A paediatric influenza update 100 years after the Skyros island Spanish flu outbreak

Mammas,Ioannis  N.; Theodoridou,Maria; Thiagarajan,Prakash; Melidou,Angeliki; Papaioannou,Georgia; Korovessi,Paraskevi; Koutsaftiki,Chryssie; Papatheodoropoulou,Alexia; Calachanis,Marcos; Dalianis,Tina; Spandidos,Demetrios  A.

doi:10.3892/etm.2019.7515

A paediatric influenza update 100 years after the Skyros island Spanish flu outbreak

Authors:
- Ioannis N. Mammas
- Maria Theodoridou
- Prakash Thiagarajan
- Angeliki Melidou
- Georgia Papaioannou
- Paraskevi Korovessi
- Chryssie Koutsaftiki
- Alexia Papatheodoropoulou
- Marcos Calachanis
- Tina Dalianis
- Demetrios A. Spandidos
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Affiliations: Department of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece, First Department of Paediatrics, ‘Aghia Sophia’ Children's Hospital, University of Athens School of Medicine, 115 27 Athens, Greece, Neonatal Unit, Division for Women's & Children Health, Noble's Hospital, IM4 4RJ Douglas, Isle of Man, British Isles, Second Laboratory of Microbiology, School of Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece, Department of Paediatric Radiology, ‘Mitera’ Children's Hospital, 151 23 Athens, Greece, Department of Paediatrics, ‘Penteli’ Children's Hospital, 152 36 Penteli, Greece, Paediatric Intensive Care Unit (PICU), ‘Penteli’ Children's Hospital, 152 36 Penteli, Greece, Paediatric Intensive Care Unit (PICU), ‘P. and A. Kyriakou’ Children's Hospital, 115 27 Athens, Greece, Department of Paediatric Cardiology, ‘Penteli’ Children's Hospital, 152 36 Penteli, Greece, Karolinska Institutet, Karolinska University Hospital, SE-117 77 Stockholm, Sweden
Published online on: April 22, 2019 https://doi.org/10.3892/etm.2019.7515
Pages: 4327-4336
Copyright: © Mammas et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

This year marks the 100th anniversary of the 1918 Spanish flu outbreak on the Greek Aegean Sea island of Skyros, which devastated its population in less than 30 days. According to Constantinos Faltaits's annals published in 1919, the influenza attack on the island of Skyros commenced acutely ‘like a thunderbolt’ on the 27th of October, 1918 and was exceptionally severe and fatal. At that time, the viral cause of the influenza had not been detected, while the total number of victims of the Spanish flu outbreak has been estimated to have surpassed 50 million, worldwide. Almost one century after this Aegean Sea island's tragedy, the ‘4th Workshop on Paediatric Virology’, organised on the 22nd of September, 2018 in Athens, Greece, was dedicated to the 100 years of the ‘Spanish’ flu pandemic. This review article highlights the plenary and key lectures presented at the workshop on the recent advances on the epidemiology, clinical management and prevention of influenza in childhood.

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