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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2019 Volume 18 Issue 1

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Impact Factor: 2.2

Article Open Access

Cytotoxic and apoptotic effects of different extracts of Moringa oleifera Lam on lymphoid and monocytoid cells

Marina Potestà, Antonella Minutolo, Angelo Gismondi, Lorena Canuti, Maurice Kenzo, Valentina Roglia, Federico Macchi, Sandro Grelli, Antonella Canini, Vittorio Colizzi, Carla Montesano
Pages: 5-17
Published online on: 03 May 2019

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Article

Interventional magnetic resonance imaging as a diagnostic and therapeutic method in treating acute pediatric atlantoaxial rotatory subluxation

Juuli Hannonen, Marja Perhomaa, Niina Salokorpi, Willy Serlo, Roberto Blanco Sequeiros, Jaakko Sinikumpu
Pages: 18-24
Published online on: 09 May 2019

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Article

Long non‑coding RNA UCA1 promotes proliferation and invasion of intrahepatic cholangiocarcinoma cells through targeting microRNA‑122

Ou Li, Weimin Yi, Pingzhou Yang, Chao Guo, Chuang Peng
Pages: 25-32
Published online on: 09 May 2019

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Article Open Access

Scutellarin‑treated exosomes increase claudin 5, occludin and ZO1 expression in rat brain microvascular endothelial cells

Xiaoqin Zhong, Chuanjin Luo, Minzhen Deng, Min Zhao
Pages: 33-40
Published online on: 08 May 2019

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Article Open Access

Fluorofenidone affects hepatic stellate cell activation in hepatic fibrosis by targeting the TGF‑β1/Smad and MAPK signaling pathways

Yu Peng, Li Li, Xin Zhang, Mingyan Xie, Congying Yang, Sha Tu, Hong Shen, Gaoyun Hu, Lijian Tao, Huixiang Yang
Pages: 41-48
Published online on: 06 May 2019

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Article Open Access

Correlation between carotid intima‑media roughness and cardiovascular risk factors

Yu Wu, Xuan Lu, Li Zhang, Xinyao Cheng, Li Yuan, Mingxing Xie, Qing Lv
Pages: 49-56
Published online on: 04 June 2019

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Article

Application of transforaminal‑lumbar interbody fusion technology combined with lesion clearance and chemotherapy via catheter for the treatment of spinal tuberculosis

Yibin Meng, Yunfei Hang, Dingjun Hao, Shuaijun Jia, Xirui He, Deyin Liu, Liang Sun
Pages: 57-62
Published online on: 30 April 2019

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Article Open Access

Clinical efficacy of gangliosides on premature infants suffering from white matter damage and its effect on the levels of IL‑6, NSE and S100β

Xiaopeng Wang, Xiuying Tian, Junling Ma, Jun Zheng
Pages: 63-68
Published online on: 02 May 2019

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Article Open Access

Effects of etanercept, a tumor necrosis factor receptor fusion protein, on primary cell cultures prepared from intact human intervertebral disc tissue

Tezcan Caliskan, Duygu Yasar Sirin, Numan Karaarslan, Ibrahim Yilmaz, Hanefi Ozbek, Yener Akyuva, Necati Kaplan, Yasin Emre Kaya, Abdullah Talha Simsek, Aliye Yildirim Guzelant, Ozkan Ates
Pages: 69-76
Published online on: 08 May 2019

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Article Open Access

MicroRNA‑15b participates in the development of peripheral arterial disease by modulating the growth of vascular smooth muscle cells

Yong Sun, Yong Gao, Tao Song, Chaowen Yu, Zhonglin Nie , Xiaogao Wang
Pages: 77-84
Published online on: 07 May 2019

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Article Open Access

Adenosine antagonists for prevention of contrast‑induced nephropathy: A meta‑analysis of randomized controlled trials with trial sequential analysis

Hongbin Zang, Qiongyu Zhang, Xiaodong Li
Pages: 85-98
Published online on: 09 May 2019

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Article Open Access

Allogeneic adipose-derived stem cell transplantation on knee osteoarthritis rats and its effect on MMP-13 and DDR2

Jianrui Li, Xiaobo Zhu, Qin Shao, Feini Xu, Guixin Sun
Pages: 99-104
Published online on: 08 May 2019

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Article Open Access

Influence of neonatal gender on cord blood CD34+ cell amplification and gene expression

Liping Zhou, Zhe Che, Xiaowei Zhang, Panpan Zhou, Xue Li, Xuejing Xu, Qing Shi, Dong Li, Xiuli Ju
Pages: 105-118
Published online on: 07 May 2019

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Article Open Access

LINK‑A lncRNA activates HIF1α signaling and inhibits podocyte cell apoptosis in diabetic nephropathy

Jing Yang, Lihua Li, Shijun Hong, Zhu Zhou, Wenxing Fan
Pages: 119-124
Published online on: 03 May 2019

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Article

Altered spontaneous brain activity patterns in patients with corneal ulcer using amplitude of low‑frequency fluctuation: An fMRI study

Wen‑Qing Shi, Wei Wu, Lei Ye, Nan Jiang, Wen‑Feng Liu, Yong‑Qiang Shu, Ting Su, Qi Lin, You‑Lan Min, Biao Li, Pei‑Wen Zhu, Yi Shao
Pages: 125-132
Published online on: 07 May 2019

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Article

Puerarin alleviates liver fibrosis via inhibition of the ERK1/2 signaling pathway in thioacetamide‑induced hepatic fibrosis in rats

Xiuqing Li, Hui Zhang, Lijuan Pan, Haiou Zou, Xiaonan Miao, Jing Cheng, Youshan Wu
Pages: 133-138
Published online on: 30 April 2019

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Article

miRNA‑344b‑1‑3p modulates the autophagy of NR8383 cells during Aspergillus fumigatus infection via TLR2

Yuting Wu, Hong Xu, Yongqiang Li, Dongwei Huang, Lu Chen, Yahui Hu, Li Li, Deming Zhang, Wenjie Huang
Pages: 139-146
Published online on: 10 May 2019

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Article

Isolation of high γ‑aminobutyric acid‑producing lactic acid bacteria and fermentation in mulberry leaf powders

Yangsheng Zhong, Shan Wu, Fangyan Chen, Mengxiu He, Jianrong Lin
Pages: 147-153
Published online on: 08 May 2019

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Article

Comparison of the detection of colorectal lesions in different endoscopic modalities: A network meta‑analysis and systematic review

Lifu Li, Yinghua Ou, Hui Yue, Hong Sun, Peisheng Chen, Suying Liu, Fengjian He, Qianqian Peng, Sanhua Deng
Pages: 154-162
Published online on: 30 April 2019

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Article Open Access

Angiogenesis and bone regeneration by mesenchymal stem cell transplantation with danshen in a rabbit model of avascular necrotic femoral head

Yungang Wu, Chunwu Zhang, Jianjing Wu, Yan Han, Chunlei Wu
Pages: 163-171
Published online on: 08 May 2019

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Article Open Access

Optimal ratio of 18α‑ and 18β‑glycyrrhizic acid for preventing alcoholic hepatitis in rats

Xiaowei Huo, Xiaoke Sun, Zepeng Cao, Jingzhe Qiao, Sa Yang, Xiangbo Meng, Yanyan Zhao
Pages: 172-178
Published online on: 10 May 2019

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Article Open Access

Plasma‑derived exosomal miR‑183 associates with protein kinase activity and may serve as a novel predictive biomarker of myocardial ischemic injury

Xingxing Zhao, Yongping Jia, Huanzhen Chen, Hongmei Yao, Wenlin Guo
Pages: 179-187
Published online on: 08 May 2019

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Article Open Access

Targeted metabolomics for serum amino acids and acylcarnitines in patients with lung cancer

Junjun Ni, Li Xu, Wei Li, Chunmei Zheng, Lijun Wu
Pages: 188-198
Published online on: 30 April 2019

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Article Open Access

Oncogenic role of long non‑coding RNA SNHG12 in gastric cancer cells by targeting miR‑16

Guodong Zhao, Suineng Wang, Xianwen Liang, Chunfang Wang, Bo Peng
Pages: 199-208
Published online on: 24 April 2019

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Article Open Access

MicroRNA‑30a suppresses papillary thyroid cancer cell proliferation, migration and invasion by directly targeting E2F7

Haiyan Guo, Linyun Zhang
Pages: 209-215
Published online on: 30 April 2019

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Article Open Access

Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue

Feride Sinem Akgun, Duygu Yasar Sirin, Ibrahim Yilmaz, Numan Karaarslan, Hanefi Ozbek, Abdullah Talha Simsek, Yasin Emre Kaya, Necati Kaplan, Yener Akyuva, Tezcan Caliskan, Ozkan Ates
Pages: 216-224
Published online on: 13 May 2019

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Article Open Access

Expression of BMP‑4 and Smad1 in patients with Hirschsprung disease and its clinical significance

Jianjun Zhang, Fengli Liu
Pages: 225-229
Published online on: 25 April 2019

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Article

Lazaroid U‑74389G in liver ischemia‑reperfusion injury: A swine model

Maria I. Korontzi, George Theodoropoulos, George Agrogiannis, Ioannis Flessas, Dimosthenis Chrysikos, Aristea Gioxari, Theodoros N. Sergentanis, Efstratios Patsouris, George C. Zografos, Apostolos Papalois
Pages: 230-236
Published online on: 08 May 2019

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Article Open Access

Toxicity mechanism of sevoflurane in neural stem cells of rats through DNA methylation

Ka Wang, Yi Tian, Yingai Zhang, Xuying Li, Xiao Wei, Haiyou Hu, Shiyuan Xu
Pages: 237-241
Published online on: 08 May 2019

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Article Open Access

Ex vivo construction of rabbit corneal endothelial cell sheets on a porcine descemet membrane graft

Chunyu Liu, Shenfei Tang, Guozhen Niu, Juan Zhang, Xinyu Huang, Yushan Zhang, Yanlong Bi
Pages: 242-252
Published online on: 10 May 2019

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Article

Downregulation of microRNA‑204 increases the expression of matrix metallopeptidase 9 in pediatric patients with pulpitis and Helicobacter pylori infection in the stomach

Shu Zhou, Ji Xu
Pages: 253-259
Published online on: 25 April 2019

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Article

Efficacy of long‑term treatment with tenofovir in Chinese nucleos(t)ide‑naïve chronic hepatitis B patients regardless of baseline viral load

Jie Luo, Xu You, Yutian Chong, Yuankai Wu, Jiao Gong, Yusheng Jie, Xinhua Li, Sujuan Xi, Zhiwei Zhang, Yufeng Zhang, Dongying Xie, Zhanyi Li, Xiangyong Li
Pages: 260-268
Published online on: 06 May 2019

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Article Open Access

LRRFIP1 expression triggers platelet agglutination by enhancing αIIbβ3 expression

Xiang Yin, Peng Liu, Yao‑Yao Liu, Ming‑Yong Liu, Wei‑Li Fan, Bai‑Yi Liu, Jian‑Hua Zhao
Pages: 269-277
Published online on: 10 May 2019

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Article Open Access

Identification of differentially expressed genes, associated functional terms pathways, and candidate diagnostic biomarkers in inflammatory bowel diseases by bioinformatics analysis

Chunwei Cheng, Juan Hua, Jun Tan, Wei Qian, Lei Zhang, Xiaohua Hou
Pages: 278-288
Published online on: 03 May 2019

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Article Open Access

Comparison of ultrasound‑guided iliohypogastric/ilioinguinal nerve block and transversus abdominis plane block for analgesia after cesarean section: A retrospective propensity match study

Yulu Jin, Yongliang Li, Sanrong Zhu, Guangfeng Zhu, Min Yu
Pages: 289-295
Published online on: 03 May 2019

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Article Open Access

miR‑206 regulates alveolar type II epithelial cell Cx43 expression in sepsis‑induced acute lung injury

Jiawei Zhou, Yumei Fu, Kai Liu, Linyi Hou, Wenkai Zhang
Pages: 296-304
Published online on: 07 May 2019

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Article

Early short‑term ivabradine treatment in new‑onset acute systolic heart failure and sinus tachycardia patients with inflammatory rheumatic disease

Wei Wu, Lixi Zhang, Jiuliang Zhao, Yuchao Guo, Jinjing Liu, Di Shi, Jing Yang, Yingxian Liu, Jinzhi Lai, Zhujun Shen
Pages: 305-311
Published online on: 25 April 2019

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Article

miR‑877‑3p promotes TGF‑β1‑induced osteoblast differentiation of MC3T3‑E1 cells by targeting Smad7

Guisong He, Jianming Chen, Dong Huang
Pages: 312-319
Published online on: 10 May 2019

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Article Open Access

Effect of oral mucosal transplantation on the expression of EGF and VEGF‑C during skin wound repair

Shumei Qi, Changxi Yang, Mingzhen Zhu, Hui Chen
Pages: 320-325
Published online on: 06 May 2019

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Article Open Access

Evaluation of fibroblast growth factor‑2 on the proliferation of osteogenic potential and protein expression of stem cell spheroids composed of stem cells derived from bone marrow

Jae‑Yong Tae, Youngkyung Ko, Jun‑Beom Park
Pages: 326-331
Published online on: 03 May 2019

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Article

Enterovirus type 71‑immunized chicken egg yolk immunoglobulin has cross antiviral activity against coxsackievirus A16 in vitro

Enyi Gao, Shuwen Wu, Qing Xu, Yonglian Zeng, Ning Tan, Songqing He, Yang Yang, Jingchen Wei
Pages: 332-341
Published online on: 25 April 2019

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Article Open Access

Meta‑analysis of the efficacy of liraglutide in patients with type 2 diabetes accompanied by incipient nephropathy

Wei Liu, Jiangyi Yu, Ting Tian, Junjun Miao, Wenbin Shang
Pages: 342-351
Published online on: 13 May 2019

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Article Open Access

Transvaginal/transrectal ultrasound-guided aspiration biopsy for diagnosis of pelvic/pelvic floor tumors in females: A retrospective analysis

Chuanfen Gao, Ling Wang, Chaoxue Zhang, Xin Li
Pages: 352-357
Published online on: 09 May 2019

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Article Open Access

Platelet‑rich fibrin increases the osteoprotegerin/receptor activator of nuclear factor‑κB ligand ratio in osteoblasts

Ryuta Sumida, Toyonobu Maeda, Ichiro Kawahara, Junko Yusa, Yasumasa Kato
Pages: 358-365
Published online on: 08 May 2019

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Article Open Access

Management of unilateral staghorn renal stones with concurrent urinary tract infections by retroperitoneal laparoscopic pyelolithotomy with prolonged renal posterior lower segment incision

Bowen Shi, Xi Hong, Jianjun Yu
Pages: 366-372
Published online on: 03 May 2019

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Article Open Access

RNA‑seq analysis of blood of valproic acid‑responsive and non‑responsive pediatric patients with epilepsy

Yan Wang, Zhiping Li
Pages: 373-383
Published online on: 30 April 2019

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Article Open Access

Fetal microtia and FGFR2 polymorphism

Ruilian Zhao, Peixia Du, Hongmei Sun, Li Yang, Pingzhen Lin
Pages: 384-388
Published online on: 10 May 2019

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Article Open Access

MicroRNA‑18 promotes apoptosis of islet β‑cells via targeting NAV1

Honghua Fei, Mingyan Shi, Lianhong Chen, Zhe Wang, Lihua Suo
Pages: 389-396
Published online on: 24 April 2019

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Article

Insulin therapy is not associated with improved clinical outcomes in critically ill infants with stress hyperglycemia

Fang Wen, Yi Zhang, Chunwang Lin, Minghong Deng, Jinfeng Zhang, Jianping Zhang
Pages: 397-403
Published online on: 30 April 2019

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Article Open Access

A case‑control study of the relationship between visceral fat and development of uterine fibroids

Kejuan Sun, Ying Xie, Na Zhao, Zengning Li
Pages: 404-410
Published online on: 10 May 2019

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Article Open Access

Clinical efficacy of montelukast sodium combined with budesonide or combined with loratadine in treating children with cough variant asthma and influence on inflammatory factors in the serum

Haiyan Wei, Weihua Li, Zhen Jiang, Xiaoying Xi, Gongjian Qi
Pages: 411-417
Published online on: 10 May 2019

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Article Open Access

Downregulation of miR‑152 contributes to the progression of liver fibrosis via targeting Gli3 in vivo and in vitro

Li Li, Lei Zhang, Xiongqi Zhao, Jun Cao, Jingfeng Li, Guang Chu
Pages: 425-434
Published online on: 20 May 2019

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Article Open Access

Knockdown of lncRNA‑HOTAIR downregulates the drug‑resistance of breast cancer cells to doxorubicin via the PI3K/AKT/mTOR signaling pathway

Zhixiang Li, Jun Qian, Jing Li, Chao Zhu
Pages: 435-442
Published online on: 29 May 2019

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Article Open Access

Activation of multiple Toll‑like receptors serves different roles in sepsis‑induced acute lung injury

Xinlei Chen, Tingting Wang, Liang Song, Xiangyan Liu
Pages: 443-450
Published online on: 23 May 2019

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Article Open Access

Identification of key candidate genes for pancreatic cancer by bioinformatics analysis

Kui Lv, Jianying Yang, Junfeng Sun, Jianguo Guan
Pages: 451-458
Published online on: 28 May 2019

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Article Open Access

Resveratrol protects against asthma‑induced airway inflammation and remodeling by inhibiting the HMGB1/TLR4/NF‑κB pathway

Huanhuan Jiang, Junyan Duan, Kaihong Xu, Wenbo Zhang
Pages: 459-466
Published online on: 20 May 2019

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Article Open Access

Edaravone attenuates traumatic brain injury through anti‑inflammatory and anti‑oxidative modulation

Man Zhang, Chen‑Huai Teng, Fang‑Fang Wu, Li‑Yun Ge, Jian Xiao, Hong‑Yu Zhang, Da‑Qing Chen
Pages: 467-474
Published online on: 30 May 2019

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Article Open Access

Downregulation of miR‑485‑3p promotes glioblastoma cell proliferation and migration via targeting RNF135

Ye Zhang, Rui Sui, Yi Chen, Haiyang Liang, Ji Shi, Haozhe Piao
Pages: 475-482
Published online on: 23 May 2019

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Article Open Access

Expression levels and significance of miR-184 and miR-126 in burned rats

Sida Xu, Youfen Fan, Tianbin Wu, Pei Xu
Pages: 483-488
Published online on: 13 May 2019

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Article Open Access

Reduced miR‑202 levels enhanced oral cancer development via targeting Sp1 Retraction in /10.3892/etm.2024.12539

Jia Zhao, Deguang Ding, Ge Zhao
Pages: 489-496
Published online on: 23 May 2019

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Article Open Access

RBP and Alb in neonatal hydronephrosis and its association with IL-12 levels in pregnant women before delivery

Zhi Ma, Dezhi Lu, Wanxin Zhao, Huizhi Wang
Pages: 497-502
Published online on: 23 May 2019

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Article Open Access

Effect of miR‑19b on the protective effect of Exendin‑4 on islet cells in non‑obese diabetic mice

Jinshui He, Yueya Kang, Chaowei Lian, Jinzhi Wu, Huowang Zhou, Xiaoling Ye
Pages: 503-508
Published online on: 22 May 2019

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Article Open Access

Lycium barbarum polysaccharide attenuates cardiac hypertrophy, inhibits calpain‑1 expression and inhibits NF‑κB activation in streptozotocin‑induced diabetic rats

Qianqian Liu, Qianqian Han, Meili Lu, Hongxin Wang, Futian Tang
Pages: 509-516
Published online on: 24 May 2019

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Article Open Access

Analysis of interleukin‑17 and interleukin‑18 levels in animal models of atherosclerosis

Xiuming Tang
Pages: 517-522
Published online on: 30 May 2019

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Article Open Access

Clinical characteristics and cerebro-spinal fluid cytokine changes in patients with acquired immunodeficiency syndrome and central nervous system infection

Zhong Chen, Ning Wang, Yaxiong Huang, Min Wang
Pages: 523-530
Published online on: 16 May 2019

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Article Open Access

Laryngoscope‑assisted and cotton ball wiping methods in prevention of oral and pulmonary infection in patients receiving mechanical ventilation and the influence on hypersensitive C‑reactive protein and procalcitonin

Pingji Zhang, Guoguang Xia, Li Dai, Yang Cheng, Zhuo Wang
Pages: 531-536
Published online on: 24 May 2019

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Efficacy of nickel‑titanium memory alloy in the treatment of multiple rib fracture combined with sternal fracture

Ming Xiong, Wei Hu, Qiang Lou, Shi Yin, Xin Wang
Pages: 537-542
Published online on: 22 May 2019

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Puerarin suppresses cell growth and migration in HPV‑positive cervical cancer cells by inhibiting the PI3K/mTOR signaling pathway

Lihua Jia, Yuling Hu, Guohua Yang, Peiling Li
Pages: 543-549
Published online on: 17 May 2019

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Overexpression of microRNA‑620 facilitates the resistance of triple negative breast cancer cells to gemcitabine treatment by targeting DCTD

Chao Wu, Aili Zhao, Tingzhao Tan, Yuan Wang, Zhentao Shen
Pages: 550-558
Published online on: 23 May 2019

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Effect of resveratrol on non‑alcoholic fatty liver disease

Marios Theodotou, Konstantinos Fokianos, Demetris Moniatis, Rudolf Kadlenic, Asimina Chrysikou, Andrea Aristotelous, Alexia Mouzouridou, John Diakides, Eliza Stavrou
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Published online on: 23 May 2019

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Effects of enhanced environment and induced depression on cuprizone mouse model of demyelination

Ayman Mohamed, Ghada Al-Kafaji, Amal Almahroos, Zahra Almosawi, Hawra Alalwan, Reem Abdulla, Fajer Alammadi, Ahmed Almubarak, Ahmed Al-Mahrezi, Amer Kamal
Pages: 566-572
Published online on: 10 June 2019

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Hydatid cyst of the thyroid gland with tracheal fistula: A case report and review of the literature

Tiemin Jiang, Qiang Guo, Bo Ran, Ruiqing Zhang, Tuerganaili Aji, Yingmei Shao
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Published online on: 28 May 2019

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Investigation of the underling mechanism of ketamine for antidepressant effects in treatment‑refractory affective disorders via molecular profile analysis

Jun Qiao, Yuan Sun, Jinfang Wu, Li Wang
Pages: 580-588
Published online on: 30 May 2019

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Outcomes of 23G vitrectomy and internal limiting membrane peeling with brilliant blue in patients with myopic foveoschisis from a retrospective cohort study

Xinbang Mao, Zhipeng You, Yanhua Cheng
Pages: 589-595
Published online on: 24 May 2019

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Eltrombopag enables initiation and completion of pegylated interferon/ribavirin therapy in Japanese HCV‑infected patients with chronic liver disease and thrombocytopenia

Takumi Kawaguchi, Atsumasa Komori, Kunio Fujisaki, Shuhei Nishiguchi, Michio Kato, Hitoshi Takagi, Yasuhito Tanaka, Kazuo Notsumata, Eiji Mita, Hideyuki Nomura, Mitsushige Shibatoge, Koichi Takaguchi, Toshihiro Hattori, Michio Sata, Kazuhiko Koike
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Published online on: 24 May 2019

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ΜicroRNA‑155 induces protection against cerebral ischemia/reperfusion injury through regulation of the Notch pathway in vivo

Tianpeng Jiang, Shi Zhou, Xing Li, Jie Song, Tianzhi An, Xueqin Huang, Xiuqin Ping, Lizhou Wang
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Published online on: 17 May 2019

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Soluble Tei2 fusion protein inhibits retinopathy of prematurity occurrence via regulation of the Ang/Tie2 pathway

Weijing Li, Weihua Zhang, Cuiying Zhang, Chunfang Zhu, Xiangling Yi, Yan Zhou, Yan Lv
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Published online on: 24 May 2019

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High glucose induces apoptosis of HUVECs in a mitochondria‑dependent manner by suppressing hexokinase 2 expression

Jia Zhang, Yanyan Guo, Wanyu Ge, Xia Zhou, Minglin Pan
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Published online on: 24 May 2019

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Reversal effect of ginsenoside Rh2 on oxaliplatin‑resistant colon cancer cells and its mechanism

Jun Ma, Guangyi Gao, Hong Lu, Dong Fang, Lingchang Li, Guoli Wei, Aifei Chen, Yong Yang, Hongying Zhang, Jiege Huo
Pages: 630-636
Published online on: 23 May 2019

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MMP-9 and TIMP-1 in placenta of hypertensive disorder complicating pregnancy

Yuyi Zhang, Peng Li, Yue Guo, Xiaowan Liu, Yubo Zhang
Pages: 637-641
Published online on: 17 May 2019

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Therapeutic effect of vitamin K1 combined with meropenem on the treatment of pertussis syndrome

Wenxin Chen, Yufeng Guo
Pages: 642-646
Published online on: 16 May 2019

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Regulatory effect of miR‑144‑3p on the function of human trabecular meshwork cells and fibronectin‑1

Ruoxi Yin, Xiaoya Chen
Pages: 647-653
Published online on: 15 May 2019

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Efficacy of pulmonary surfactant combined with high-dose ambroxol hydrochloride in the treatment of neonatal respiratory distress syndrome

Jiajun Xiang, Ping Wang
Pages: 654-658
Published online on: 24 May 2019

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Curative effect and prognosis of 3D printing titanium alloy trabecular cup and pad in revision of acetabular defect of hip joint

Lei Wan, Guangliang Wu, Pengke Cao, Kui Li, Junming Li, Shaoan Zhang
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Published online on: 28 May 2019

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miR‑490‑3p functions as a tumor suppressor in glioma by inhibiting high‑mobility group AT‑hook 2 expression

Fang Zhang, Anhao Wu, Yinhui Wang, Jianmin Liu
Pages: 664-670
Published online on: 23 May 2019

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Correlation between serum transforming growth factor β1, interleukin‑6 and neonatal respiratory distress syndrome

Feng Chen, Fang Huang, Fei Zhan
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Published online on: 15 May 2019

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Effect of HDAC2/Inpp5f on neuropathic pain and cognitive function through regulating PI3K/Akt/GSK‑3β signal pathway in rats with neuropathic pain

Lili Yuan, Caihua Liu, Yingchun Wan, Hong Yan, Tao Li
Pages: 678-684
Published online on: 28 May 2019

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Advanced glycation end products and adipocytokines and oxidative stress in placental tissues of pregnant women with gestational diabetes mellitus

Hongxia Li, Aihong Dong, Xiaoxia Lv
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Published online on: 28 May 2019

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lncRNA NEF inhibits glioma by downregulating TGF‑β1

Qiao Huang, Hua Chen, Bin Zuo, Chen Cheng, Wei Yu, Yuenan Yang
Pages: 692-698
Published online on: 23 May 2019

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Silencing PDK1 limits hypoxia‑induced pulmonary arterial hypertension in mice via the Akt/p70S6K signaling pathway

Ruomin Di, Zhongzhou Yang, Peng Xu, Yingjia Xu
Pages: 699-704
Published online on: 29 May 2019

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Calcified decellularized arterial scaffolds impact vascular smooth muscle cell transformation via downregulating α‑SMA expression and upregulating OPN expression

Huaping Xin, Zhimin Wang, Shuwu Wu, Peng Wang, Xiaoxiao Tao, Chenhua Xu, Liling You
Pages: 705-710
Published online on: 29 May 2019

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High accuracy of quantitative fluorescence polymerase chain reaction combined with non‑invasive pre‑natal testing for mid‑pregnancy diagnosis of common fetal aneuploidies: A single‑center experience in China

Ping Huo, Qiuyan Luo, Juan Li, Baoquan Jiao, Limin Rong, Jie Zhang, Xiaohua Wu
Pages: 711-721
Published online on: 29 May 2019

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Predictive value of procalcitonin for infection of patients with type‑2 diabetes mellitus

Xinshui Wang, Yanbei Sun, Xiaonan Shao
Pages: 722-728
Published online on: 24 May 2019

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Tanshinone IIA ameliorates diabetic cardiomyopathy by inhibiting Grp78 and CHOP expression in STZ‑induced diabetes rats

Shuliang Tao, Liuyin Chen, Jingmei Song, Ningning Zhu, Xueyi Song, Ruoli Shi, Gangfeng Ge, Yueming Zhang
Pages: 729-734
Published online on: 15 May 2019

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Brucine inhibits TNF‑α‑induced HFLS‑RA cell proliferation by activating the JNK signaling pathway

Min Tang, Wei‑Ji Zhu, Zu‑Cheng Yang, Cheng‑Song He
Pages: 735-740
Published online on: 15 May 2019

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Differential clinical benefits of continuous blood purification treatment in critically ill patients with variable APACHE II scores

Rui‑Xiang Zhou, Wei Dai, Chao‑Liang Hu
Pages: 741-746
Published online on: 28 May 2019

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Long‑term prognostic value of coronary computed tomography angiography for asymptomatic patients with CAD in type 2 diabetes mellitus

Peigang Tian, Xiangyang Zheng, Mingzhi Li, Weiwei Li, Qingliang Niu
Pages: 747-754
Published online on: 20 May 2019

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Article

AQP8 and AQP9 expression in patients with polycystic ovary syndrome and its association with in vitro fertilization‑embryo transfer outcomes

Zhengfang Xiong, Bing Li, Liyun Wang, Xianghui Zeng, Binye Li, Xiaoyan Sha, Huishu Liu
Pages: 755-760
Published online on: 20 May 2019

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Inhibition of TLR4 inhibits allergic responses in murine allergic rhinitis by regulating the NF‑κB pathway

Hangyu Xu, Hairong Shu, Jie Zhu, Jianxin Song
Pages: 761-768
Published online on: 29 May 2019

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miR‑25‑3p promotes glioma cell proliferation and migration by targeting FBXW7 and DKK3

Gang Peng, Chenxing Yang, Yi Liu, Chenfu Shen
Pages: 769-778
Published online on: 15 May 2019

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MicroRNA‑146a improves sepsis‑induced cardiomyopathy by regulating the TLR‑4/NF‑κB signaling pathway

Jin Xie, Lina Zhang, Xiaoyan Fan, Xiaoqing Dong, Zhe Zhang, Wenxing Fan
Pages: 779-785
Published online on: 10 June 2019

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Expression and function of miR‑155 in rat synovial fibroblast model of rheumatoid arthritis

Hewei Li, Ping Liu, Yanlin Gong, Jiali Liu, Feng Ruan
Pages: 786-792
Published online on: 15 May 2019

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Clinical characteristics of patients with premature acute coronary syndrome and adverse cardiovascular events after PCI

Xiao‑Jun Shi, Miao‑Nan Li, Ling Xuan, Hui Li, Bin Chen, Jun Zhang, Hong‑Ju Wang
Pages: 793-801
Published online on: 28 May 2019

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Efficacy and safety of N‑acetylcysteine therapy for idiopathic pulmonary fibrosis: An updated systematic review and meta‑analysis

Fanchao Fen, Jiarui Zhang, Zhichao Wang, Qi Wu, Xianmei Zhou
Pages: 802-816
Published online on: 15 May 2019

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Hypothermic properties of dexmedetomidine provide neuroprotection in rats following cerebral ischemia‑reperfusion injury

Jian Lu, Li‑Jun Liu, Jian‑Liang Zhu, Yi Shen, Zhi‑Wei Zhuang, Chang‑Lai Zhu
Pages: 817-825
Published online on: 24 May 2019

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Differential microRNA expression profile in the plasma of preeclampsia and normal pregnancies

Yan Zhong, Fufan Zhu, Yiling Ding
Pages: 826-832
Published online on: 03 June 2019

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Anti‑inflammatory effects of ethanol extract from the leaves and shoots of Cedrela odorata L. in cytokine‑stimulated keratinocytes

Han‑Sol Lee, Ji‑Won Park, Ok‑Kyoung Kwon, Yourim Lim, Jung Hee Kim, Soo‑Yong Kim, Nelson Zamora, Kattia Rosales, Sangho Choi, Sei‑Ryang Oh, Kyung‑Seop Ahn
Pages: 833-840
Published online on: 03 June 2019

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High expression of CDH3 predicts a good prognosis for colon adenocarcinoma patients

Yidong Xu, Jianpei Zhao, Xiaoyu Dai, Yangyang Xie, Mingjun Dong
Pages: 841-847
Published online on: 03 June 2019

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Immunological consequences following splenectomy in patients with liver cirrhosis

Yusuke Hirakawa, Toshiro Ogata, Tetsuro Sasada, Takuto Yamashita, Kyogo Itoh, Hiroyuki Tanaka, Koji Okuda
Pages: 848-856
Published online on: 03 June 2019

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Aged garlic extract ameliorates fatty liver and insulin resistance and improves the gut microbiota profile in a mouse model of insulin resistance

Toshio Maeda, Satomi Miki, Naoaki Morihara, Yoshiyuki Kagawa
Pages: 857-866
Published online on: 03 June 2019

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November-2026 Volume 32 Issue 5

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Development and internal validation of explainable machine learning models for predicting failure of first ambulation within 12 h after cesarean delivery: A retrospective cohort study

Lin Xiong, Youming Jin, Wei Li, Junjun Xiong, Hongmei Ding
Article Number: 326
Published online on: 02 October 2026

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Cilostazol ameliorates high glucose‑induced osteoblast dysfunction by modulating mitogen‑activated protein kinase signaling and the OPG/RANKL axis

Ji-Eun Kim, Ho Park
Article Number: 325
Published online on: 02 October 2026

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[Expression of Concern] Fisetin ameliorates atherosclerosis by regulating PCSK9 and LOX‑1 in apoE‑/‑ mice

Li Yan, Qingling Jia, Hui Cao, Chuan Chen, Sanli Xing, Yan Huang, Dingzhu Shen
Article Number: 324
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Advances in drug prevention and treatment of radiation‑induced lung injury (Review)

Shuo Liu, Minting Ma, Chanjun Zhen, Yang Zhao, Yuzhi Song, Qiuying An, Zhiguo Zhou, Wenwen Bai
Article Number: 323
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Effects of PD‑1/PD‑L1 on the malignant behavior of thyroid cancer cells through the TGF‑β/Smad signaling pathway

Xueji Wang, Jing Wang, Wei Cui, Jingxia Wang, Xueyan Zhang, Bingliang Zhang
Article Number: 322
Published online on: 29 September 2026

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Assessment of muscularis propria invasion in urothelial bladder carcinoma using continuous‑time random walk and stretched‑exponential models: Comparison with VI‑RADS and apparent diffusion coefficient

Yangying Wu, Xiaofang Zhu, Xiaolong Zhou, Canli Liu, Li Guo, Jingang Hao, Yunyun Shang
Article Number: 321
Published online on: 29 September 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin suppresses TNF‑α‑induced inflammatory injury and senescence of nucleus pulposus cells via the Sirt6/NF‑κB pathway

Tian Xie, Jun Yuan, Ling Mei, Ping Li, Ruijie Pan
Article Number: 320
Published online on: 29 September 2026

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Case Report Open Access

Tislelizumab‑induced psoriasis in a patient with hepatocellular carcinoma: A case report

Zhaochen Sun, Yuqi Zhou, Yeliang Mei, Yitian Chen
Article Number: 319
Published online on: 23 September 2026

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Functional heterogeneity of exosomes in hepatocellular carcinoma (Review)

Shiyan He, Xia Wu, Zhihao Wang, Xiong Zeng, Jing Lin, Jie Wang
Article Number: 318
Published online on: 23 September 2026

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Transforming growth factor β‑activated kinase 1 as a central integrator of immune‑microbiota crosstalk in colitis (Review)

Haoyu Dong, Sirui Wang, Ridong Lai, Guofeng Li
Article Number: 317
Published online on: 23 September 2026

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Integrated bioinformatics and clinical validation of oxidative stress‑associated genes in atrial fibrillation and chronic kidney disease

Jiyi Liu, Zezhou Xie, Huimin Yu, Fengzhi Sun, Ruifeng Wang, Yunbo Ba, Hao Huang, Xiaomeng Yin, Yu Wang
Article Number: 316
Published online on: 23 September 2026

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Pulmonary tuberculosis occurring during the diagnosis and treatment of sarcoidosis complicated by chylothorax: A case report 

Huai-Jie Wang, Xue Li, Wen-Ge Han, Yuan-Yuan Tang, Yan-Yan Zhang, Yu-Bing Wang, Yong Zhang, Xiao-Qi Zhang, Mei-Hua Qu
Article Number: 315
Published online on: 23 September 2026

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[Retracted] Knockdown of lncRNA CCEPR suppresses colorectal cancer progression

Yuxia Duan, Zhixue Fang, Zeya Shi, Ling Zhang
Article Number: 314
Published online on: 22 September 2026

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Prognostic significance of the blood urea nitrogen‑to‑serum albumin ratio in patients with septic shock

Jianhua Liu, Zhengxiang Wei, Sheng Ye, Min Shao
Article Number: 313
Published online on: 21 September 2026

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Endometrial thickness and cancer risk in asymptomatic postmenopausal women: Defining evidence‑based cut‑offs by systematic review and diagnostic meta‑analysis

Yan Song, Hongying Wu, Ting Qin, Nana Li, Meng Wang
Article Number: 312
Published online on: 21 September 2026

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Neurosyphilis presenting as status epilepticus and hemiplegia diagnosed by metagenomic next-generation sequencing: A case report

Hongshan Chu, Shibo Dong, Yuan Zhang, Ruisheng Duan, Ling Li
Article Number: 311
Published online on: 21 September 2026

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BBS10‑related Bardet‑Biedl syndrome with an atypical presentation of diabetes mellitus: A case report

Lei Zhang, Guoliang Li, Hong Chang, Yanhui Dong, Nana Sun, Rina Wu, Likun Han
Article Number: 310
Published online on: 16 September 2026

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Development of a recombinase‑aided amplification assay for rapid and sensitive detection of Pneumocystis jirovecii infection: A single‑center molecular study

Hanhan Zhu, Ben Yang, Ke Chen, Fang Xu, Meihua Qu, Yuanyuan Tang
Article Number: 309
Published online on: 16 September 2026

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Severe steroid‑refractory immune checkpoint inhibitor‑associated pneumonitis and exploration of potential biomarkers: A case report

Yan-Jun Xue, Ai-Zhen Xu, Xin-Da Yin, Lei Wei
Article Number: 308
Published online on: 16 September 2026

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Effects of ketamine and dexmedetomidine on ischemia‑ reperfusion injury in an experimental renal ischemia model

Muhammet Hanifi Erdoğan, Hakan Kardaş, Tülay Zenginkinet, Tuğba Bingöl Tanriverdi, Melek Güra Çelik
Article Number: 307
Published online on: 16 September 2026

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[Corrigendum] Ginsenoside Rg1 ameliorates apoptosis, senescence and oxidative stress in ox‑LDL‑induced vascular endothelial cells via the AMPK/SIRT3/p53 signaling pathway 

Tian-Jiao Lyu, Zi-Xiu Zhang, Jun Chen, Zong-Jun Liu
Article Number: 306
Published online on: 16 September 2026

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Carrageenan‑induced immunothrombotic models in rodents (Review)

Xiaomu Ma, Daihan Wu, Simin Lv
Article Number: 305
Published online on: 16 September 2026

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[Retracted] Role of peptidylarginine deiminase type 4 in gastric cancer 

Jiang Xin, Xiuqi Song
Article Number: 304
Published online on: 15 September 2026

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Immune checkpoint inhibitor‑induced myocarditis with myositis and/or myasthenia gravis overlap syndrome: A case series

Qing Sun, Qing Liu, Jiabin Zheng, Yanni Lou, Huijuan Cui, Junyu Ma, Yu Wang, Dantao Peng, Weihe Zhang, Renbin Wang
Article Number: 303
Published online on: 14 September 2026

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Cardiovascular health metrics and the risk of metabolic dysfunction‑associated steatosis liver disease: A meta‑analysis

Gang Fan, Hong Zuo, Bo Liu
Article Number: 302
Published online on: 14 September 2026

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Multiple relapses of cryptogenic organizing pneumonia: A case report

Sheng Xu, Beibei Li, Yanmin Li, Jian Sun, Qiang Wang
Article Number: 301
Published online on: 11 September 2026

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A diagnostic and classification model integrating cTnI, CK‑MB, MYO and NT‑proBNP for cardiovascular diseases

Huaxin Zhang, Jianan Wang, Qi Li, Tong Zhi, Xiandong Chang
Article Number: 300
Published online on: 11 September 2026

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A rare suprasellar lesion with multifocal central nervous system involvement in clinically diagnosed von Hippel‑Lindau disease: A case report

Zekai Wu, Lei Zhang, Meng Tan, Laian Zhang
Article Number: 299
Published online on: 11 September 2026

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Reversible osimertinib‑associated heart failure mimicking cancer recurrence in EGFR‑mutated non‑small cell lung cancer after pneumonectomy: A case report

Hirona Yokoyama, Nobuhito Hara, Rika Sasaki, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Takeshi Kawaguchi, Masatsugu Hamaji, Yuji Nitta, Maiko Takeda, Masayuki Takeda
Article Number: 298
Published online on: 11 September 2026

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Regenerative endodontic treatment for premolars with apical root segment separation and extensive periapical lesions secondary to severe inflammatory root resorption: A report of two cases

Qian Wu, Daniel J. Yen
Article Number: 297
Published online on: 11 September 2026

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[Retracted] Hsp70 inducer, 17‑allylamino‑demethoxygeldanamycin, provides neuroprotection via anti‑inflammatory effects in a rat model of traumatic brain injury

Youquan Gu, Jun Chen, Tianhong Wang, Chaoning Zhou, Zhaodong Liu, Lanhua Ma
Article Number: 296
Published online on: 10 September 2026

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Relapsed/refractory multiple myeloma with extramedullary plasmacytomas successfully rechallenged with humanized B‑cell maturation antigen‑directed chimeric antigen receptor T‑cell immunotherapy in an advanced disease stage: A case report

Runfeng Zhang, Lili Cheng, Jinghua Liu, Lu Zhang, Junling Zhuang
Article Number: 295
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] JWA regulates human esophageal squamous cell carcinoma and human esophageal cells through different mitogen‑activated protein kinase signaling pathways

Jie Lin, Tieliang Ma, Xiaodong Jiang, Zhijun Ge, Weiliang Ding, Yuanyuan Wu, Guojun Jiang, Jiake Feng, Guoxing Cui, Yongfei Tan
Article Number: 294
Published online on: 07 September 2026

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December-2026 Volume 32 Issue 6

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Protopanaxadiol‑type ginsenosides ameliorate PTSD‑like memory impairment and neuroinflammation in rats via suppression of TLR4/NF‑κB signaling

Bombi Lee
Article Number: 334
Published online on: 06 October 2026

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Analysis of risk factors and construction of a prediction model for postoperative deep vein thrombosis in patients with periarticular knee fractures

Jie Liang, Shuangli Lan, Shunjie Dang, Guiwen Luo, Yunkang Yang
Article Number: 333
Published online on: 06 October 2026

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Serum vitamin D and fracture risk in children and adolescents: A systematic review and meta‑analysis highlighting age and altitude as key moderators

Jinhua Ma, Bo Tang, Zhenjie Zhai, Zhancui Dang
Article Number: 332
Published online on: 06 October 2026

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Expression of Concern Open Access

[Expression of Concern] Wnt/β‑catenin signaling may induce senescence of chondrocytes in osteoarthritis

Weijun Li, Yan Xiong, Weiping Chen, Lidong Wu
Article Number: 331
Published online on: 06 October 2026

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Emerging therapeutic strategies for medication‑related osteonecrosis of the jaw: From microenvironmental modulation to precision medicine (Review)

Xiao-Lu Zheng, Xiao-Zhen Zhan, Jin-Jin Liu, Chang-Yun Leng, Lo Wing Ling, Qin Huang, Tai-Ying Chen, Jun-Yuan Li, Qing-Tong Zhao
Article Number: 330
Published online on: 05 October 2026

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Rehabilitation of paroxysmal sympathetic hyperactivity secondary to severe brain injury: A case report

Shouchang Xiang, Zhenzhen Gao, Zhiwen Zhu
Article Number: 329
Published online on: 05 October 2026

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Postoperative polymyalgia rheumatica after lung cancer resection in the absence of immune checkpoint inhibitors: A case report and literature review

Yan Wen, Yi Zhang, Man Wu, Peipei Zhang, Xuelian Jin
Article Number: 328
Published online on: 02 October 2026

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Imaging evolution of pancreatic intraductal oncocytic papillary neoplasm presenting with recurrent pancreatitis: A case report and literature review

Ying Liu, Hao Yu, Lianjun Zhou, Lin Wang
Article Number: 327
Published online on: 02 October 2026

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