cell Transplant. 24:1799–1812. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Salewski RP, Mitchell RA, Li L, Shen C,
Milekovskaia M, Nagy A and Fehlings MG: Transplantation of induced
pluripotent stem cell-derived neural stem cells mediate functional
recovery following thoracic spinal cord injury through
remyelination of axons. Stem Cells Transl Med. 4:743–754. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Sugai K, Nishimura S, Kato-Negishi M, Onoe
H, Iwanaga S, Toyama Y, Matsumoto M, Takeuchi S, Okano H and
Nakamura M: Neural stem/progenitor cell-laden microfibers promote
transplant survival in a mouse transected spinal cord injury model.
J Neurosci Res. 93:1826–1838. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Gonzalez R, Glaser J, Liu MT, Lane TE and
Keirstead HS: Reducing inflammation decreases secondary
degeneration and functional deficit after spinal cord injury. Exp
Neurol. 184:456–463. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Conti A, Cardali S, Genovese T, Di Paola R
and La Rosa G: Role of inflammation in the secondary injury
following experimental spinal cord trauma. J Neurosurg Sci.
47:89–94. 2003.PubMed/NCBI
|
|
9
|
Machova Urdzikova L, Karova K, Ruzicka J,
Kloudova A, Shannon C, Dubisova J, Murali R, Kubinova S, Sykova E,
Jhanwar-Uniyal M and Jendelova P: The anti-inflammatory compound
curcumin enhances locomotor and sensory recovery after spinal cord
injury in rats by immunomodulation. Int J Mol Sci. 17(pii):
E492015. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Han D, Wu C, Xiong Q, Zhou L and Tian Y:
Anti-inflammatory mechanism of bone marrow mesenchymal stem cell
transplantation in rat model of spinal cord injury. Cell Biochem
Biophys. 71:1341–1347. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Karavelioglu E, Gönül Y, Kokulu S, Hazman
Ö, Bozkurt F, Koçak A and Eser O: Anti-inflammatory and
antiapoptotic effect of interleukine-18 binding protein on the
spinal cord ischemia-reperfusion injury. Inflammation. 37:917–923.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Gao J, Grill RJ, Dunn TJ, Bedi S,
Labastida JA, Hetz RA, Xue H, Thonhoff JR, DeWitt DS, Prough DS, et
al: Human neural stem cell transplantation-mediated alteration of
microglial/macrophage phenotypes after traumatic brain injury. Cell
Transplant. 25:1863–1877. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Pellegatta S, Tunici P, Poliani PL,
Dolcetta D, Cajola L, Colombelli C, Ciusani E, Di Donato S and
Finocchiaro G: The therapeutic potential of neural stem/progenitor
cells in murine globoid cell leukodystrophy is conditioned by
macrophage/microglia activation. Neurobiol Dis. 21:314–323. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Klingener M, Chavali M, Singh J, McMillan
N, Coomes A, Dempsey PJ, Chen EI and Aguirre A: N-cadherin promotes
recruitment and migration of neural progenitor cells from the SVZ
neural stem cell niche into demyelinated lesions. J Neurosci.
34:9590–9606. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Karin M, Lawrence T and Nizet V: Innate
immunity gone awry: Linking microbial infections to chronic
inflammation and cancer. Cell. 124:823–835. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Nakamura E, Sugihara H, Bamba M and
Hattori T: Dynamic alteration of the E-cadherin/catenin complex
during cell differentiation and invasion of undifferentiated-type
gastric carcinomas. J Pathol. 205:349–358. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Ma ZZ, Fan L, Huang JL and Pan XJ: A novel
method to derive and expand mice neural stem cells efficiently
without neuro-sphere formation. Int J Clin Exp Med. 8:12834–12841.
2015.PubMed/NCBI
|
|
19
|
Reynolds BA, Tetzlaff W and Weiss S: A
multipotent EGF-responsive striatal embryonic progenitor cell
produces neurons and astrocytes. J Neurosci. 12:4565–4574. 1992.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Anderson DJ: Stem cells and pattern
formation in the nervous system: The possible versus the actual.
Neuron. 30:19–35. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Bacigaluppi M, Pluchino S,
Peruzzotti-Jametti L, Kilic E, Kilic U, Salani G, Brambilla E, West
MJ, Comi G, Martino G and Hermann DM: Delayed post-ischaemic
neuroprotection following systemic neural stem cell transplantation
involves multiple mechanisms. Brain. 132:2239–2251. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Robert AA, Zamzami M, Sam AE, Al Jadid M
and Al Mubarak S: The efficacy of antioxidants in functional
recovery of spinal cord injured rats: An experimental study. Neurol
Sci. 33:785–791. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ravikumar R, Narayanan S, Baskar S,
Senthil Nagarajan R and Abraham S: Autologous stem cell injection
for spinal cord injury-a clinical study from India. J Stem Cells
Regen Med. 3:24–25. 2007.PubMed/NCBI
|
|
24
|
Seebach C, Henrich D, Meier S, Nau C,
Bonig H and Marzi I: Safety and feasibility of cell-based therapy
of autologous bone marrow-derived mononuclear cells in
plate-stabilized proximal humeral fractures in humans. J Transl
Med. 14:3142016. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Kumar AA, Kumar SR, Narayanan R, Arul K
and Baskaran M: Autologous bone marrow derived mononuclear cell
therapy for spinal cord injury: A phase I/II clinical safety and
primary efficacy data. Exp Clin Transplant. 7:241–248.
2009.PubMed/NCBI
|
|
26
|
Einstein O, Karussis D, Grigoriadis N,
Mizrachi-Kol R, Reinhartz E, Abramsky O and Ben-Hur T:
Intraventricular transplantation of neural precursor cell spheres
attenuates acute experimental allergic encephalomyelitis. Mol Cell
Neurosci. 24:1074–1082. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Pluchino S, Zanotti L, Rossi B, Brambilla
E, Ottoboni L, Salani G, Martinello M, Cattalini A, Bergami A,
Furlan R, et al: Neurosphere-derived multipotent precursors promote
neuroprotection by an immunomodulatory mechanism. Nature.
436:266–271. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Aharonowiz M, Einstein O, Fainstein N,
Lassmann H, Reubinoff B and Ben-Hur T: Neuroprotective effect of
transplanted human embryonic stem cell-derived neural precursors in
an animal model of multiple sclerosis. PLoS One. 3:e31452008.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Cheng Z, Zhu W, Cao K, Wu F, Li J, Wang G,
Li H, Lu M, Ren Y and He X: Anti-inflammatory mechanism of neural
stem cell transplantation in spinal cord injury. Int J Mol Sci.
17(pii): E13802016. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Mautes AE, Weinzierl MR, Donovan F and
Noble LJ: Vascular events after spinal cord injury: Contribution to
secondary pathogenesis. Phys Ther. 80:673–687. 2000.PubMed/NCBI
|
|
31
|
Fleming JC, Norenberg MD, Ramsay DA,
Dekaban GA, Marcillo AE, Saenz AD, Pasquale-Styles M, Dietrich WD
and Weaver LC: The cellular inflammatory response in human spinal
cords after injury. Brain. 129:3249–3269. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Hausmann ON: Post-traumatic inflammation
following spinal cord injury. Spinal Cord. 41:369–378. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Liu Y, Ye H, Satkunendrarajah K, Yao GS,
Bayon Y and Fehlings MG: A self-assembling peptide reduces glial
scarring, attenuates post-traumatic inflammation and promotes
neurological recovery following spinal cord injury. Acta Biomater.
9:8075–8088. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
van Roy F: Beyond E-cadherin: Roles of
other cadherin superfamily members in cancer. Nat Rev Cancer.
14:121–134. 2014. View
Article : Google Scholar : PubMed/NCBI
|
|
35
|
Onder TT, Gupta PB, Mani SA, Yang J,
Lander ES and Weinberg RA: Loss of E-cadherin promotes metastasis
via multiple downstream transcriptional pathways. Cancer Res.
68:3645–3654. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Vleminckx K, Vakaet L Jr, Mareel M, Fiers
W and van Roy F: Genetic manipulation of E-cadherin expression by
epithelial tumor cells reveals an invasion suppressor role. Cell.
66:107–119. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Christofori G and Semb H: The role of the
cell-adhesion molecule E-cadherin as a tumour-suppressor gene.
Trends Biochem Sci. 24:73–76. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Frixen UH, Behrens J, Sachs M, Eberle G,
Voss B, Warda A, Löchner D and Birchmeier W: E-cadherin-mediated
cell-cell adhesion prevents invasiveness of human carcinoma cells.
J Cell Biol. 113:173–185. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Eastham AM, Spencer H, Soncin F, Ritson S,
Merry CL, Stern PL and Ward CM: Epithelial-mesenchymal transition
events during human embryonic stem cell differentiation. Cancer
Res. 67:11254–11262. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
D'Amour KA, Agulnick AD, Eliazer S, Kelly
OG, Kroon E and Baetge EE: Efficient differentiation of human
embryonic stem cells to definitive endoderm. Nat Biotechnol.
23:1534–1541. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Xu Y, Zhu X, Hahm HS, Wei W, Hao E, Hayek
A and Ding S: Revealing a core signaling regulatory mechanism for
pluripotent stem cell survival and self-renewal by small molecules.
Proc Natl Acad Sci USA. 107:8129–8134. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Li L, Wang BH, Wang S, Moalim-Nour L,
Mohib K, Lohnes D and Wang L: Individual cell movement, asymmetric
colony expansion, rho-associated kinase, and E-cadherin impact the
clonogenicity of human embryonic stem cells. Biophys J.
98:2442–2451. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Hao J, Li TG, Qi X, Zhao DF and Zhao GQ:
WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to
prevent differentiation of mouse embryonic stem cells. Dev Biol.
290:81–91. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Hawkins K, Mohamet L, Ritson S, Merry CL
and Ward CM: E-cadherin and, in its absence, N-cadherin promotes
Nanog expression in mouse embryonic stem cells via STAT3
phosphorylation. Stem Cells. 30:1842–1851. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Maeda K, Takemura M, Umemori M and
Adachi-Yamada T: E-cadherin prolongs the moment for interaction
between intestinal stem cell and its progenitor cell to ensure
Notch signaling in adult Drosophila midgut. Genes Cells.
13:1219–1227. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Jin Z, Kirilly D, Weng C, Kawase E, Song
X, Smith S, Schwartz J and Xie T: Differentiation-defective stem
cells outcompete normal stem cells for niche occupancy in the
Drosophila ovary. Cell Stem Cell. 2:39–49. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
del Valle I, Rudloff S, Carles A, Li Y,
Liszewska E, Vogt R and Kemler R: E-cadherin is required for the
proper activation of the Lifr/Gp130 signaling pathway in mouse
embryonic stem cells. Development. 140:1684–1692. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Karpowicz P, Willaime-Morawek S, Balenci
L, DeVeale B, Inoue T and van der Kooy D: E-Cadherin regulates
neural stem cell self-renewal. J Neurosci. 29:3885–3896. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Shie JH and Kuo HC: Higher levels of cell
apoptosis and abnormal E-cadherin expression in the urothelium are
associated with inflammation in patients with interstitial
cystitis/painful bladder syndrome. BJU Int. 108:E136–E141. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Mehta S, Nijhuis A, Kumagai T, Lindsay J
and Silver A: Defects in the adherens junction complex
(E-cadherin/β-catenin) in inflammatory bowel disease. Cell Tissue
Res. 360:749–760. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Zbar AP, Simopoulos C and Karayiannakis
AJ: Cadherins: An integral role in inflammatory bowel disease and
mucosal restitution. J Gastroenterol. 39:413–421. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Turner JR: Molecular basis of epithelial
barrier regulation: From basic mechanisms to clinical application.
Am J Pathol. 169:1901–1909. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Takeichi M: Cadherin cell adhesion
receptors as a morphogenetic regulator. Science. 251:1451–1455.
1991. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Tsai HT, Lee TH, Yang SF, Lin LY, Tee YT
and Wang PH: Markedly elevated soluble E-cadherin in plasma of
patient with pelvic inflammatory disease. Fertil Steril.
99:490–495. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Reiss K, Ludwig A and Saftig P: Breaking
up the tie: Disintegrin-like metalloproteinases as regulators of
cell migration in inflammation and invasion. Pharmacol Ther.
111:985–1006. 2006. View Article : Google Scholar : PubMed/NCBI
|
