Open Access

A case‑control study of the relationship between visceral fat and development of uterine fibroids

  • Authors:
    • Kejuan Sun
    • Ying Xie
    • Na Zhao
    • Zengning Li
  • View Affiliations

  • Published online on: May 10, 2019     https://doi.org/10.3892/etm.2019.7575
  • Pages: 404-410
  • Copyright: © Sun et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Relationship between visceral fat and development of uterine fibroids in adult women was investigated. A total of 89 patients with uterine fibroids treated in the First Hospital of Hebei Medical University from April 2016 to April 2018 were enrolled. Another 81 healthy women without uterine fibroids receiving physical examination in the same period were selected as the control group. Self‑designed questionnaires were used to investigate the general conditions of the subjects, bioelectrical impedance analysis was employed to analyze obesity‑related indicators, and their correlation with the risk of uterine fibroids was explored. Visceral fat area (VFA), body mass index (BMI), body fat percentage, waist circumference, waist‑height ratio and waist‑hip ratio were positively correlated with the incidence rate of uterine fibroids, and the odds ratio (OR), 95% confidence interval (CI) was 3.910 (2.029, 7.536), 2.716 (1.444, 5.110), 4.335 (1.507, 12.469), 2.881 (1.531, 5.423), 3.837 (1.914, 7.692) and 7.707 (3.501, 16.965), respectively. VFA and body fat percentage were correlated with the size of uterine fibroids, but the correlations were relatively weak. With the increase in the VFA, BMI, waist circumference, waist‑height ratio, and waist‑hip ratio, the risk of uterine fibroids was elevated. The BMI, VFA and waist circumference of patients with uterine fibroids were gradually increased with increasing age, showing statistically significant differences. Increased body fat (especially abdominal visceral fat) is able to enhance the risk of uterine fibroids. For perimenopausal women, the waist‑hip ratio measured can be used as an indicator screening high‑risk groups of uterine fibroids. This method is simple, easy and inexpensive. At the same time, providing nutrition guidance and changing diet and exercise habits are important measures to prevent the development of uterine fibroids.
View References

Related Articles

Journal Cover

July-2019
Volume 18 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Sun K, Xie Y, Zhao N and Li Z: A case‑control study of the relationship between visceral fat and development of uterine fibroids. Exp Ther Med 18: 404-410, 2019
APA
Sun, K., Xie, Y., Zhao, N., & Li, Z. (2019). A case‑control study of the relationship between visceral fat and development of uterine fibroids. Experimental and Therapeutic Medicine, 18, 404-410. https://doi.org/10.3892/etm.2019.7575
MLA
Sun, K., Xie, Y., Zhao, N., Li, Z."A case‑control study of the relationship between visceral fat and development of uterine fibroids". Experimental and Therapeutic Medicine 18.1 (2019): 404-410.
Chicago
Sun, K., Xie, Y., Zhao, N., Li, Z."A case‑control study of the relationship between visceral fat and development of uterine fibroids". Experimental and Therapeutic Medicine 18, no. 1 (2019): 404-410. https://doi.org/10.3892/etm.2019.7575