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Review

Epidemiology, diagnosis and treatment of moyamoya disease (Review)

  • Authors:
    • Hui Zhang
    • Lijian Zheng
    • Lei Feng
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, The First People's Hospital of Jining, Jining, Shandong 272011, P.R. China
  • Pages: 1977-1984
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    Published online on: January 25, 2019
       https://doi.org/10.3892/etm.2019.7198
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Abstract

Moyamoya disease (MMD) is a type of chronic cerebrovascular occlusion disease, which frequently occurs in East Asian populations, including pediatric and adult patients, and may lead to ischemic or hemorrhagic stroke, headache, epilepsy or transient ischemic attack. To date, the underlying mechanisms of MMD have remained to be fully elucidated, but certain studies have indicated that genetic factors may be an important component of its development. Cerebral angiography is the best approach for diagnosing MMD. However, with technological advances, non‑invasive techniques are increasingly used to accurately evaluate MMD. MMD is commonly treated via surgery, and an increasing number of patients are benefitting from the intra‑ and extra‑cranial revascularization. The present article provides a comprehensive review of MMD on the basis of previous research.
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Copy and paste a formatted citation
Spandidos Publications style
Zhang H, Zheng L and Feng L: Epidemiology, diagnosis and treatment of moyamoya disease (Review). Exp Ther Med 17: 1977-1984, 2019.
APA
Zhang, H., Zheng, L., & Feng, L. (2019). Epidemiology, diagnosis and treatment of moyamoya disease (Review). Experimental and Therapeutic Medicine, 17, 1977-1984. https://doi.org/10.3892/etm.2019.7198
MLA
Zhang, H., Zheng, L., Feng, L."Epidemiology, diagnosis and treatment of moyamoya disease (Review)". Experimental and Therapeutic Medicine 17.3 (2019): 1977-1984.
Chicago
Zhang, H., Zheng, L., Feng, L."Epidemiology, diagnosis and treatment of moyamoya disease (Review)". Experimental and Therapeutic Medicine 17, no. 3 (2019): 1977-1984. https://doi.org/10.3892/etm.2019.7198
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang H, Zheng L and Feng L: Epidemiology, diagnosis and treatment of moyamoya disease (Review). Exp Ther Med 17: 1977-1984, 2019.
APA
Zhang, H., Zheng, L., & Feng, L. (2019). Epidemiology, diagnosis and treatment of moyamoya disease (Review). Experimental and Therapeutic Medicine, 17, 1977-1984. https://doi.org/10.3892/etm.2019.7198
MLA
Zhang, H., Zheng, L., Feng, L."Epidemiology, diagnosis and treatment of moyamoya disease (Review)". Experimental and Therapeutic Medicine 17.3 (2019): 1977-1984.
Chicago
Zhang, H., Zheng, L., Feng, L."Epidemiology, diagnosis and treatment of moyamoya disease (Review)". Experimental and Therapeutic Medicine 17, no. 3 (2019): 1977-1984. https://doi.org/10.3892/etm.2019.7198
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