|
1
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2016. CA Cancer J Clin. 66:7–30. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Rahman R, Asombang AW and Ibdah JA:
Characteristics of gastric cancer in Asia. World J Gastroenterol.
20:4483–4490. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Orditura M, Galizia G, Sforza V,
Gambardella V, Fabozzi A, Laterza MM, Andreozzi F, Ventriglia J,
Savastano B, Mabilia A, et al: Treatment of gastric cancer. World J
Gastroenterol. 20:1635–1649. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Martinou JC, Desagher S and Antonsson B:
Cytochrome c release from mitochondria: All or nothing. Nat Cell
Biol. 2:E41–E43. 2000. View
Article : Google Scholar : PubMed/NCBI
|
|
5
|
Sun Y, Tang XM, Half E, Kuo MT and
Sinicrope FA: Cyclooxygenase-2 overexpression reduces apoptotic
susceptibility by inhibiting the cytochrome c-dependent apoptotic
pathway in human colon cancer cells. Cancer Res. 62:6323–6328.
2002.PubMed/NCBI
|
|
6
|
Siddik ZH: Cisplatin: Mode of cytotoxic
action and molecular basis of resistance. Oncogene. 22:7265–7279.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Wagner AD, Syn NL, Moehler M, Grothe W,
Yong WP, Tai BC, Ho J and Unverzagt S: Chemotherapy for advanced
gastric cancer. Cochrane Database Syst Rev.
8:CD0040642017.PubMed/NCBI
|
|
8
|
Lamonerie T, Tremblay JJ, Lanctôt C,
Therrien M, Gauthier Y and Drouin J: Ptx1, a bicoid-related homeo
box transcription factor involved in transcription of the
pro-opiomelanocortin gene. Genes Dev. 10:1284–1295. 1996.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
DeLaurier A, Schweitzer R and Logan M:
Pitx1 determines the morphology of muscle, tendon, and bones of the
hindlimb. Dev Biol. 299:22–34. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Shang J, Li X, Ring HZ, Clayton DA and
Francke U: Backfoot, a novel homeobox gene, maps to human
chromosome 5 (BFT) and mouse chromosome 13 (Bft). Genomics.
40:108–113. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Shang J, Luo Y and Clayton DA: Backfoot is
a novel homeobox gene expressed in the mesenchyme of developing
hind limb. Dev Dyn. 209:242–253. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Kolfschoten IG, van Leeuwen B, Berns K,
Mullenders J, Beijersbergen RL, Bernards R, Voorhoeve PM and Agami
R: A genetic screen identifies PITX1 as a suppressor of RAS
activity and tumorigenicity. Cell. 121:849–858. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Libório TN, Acquafreda T,
Matizonkas-Antonio LF, Silva-Valenzuela MG, Ferraz AR and Nunes FD:
In situ hybridization detection of homeobox genes reveals distinct
expression patterns in oral squamous cell carcinomas.
Histopathology. 58:225–233. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Lord RV, Brabender J, Wickramasinghe K,
DeMeester SR, Holscher A, Schneider PM, Danenberg PV and DeMeester
TR: Increased CDX2 and decreased PITX1 homeobox gene expression in
Barrett's esophagus and Barrett's-associated adenocarcinoma.
Surgery. 138:924–931. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Chen YN, Chen H, Xu Y, Zhang X and Luo Y:
Expression of pituitary homeobox 1 gene in human gastric
carcinogenesis and its clinicopathological significance. World J
Gastroenterol. 14:292–297. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Qi DL, Ohhira T, Fujisaki C, Inoue T, Ohta
T, Osaki M, Ohshiro E, Seko T, Aoki S, Oshimura M and Kugoh H:
Identification of PITX1 as a TERT suppressor gene located on human
chromosome 5. Mol Cell Biol. 31:1624–1636. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Chen Y, Knösel T, Ye F, Pacyna-Gengelbach
M, Deutschmann N and Petersen I: Decreased PITX1 homeobox gene
expression in human lung cancer. Lung Cancer. 55:287–294. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Stender JD, Stossi F, Funk CC, Charn TH,
Barnett DH and Katzenellenbogen BS: The estrogen-regulated
transcription factor PITX1 coordinates gene-specific regulation by
estrogen receptor-alpha in breast cancer cells. Mol Endocrinol.
25:1699–1709. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Calvisi DF, Ladu S, Conner EA, Seo D,
Hsieh JT, Factor VM and Thorgeirsson SS: Inactivation of Ras
GTPase-activating proteins promotes unrestrained activity of
wild-type Ras in human liver cancer. J Hepatol. 54:311–319. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Knösel T, Chen Y, Hotovy S, Settmacher U,
Altendorf-Hofmann A and Petersen I: Loss of desmocollin 1–3 and
homeobox genes PITX1 and CDX2 are associated with tumor progression
and survival in colorectal carcinoma. Int J Colorectal Dis.
27:1391–1399. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Hamidov Z, Altendorf-Hofmann A, Chen Y,
Settmacher U, Petersen I and Knösel T: Reduced expression of
desmocollin 2 is an independent prognostic biomarker for shorter
patients survival in pancreatic ductal adenocarcinoma. J Clin
Pathol. 64:990–994. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Kwok SC, Liu X, Mangel P and Daskal I:
PTX1(ERGIC2)-VP22 fusion protein upregulates interferon-beta in
prostate cancer cell line PC-3. DNA Cell Biol. 25:523–529. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Osaki M, Chinen H, Yoshida Y, Ohhira T,
Sunamura N, Yamamoto O, Ito H, Oshimura M and Kugoh H: Decreased
PITX1 gene expression in human cutaneous malignant melanoma and its
clinicopathological significance. Eur J Dermatol. 23:344–349.
2013.PubMed/NCBI
|
|
24
|
Kong G, Liu Z, Wu K, Zhang Y, Deng Z, Feng
W, Chen S and Wang H: Strong expression of paired-like homeodomain
transcription factor 1 (PITX1) is associated with a favorable
outcome in human osteosarcoma. Tumour Biol. 36:7735–7741. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Nakabayashi M, Osaki M, Kodani I, Okada F,
Ryoke K, Oshimura M, Ito H and Kugoh H: PITX1 is a reliable
biomarker for predicting prognosis in patients with oral epithelial
dysplasia. Oncol Lett. 7:750–754. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Takenobu M, Osaki M, Fujiwara K, Fukuhara
T, Kitano H, Kugoh H and Okada F: PITX1 is a novel predictor of the
response to chemotherapy in head and neck squamous cell carcinoma.
Mol Clin Oncol. 5:89–94. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Kanehisa M, Sato Y, Kawashima M, Furumichi
M and Tanabe M: KEGG as a reference resource for gene and protein
annotation. Nucleic Acids Res. 44:D457–D462. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Qiao F, Gong P, Song Y, Shen X, Su X, Li
Y, Wu H, Zhao Z and Fan H: Downregulated PITX1 modulated by
MiR-19a-3p promotes cell malignancy and predicts a poor prognosis
of gastric cancer by affecting transcriptionally activated PDCD5.
Cell Physiol Biochem. 46:2215–2231. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Klopocki E, Kähler C, Foulds N, Shah H,
Joseph B, Vogel H, Lüttgen S, Bald R, Besoke R, Held K, et al:
Deletions in PITX1 cause a spectrum of lower-limb malformations
including mirror-image polydactyly. Eur J Hum Genet. 20:705–708.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Infante CR, Park S, Mihala AG, Kingsley DM
and Menke DB: Pitx1 broadly associates with limb enhancers and is
enriched on hindlimb cis-regulatory elements. Dev Biol.
374:234–244. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Gajewska A, Herman AP, Wolinska-Witort E,
Kochman K and Zwierzchowski L: In vivo oestrogenic modulation of
Egr1 and Pitx1 gene expression in female rat pituitary gland. J Mol
Endocrinol. 53:355–366. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Longley DB, Harkin DP and Johnston PG:
5-fluorouracil: Mechanisms of action and clinical strategies. Nat
Rev Cancer. 3:330–338. 2003. View
Article : Google Scholar : PubMed/NCBI
|
|
34
|
Marullo R, Werner E, Degtyareva N, Moore
B, Altavilla G, Ramalingam SS and Doetsch PW: Cisplatin induces a
mitochondrial-ROS response that contributes to cytotoxicity
depending on mitochondrial redox status and bioenergetic functions.
PLoS One. 8:e811622013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Ozols RF, Bookman MA, du Bois A, Pfisterer
J, Reuss A and Young RC: Intraperitoneal cisplatin therapy in
ovarian cancer: Comparison with standard intravenous carboplatin
and paclitaxel. Gynecol Oncol. 103:1–6. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Burger AM, Double JA and Newell DR:
Inhibition of telomerase activity by cisplatin in human testicular
cancer cells. Eur J Cancer. 33:638–644. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Kies MS, Rosen ST, Tsang TK, Shetty R,
Schneider PA, Wallemark CB and Shields TW: Cisplatin and
5-fluorouracil in the primary management of squamous esophageal
cancer. Cancer. 60:2156–2160. 1987. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Declercq W, Vanden Berghe T and
Vandenabeele P: RIP kinases at the crossroads of cell death and
survival. Cell. 138:229–232. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Fuchs Y and Steller H: Programmed cell
death in animal development and disease. Cell. 147:742–758. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Kantari C and Walczak H: Caspase-8 and
bid: Caught in the act between death receptors and mitochondria.
Biochim Biophys Acta. 1813:558–563. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Zhang X, Fan C and Zhang H, Zhao Q, Liu Y,
Xu C, Xie Q, Wu X, Yu X, Zhang J and Zhang H: MLKL and FADD are
critical for suppressing progressive lymphoproliferative disease
and activating the NLRP3 inflammasome. Cell Rep. 16:3247–3259.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Oliver Metzig M, Fuchs D, Tagscherer KE,
Gröne HJ, Schirmacher P and Roth W: Inhibition of caspases primes
colon cancer cells for 5-fluorouracil-induced TNF-α-dependent
necroptosis driven by RIP1 kinase and NF-κB. Oncogene.
35:3399–3409. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Ratovitski EA: Phospho-ΔNp63α-responsive
microRNAs contribute to the regulation of necroptosis in squamous
cell carcinoma upon cisplatin exposure. FEBS Lett. 589:1352–1358.
2015. View Article : Google Scholar : PubMed/NCBI
|
