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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2019 Volume 17 Issue 6

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Editorial Open Access

[Editorial] A literature reference on the 1918 Spanish flu outbreak

Ioannis N. Mammas, Demetrios A. Spandidos
Pages: 4325-4326
Published online on: 22 April 2019

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Article Open Access

A paediatric influenza update 100 years after the Skyros island Spanish flu outbreak

Ioannis N. Mammas, Maria Theodoridou, Prakash Thiagarajan, Angeliki Melidou, Georgia Papaioannou, Paraskevi Korovessi, Chryssie Koutsaftiki, Alexia Papatheodoropoulou, Marcos Calachanis, Tina Dalianis, Demetrios A. Spandidos
Pages: 4327-4336
Published online on: 22 April 2019

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Article Open Access

Paediatric virology and human papillomaviruses: An update

Ioannis N. Mammas, Tina Dalianis, Sotiros G. Doukas, Apostolos Zaravinos, Vassilis Achtsidis, Prakash Thiagarajan, Maria Theodoridou, Demetrios A. Spandidos
Pages: 4337-4343
Published online on: 22 April 2019

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Article Open Access

Xenotransplantation of human dental pulp stem cells in platelet‑rich plasma for the treatment of full‑thickness articular cartilage defects in a rabbit model

Ricardo Hideki Yanasse, Roger William de Lábio, Leonardo Marques, Josianne Tomazini Fukasawa, Rosimeire Segato, Angela Kinoshita, Mariza Akemi Matsumoto, Sergio Luis Felisbino, Bruno Solano, Ricardo Ribeiro dos Santos, Spencer Luiz Marques Payão
Pages: 4344-4356
Published online on: 17 April 2019

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Article Open Access

Design and application of subaxial cervical pedicle screw placement guide device

Qiang Wang, Runlin Xing, Yiwen Zeng
Pages: 4357-4362
Published online on: 11 April 2019

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Article Open Access

miR‑1271 enhances the sensitivity of colorectal cancer cells to cisplatin

Huixiang Yao, Qun Sun, Jinshui Zhu
Pages: 4363-4370
Published online on: 18 April 2019

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Article Open Access

PM2.5 induces cell cycle arrest through regulating mTOR/P70S6K1 signaling pathway

Yu Zhang, Dan Yang, Biao Yang, Bingyu Li, Jie Guo, Chunling Xiao
Pages: 4371-4378
Published online on: 03 April 2019

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Article Open Access

Evaluation of hemodynamics in patients with hypertrophic cardiomyopathy by vector flow mapping: Comparison with healthy subjects

Yuan Cao, Xiao‑Yan Sun, Ming Zhong, Li Li, Mei Zhang, Ming‑Jie Lin, Yu‑Ke Zhang, Gui‑Hua Jiang, Wei Zhang, Yuan‑Yuan Shang
Pages: 4379-4388
Published online on: 19 April 2019

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Article Open Access

Protective effect of gastrodin on myocardial ischemia‑reperfusion injury and the expression of Bax and Bcl‑2

Xiao Han, Hai Shi, Kun Liu, Lou Zhong, Fei Wang, Qingsheng You
Pages: 4389-4394
Published online on: 19 April 2019

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Article Open Access

Performance of Topcon 3D optical coherence tomography‑2000 in re‑analyzing OCT‑1000 raw data

Binyao Chen, Haoyu Chen, Ce Zheng, Mingzhi Zhang
Pages: 4395-4402
Published online on: 12 April 2019

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Article Open Access

Association of Helicobacter pylori infection with metabolic syndrome in aged Chinese females

Yingying Yu, Jianting Cai, Zhenya Song, Jinghua Wang, Lingyan Wu
Pages: 4403-4408
Published online on: 19 April 2019

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Article Open Access

Astragaloside IV ameliorates high glucose‑induced HK‑2 cell apoptosis and oxidative stress by regulating the Nrf2/ARE signaling pathway Retraction in /10.3892/etm.2025.12979

Jing Wang, Hong‑Min Guo
Pages: 4409-4416
Published online on: 17 April 2019

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Article Open Access

Relationship between senile osteoporosis and cardiovascular and cerebrovascular diseases

Xiaoying Hu, Shucan Ma, Caixia Yang, Weiwei Wang, Liman Chen
Pages: 4417-4420
Published online on: 23 April 2019

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Article Open Access

Comparison of the effect and clinical value in general anesthesia and combined spinal-epidural anesthesia in elderly patients undergoing hip arthroplasty

Huanhui Zhong, Yongdong Wang, Yiqun Wang, Baiyun Wang
Pages: 4421-4426
Published online on: 03 April 2019

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Article Open Access

Comparison of efficacy between trimetazidine and cilostazol in the treatment of arteriosclerosis obliterans in lower extremity

Min Hu, Dile Wang, Tao He
Pages: 4427-4434
Published online on: 08 April 2019

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Article Open Access

Expression of miR‑181a and TGF‑β2 in lens epithelial cells of patients with cataractous retinal detachment and its clinical significance

Yanyun Jiang, Yingying Gong, Nan Lin, Wei Qiu
Pages: 4435-4440
Published online on: 16 April 2019

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Article Open Access

Effect of CT manifestations of cholesteatoma on MMP‑2, MMP‑9 and IL‑6 in the serum of patients

Yingzhe Wu, Xiangli Tang, Weifang Shao, Yuezhong Lu
Pages: 4441-4446
Published online on: 12 April 2019

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Article Open Access

Developmental features of DNA methylation in CpG islands of human gametes and preimplantation embryos

Yuling Huang, Haiying Liu, Hongzhi Du, Wenhong Zhang, Xianjing Kang, Yang Luo, Xueliang Zhou, Lei Li
Pages: 4447-4456
Published online on: 23 April 2019

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Article Open Access

Overexpression of TGF‑β enhances the migration and invasive ability of ectopic endometrial cells via ERK/MAPK signaling pathway Retraction in /10.3892/etm.2025.12934

Zhihong Liu, Lisha Yi, Miaomiao Du, Guifang Gong, Yali Zhu
Pages: 4457-4464
Published online on: 23 April 2019

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Article Open Access

Evaluation of ultrasonography on carotid arteries and left ventricular function in patients with subclinical atherosclerosis

Tao Zhang, Haiwei Yin, Hanwen Xue
Pages: 4465-4470
Published online on: 22 April 2019

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Article Open Access

Application value of hypersensitive C-reactive protein, lactic acid and myoglobin in the combined detection of myocarditis

Yang Liu, Xuecheng Huang, Yuanhang Liu, Dongyang Li, Jingchang Zhang, Lihui Yang
Pages: 4471-4476
Published online on: 23 April 2019

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Article Open Access

Inhibitory effect of simvastatin in nasopharyngeal carcinoma cells

Zhaoxin Ma, Weihua Wang, Yu Zhang, Min Yao, Liyun Ying, Liwei Zhu
Pages: 4477-4484
Published online on: 23 April 2019

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Article Open Access

Detection of melanocyte lineage‑specific genes in vitiligo lesions

Wanwen Xu, Xiong Wang
Pages: 4485-4491
Published online on: 17 April 2019

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Article Open Access

Dose‑related histopathology and bone remodeling characteristics of the knee articular cartilage and subchondral bone induced by glucocorticoids in rats

Yan Chen, Lian‑Fang Huang, Jue‑Xin Zhu
Pages: 4492-4498
Published online on: 19 April 2019

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Article Open Access

Expression and clinical value of CD105 in renal cell carcinoma based on data mining in The Cancer Genome Atlas

Donghui Shi, Jianping Che, Yang Yan, Bo Peng, Xudong Yao, Changcheng Guo
Pages: 4499-4505
Published online on: 17 April 2019

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Article Open Access

A prognostic prediction system for hepatocellular carcinoma based on gene co‑expression network

Lianyue Guan, Qiang Luo, Na Liang, Hongyu Liu
Pages: 4506-4516
Published online on: 17 April 2019

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Article Open Access

Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice

Changbo Deng, Juan Li, Luyi Li, Fengjie Sun, Jiqing Xie
Pages: 4517-4521
Published online on: 15 April 2019

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Article Open Access

Investigation of expression and effects of TGF‑β1 and MMP‑9 in lens epithelial cells of diabetic cataract rats

Ke Li, Wei Ai
Pages: 4522-4526
Published online on: 08 April 2019

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Article Open Access

Risk stratification and prognostic evaluation of endothelial cell‑specific molecule1, von Willebrand factor, and a disintegrin‑like and metalloprotease with thrombospondin type 1 motif for sepsis in the emergency department: An observational study

Qing Zhang, Chun‑Sheng Li
Pages: 4527-4535
Published online on: 15 April 2019

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Article Open Access

Abnormal expression and mutation of the RBPJ gene may be involved in CD59‑ clonal proliferation in paroxysmal nocturnal hemoglobinuria

Liyan Li, Hui Liu, Honglei Wang, Zhaoyun Liu, Yingying Chen, Lijuan Li, Jia Song, Guojin Wang, Rong Fu
Pages: 4536-4546
Published online on: 10 April 2019

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Article

BAY 87‑2243 sensitizes hepatocellular carcinoma Hep3B cells to histone deacetylase inhibitors treatment via GSK‑3β activation

Yang‑Ling Li, Ming‑Jun Rao, Ning‑Yu Zhang, Lin‑Wen Wu, Neng‑Ming Lin, Chong Zhang
Pages: 4547-4553
Published online on: 18 April 2019

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Article Open Access

Efficacy of trimetazidine and plasmin combined with alprostadil in treatment of lower extremity arteriosclerosis obliterans

Jun Yong, Yingchun Wang, Shouli Xing, Yufang Bi, Ning Li, Shanna Zhao
Pages: 4554-4560
Published online on: 10 April 2019

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Article Open Access

Comparison of desflurane and sevoflurane on postoperative recovery quality after tonsillectomy and adenoidectomy in children

Xiaole Wu, Chengjing Shan, Bei Peng, Xuxu Shi, Fengchao Zhang, Junhua Cao
Pages: 4561-4567
Published online on: 04 April 2019

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Article Open Access

Emerging Gram‑positive bacteria and drug resistance in cirrhosis patients with spontaneous bacterial peritonitis: A retrospective study

Jingjing Guo, Jingren Shi, Huizhu Wang, Hui Chen, Shunai Liu, Junnan Li, Yajie Wang
Pages: 4568-4576
Published online on: 18 April 2019

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Article Open Access

MicroRNA‑10b‑5p downregulation inhibits the invasion of glioma cells via modulating homeobox B3 expression

Weiling Li, Chaoying Li, Qi Xiong, Xiang Tian, Qin Ru
Pages: 4577-4585
Published online on: 19 April 2019

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Article Open Access

Application value of procalcitonin, C‑reactive protein and interleukin‑6 in the evaluation of traumatic shock

Yang Li, Ling Chen, Wenge Fang, Huihong Chen
Pages: 4586-4592
Published online on: 16 April 2019

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Article Open Access

Expression of TGF-β1 and miR-99a in serum of patients with early spontaneous abortion and correlation with hormone levels during pregnancy

Juping Xie, Yali Cao
Pages: 4593-4597
Published online on: 10 April 2019

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Article Open Access

Effect of rehabilitation therapy and nursing intervention on postoperative recovery of patients with hypertensive intracerebral hemorrhage

Xiuhua Liu, Ping Zhang, Caihong Guo, Jing Xu, Ming Hu
Pages: 4598-4604
Published online on: 15 April 2019

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Article Open Access

Efficacy and safety of intrathecal meropenem and vancomycin in the treatment of postoperative intracranial infection in patients with severe traumatic brain injury

Qiang Zhang, Hongxing Chen, Chao Zhu, Fangzhou Chen, Suohui Sun, Nan Liang, Wei Zheng
Pages: 4605-4609
Published online on: 18 April 2019

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Article Open Access

Multi‑walled carbon nanotube‑based systems for improving the controlled release of insoluble drug dipyridamole

Wenquan Zhu, Haitao Huang, Yan Dong, Cuiyan Han, Xiaoyu Sui, Baiyu Jian
Pages: 4610-4616
Published online on: 19 April 2019

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Article Open Access

Identification of potential therapeutic target genes in mouse mesangial cells associated with diabetic nephropathy using bioinformatics analysis

Xin Mou, Di Yi Zhou, Ying Hui Liu, Kaiyuan Liu, Danyang Zhou
Pages: 4617-4627
Published online on: 23 April 2019

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Article

Sustained bile drainage decreases the organs injuries via inflammation‑associated factors modulation in a severe acute pancreatitis rat model

Fuhai Wang, Qingbin Wen, Sai Zhang, Zhen Fu, Feng Liu, Jing Cui, Ju Liu, Hu Tian
Pages: 4628-4634
Published online on: 11 April 2019

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Article

miR‑219‑3p regulates the occurrence of hepatic fibrosis by targeting Smad2

Weihua Yin, Wei Zhang, Yanfang Zhu, Huihui Ni, Li Gong, Maoying Fu
Pages: 4635-4642
Published online on: 11 April 2019

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Article

Pre‑treatment with a combination of Shenmai and Danshen injection protects cardiomyocytes against hypoxia/reoxygenation‑ and H2O2‑induced injury by inhibiting mitochondrial permeability transition pore opening

Lin Li, Zhengmei Sha, Yanyan Wang, Dongli Yang, Jinghao Li, Zhenzhen Duan, Hongbo Wang, Yuhong Li
Pages: 4643-4652
Published online on: 02 April 2019

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Article

Reduced environmental stimuli is associated with improved insulin‑like growth factor‑1 levels and physical growth in very low birth weight premature infants

Yue‑Feng Chen, Chun‑Wang Lin, Jin‑Feng Zhang, Min Lu, Yanfeng Li, Yanbin Yu
Pages: 4653-4656
Published online on: 16 April 2019

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Article

Expression of miRNA‑214 in the sera of elderly patients with acute myocardial infarction and its effect on cardiomyocyte apoptosis

Yugang Yin, Lei Lv, Wenni Wang
Pages: 4657-4662
Published online on: 03 April 2019

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Article

Combined effects of XAF1 and TRAIL on the apoptosis of lung adenocarcinoma cells

Fuquan Zhang, Donglai Chen, Wentao Yang, Shanzhou Duan, Yongbing Chen
Pages: 4663-4669
Published online on: 16 April 2019

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Article

MicroRNA‑146a regulates the transformation from liver fibrosis to cirrhosis in patients with hepatitis B via interleukin‑6

Zhaohui Yang, Yulong Peng, Suxian Yang
Pages: 4670-4676
Published online on: 16 April 2019

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Case Report

A floating inferior alveolar neurovascular bundle in a simple bone cyst: A case report

Shinpei Matsuda, Hitoshi Yoshimura, Kazuo Sano
Pages: 4677-4680
Published online on: 03 April 2019

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Article

Finite element analysis for blood accumulation in intracerebral hemorrhage

Peng Ren, Bo‑Chu Wang, Ya‑Zhou Wang, Hai‑Jian Xia, Ting‑Wang Guo, Xiao‑Fei Li
Pages: 4681-4686
Published online on: 10 April 2019

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Article

Protective effects of Asiatic acid against pelvic inflammatory disease in rats

Dejia Kong, Ping Fu, Qin Zhang, Xian Ma, Ping Jiang
Pages: 4687-4692
Published online on: 17 April 2019

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Article

MicroRNA‑153 inhibits cell proliferation, migration, invasion and epithelial‑mesenchymal transition in breast cancer via direct targeting of RUNX2

Zhongkun Zuo, Fei Ye, Ziru Liu, Jiangsheng Huang, Yi Gong
Pages: 4693-4702
Published online on: 05 April 2019

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Article

Long non‑coding RNA BLACAT1 promotes the proliferation and invasion of glioma cells via Wnt/β‑catenin signaling

Xiushan Li, Shujing Qi, Dongzhou Ma, Jinbiao Fan, Jingtao Wang
Pages: 4703-4708
Published online on: 05 April 2019

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Article

Role of gene promoter methylation regulated by TETs and DNMTs in the overexpression of HLA‑G in MCF‑7 cells

Daoyu Zhang, Xinglan An, Ziyi Li, Sheng Zhang
Pages: 4709-4714
Published online on: 11 April 2019

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Article

Long non‑coding RNA DLX6‑AS1 silencing inhibits malignant phenotypes of gastric cancer cells

Xiaodan Fu, Yifu Tian, Weilu Kuang, Sailan Wen, Wei Guo
Pages: 4715-4722
Published online on: 23 April 2019

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Article

Efficacy of intravenous lidocaine in improving post‑operative nausea, vomiting and early recovery after laparoscopic gynaecological surgery

Tao Wang, Hui Liu, Jian Hong Sun, Lin Wang, Jian You Zhang
Pages: 4723-4729
Published online on: 17 April 2019

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Article

Factors associated with disease progression and viral replication in patients with chronic hepatitis B virus infection

Jing Jia, Yonghong Li, Chaojun Wei, Rui Guo, Hui Xu, Yanjuan Jia, Yu Wu, Yuanting Li, Zhenhong Wei, Xiaoming Qi, Zhenhao Li, Xiaoling Gao
Pages: 4730-4740
Published online on: 11 April 2019

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Article

MicroRNA‑765 is pregulated in multiple myeloma and serves an oncogenic role by directly targeting SOX6

Shifeng Long, Shengping Long, Honglei He, Guoan Chen
Pages: 4741-4747
Published online on: 10 April 2019

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Article

Anti‑diarrheal effect of Scutellaria baicalensis is associated with suppression of smooth muscle in the rat colon

Hyun Ju Kim, Jun‑Ho La, Hee Man Kim, Il‑Suk Yang, Tae Sik Sung
Pages: 4748-4756
Published online on: 05 April 2019

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Journal Cover
April-2026 Volume 31 Issue 4

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Article Open Access

DKK1/SMDT1 participate in Ang II‑induced mitochondrial injury of human smooth muscle cells in an abdominal aortic aneurysm cell model

Xiaoxia Chang, Baohong Yao, Zheng Liu, Zijie Guo, Pengyue Qiao, Xiaokun Li, Lin Wang, Aiqun Li
Article Number: 117
Published online on: 25 February 2026

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[Retracted] Vascular endothelial growth factor participates in modulating the C6 glioma‑induced migration of rat bone marrow‑derived mesenchymal stem cells and upregulates their vascular cell adhesion molecule‑1 expression

Zhiqiang Gao, Peng Cheng, Yixue Xue, Yunhui Liu
Article Number: 116
Published online on: 24 February 2026

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Case Report Open Access

Rhabdomyolysis in a patient with lung cancer with sintilimab‑induced overlap syndrome and hypothyroidism: A case report

Bingyi Chen, Yi Liu, Qin Zeng, Shitong Yan, Xiujuan Liu, Quanlin Zhao
Article Number: 115
Published online on: 17 February 2026

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Secondary pulmonary lymphoma diagnosed by minimal residual disease detected in bronchoalveolar lavage fluid: A case report

Yingying Hu, Zheng Lv, Lehao Ren, Xin Zhao, Hong Liu, Yin Yuan
Article Number: 114
Published online on: 17 February 2026

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Gut microbiota‑metabolism axis in digestive tumors: Emerging targets for novel therapies (Review)

Zhendong Yang, Siyu Wu, Xueying Yang, Bowen Sui
Article Number: 113
Published online on: 17 February 2026

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[Retracted] Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis

Ying Xu, Guo-Jing Dai, Qian Liu, Zhen-Li Liu, Zhi-Qian Song, Li Li, Wei-Heng Chen, Na Lin
Article Number: 112
Published online on: 16 February 2026

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Metformin triggers apoptosis via endoplasmic reticulum stress in HER2‑positive breast cancer cell lines

Eser Çakmak, Bi̇rşen Bi̇lgi̇ci̇
Article Number: 111
Published online on: 13 February 2026

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Identification of a novel PLS1 heterozygous variant causing autosomal dominant non‑syndromic hearing loss

Chenxi Yang, Yao Xiong, Dongyang Wang, Juanzi Shi
Article Number: 110
Published online on: 12 February 2026

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Case Report

Familial SCA14: A case report with review

Han-Ke Huang, Chia-Ju Lee, Wen-Ling Cheng, Hui-Ju Chang, Chin-San Liu
Article Number: 109
Published online on: 12 February 2026

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Article Open Access

Efficacy of opioids in combination with gabapentin vs. opioids alone in the treatment of patients with cancer‑related pain due to bone metastases from malignant neoplasms: A meta‑analysis

Hongli Zhou, Jun Feng, Zuolei Tang
Article Number: 108
Published online on: 12 February 2026

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Article Open Access

Drug‑related problems in pediatric patients with chronic kidney disease: A single‑center prospective study

Xingxing Liu, Yue Li, Zhen Mao, Xin Wang, Shan Zhao, Qiu Han, Jia Liu, Yan Zhou, Shi Li, Bing Chen, Yongfu Hang, Wan Yan, Xiaoye Jin
Article Number: 107
Published online on: 12 February 2026

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Article Open Access

Effects of the WNT signaling pathway on inflammation and fibrosis in idiopathic pulmonary fibrosis: Clinical, radiological and molecular evaluation

İlknur Kaya, Ayşe Koçak Sezgi̇n, Meliha Koldemi̇r Gündüz, Şebnem Emine Parspur, Feride Marim, Mehmet Doğan, Ümran Toru Erbay
Article Number: 106
Published online on: 11 February 2026

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Article

IGFBP1 as a metabolic‑neurodegenerative biomarker in spinocerebellar ataxia type 3

Chungmin Chiu, Wenling Cheng, Tatsung Lin, Huiju Chang, Yujun Chang, Shihli Su, Chiaju Lee, Henhong Chang, Chinsan Liu
Article Number: 105
Published online on: 10 February 2026

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Case Report Open Access

Endodontic re‑treatment of the mandibular first molar with six root canals: A case report

Chen Wang, Mengyu Liu
Article Number: 104
Published online on: 09 February 2026

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Retraction Open Access

[Retracted] Effect of enhanced expression of COL8A1 on lymphatic metastasis of hepatocellular carcinoma in mice

Zhen-Hai Ma, Jin-Hui Ma, Li Jia, Yong-Fu Zhao
Article Number: 103
Published online on: 09 February 2026

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Article Open Access

Surgical treatment of extrahepatic intraabdominal hydatid cysts: A single‑centre retrospective analysis

Fatih Dal, Tutkun Talih, Muhammet Akyüz, Uğur Topal, Gökhan Sönmez, Erdoğan Mütevelli Sözüer, Hizir Yakup Akyildiz, Mustafa Karaağaç, Sedat Çarkit, Doğan Gürkan İslam
Article Number: 102
Published online on: 09 February 2026

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Article Open Access

Analysis of independent prognostic factors for the occurrence and severity of heart failure after chemotherapy in patients with small cell lung cancer 

Jieqiong Zhao, Xiao Wang, Xiaoxue Liu, Wei Zhao, Xia Lu, Ruijie Li, Xiang Sun
Article Number: 101
Published online on: 09 February 2026

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Case Report

Sagittal sinus thrombosis in pregnancy: A case report

Zaheera Saadia, Misbah Ilyas, Jayd Saud Althwiny, Fai Alaqel, Alanoud Abdullah Alsufayri, Lujain Husain Almutairi
Article Number: 100
Published online on: 05 February 2026

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Article

Elevated PGE2 and COX‑2 expression in villous adenoma: Implications for electrolyte depletion syndrome

Shiki Fujino, Hiroyuki Fukuda, Katsuki Danno, Takashi Takeda, Masaya Higashiguchi, Kozo Noguchi, Takefumi Hirao, Aya Ito, Norikatsu Miyoshi, Yoshio Oka
Article Number: 99
Published online on: 04 February 2026

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Article Open Access

Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation

Yu Lu, Xiaomei Zhou, Yiyu Guo, Fengrui Zhang, Jirong Wang, Jinhong Ge, Yan Xiao, Dengke Yang
Article Number: 98
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Glibenclamide exacerbates adriamycin‑induced cardiotoxicity by activating oxidative stress‑induced endoplasmic reticulum stress in rats

Meng-Lin Liu, Meng-Long Wang, Jing-Jun Lv, Jie Wei, Jun Wan
Article Number: 97
Published online on: 04 February 2026

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Review

Key role of the autonomic nervous system in breast cancer (Review)

Min Wu, Zhiwu Zhang, Lu Zhou, Shiqi Liu, Qing Chen, Cui Guo, Shasha Zhao, Xuedan Chen
Article Number: 96
Published online on: 04 February 2026

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Review Open Access

Senescent hepatic stellate cells drive inflammation and disease progression in MASH (Review)

Zhiqi Han, Yiran She, Di Wu, Nuo Zhang, Zheyuan Liu, Zhongyuan Wang, Xiaoying Zhou, Shuo Li
Article Number: 95
Published online on: 04 February 2026

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Article Open Access

PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

Zilong Zhang, Hangyu Zhou, Diliyaer Adili, Wei Zhu, Yong Liu, Wenzheng Zhou, Zhao Wang, Jie Li
Article Number: 94
Published online on: 04 February 2026

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Case Report

A novel human papillomavirus‑induced ‘doughnut wart’ lesion treated with 5‑aminolevulinic acid photodynamic therapy: A case report

Ke Li, Yitao Qian, Wenjing Zha, Lei Shi
Article Number: 93
Published online on: 04 February 2026

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Case Report Open Access

Comprehensive diagnosis and individualized treatment of multiple primary lung cancer: A case report

Guoxiong Zeng, Yunyan Zhou, Wang Wan, Biao Deng, Chunyuan Chen, Zhu Liang
Article Number: 92
Published online on: 03 February 2026

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Review Open Access

Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review)

Hong Zhou, Wenwen Yu, Jiaming Lei, Runzhi Chang, Yingjia Cheng, Guorui Wang, Li Lin
Article Number: 91
Published online on: 03 February 2026

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Case Report Open Access

A rare upstream regulatory region mutation in APC presenting as classical familial adenomatous polyposis: A case report and literature review

Chi-Han Yang, Yen-Cheng Chen, Tsung-Kun Chang, Wei-Chih Su, Ching-Wen Huang, Hsiang-Lin Tsai, Jaw-Yuan Wang
Article Number: 90
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] lncRNA MIAT promote cell invasion and migration in esophageal cancer

Weiguo Zhang, Qiang Chen, Caipeng Lei
Article Number: 89
Published online on: 02 February 2026

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Review Open Access

Mitochondria‑driven ferroptosis in intervertebral disc degeneration: A novel target in age‑related spinal diseases (Review)

Yang Hou, Xiaolei Yang, Duorun Qiu, Lei Liu, Jiangang Shi, Yongfei Guo
Article Number: 88
Published online on: 02 February 2026

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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

Jingxian Li, Fang Wang, Yuanshu Du, Yonghui Wang
Article Number: 87
Published online on: 02 February 2026

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Case Report Open Access

Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report

Bin He, Lin Ling Li, Ting Yu, Yu Tan, Ling Zhang
Article Number: 86
Published online on: 29 January 2026

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Article Open Access

Myrrh ameliorates endometriosis by enhancing ER stress‑related apoptotic cell death

Bo-Sung Kim, Minkyoung Cho, Jung Ho Han, Jung-Sook Jin, Sung-Jin Bae, Yunju Jo, Dongryeol Ryu, Yerim Joo, Seon Beom Kim, Jongkil Joo, Inhye Kim, Ki-Tae Ha
Article Number: 85
Published online on: 29 January 2026

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May-2026 Volume 31 Issue 5

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Article

Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
Published online on: 09 March 2026

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Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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Retraction Open Access

[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
Published online on: 09 March 2026

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Case Report Open Access

Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
Published online on: 06 March 2026

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Case Report

Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report

Yajun Yao, Ge-Hong Dong, De-Cai Tian
Article Number: 129
Published online on: 06 March 2026

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Article

Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta‑analysis

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 128
Published online on: 06 March 2026

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Article

Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Case Report

Management after two consecutive suction losses during small‑incision lenticule extraction: A case report

Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
Published online on: 03 March 2026

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Case Report Open Access

Hematemesis resulting from mesenteric venous thrombosis: A case report

Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
Article Number: 125
Published online on: 02 March 2026

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Article

Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Article

Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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Article Open Access

RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
Published online on: 27 February 2026

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Case Report

A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Review Open Access

Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review)

Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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